메뉴 건너뛰기




Volumn 90, Issue 6, 2005, Pages 3371-3380

Growth hormone replacement is important for the restoration of parathyroid hormone sensitivity and improvement in bone metabolism in older adult growth hormone-deficient patients

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CARBOXY TERMINAL TELOPEPTIDE; COLLAGEN TYPE 1; CYCLIC AMP; GROWTH HORMONE; PARATHYROID HORMONE; PHOSPHATE; PROCOLLAGEN; HUMAN GROWTH HORMONE;

EID: 21244441974     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-1650     Document Type: Article
Times cited : (28)

References (54)
  • 2
    • 0015349640 scopus 로고
    • Absence of sleep-related growth hormone peaks in aged normal subjects and in acromegaly
    • Carlson HE, Gillin JC, Gorden P, Snyder F 1972 Absence of sleep-related growth hormone peaks in aged normal subjects and in acromegaly. J Clin Endocrinol Metab 34:1102-1105
    • (1972) J Clin Endocrinol Metab , vol.34 , pp. 1102-1105
    • Carlson, H.E.1    Gillin, J.C.2    Gorden, P.3    Snyder, F.4
  • 5
    • 0025787687 scopus 로고
    • Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men
    • Iranmanesh A, Lizarralde G, Veldhuis JD 1991 Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men. J Clin Endocrinol Metab 73:1081-1088
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 1081-1088
    • Iranmanesh, A.1    Lizarralde, G.2    Veldhuis, J.D.3
  • 6
    • 0014851083 scopus 로고
    • Adult lean body mass declines with age: Some longitudinal observations
    • Forbes GB, Reina JC 1970 Adult lean body mass declines with age: some longitudinal observations. Metabolism 19:653-663
    • (1970) Metabolism , vol.19 , pp. 653-663
    • Forbes, G.B.1    Reina, J.C.2
  • 7
    • 0019505458 scopus 로고
    • Differential changes in bone mineral density of the appendicular and axial skeleton with aging: Relationship to spinal osteoporosis
    • Riggs BL, Wahner HW, Dunn WL, Mazess RB, Offord KP, Melton 3rd LJ 1981 Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest 67:328-335
    • (1981) J Clin Invest , vol.67 , pp. 328-335
    • Riggs, B.L.1    Wahner, H.W.2    Dunn, W.L.3    Mazess, R.B.4    Offord, K.P.5    Melton III, L.J.6
  • 8
    • 0022370713 scopus 로고
    • Growth hormone, body composition, and aging
    • Rudman D 1985 Growth hormone, body composition, and aging. J Am Geriatr Soc 33:800-807
    • (1985) J Am Geriatr Soc , vol.33 , pp. 800-807
    • Rudman, D.1
  • 10
    • 0030062657 scopus 로고    scopus 로고
    • Beyond the somatopause: Growth hormone deficiency in adults over the age of 60 years
    • Toogood AA, O'Neill PA, Shalet SM 1996 Beyond the somatopause: growth hormone deficiency in adults over the age of 60 years. J Clin Endocrinol Metab 81:460-465
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 460-465
    • Toogood, A.A.1    O'Neill, P.A.2    Shalet, S.M.3
  • 11
    • 0030918539 scopus 로고    scopus 로고
    • Elderly patients with adult-onset growth hormone deficiency are not osteopenic
    • Toogood AA, Adams JE, O'Neill PA, Shalet SM 1997 Elderly patients with adult-onset growth hormone deficiency are not osteopenic. J Clin Endocrinol Metab 82:1462-1466
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1462-1466
    • Toogood, A.A.1    Adams, J.E.2    O'Neill, P.A.3    Shalet, S.M.4
  • 12
    • 0027363782 scopus 로고
    • Reduced bone mineral content in adult patients with growth hormone deficiency
    • Copenh
    • Rosen T, Hansson T, Granhed H, Szucs J, Bengtsson BA 1993 Reduced bone mineral content in adult patients with growth hormone deficiency. Acta Endocrinol (Copenh) 129:201-206
    • (1993) Acta Endocrinol , vol.129 , pp. 201-206
    • Rosen, T.1    Hansson, T.2    Granhed, H.3    Szucs, J.4    Bengtsson, B.A.5
  • 13
    • 0023869716 scopus 로고
    • Local and systemic factors in the pathogenesis of osteoporosis
    • Raisz LG 1988 Local and systemic factors in the pathogenesis of osteoporosis. N Engl J Med 318:818-828
    • (1988) N Engl J Med , vol.318 , pp. 818-828
    • Raisz, L.G.1
  • 14
    • 0029763741 scopus 로고    scopus 로고
    • Growth hormone, insulin-like growth factors, and bone remodelling
    • Eriksen EF, Kassem M, Langdahl B 1996 Growth hormone, insulin-like growth factors, and bone remodelling. Eur J Clin Invest 26:525-534
    • (1996) Eur J Clin Invest , vol.26 , pp. 525-534
    • Eriksen, E.F.1    Kassem, M.2    Langdahl, B.3
  • 16
    • 0027453742 scopus 로고
    • New markers of bone and collagen turnover in children and adults with growth hormone deficiency
    • Sartorio A, Conti A, Monzani M 1993 New markers of bone and collagen turnover in children and adults with growth hormone deficiency. Postgrad Med J 69:846-850
    • (1993) Postgrad Med J , vol.69 , pp. 846-850
    • Sartorio, A.1    Conti, A.2    Monzani, M.3
  • 17
    • 0024854194 scopus 로고
    • The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
    • Salomon F, Cuneo RC, Hesp R, Sonksen PH 1989 The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med 321:1797-1803
    • (1989) N Engl J Med , vol.321 , pp. 1797-1803
    • Salomon, F.1    Cuneo, R.C.2    Hesp, R.3    Sonksen, P.H.4
  • 20
    • 0026767143 scopus 로고
    • The effect of growth hormone administration in growth hormone deficient adults on bone, protein, carbohydrate and lipid homeostasis, as well as on body composition
    • Oxf
    • Binnerts A, Swart GR, Wilson JH, Hoogerbrugge N, Pols HA, Birkenhager JC, Lamberts SW 1992 The effect of growth hormone administration in growth hormone deficient adults on bone, protein, carbohydrate and lipid homeostasis, as well as on body composition. Clin Endocrinol (Oxf) 37:79-87
    • (1992) Clin Endocrinol , vol.37 , pp. 79-87
    • Binnerts, A.1    Swart, G.R.2    Wilson, J.H.3    Hoogerbrugge, N.4    Pols, H.A.5    Birkenhager, J.C.6    Lamberts, S.W.7
  • 21
    • 0033824363 scopus 로고    scopus 로고
    • GH deficiency in the elderly: The case for GH replacement
    • Oxf
    • Shalet SM 2000 GH deficiency in the elderly: the case for GH replacement. Clin Endocrinol (Oxf) 53:279-280
    • (2000) Clin Endocrinol , vol.53 , pp. 279-280
    • Shalet, S.M.1
  • 22
    • 0030804947 scopus 로고    scopus 로고
    • Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis
    • Lindsay R, Nieves J, Formica C, Henneman E, Woelfert L, Shen V, Dempster D, Cosman F 1997 Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis. Lancet 350:550-555
    • (1997) Lancet , vol.350 , pp. 550-555
    • Lindsay, R.1    Nieves, J.2    Formica, C.3    Henneman, E.4    Woelfert, L.5    Shen, V.6    Dempster, D.7    Cosman, F.8
  • 23
    • 0023749677 scopus 로고
    • In vivo distribution of parathyroid hormone receptors in bone: Evidence that a predominant osseous target cell is not the mature osteoblast
    • Rouleau MF, Mitchell J, Goltzman D 1988 In vivo distribution of parathyroid hormone receptors in bone: evidence that a predominant osseous target cell is not the mature osteoblast. Endocrinology 123:187-191
    • (1988) Endocrinology , vol.123 , pp. 187-191
    • Rouleau, M.F.1    Mitchell, J.2    Goltzman, D.3
  • 24
    • 0037291852 scopus 로고    scopus 로고
    • Parathyroid hormone secretory pattern, circulating activity, and effect on bone turnover in adult growth hormone deficiency
    • Ahmad AM, Hopkins MT, Fraser WD, Ooi CG, Durham BH, Vora JP 2003 Parathyroid hormone secretory pattern, circulating activity, and effect on bone turnover in adult growth hormone deficiency. Bone 32:170-179
    • (2003) Bone , vol.32 , pp. 170-179
    • Ahmad, A.M.1    Hopkins, M.T.2    Fraser, W.D.3    Ooi, C.G.4    Durham, B.H.5    Vora, J.P.6
  • 26
    • 0020460601 scopus 로고
    • Statistics in medical journals
    • Altman DG 1982 Statistics in medical journals. Stat Med 1:59-71
    • (1982) Stat Med , vol.1 , pp. 59-71
    • Altman, D.G.1
  • 27
    • 0019869234 scopus 로고
    • Predictive value of derived calcium figures based on the measurement of ionised calcium
    • Gardner MD, Dryburgh FJ, Fyffe JA, Jenkins AS 1981 Predictive value of derived calcium figures based on the measurement of ionised calcium. Ann Clin Biochem 18 (Pt 2):106-109
    • (1981) Ann Clin Biochem , vol.18 , Issue.2 PART , pp. 106-109
    • Gardner, M.D.1    Dryburgh, F.J.2    Fyffe, J.A.3    Jenkins, A.S.4
  • 29
    • 0016721902 scopus 로고
    • Nomogram for derivation of renal threshold phosphate concentration
    • Walton RJ, Bijvoet OL 1975 Nomogram for derivation of renal threshold phosphate concentration. Lancet 2:309-310
    • (1975) Lancet , vol.2 , pp. 309-310
    • Walton, R.J.1    Bijvoet, O.L.2
  • 30
    • 0017104766 scopus 로고
    • Renal cyclic adenosine monophosphate: An accurate index of parathyroid function
    • Drezner MK, Neelon FA, Curtis HB, Lebovitz HE 1976 Renal cyclic adenosine monophosphate: an accurate index of parathyroid function. Metabolism 25:1103-1112
    • (1976) Metabolism , vol.25 , pp. 1103-1112
    • Drezner, M.K.1    Neelon, F.A.2    Curtis, H.B.3    Lebovitz, H.E.4
  • 31
  • 32
    • 0028379864 scopus 로고
    • Radioimmunoassays for IGFs and IGFBPs
    • Blum WF, Breier BH 1994 Radioimmunoassays for IGFs and IGFBPs. Growth Regul 4(Suppl 1):11-19
    • (1994) Growth Regul , vol.4 , Issue.1 SUPPL. , pp. 11-19
    • Blum, W.F.1    Breier, B.H.2
  • 33
    • 0027023957 scopus 로고
    • Chronolab: An interactive software package for chronobiologic time series analysis written for the Macintosh computer
    • Mojon A, Fernandez JR, Hermida RC 1992 Chronolab: an interactive software package for chronobiologic time series analysis written for the Macintosh computer. Chronobiol Int 9:403-412
    • (1992) Chronobiol Int , vol.9 , pp. 403-412
    • Mojon, A.1    Fernandez, J.R.2    Hermida, R.C.3
  • 34
    • 2442680652 scopus 로고    scopus 로고
    • Parathyroid responsiveness to hypocalcemic and hypercalcemic stimuli in adult growth hormone deficiency after growth hormone replacement
    • Ahmad AM, Hopkins MT, Thomas J, Durham BH, Fraser WD, Vora JP 2004 Parathyroid responsiveness to hypocalcemic and hypercalcemic stimuli in adult growth hormone deficiency after growth hormone replacement. Am J Physiol Endocrinol Metab 286:986-993
    • (2004) Am J Physiol Endocrinol Metab , vol.286 , pp. 986-993
    • Ahmad, A.M.1    Hopkins, M.T.2    Thomas, J.3    Durham, B.H.4    Fraser, W.D.5    Vora, J.P.6
  • 35
    • 0028144055 scopus 로고
    • Interactions of growth hormone and parathyroid hormone in renal phosphate, calcium, and calcitriol metabolism and bone remodeling in postmenopausal women
    • Lieberman SA, Holloway L, Marcus R, Hoffman AR 1994 Interactions of growth hormone and parathyroid hormone in renal phosphate, calcium, and calcitriol metabolism and bone remodeling in postmenopausal women. J Bone Miner Res 9:1723-1728
    • (1994) J Bone Miner Res , vol.9 , pp. 1723-1728
    • Lieberman, S.A.1    Holloway, L.2    Marcus, R.3    Hoffman, A.R.4
  • 36
    • 0028988403 scopus 로고
    • Structure-function relationships in the vitamin D endocrine system
    • Bouillon R, Okamura WH, Norman AW 1995 Structure-function relationships in the vitamin D endocrine system. Endocr Rev 16:200-257
    • (1995) Endocr Rev , vol.16 , pp. 200-257
    • Bouillon, R.1    Okamura, W.H.2    Norman, A.W.3
  • 37
    • 0035723672 scopus 로고    scopus 로고
    • Body composition and quality of life in adults with growth hormone deficiency; effects of low-dose growth hormone replacement
    • Oxf
    • Ahmad AM, Hopkins MT, Thomas J, Ibrahim H, Fraser WD, Vora JP 2001 Body composition and quality of life in adults with growth hormone deficiency; effects of low-dose growth hormone replacement. Clin Endocrinol (Oxf) 54:709-717
    • (2001) Clin Endocrinol , vol.54 , pp. 709-717
    • Ahmad, A.M.1    Hopkins, M.T.2    Thomas, J.3    Ibrahim, H.4    Fraser, W.D.5    Vora, J.P.6
  • 38
    • 0024456284 scopus 로고
    • Quality of life of adults with growth hormone deficiency: A controlled study
    • Bjork S, Jonsson B, Westphal O, Levin JE 1989 Quality of life of adults with growth hormone deficiency: a controlled study. Acta Paediatr Scand Suppl 356:55-59; discussion 60:73-74
    • (1989) Acta Paediatr Scand Suppl , vol.356 , pp. 55-59
    • Bjork, S.1    Jonsson, B.2    Westphal, O.3    Levin, J.E.4
  • 40
    • 0024458412 scopus 로고
    • Quality of life assessment before and after growth hormone treatment in adults with growth hormone deficiency
    • McGauley GA 1989 Quality of life assessment before and after growth hormone treatment in adults with growth hormone deficiency. Acta Paediatr Scand Suppl 356:70 -72; discussion 73-74
    • (1989) Acta Paediatr Scand Suppl , vol.356 , pp. 70-72
    • McGauley, G.A.1
  • 41
    • 0028867595 scopus 로고
    • Quality of life in adults with growth hormone (GH) deficiency: Response to treatment with recombinant human GH in a placebo-controlled 21-month trial
    • Burman P, Broman JE, Hetta J, Wiklund I, Erfurth EM, Hagg E, Karlsson FA 1995 Quality of life in adults with growth hormone (GH) deficiency: response to treatment with recombinant human GH in a placebo-controlled 21-month trial. J Clin Endocrinol Metab 80:3585-3590
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3585-3590
    • Burman, P.1    Broman, J.E.2    Hetta, J.3    Wiklund, I.4    Erfurth, E.M.5    Hagg, E.6    Karlsson, F.A.7
  • 42
    • 0029799613 scopus 로고    scopus 로고
    • Molecular basis and clinical application of biological markers of bone turnover
    • Calvo MS, Eyre DR, Gundberg CM 1996 Molecular basis and clinical application of biological markers of bone turnover. Endocr Rev 17:333-368
    • (1996) Endocr Rev , vol.17 , pp. 333-368
    • Calvo, M.S.1    Eyre, D.R.2    Gundberg, C.M.3
  • 44
    • 0026468381 scopus 로고
    • Circadian rhythm and pulsatility of parathyroid hormone secretion in man
    • Oxf
    • Herfarth K, Schmidt-Gayk H, Graf S, Maier A 1992 Circadian rhythm and pulsatility of parathyroid hormone secretion in man. Clin Endocrinol (Oxf) 37:511-519
    • (1992) Clin Endocrinol , vol.37 , pp. 511-519
    • Herfarth, K.1    Schmidt-Gayk, H.2    Graf, S.3    Maier, A.4
  • 45
    • 0026673613 scopus 로고
    • Renal effects of growth hormone: II. Electrolyte homeostasis and body composition
    • Ogle GD, Rosenberg AR, Kainer G 1992 Renal effects of growth hormone: II. Electrolyte homeostasis and body composition. Pediatr Nephrol 6:483-489
    • (1992) Pediatr Nephrol , vol.6 , pp. 483-489
    • Ogle, G.D.1    Rosenberg, A.R.2    Kainer, G.3
  • 46
    • 0029914497 scopus 로고    scopus 로고
    • The effect of low dose recombinant human growth hormone replacement on indices of bone remodelling and bone mineral density in adult growth hormone-deficient adults
    • Weaver JU, Monson JP, Noonan K, Price C, Edwards A, Evans KA, James IT, Cunningham J 1996 The effect of low dose recombinant human growth hormone replacement on indices of bone remodelling and bone mineral density in adult growth hormone-deficient adults. Endocrinol Metab 3:55-61
    • (1996) Endocrinol Metab , vol.3 , pp. 55-61
    • Weaver, J.U.1    Monson, J.P.2    Noonan, K.3    Price, C.4    Edwards, A.5    Evans, K.A.6    James, I.T.7    Cunningham, J.8
  • 47
    • 0031747438 scopus 로고    scopus 로고
    • Effect of long-term treatment with GH on bone metabolism, bone mineral density and bone elasticity in GH-deficient adults
    • Oxf
    • Kann P, Piepkorn B, Schehler B, Andreas J, Lotz J, Prellwitz W, Beyer J 1998 Effect of long-term treatment with GH on bone metabolism, bone mineral density and bone elasticity in GH-deficient adults. Clin Endocrinol (Oxf) 48:561-568
    • (1998) Clin Endocrinol , vol.48 , pp. 561-568
    • Kann, P.1    Piepkorn, B.2    Schehler, B.3    Andreas, J.4    Lotz, J.5    Prellwitz, W.6    Beyer, J.7
  • 48
    • 0029812889 scopus 로고    scopus 로고
    • Two years of growth hormone (GH) treatment increases bone mineral content and density in hypopituitary patients with adult-onset GH deficiency
    • Johannsson G, Rosen T, Bosaeus I, Sjostrom L, Bengtsson BA 1996 Two years of growth hormone (GH) treatment increases bone mineral content and density in hypopituitary patients with adult-onset GH deficiency. J Clin Endocrinol Metab 81:2865-2873
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2865-2873
    • Johannsson, G.1    Rosen, T.2    Bosaeus, I.3    Sjostrom, L.4    Bengtsson, B.A.5
  • 49
    • 0035999443 scopus 로고    scopus 로고
    • The effects of growth hormone replacement therapy on bone metabolism in adult-onset growth hormone deficiency: A 2-year open randomized controlled multicenter trial
    • Bex M, Abs R, Maiter D, Beckers A, Lamberigts G, Bouillon R 2002 The effects of growth hormone replacement therapy on bone metabolism in adult-onset growth hormone deficiency: a 2-year open randomized controlled multicenter trial. J Bone Miner Res 17:1081-1094
    • (2002) J Bone Miner Res , vol.17 , pp. 1081-1094
    • Bex, M.1    Abs, R.2    Maiter, D.3    Beckers, A.4    Lamberigts, G.5    Bouillon, R.6
  • 50
    • 0034527637 scopus 로고    scopus 로고
    • Growth hormone replacement therapy improves body composition and increases bone metabolism in elderly patients with pituitary disease
    • Fernholm R, Bramnert M, Hagg E, Hilding A, Baylink DJ, Mohan S, Thoren M 2000 Growth hormone replacement therapy improves body composition and increases bone metabolism in elderly patients with pituitary disease. J Clin Endocrinol Metab 85:4104-4112
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4104-4112
    • Fernholm, R.1    Bramnert, M.2    Hagg, E.3    Hilding, A.4    Baylink, D.J.5    Mohan, S.6    Thoren, M.7
  • 51
    • 0029830219 scopus 로고    scopus 로고
    • Body composition in growth hormone deficient adults over the age of 60 years
    • Oxf
    • Toogood AA, Adams JE, O'Neill PA, Shalet SM 1996 Body composition in growth hormone deficient adults over the age of 60 years. Clin Endocrinol (Oxf) 45:399-405
    • (1996) Clin Endocrinol , vol.45 , pp. 399-405
    • Toogood, A.A.1    Adams, J.E.2    O'Neill, P.A.3    Shalet, S.M.4
  • 52
    • 0031800687 scopus 로고    scopus 로고
    • The diagnosis of severe growth hormone deficiency in elderly patients with hypothalamic-pituitary disease
    • Oxf
    • Toogood AA, Jones J, O'Neill PA, Thorner MO, Shalet SM 1998 The diagnosis of severe growth hormone deficiency in elderly patients with hypothalamic-pituitary disease. Clin Endocrinol (Oxf) 48:569-576
    • (1998) Clin Endocrinol , vol.48 , pp. 569-576
    • Toogood, A.A.1    Jones, J.2    O'Neill, P.A.3    Thorner, M.O.4    Shalet, S.M.5
  • 53
    • 1642407891 scopus 로고    scopus 로고
    • Low bone mass is an infrequent feature of the adult growth hormone deficiency syndrome in middle-age adults and the elderly
    • Murray RD, Columb B, Adams JE, Shalet SM 2004 Low bone mass is an infrequent feature of the adult growth hormone deficiency syndrome in middle-age adults and the elderly. J Clin Endocrinol Metab 89:1124-1130
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1124-1130
    • Murray, R.D.1    Columb, B.2    Adams, J.E.3    Shalet, S.M.4
  • 54
    • 0033829206 scopus 로고    scopus 로고
    • Growth hormone deficiency and replacement in elderly hypopituitary adults: KIMS Study Group and the KIMS International Board. Pharmacia and Upjohn International Metabolic Database
    • Oxf
    • Monson JP, Abs R, Bengtsson BA, Bennmarker H, Feldt-Rasmussen U, Hernberg-Stahl E, Thoren M, Westberg B, Wilton P, Wuster C 2000 Growth hormone deficiency and replacement in elderly hypopituitary adults: KIMS Study Group and the KIMS International Board. Pharmacia and Upjohn International Metabolic Database. Clin Endocrinol (Oxf) 53:281-289
    • (2000) Clin Endocrinol , vol.53 , pp. 281-289
    • Monson, J.P.1    Abs, R.2    Bengtsson, B.A.3    Bennmarker, H.4    Feldt-Rasmussen, U.5    Hernberg-Stahl, E.6    Thoren, M.7    Westberg, B.8    Wilton, P.9    Wuster, C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.