Requirement for yeast RAD26, a homolog of the human CSB gene, in elongation by RNA polymerase II

Molecular and Cellular Biology

Volumn 21, Issue 24, 2001, Pages 8651-8656

  Lee, S K ^a   Yu, S L ^a   Prakash, L ^a   Prakash, S ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN CSB; PROTEIN RAD26; RNA POLYMERASE II; UNCLASSIFIED DRUG;

ARTICLE; COCKAYNE SYNDROME; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; GENE MUTATION; HUMAN; IN VIVO STUDY; NONHUMAN; PHOTOSENSITIVITY DISORDER; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

CELL CYCLE PROTEINS; CELL DIVISION; COCKAYNE SYNDROME; DNA HELICASES; DNA REPAIR ENZYMES; FUNGAL PROTEINS; HUMANS; MUTATION; RNA; RNA POLYMERASE II; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE PROTEINS; TIME FACTORS; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS;

SACCHAROMYCES CEREVISIAE;

EID: 0035201056     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.24.8651-8656.2001     Document Type: Article

References (23)

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4. Reduced RNA polymerase II transcription in extracts of Cockayne syndrome and xeroderma pigmentosum/Cockayne syndrome cells
5. 6-Azauracil inhibition of GTP biosynthesis in Saccharomyces cerevisiae
6. RAD26, the yeast homolog of human Cockayne's syndrome group B gene, encodes a DNA dependent ATPase
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13. Cockayne syndrome: Review of 140 cases
14. Mutations in the second largest subunit of RNA polymerase II cause 6-azauracil sensitivity in yeast and increased transcriptional arrest in vitro
15. Nascent RNA cleavage by transcription elongation complexes
16. Cockayne syndrome group B protein enhances elongation by RNA polymerase II
17. Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II
18. Saccharomyces cerevisiae transcription elongation mutants are defective in PUR5 induction in response to nucleotide depletion
19. The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex
20. RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6
21. Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells
22. Activation of p53 or loss of the Cockayne syndrome group B repair protein causes metaphase fragility of human U1, U2, and 5S genes