Synaptic targets of commissural interneurons in the lumbar spinal cord of neonatal rats

Journal of Comparative Neurology

Volumn 461, Issue 4, 2003, Pages 429-440

  Birinyi, András ^a   Viszokay, Kornél ^a   Wéber, Ildikó ^a   Kiehn, Ole ^b   Antal, Miklós ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Biocytin; Biotinylated dextran amine; Locomotion; Motor neurons; Neural tracing

Indexed keywords

DEXTRAN DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BRAIN COMMISSURE; DENDRITE; GRAY MATTER; INTERNEURON; LUMBAR SPINAL CORD; MOTONEURON; NERVE FIBER; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPSE;

AFFERENT PATHWAYS; ANIMALS; ANIMALS, NEWBORN; AXONS; BIOTIN; DENDRITES; DEXTRANS; EFFERENT PATHWAYS; FLUORESCENT DYES; INTERNEURONS; LUMBOSACRAL REGION; MOTOR NEURONS; NERVE NET; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SPINAL CORD; SYNAPSES;

EID: 0038413629     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/cne.10696     Document Type: Article

References (45)

1. Antal M, Polgár E. 1993. Development of calbindin-D28k immunoreactive neurons in the embryonic chick lumbosacral spinal cord. Eur J Neurosci 5:782-794
2. Antal M, Berki ÁC, Horváth L, O'Donovan MJ. 1994. Developmental changes in the distribution of gamma-aminobutyric acid-immunoreactive neurons in the embryonic chick lumbosacral spinal cord. J Comp Neurol 343:228-236.
3. Berki AC, O'Donovan MJ, Antal M. 1995. Developmental expression of glycine immunoreactivity and its colocalization with GABA in the embryonic chick lumbosacral spinal cord. J Comp Neurol 362:583-596.
4. Birinyi A, Kjaer A, Viszokay K, Wéber I, Kiehn O, Antal M. 2001. Synaptic targets of commissural interneurons in the lumbar spinal cord of neonatal rats. Soc Neurosci Abstr 31:297.8.
5. Brown AG, Fyffee REW. 1980. Direct observations on the contacts made between Ia afferent fibers and a-motor neurones in the cat's lumbosacral spinal cord. J Physiol 313:121-140.
6. Buchanan JT. 1982. Identification of interneurons with contralateral caudal axons in the lamprey spinal cord: synaptic interactions and morphology. J Neurophysiol 47:961-975.
7. Buchanan JT. 1996. Lamprey spinal interneurons and their roles in swimming activity. Brain Behav Evol 48:287-296.
8. Buchanan JT. 1999a. Commissural interneurons in rhythm generation and intersegmental coupling in the lamprey spinal cord. J Neurophysiol 81:2037-2045.
9. Buchanan JT. 1999b. Segmental distribution of common synaptic input to spinal motor neurons during fictive swimming in the lamprey. J Neurophysiol. 82:1156-1163.
10. Butt SJ, Harris-Warrick RM, Kiehn O. 2002. Firing properties ofidentified interneuron populations in the mammalian hindlimb central pattern generator. J Neurosci 22:9961-9971.
11. Cazalets JR, Borde M, Clarac F. 1995. Localization and organization of central pattern generator for hindlimb locomotion in newborn rat. J Neurosci 15:4943-4951.
12. Cazalets JR, Borde M, Clarac F. 1996. The synaptic drive from the spinal locomotor network to motoneurons in the newborn rat. J Neurosci 16:298-306.
13. Cazalets JR, Bertrand S, Sqalli-Houssaini Y, Clarac F. 1998. GABAergic control of spinal locomotor networks in the neonatal rat. Ann NY Acad Sci 860:168-180.
14. Dale N. 1985. Reciprocal inhibitory interneurones in the Xenopus embryo spinal cord. 363:61-70.
15. Dolleman-Van der Weel MJ, Wouterlood FG, Witter MP. 1994. Multiple anterograde tracing combining Phaseolus vulgaris leucoagglutinin with rhodamine- and biotin-conjugated dextran amine. J Neurosci Methods 51:9-21.
16. Eide AL, Glover J, Kjaerulff O, Kiehn O. 1999. Characterization of commissural interneurons in the lumbar region of the neonatal rat spinal cord. J Comp Neurol 403:332-345.
17. Grillner S, Hongo T. 1972. Vestibulospinal effects on motoneruones and interneurones in the lumbosacral cord. Prog Brain Res 37:243-262.
18. Grillner, S, Deliagina Ö, Ekeberg A, El Marina RH, Hill A, Lansner G, Orlovsky N, Wallén P. 1995. Neuronal networks that co-ordinate locomotion and body orientation in lamprey. Trends Neurosci 18:270-279.
19. Hancock MB. 1984. Visualization of peptide-immunoreactive processes on serotonin-immunoreactive cells using two-colour immunoperoxidase staining. J Histochem Cytochem 32:311-314.
20. Harrison J, Jankowska E, Zytnicki D. 1985. Lamina VIII interneurons interposed in crossed reflex pathways in the cat. J Physiol 371:147-166.
21. Jankowska E. 1992. Interneuronal relay in spinal pathways from proprioceptors. Prog Neurobiol 38:335-378.
22. Jankowska E, Noga BR. 1990. Contralaterally projecting lamina VIII interneurones in middle lumbar segments in the cat. Brain Res 535: 327-330.
23. Jankowska E, Skoog B. 1986. Labelling of midlumbar neurones projecting to cat hindlimb motor neurones by transneuronal transport of a horseradish peroxidase conjugate. Neurosci Lett 71:163-168.
24. Kahn JA, Roberts A. 1982. Experiments on the central pattern generator for swimming in embryos of the amphibian Xenopus laevis. Philos Trans R Soc 296:213-228.
25. Kiehn O, Kjaerulff O. 1998. Distribution of central pattern generators for rhythmic motor outputs in the spinal cord of limbed vertebrates. Ann NY Acad Sci 860:110-129.
26. Kiehn O, Hounsgaard J, Sillar KT. 1997. Basic buildings blocks of vertebrate central pattern generators. In: Stein PSG, Grillner S, Selverston A, Stuart DG, editors. Neurons, networks and motor behavior. Cambridge, MA: MIT Press. p 47-59.
27. Kjaerulff O, Kiehn O. 1996. Distribution of networks generating and coordinating locomotor activity in the neonatal rat spinal cord in vitro: a lesion study. J Neurosci 16:5777-5794.
28. Kjaerulff O, Kiehn O. 1997. Crossed rhythmic synaptic input to motor neurons during selective activation of the contralateral spinal locomotor network. J Neurosci 17:9433-9447.
29. Kjaerulff O, Barajon I, Kiehn O. 1994. Sulphorhodamine-labelled cells in the neonatal rat spinal cord following chemically induced locomotor activity in vitro. J Physiol 478:265-273.
30. Kremer E, Lev-Tov A. 1997. Localization of the spinal network associated with generation of hindlimb locomotion in the neonatal rat and organization of its transverse coupling system. J Neurophysiol. 77:1155-1170.
31. Matsushita M. 1970. The axonal pathways of spinal neurones in the cat. J Comp Neurol 138:391-418.
32. Puskár Z, Antal M. 1997. Localization of last-order premotor interneurons in the lumbar spinal cord of rats. J Comp Neurol 389:377-389.
33. Rajakumar N, Elisevich K, Flumerfelt BA. 1993. Biotinylated dextran: A versatile anterograde and retrograde neuronal tracer. Brain Res 607: 47-53.
34. Ramon y Cajal. 1909. Histologie du système nerveux de l'homme et des vertèbrès. A. Paris: Maoine, vol. 1, p 93.
35. Roberts A. 1990. How does a nervous system produce behavior? A case study in neurobiology. Sci Prog Oxf 74:31-51.
36. Roberts A, Soffe SR, Wolf E, Yoshida M, Zhao FY. 1998. Central circuits controlling locomotion in young frog tadpoles. Ann NY Acad Sci 860: 19-34.
37. Scheibel ME, Sceibel AB. 1969. A structural analysis of spinal interneurons and Renshaw cells. In: Braizer MA, editor. The interneuron. Berkeley: University of California Press. p 159-208.
38. Schmidt BJ, Hochman S, MacLean JN. 1998. NMDA receptor-mediated oscillatory properties: potential role in rhythm generation in the mammalian spinal cord. Ann NY Acad Sci 860:189-202.
39. Sidibé M, Smith Y. 1996. Differential synaptic innervation of striatofugal neurons projecting to internal and external segments of the globus pallidus by thalamic afferents in the squirrel monkey. J Comp Neurol 365:445-465.
40. Stokke MF, Nissen UV, Glover JC, Kiehn O. 2002. Projection patterns of commissural interneurons in the lumbar spinal cord of the neonatal rat. J Comp Neurol 447:349-359.
41. Szentágothai J. 1951. Short propriospinal neurons and intrinsic connections of the spinal gray matter. Acta Morphol Acad Sci Hungar 1:81-94.
42. Tresch MC, Kiehn O. 1999. The coding of locomotor phase in population of interneurons in rostral and caudal segments of the neonatal rat lumbar spinal cord. J Neurophysiol 82:3563-3574.
43. Veenman CL, Reiner A, Honig MG. 1992. Biotinylated dextran amine as an anterograde tracer for single- and double-labeling studies. J Neurosci Methods 41:239-254.
44. Yoshida M, Roberts A, Soffe SR. 1998. Axon projections of reciprocal inhibitory interneurons in the spinal cord of young Xenopus tadpoles and implications for the pattern of inhibition during swimming and struggling. J Comp Neurol 400:504-518.
45. Willis W, Willis JC. 1966. Prperties of interneurones in the ventral spinal cord. Arch Ital Biol 104:354-386.