-
1
-
-
0033063774
-
The epidermal growth factor receptor and its inhibition in cancer therapy
-
Woodburn J. The epidermal growth factor receptor and its inhibition in cancer therapy. Pharmacol Ther 1999;82:241-50.
-
(1999)
Pharmacol. Ther.
, vol.82
, pp. 241-250
-
-
Woodburn, J.1
-
2
-
-
0032791110
-
Take your partners, please-signal diversification by the erbB family of receptor tyrosine kinases
-
Daly RJ. Take your partners, please-signal diversification by the erbB family of receptor tyrosine kinases. Growth Factors 1999;16:255-63.
-
(1999)
Growth Factors
, vol.16
, pp. 255-263
-
-
Daly, R.J.1
-
3
-
-
0029814271
-
A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
-
Tzahar E, Waterman H, Chen X, et al. A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 1996; 16:5276-87.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 5276-5287
-
-
Tzahar, E.1
Waterman, H.2
Chen, X.3
-
4
-
-
0033392005
-
Epidermal growth factor receptor inhibition in cancer therapy: Biology, rationale and preliminary clinical results
-
Huang SM, Harari PM. Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results. Invest New Drugs 1999;17:259-69.
-
(1999)
Invest. New Drugs
, vol.17
, pp. 259-269
-
-
Huang, S.M.1
Harari, P.M.2
-
5
-
-
0030206987
-
The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors
-
Rusch V, Mendelsohn J, Dmittrovsky E. The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors. Cytokine Growth Factor Rev 1996;7:133-41.
-
(1996)
Cytokine Growth Factor Rev.
, vol.7
, pp. 133-141
-
-
Rusch, V.1
Mendelsohn, J.2
Dmittrovsky, E.3
-
6
-
-
0028212870
-
The prognostic value of epidermal growth factor receptor (EGF-R) in primary breast cancer: Results of a 10 year follow-up study
-
Klijn JG, Look MP, Portengen H, et al. The prognostic value of epidermal growth factor receptor (EGF-R) in primary breast cancer: results of a 10 year follow-up study. Breast Cancer Res Treat 1994;29:73-83.
-
(1994)
Breast Cancer Res. Treat.
, vol.29
, pp. 73-83
-
-
Klijn, J.G.1
Look, M.P.2
Portengen, H.3
-
7
-
-
0029156963
-
Epidermal growth factor, oestrogen and progesterone receptor expression in primary ovarian cancer: Correlation with clinical outcome and response to chemotherapy
-
Scambia G, Benedetti-Panici P, Ferrandina G, et al. Epidermal growth factor, oestrogen and progesterone receptor expression in primary ovarian cancer: correlation with clinical outcome and response to chemotherapy. Br J Cancer 1995;72:361-6.
-
(1995)
Br. J. Cancer
, vol.72
, pp. 361-366
-
-
Scambia, G.1
Benedetti-Panici, P.2
Ferrandina, G.3
-
8
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon DJ, Godolphin W, Jones LA, et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989;244: 707-12.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
-
9
-
-
0033372557
-
Combination of EGFR, HER-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members
-
Xia W, Lau YK, Zhang HZ, et al. Combination of EGFR, HER-2/ neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members. Clin Cancer Res 1999;5: 4164-74.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 4164-4174
-
-
Xia, W.1
Lau, Y.K.2
Zhang, H.Z.3
-
10
-
-
0034611617
-
Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions
-
Smaill JB, Rewcastle GW, Loo JA, et al. Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions. J Med Chem 2000; 43:1380-97.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 1380-1397
-
-
Smaill, J.B.1
Rewcastle, G.W.2
Loo, J.A.3
-
11
-
-
13144266690
-
Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor
-
Fry DW, Bridges AJ, Denny WA, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A 1998;95: 12022-7.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 12022-12027
-
-
Fry, D.W.1
Bridges, A.J.2
Denny, W.A.3
-
12
-
-
0033968986
-
Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts
-
Vincent PW, Bridges AJ, Dykes DJ, et al. Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts. Cancer Chemother Pharmacol 2000;45:231-8.
-
(2000)
Cancer Chemother. Pharmacol.
, vol.45
, pp. 231-238
-
-
Vincent, P.W.1
Bridges, A.J.2
Dykes, D.J.3
-
13
-
-
2142708757
-
Challenges in the development of anti-epidermal growth factor receptor therapies in breast cancer
-
Arteaga CL, Truica CI. Challenges in the development of anti-epidermal growth factor receptor therapies in breast cancer. Semin Oncol 2004;31:3-8.
-
(2004)
Semin. Oncol.
, vol.31
, pp. 3-8
-
-
Arteaga, C.L.1
Truica, C.I.2
-
14
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
15
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 2004;304: 1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
16
-
-
0032825703
-
Differential control of VEGF synthesis and secretion in human glioma cells by IL-1 and EGF
-
Valter MM, Wiestler OD, Pietsche T. Differential control of VEGF synthesis and secretion in human glioma cells by IL-1 and EGF. Int J Dev Neurosci 1999;17:565-77.
-
(1999)
Int. J. Dev. Neurosci.
, vol.17
, pp. 565-577
-
-
Valter, M.M.1
Wiestler, O.D.2
Pietsche, T.3
-
17
-
-
0032972944
-
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice
-
Perrotte P, Matsumoto T, Inoue K, et al. Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice. Clin Cancer Res 1999;5: 257-65.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 257-265
-
-
Perrotte, P.1
Matsumoto, T.2
Inoue, K.3
-
18
-
-
0034896362
-
Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor
-
Ciardiello F, Caputo R, Bianco R, et al. Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Clin Cancer Res 2001;7:1459-65.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1459-1465
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
-
19
-
-
0028115003
-
Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer
-
Toi M, Hoshina S, Takayanagi T, Tominaga T. Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer. Jpn J Cancer Res 1994;85:1045-9.
-
(1994)
Jpn. J. Cancer Res.
, vol.85
, pp. 1045-1049
-
-
Toi, M.1
Hoshina, S.2
Takayanagi, T.3
Tominaga, T.4
-
20
-
-
0031789314
-
Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer
-
Ishigami SI, Arii S, Furutani M, et al. Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer. Br J Cancer 1998;78:1379-84.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1379-1384
-
-
Ishigami, S.I.1
Arii, S.2
Furutani, M.3
-
21
-
-
0033088075
-
Implication of vascular endothelial growth factor in the development and metastasis of human cancers
-
Arii S, Mori A, Uchida S, et al. Implication of vascular endothelial growth factor in the development and metastasis of human cancers. Hum Cell 1999;12:25-30.
-
(1999)
Hum. Cell
, vol.12
, pp. 25-30
-
-
Arii, S.1
Mori, A.2
Uchida, S.3
-
22
-
-
0033992036
-
Vascular endothelial growth factor as prognostic factor in renal cell carcinoma
-
Jacobsen J, Rasmuson T, Grankvist K, Ljungberg S. Vascular endothelial growth factor as prognostic factor in renal cell carcinoma. J Urol 2000;163:343-7.
-
(2000)
J. Urol.
, vol.163
, pp. 343-347
-
-
Jacobsen, J.1
Rasmuson, T.2
Grankvist, K.3
Ljungberg, S.4
-
23
-
-
0034650802
-
Regulation of angiogenesis via vascular endothelial growth factor receptors
-
[Review]
-
Veikkola T, Karkkainen M, Claesson-Welsh L, Alitalo K. Regulation of angiogenesis via vascular endothelial growth factor receptors [Review]. Cancer Res 2000;60:203-12.
-
(2000)
Cancer Res.
, vol.60
, pp. 203-212
-
-
Veikkola, T.1
Karkkainen, M.2
Claesson-Welsh, L.3
Alitalo, K.4
-
24
-
-
0034092011
-
Tumor angiogenesis: Past, present and the near future
-
[Review]
-
Kerbel RS. Tumor angiogenesis: past, present and the near future [Review]. Carcinogenesis 2000;21:505-15.
-
(2000)
Carcinogenesis
, vol.21
, pp. 505-515
-
-
Kerbel, R.S.1
-
25
-
-
0033513497
-
Targeting vascular endothelial growth factor (VEGF) for anti-tumor therapy, by anti-VEGF neutralizing monoclonal antibodies or by VEGF receptor tyrosine-kinase inhibitors
-
[Review]
-
Schlaeppi JM, Wood JM. Targeting vascular endothelial growth factor (VEGF) for anti-tumor therapy, by anti-VEGF neutralizing monoclonal antibodies or by VEGF receptor tyrosine-kinase inhibitors [Review]. Cancer Metastasis Rev 1999;18:473-81.
-
(1999)
Cancer Metastasis Rev.
, vol.18
, pp. 473-481
-
-
Schlaeppi, J.M.1
Wood, J.M.2
-
26
-
-
0036096775
-
Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice
-
Karashima T, Sweeney P, Slaton JW, et al. Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice. Clin Cancer Res 2002;8:1253-64.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 1253-1264
-
-
Karashima, T.1
Sweeney, P.2
Slaton, J.W.3
-
27
-
-
0036570203
-
ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase
-
Hirata A, Ogawa S, Kometani T, et al. ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase. Cancer Res 2002;62:2554-60.
-
(2002)
Cancer Res.
, vol.62
, pp. 2554-2560
-
-
Hirata, A.1
Ogawa, S.2
Kometani, T.3
-
28
-
-
0031984834
-
Expression of interleukin-8 correlates with vascularity in human gastric carcinomas
-
Kitadai Y, Haruma K, Sumii K, et al. Expression of interleukin-8 correlates with vascularity in human gastric carcinomas. Am J Pathol 1998;152:93-100.
-
(1998)
Am. J. Pathol.
, vol.152
, pp. 93-100
-
-
Kitadai, Y.1
Haruma, K.2
Sumii, K.3
-
29
-
-
0027097806
-
Interleukin-8 as a macrophage-derived mediator of angiogenesis
-
[see comments]
-
Koch AE, Polverini PJ, Kunkel SL, et al. Interleukin-8 as a macrophage-derived mediator of angiogenesis [see comments]. Science 1992;258:1798-801.
-
(1992)
Science
, vol.258
, pp. 1798-1801
-
-
Koch, A.E.1
Polverini, P.J.2
Kunkel, S.L.3
-
30
-
-
0030777119
-
Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis
-
Luca M, Huang S, Gershenwald JE, et al. Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis. Am J Pathol 1997;151:1105-13.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1105-1113
-
-
Luca, M.1
Huang, S.2
Gershenwald, J.E.3
-
31
-
-
0033571167
-
Hypoxia-induced elevation in interleukin-8 expression by human ovarian carcinoma cells
-
Xu L, Xie K, Mukaida N, Matsushima K, Fidler IJ. Hypoxia-induced elevation in interleukin-8 expression by human ovarian carcinoma cells. Cancer Res 1999;59:5822-9.
-
(1999)
Cancer Res.
, vol.59
, pp. 5822-5829
-
-
Xu, L.1
Xie, K.2
Mukaida, N.3
Matsushima, K.4
Fidler, I.J.5
-
32
-
-
8544249876
-
Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia
-
Enholm B, Paavonen K, Ristimaki A, et al. Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia. Oncogene 1997;14:2475-83.
-
(1997)
Oncogene
, vol.14
, pp. 2475-2483
-
-
Enholm, B.1
Paavonen, K.2
Ristimaki, A.3
-
33
-
-
0028822834
-
Mutant ras oncogenes upregulate VEGF/VPF expression: Implications for induction and inhibition of tumor angiogenesis
-
Rak J, Mitsuhashi Y, Bayko L, et al. Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis. Cancer Res 1995;55:4575-80.
-
(1995)
Cancer Res.
, vol.55
, pp. 4575-4580
-
-
Rak, J.1
Mitsuhashi, Y.2
Bayko, L.3
-
34
-
-
0017689377
-
Quantitative evaluation of anticancer agent activity in experimental animals
-
Schabel FM, Griswold DP, Laster WR, Corbett TH, Lloyd HH. Quantitative evaluation of anticancer agent activity in experimental animals. Pharmacol Ther 1977;1:411-35.
-
(1977)
Pharmacol. Ther.
, vol.1
, pp. 411-435
-
-
Schabel, F.M.1
Griswold, D.P.2
Laster, W.R.3
Corbett, T.H.4
Lloyd, H.H.5
-
36
-
-
21344448317
-
Gene expression profiling of anti-tumor efficacy of the irreversible EGFR/ErbB family inhibitor CI-1033 in vivo
-
Christensen JG, Messamore J, Ferguson E, et al. Gene expression profiling of anti-tumor efficacy of the irreversible EGFR/ErbB family inhibitor CI-1033 in vivo. AACR Proc 2000;41:1944.
-
(2000)
AACR Proc.
, vol.41
, pp. 1944
-
-
Christensen, J.G.1
Messamore, J.2
Ferguson, E.3
-
37
-
-
0024337366
-
EGF and TGF-α are potent chemoattractants for endothelial cells and EGF-like peptides are present at sites of tissue regeneration
-
Grotendorst GR, Soma Y, Takehara K, Charette M. EGF and TGF-α are potent chemoattractants for endothelial cells and EGF-like peptides are present at sites of tissue regeneration. J Cell Physiol 1989;139:617-23.
-
(1989)
J. Cell Physiol.
, vol.139
, pp. 617-623
-
-
Grotendorst, G.R.1
Soma, Y.2
Takehara, K.3
Charette, M.4
-
39
-
-
0030017822
-
Microvessel density, expression of proto-oncogenes, resistance-related proteins and incidence of metastases in primary ovarian carcinomas
-
Volm M, Koomagi R, Kaufmann M, Mattern J, Stammler G. Microvessel density, expression of proto-oncogenes, resistance-related proteins and incidence of metastases in primary ovarian carcinomas. Clin Exp Metast 1996;14:209-14.
-
(1996)
Clin. Exp. Metast.
, vol.14
, pp. 209-214
-
-
Volm, M.1
Koomagi, R.2
Kaufmann, M.3
Mattern, J.4
Stammler, G.5
-
40
-
-
0031884413
-
Expression of growth factors, growth-inhibiting factors, and their receptors in invasive breast cancer. II: Correlations with proliferation and angiogenesis
-
de Jong JS, van Diest PJ, van der Valk P, Baak JP. Expression of growth factors, growth-inhibiting factors, and their receptors in invasive breast cancer. II: Correlations with proliferation and angiogenesis. J Pathol 1998;184:53-7.
-
(1998)
J. Pathol.
, vol.184
, pp. 53-57
-
-
de Jong, J.S.1
van Diest, P.J.2
van der Valk, P.3
Baak, J.P.4
-
41
-
-
0001223491
-
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
-
Petit AM, Rak J, Hung MC, et al. Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors. Am J Pathol 1997;151:1523-30.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1523-1530
-
-
Petit, A.M.1
Rak, J.2
Hung, M.C.3
-
42
-
-
0031039923
-
Transforming growth factor-α-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation
-
Gille J, Swerlick RA, Caughman SW. Transforming growth factor-α-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation. EMBO J 1997;16:750-9.
-
(1997)
EMBO J.
, vol.16
, pp. 750-759
-
-
Gille, J.1
Swerlick, R.A.2
Caughman, S.W.3
-
43
-
-
0032851961
-
Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin)
-
Sliwkowski MX, Lofgren JA, Lewis GD, et al. Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin). Semin Oncol 1999;26:60-70.
-
(1999)
Semin. Oncol.
, vol.26
, pp. 60-70
-
-
Sliwkowski, M.X.1
Lofgren, J.A.2
Lewis, G.D.3
-
44
-
-
0036605053
-
Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-κB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines
-
Bancroft CC, Chen Z, Yeh J, et al. Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-κB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines. Int J Cancer 2002; 99:538-48.
-
(2002)
Int. J. Cancer
, vol.99
, pp. 538-548
-
-
Bancroft, C.C.1
Chen, Z.2
Yeh, J.3
-
45
-
-
0036828925
-
Correlation between color power Doppler sonographic measurement of breast tumor vasculature and immunohistochemical analysis of microvessel density for the quantitation of angiogenesis
-
Yang WT, Tse GM, Lam PK, Metreweli C, Chang J. Correlation between color power Doppler sonographic measurement of breast tumor vasculature and immunohistochemical analysis of microvessel density for the quantitation of angiogenesis. J Ultrasound Med 2002;21:1227-35.
-
(2002)
J. Ultrasound Med.
, vol.21
, pp. 1227-1235
-
-
Yang, W.T.1
Tse, G.M.2
Lam, P.K.3
Metreweli, C.4
Chang, J.5
-
46
-
-
0035154352
-
Evaluation of contrast-enhanced color Doppler ultrasound for the quantification of angiogenesis in vivo
-
Lassau N, Koscielny S, Opolon P, et al. Evaluation of contrast-enhanced color Doppler ultrasound for the quantification of angiogenesis in vivo. Invest Radiol 2001;36:50-5.
-
(2001)
Invest. Radiol.
, vol.36
, pp. 50-55
-
-
Lassau, N.1
Koscielny, S.2
Opolon, P.3
-
47
-
-
0033834124
-
Angiogenesis of endometrial carcinomas assessed by measurement of intratumoral blood flow, microvessel density, and vascular endothelial growth factor levels
-
Lee CN, Cheng WF, Chen CA, et al. Angiogenesis of endometrial carcinomas assessed by measurement of intratumoral blood flow, microvessel density, and vascular endothelial growth factor levels. Obstet Gynecol 2000;96:615-21.
-
(2000)
Obstet. Gynecol.
, vol.96
, pp. 615-621
-
-
Lee, C.N.1
Cheng, W.F.2
Chen, C.A.3
|