The dual role of prostaglandin E2 in excitotoxicity and preconditioning-induced neuroprotection

European Journal of Pharmacology

Volumn 517, Issue 1-2, 2005, Pages 17-27

  Gendron, Tania F ^a,b   Brunette, Eric ^a   Tauskela, Joseph S ^a   Morley, Paul ^a,b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Ca2+; Cyclooxygenase 2; Oxygen glucose deprivation; Preconditioning; Primary cortical cultures; Prostaglandin E2

Indexed keywords

CALCIUM; CYCLOOXYGENASE 2; GLUCOSE; MESSENGER RNA; PROSTAGLANDIN E2; PROSTANOID RECEPTOR;

ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN HYPOXIA; BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL ACTIVATION; CELL DEATH; CONTROLLED STUDY; ENZYME INHIBITION; EXCITOTOXICITY; FETUS; GLUCOSE BRAIN LEVEL; HYPOGLYCEMIA; IN VITRO STUDY; MOLECULAR DYNAMICS; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING;

ANIMALS; BRAIN; CALCIUM; CELL DEATH; CELL HYPOXIA; CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DIBENZ(B,F)(1,4)OXAZEPINE-10(11H)-CARBOXYLIC ACID, 8-CHLORO-, 2-ACETYLHYDRAZIDE; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; GENE EXPRESSION; GLUCOSE; MALE; NEUROGLIA; NEURONS; PREGNANCY; PROSTAGLANDIN ANTAGONISTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROSTAGLANDIN E; RNA, MESSENGER;

EID: 21344452607     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.05.031     Document Type: Article

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