The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax

FEBS Letters

Volumn 579, Issue 17, 2005, Pages 3695-3700

  Campello, Silvia ^a   De Marchi, Umberto ^a   Szabò, Ildikò ^a   Tombola, Francesco ^a   Martinou, Jean Claude ^b   Zoratti, Mario ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Apoptosis; Bax; Mitochondria; Patch clamp; Permeability transition pore

Indexed keywords

CYCLOSPORIN A; ETOPOSIDE; PROTEIN BAX; STAUROSPORINE;

APOPTOSIS; ARTICLE; CANCER CELL; CELL ISOLATION; CELL ORGANELLE; CELL SWELLING; COLON CARCINOMA; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; MEMBRANE CHANNEL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN INDUCTION;

BCL-2-ASSOCIATED X PROTEIN; CALCIUM; CARCINOMA; CATIONS, DIVALENT; COLONIC NEOPLASMS; HUMANS; ION CHANNELS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL SWELLING; MUTATION; PATCH-CLAMP TECHNIQUES; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 21244503559     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.05.055     Document Type: Article

References (33)

1. 2+-induced permeability transition of isolated mitochondria J. Biol. Chem. 279 2004 37415 37422
2. M. Narita, S. Shimizu, T. Ito, T. Chittenden, R.J. Lutz, H. Matsuda, and Y. Tsujimoto Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria Proc. Natl. Acad. Sci. USA 95 1998 14681 14686
3. J.G. Pastorino, M. Tafani, R.J. Rothman, A. Marcineviciute, J.B. Hoek, and J.L. Farber Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore J. Biol. Chem. 274 1999 31734 31739
4. J.M. Jürgensmeier, Z. Xie, Q. Deveraux, L. Ellerby, D. Bredesen, and J.C. Reed Bax directly induces release of cytochrome c from isolated mitochondria Proc. Natl. Acad. Sci. USA 95 1998 4997 5002
5. O. von Hasen, C. Renken, G. Perkins, R.M. Kluck, E. Bossy-Wetzel, and D.D. Newmeyer Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release J. Cell Biol. 150 2000 1027 1036
6. 2+-independent mechanisms that are regulated by Bax J. Biol. Chem. 276 2001 19066 19071
7. T. Nagakawa, S. Shimizu, T. Watanabe, O. Yamaguchi, K. Otsu, H. Yamagata, H. Inohara, T. Kubo, and Y. Tsujimoto Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death Nature 434 2005 652 658
8. C.P. Baines, R.A. Kaiser, N.H. Purcell, H. Osinska, M.A. Hambleton, E.W. Brunskill, M.R. Sayen, R.A. Gottlieb, G.W. Dorn, J. Robbins, and J.D. Molkentin Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death Nature 434 2005 658 662
9. B.M. Polster, G. Basanez, M. Young, M. Suzuki, and G. Fiskum Inhibition of Bax-induced cytochrome c release from neural cell and brain mitochondria by dibucaine and propanolol J. Neurosci. 23 2003 2735 2743
10. T. Kuwana, M.R. Mackey, G. Perkins, M.H. Ellisman, M. Latterich, R. Schneiter, D.R. Green, and D.D. Newmeyer Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane Cell 111 2002 331 342
11. I. Marzo, C. Brenner, N. Zamzami, S.A. Susin, G. Beutner, D. Brdiczka, R. Rémy, Z.-H. Xie, J.C. Reed, and G. Kroemer The permeability transition pore complex: a target for apoptosis regulation by caspases and Bcl-2-related proteins J. Exp. Med. 187 1998 1261 1271
12. I. Marzo, C. Brenner, N. Zamzami, J.M. Jurgensmeier, S.A. Susin, H.L. Vieira, M.C. Prevost, Z. Xie, S. Matsuyama, J.C. Reed, and G. Kroemer Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis Science 281 1998 2027 2031
13. I. Szabò, and M. Zoratti The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A J. Biol. Chem. 266 1991 3376 3379
14. I. Szabò, and M. Zoratti The mitochondrial megachannel is the permeability transition pore J. Bioenerg. Biomembr. 24 1992 111 117
15. I. Szabò, P. Bernardi, and M. Zoratti Modulation of the mitochondrial megachannel by divalent cations and protons J. Biol. Chem. 267 1992 2940 2946
16. S.A. Andrabi, I. Sayeed, D. Siemen, G. Wolf, and T.F.W. Horn Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin FASEB J. 18 2004 869 871
17. C. Loupatatzis, G. Seitz, P. Schönfeld, F. Lang, and D. Siemen Single channel currents of the permeability transition pore from the inner mitochondrial membrane of rat liver and a human hepatoma cell line Cell. Physiol. Biochem. 12 2002 269 278
18. X. Roucou, S. Montessuit, B. Antonsson, and J.-C. Martinou Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein Biochem. J. 368 2002 915 921
19. 2+ -reversible inhibition of the mitochondrial megachannel by ubiquinone analogues FEBS Lett. 480 2000 89 94
20. S. Desagher, and J.-C. Martinou Mitochondria as the central control point of apoptosis Trends Cell Biol. 10 2000 369 377
21. S. Frank, B. Gaume, E.S. Bergmann-Leitner, W.W. Leitner, E.G. Robert, F. Catez, C.L. Smith, and R.J. Youle The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis Dev. Cell 1 2001 515 525
22. M. Karbowski, Y.-J. Lee, B. Gaume, S.-Y. Jeong, S. Frank, A. Nechustan, A. Santel, M. Fuller, C.L. Smith, and R.J. Youle Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis J. Cell Biol. 159 2002 931 938
23. M. Vyssokikh, and D. Brdiczka VDAC and peripheral channelling complexes in health and disease Mol. Cell. Biochem. 256-257 2004 117 126
24. M. Colombini Voltage gating in the mitochondrial channel, VDAC J. Membr. Biol. 111 1989 103 111
25. R. Benz Biophysical properties of porin pores from mitochondrial outer membranes of eukaryotic cells Experientia 46 1990 131 137
26. R. Benz Permeation of hydrophilic solutes through mitochondrial outer membranes: review on mitochondrial porin Biochim. Biophys. Acta Biomembr. 1197 1994 167 196
27. A.M. Cesura, E. Pinard, R. Schubenel, V. Goetschy, A. Friedlein, H. Langen, P. Polcic, M.A. Forte, P. Bernardi, and J.A. Kemp The voltage-dependent anion channel is the target for a new class of inhibitors of the mitochondrial permeability transition pore J. Biol. Chem. 278 2003 49812 49818
28. M. Zoratti, and I. Szabò The mitochondrial permeability transition Biochim. Biophys. Acta Rev. Biomembr. 1241 1995 139 176
29. N. Brustovetsky, and J.M. Dubinsky Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria J. Neurosci. 20 2000 8229 8237
30. L. He, and J.J. Lemasters Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function? FEBS Lett. 512 2002 1 7
31. M. Zoratti, I. Szabò, and U. De Marchi Mitochondrial permeability transitions: how many doors to the house? Biochim. Biophys. Acta Bioenerg. 1706 2005 40 52
32. L. Scorrano, A. Nicolli, E. Basso, V. Petronilli, and P. Bernardi Two modes of activation of the permeability transition pore: the role of mitochondrial cyclophilin Mol. Cell. Biochem. 174 1997 181 184
33. E. Basso, L. Fante, J. Fowlkes, V. Petronilli, M.A. Forte, and P. Bernardi Properties of the permeability transition pore in mitochondria devoid of cyclophilin D J. Biol. Chem. 280 2005 18558 18561