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Volumn 25, Issue 3 B, 2005, Pages 1881-1888

Down-regulation of Skp2 is correlated with p27-associated cell cycle arrest induced by phenylacetate in human prostate cancer cells

Author keywords

p27; Phenylacetate; Prostate cancer; Skp2

Indexed keywords

ANDROGEN; MESSENGER RNA; PHENYLACETIC ACID; PROTEIN KINASE B; PROTEIN P27; S PHASE KINASE ASSOCIATED PROTEIN 2;

EID: 21344459015     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (14)

References (49)
  • 1
    • 84928580276 scopus 로고
    • Studies on prostate cancer. I. The effect of castration, of estrogen, and androgen injection on serum phosphatases in metastatic carcinoma of the prostate
    • Huggins C and Hodges CV: Studies on prostate cancer. I. The effect of castration, of estrogen, and androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1: 293, 1941.
    • (1941) Cancer Res , vol.1 , pp. 293
    • Huggins, C.1    Hodges, C.V.2
  • 2
    • 0025974356 scopus 로고
    • Carcinoma of the prostate
    • Glitters RF: Carcinoma of the prostate. N Engl J Med 324: 235-245, 1991.
    • (1991) N Engl J Med , vol.324 , pp. 235-245
    • Glitters, R.F.1
  • 3
    • 0020058505 scopus 로고
    • Phenylacetic acid in human body fluids: High correlation between plasma and cerebrospinal fluid concentration values
    • Sndler M, Ruthven CR, Goodwin BL, Lees A and Stern GM: Phenylacetic acid in human body fluids: high correlation between plasma and cerebrospinal fluid concentration values. J Neurol Neurosurg Psychiatry 45: 366-368, 1982.
    • (1982) J Neurol Neurosurg Psychiatry , vol.45 , pp. 366-368
    • Sndler, M.1    Ruthven, C.R.2    Goodwin, B.L.3    Lees, A.4    Stern, G.M.5
  • 5
    • 0031460362 scopus 로고    scopus 로고
    • Hyperammonemic encephalopathy after chemotherapy. Survival after treatment with sodium benzoate and sodium phenylacetate
    • del Rosario M, Werlin SL and Lauer SJ: Hyperammonemic encephalopathy after chemotherapy. Survival after treatment with sodium benzoate and sodium phenylacetate. J Clin Gastroenterol 25: 682-684, 1997.
    • (1997) J Clin Gastroenterol , vol.25 , pp. 682-684
    • Del Rosario, M.1    Werlin, S.L.2    Lauer, S.J.3
  • 6
    • 0026730287 scopus 로고
    • Induction of erythroid differentiation and fetal hemoglobin production in human leukemic cells treated with phenylacetate
    • Samid D, Yeh A and Prasanna P: Induction of erythroid differentiation and fetal hemoglobin production in human leukemic cells treated with phenylacetate. Blood 80: 1576-1581, 1992.
    • (1992) Blood , vol.80 , pp. 1576-1581
    • Samid, D.1    Yeh, A.2    Prasanna, P.3
  • 7
    • 0026636474 scopus 로고
    • Phenlyacetate: A novel nontoxic inducer of tumor cell differentiation
    • Samid D, Shack S and Sherman LT: Phenlyacetate: a novel nontoxic inducer of tumor cell differentiation. Cancer Res 52: 1988-1992, 1992.
    • (1992) Cancer Res , vol.52 , pp. 1988-1992
    • Samid, D.1    Shack, S.2    Sherman, L.T.3
  • 8
    • 0027180685 scopus 로고
    • Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate
    • Samid D, Shack S and Myers CE: Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate. J Clin Invest 91: 2288-2295, 1993.
    • (1993) J Clin Invest , vol.91 , pp. 2288-2295
    • Samid, D.1    Shack, S.2    Myers, C.E.3
  • 10
    • 0029937059 scopus 로고    scopus 로고
    • Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate
    • Shack S, Miller A, Liu L, Prasanna P, Thibault A and Samid D: Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate. Cancer Res 2: 865-872, 1996.
    • (1996) Cancer Res , vol.2 , pp. 865-872
    • Shack, S.1    Miller, A.2    Liu, L.3    Prasanna, P.4    Thibault, A.5    Samid, D.6
  • 11
    • 0030861882 scopus 로고    scopus 로고
    • Impact of the putative differentiationing agents sodium phenylbutyrate and sodium phenylacetate on proliferation, differentiation and apoptosis of primary neoplastic myeloid cells
    • Gore SD, Samid D and Weng LJ: Impact of the putative differentiationing agents sodium phenylbutyrate and sodium phenylacetate on proliferation, differentiation and apoptosis of primary neoplastic myeloid cells. Clin Cancer Res 3: 1755-1762, 1997.
    • (1997) Clin Cancer Res , vol.3 , pp. 1755-1762
    • Gore, S.D.1    Samid, D.2    Weng, L.J.3
  • 12
  • 13
    • 0033623331 scopus 로고    scopus 로고
    • P27kip1 is the key mediator of phenylacetate induced cell cycle arrest in human prostate cancer cells
    • Onishi T, Yamakawa K, Omar E, Suzuki R and Kawamura J: p27kip1 is the key mediator of phenylacetate induced cell cycle arrest in human prostate cancer cells. Anticancer Res 20: 3075-3082, 2000.
    • (2000) Anticancer Res , vol.20 , pp. 3075-3082
    • Onishi, T.1    Yamakawa, K.2    Omar, E.3    Suzuki, R.4    Kawamura, J.5
  • 17
    • 0036893404 scopus 로고    scopus 로고
    • Low levels of p27kip1 protein expression in gastric adenocarcinoma is associated with disease progression and poor outcome
    • Nitti D, Belluco C, Mammano E, Marchet A, Ambrosi A, Mencarelli R, Segato P and Lise M: Low levels of p27kip1 protein expression in gastric adenocarcinoma is associated with disease progression and poor outcome. J Surg Oncol 81: 167-176, 2002.
    • (2002) J Surg Oncol , vol.81 , pp. 167-176
    • Nitti, D.1    Belluco, C.2    Mammano, E.3    Marchet, A.4    Ambrosi, A.5    Mencarelli, R.6    Segato, P.7    Lise, M.8
  • 18
    • 0037879095 scopus 로고    scopus 로고
    • p27kip1 is an independent predictor of recurrence after surgical resection in patients with small hepatocellular carcinoma
    • Armengol C, Boix L, Bachs O, Sole M, Fuster J, Sala M, Llovet JM, Rodes J and Bruix J: p27kip1 is an independent predictor of recurrence after surgical resection in patients with small hepatocellular carcinoma. J Hepatol 38: 591-597, 2003.
    • (2003) J Hepatol , vol.38 , pp. 591-597
    • Armengol, C.1    Boix, L.2    Bachs, O.3    Sole, M.4    Fuster, J.5    Sala, M.6    Llovet, J.M.7    Rodes, J.8    Bruix, J.9
  • 19
    • 0034816198 scopus 로고    scopus 로고
    • Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin e and p27kip1
    • Nakayama K-I, Hatakeyama S and Nakayama K: Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27kip1. Biochem Biophys Res 282: 853-860, 2001.
    • (2001) Biochem Biophys Res , vol.282 , pp. 853-860
    • Nakayama, K.-I.1    Hatakeyama, S.2    Nakayama, K.3
  • 20
    • 0033176887 scopus 로고    scopus 로고
    • SKP2 is required for ubiquitin-mediated degradation of CDK inhibitor p27
    • Carrano AC, Eytan E, Hershko A and Pagano M: SKP2 is required for ubiquitin-mediated degradation of CDK inhibitor p27. Nature Cell Biol 1: 193-199, 1999.
    • (1999) Nature Cell Biol , vol.1 , pp. 193-199
    • Carrano, A.C.1    Eytan, E.2    Hershko, A.3    Pagano, M.4
  • 21
    • 0035092687 scopus 로고    scopus 로고
    • The cell cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27
    • Ganoth D, Bornstein G, Ko TK, Larsen B, Tyers M, Pagano M and Hershko A: The cell cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27. Nature Cell Biol 3: 321-324, 2001.
    • (2001) Nature Cell Biol , vol.3 , pp. 321-324
    • Ganoth, D.1    Bornstein, G.2    Ko, T.K.3    Larsen, B.4    Tyers, M.5    Pagano, M.6    Hershko, A.7
  • 22
    • 0034643331 scopus 로고    scopus 로고
    • AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
    • Medema RH, Kops GJ, Bos JL and Burgering BMT: AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 404: 782-787, 2000.
    • (2000) Nature , vol.404 , pp. 782-787
    • Medema, R.H.1    Kops, G.J.2    Bos, J.L.3    Burgering, B.M.T.4
  • 25
    • 0039425278 scopus 로고    scopus 로고
    • Negative regulation of the Forkhead transcription factor FKHR by Akt
    • Tang ED, Nunez G, Barr FG and Guan KL: Negative regulation of the Forkhead transcription factor FKHR by Akt. J Biol Chem 274: 16741-16746, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 16741-16746
    • Tang, E.D.1    Nunez, G.2    Barr, F.G.3    Guan, K.L.4
  • 27
    • 0035990924 scopus 로고    scopus 로고
    • Inhibition of protein kinase B/Akt: Implications for cancer thrapy
    • Hill MM and Hemmings BA: Inhibition of protein kinase B/Akt: implications for cancer thrapy. Pharmacol Ther 93: 243-251, 2002.
    • (2002) Pharmacol Ther , vol.93 , pp. 243-251
    • Hill, M.M.1    Hemmings, B.A.2
  • 28
    • 0033618371 scopus 로고    scopus 로고
    • Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
    • Nakatani K, Thompson DA, Barthel A, Sakaue H, Liu W, Weigel RJ and Roth RA: Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J Biol Chem 274: 21528-21532, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 21528-21532
    • Nakatani, K.1    Thompson, D.A.2    Barthel, A.3    Sakaue, H.4    Liu, W.5    Weigel, R.J.6    Roth, R.A.7
  • 29
    • 0001457668 scopus 로고    scopus 로고
    • Amplication of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
    • Cheng JQ, Ruggeri B, Klein WM, Sonoda G, Altomare DA, Watson DK and Testa J: Amplication of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc Natl Acad Sci USA 93: 3636-3641, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3636-3641
    • Cheng, J.Q.1    Ruggeri, B.2    Klein, W.M.3    Sonoda, G.4    Altomare, D.A.5    Watson, D.K.6    Testa, J.7
  • 34
    • 0030777104 scopus 로고    scopus 로고
    • Disruption oh the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma
    • Guldberg P, Straten Pt, Birck A, Ahrenkiel V, Lirkin AF and Zeuthen J: Disruption oh the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res 57: 3660-3663, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3660-3663
    • Guldberg, P.1    Straten, Pt.2    Birck, A.3    Ahrenkiel, V.4    Lirkin, A.F.5    Zeuthen, J.6
  • 37
    • 0034724443 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells
    • Persad S, Attwell S, Gray V, Delcommenne M, Troussard A, Sanghera J and Dedhar S: Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells. Proc Natl Acad Sci USA 97: 3207-3212, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3207-3212
    • Persad, S.1    Attwell, S.2    Gray, V.3    Delcommenne, M.4    Troussard, A.5    Sanghera, J.6    Dedhar, S.7
  • 38
    • 0035916325 scopus 로고    scopus 로고
    • PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27kip1 through the ubiquitin E3 ligase SCFskp2
    • Mamillapalli R, Gavrilova N, Mihaylova VT, Tsvetkov LM, Wu H, Zhang H and Sun H: PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27kip1 through the ubiquitin E3 ligase SCFskp2. Curr Biol 11: 263-267, 2001.
    • (2001) Curr Biol , vol.11 , pp. 263-267
    • Mamillapalli, R.1    Gavrilova, N.2    Mihaylova, V.T.3    Tsvetkov, L.M.4    Wu, H.5    Zhang, H.6    Sun, H.7
  • 39
    • 0029995670 scopus 로고    scopus 로고
    • Thiazolidinediones in the treatment of insulin resistance and typeII diabetes
    • Saltiel AR and Olefsky JM: Thiazolidinediones in the treatment of insulin resistance and typeII diabetes. Diabetes 45: 1661-1669, 1996.
    • (1996) Diabetes , vol.45 , pp. 1661-1669
    • Saltiel, A.R.1    Olefsky, J.M.2
  • 40
    • 0029016829 scopus 로고
    • An antidiabetic thiazoidinedione is a high affinity ligand for peroxisome proliferator-activated receptor g (PPARg)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkinson WO, Wilson TM and Kliewer SA: An antidiabetic thiazoidinedione is a high affinity ligand for peroxisome proliferator-activated receptor g (PPARg). J Biol Chem 270: 12953-12956, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkinson, W.O.4    Wilson, T.M.5    Kliewer, S.A.6
  • 42
    • 0032145363 scopus 로고    scopus 로고
    • Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effects against human prostate cancer both in vitro and in vivo
    • Kubota T, Koshizuka K, Williamson EA, Asou H, Said JW, Holden S, Miyoshi I and Koeffler HP: Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effects against human prostate cancer both in vitro and in vivo. Cancer Res 58: 3344-3352, 1998.
    • (1998) Cancer Res , vol.58 , pp. 3344-3352
    • Kubota, T.1    Koshizuka, K.2    Williamson, E.A.3    Asou, H.4    Said, J.W.5    Holden, S.6    Miyoshi, I.7    Koeffler, H.P.8
  • 44
    • 0034071190 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ as a novel target in cancer therapy: Binding and activation by an aromatic fatty acid with clinical antitumor activity
    • Samid D, Wells M, Greene ME, Shen W, Palmer CAN and Thibault A: Peroxisome proliferator-activated receptor γ as a novel target in cancer therapy: binding and activation by an aromatic fatty acid with clinical antitumor activity. Clin Cancer Res 6: 933-941, 2000.
    • (2000) Clin Cancer Res , vol.6 , pp. 933-941
    • Samid, D.1    Wells, M.2    Greene, M.E.3    Shen, W.4    Can, P.5    Thibault, A.6
  • 45
    • 0035872439 scopus 로고    scopus 로고
    • Differentiation of human neuroblastoma by phenylacetate is mediated by peroxisome proliferator-activated receptor γ
    • Han S, Wada RK and Sidell N: Differentiation of human neuroblastoma by phenylacetate is mediated by peroxisome proliferator-activated receptor γ. Cancer Res 61: 3998-4002, 2001.
    • (2001) Cancer Res , vol.61 , pp. 3998-4002
    • Han, S.1    Wada, R.K.2    Sidell, N.3
  • 46
    • 0036645405 scopus 로고    scopus 로고
    • Clinical and pathological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma; modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis
    • Masuda TA, Inoue H, Sonoda H, Mine S, Yoshikawa Y, Nakayama K, Nakayama K and Mori M: Clinical and pathological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma; modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis. Cancer Res 62: 3819-3825, 2002.
    • (2002) Cancer Res , vol.62 , pp. 3819-3825
    • Masuda, T.A.1    Inoue, H.2    Sonoda, H.3    Mine, S.4    Yoshikawa, Y.5    Nakayama, K.6    Nakayama, K.7    Mori, M.8
  • 47
    • 0037047477 scopus 로고    scopus 로고
    • Inverse relationship between p27/Kip.1 and the F-box protein Skp2 in human astrocytic gliomas by immunohistochemistry and Western blot
    • Schiffer D, Cavalla P, Fiano V, Ghimenti C and Piva R: Inverse relationship between p27/Kip.1 and the F-box protein Skp2 in human astrocytic gliomas by immunohistochemistry and Western blot. Neurosci Lett 328: 125-128, 2002.
    • (2002) Neurosci Lett , vol.328 , pp. 125-128
    • Schiffer, D.1    Cavalla, P.2    Fiano, V.3    Ghimenti, C.4    Piva, R.5
  • 48
    • 0038679293 scopus 로고    scopus 로고
    • Inverse relationship between Skp2 ubiquitin ligase and the cyclin dependent kinase inhibitor p27kip1 in prostate cancer
    • Ben-Izhak O, Lahav-Baratz S, Meretyk S, Ben-Eliezer S, Sabo E, Dirnfeld M, Cohen S and Ciechanover A: Inverse relationship between Skp2 ubiquitin ligase and the cyclin dependent kinase inhibitor p27kip1 in prostate cancer. J Urol 170: 241-245, 2003.
    • (2003) J Urol , vol.170 , pp. 241-245
    • Ben-Izhak, O.1    Lahav-Baratz, S.2    Meretyk, S.3    Ben-Eliezer, S.4    Sabo, E.5    Dirnfeld, M.6    Cohen, S.7    Ciechanover, A.8
  • 49
    • 0037379776 scopus 로고    scopus 로고
    • Expession of the F-box protein SKP2 induces hyperplasia, dysplasia, and low-grade carcinoma in the mouse prostate
    • Shim EH, Johnson L, Noh HL, Kim YJ, Sun H, Zeiss C and Zhang H: Expession of the F-box protein SKP2 induces hyperplasia, dysplasia, and low-grade carcinoma in the mouse prostate. Cancer Res 63: 1583-1588, 2003.
    • (2003) Cancer Res , vol.63 , pp. 1583-1588
    • Shim, E.H.1    Johnson, L.2    Noh, H.L.3    Kim, Y.J.4    Sun, H.5    Zeiss, C.6    Zhang, H.7


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