Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease

Neuroscience Letters

Volumn 382, Issue 3, 2005, Pages 221-226

  Pritchard, Antonia ^a   Harris, Judith ^a   Pritchard, Colin W ^b   St Clair, David ^c   Lemmon, Helen ^c   Lambert, Jean Charles ^d   Chartier Harlin, Marie Christine ^d   Hayes, Angela ^e   Thaker, Uma ^e   Iwatsubo, Takeshi ^f   Mann, David M A ^e   Lendon, Corinne ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b ROYAL CORNWALL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

^d INSTITUT PASTEUR DE LILLE   (France)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

Alzheimer's disease; Association study; Brain pathology; LRP1; Meta analysis

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; LOW DENSITY LIPOPROTEIN RECEPTOR; TAU PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; CELL ACTIVITY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN TISSUE; MALE; MICROGLIA; ONSET AGE; PHENOTYPE; PRIORITY JOURNAL; RISK FACTOR; UNITED KINGDOM;

AGE OF ONSET; AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; APOLIPOPROTEINS E; BRAIN; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMMUNOHISTOCHEMISTRY; LDL-RECEPTOR RELATED PROTEIN 1; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 21144445954     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.03.016     Document Type: Article

References (37)

1. L. Baum, L. Chen, H.K. Ng, Y.S. Chan, Y.T. Mak, J. Woo, H.F. Chiu, and C.P. Pang Low density lipoprotein receptor related protein gene exon 3 polymorphism association with Alzheimer's disease in Chinese Neurosci. Lett. 247 1998 33 36
2. U. Beffert, C. Arguin, and J. Poirier The polymorphism in exon 3 of the low density lipoprotein receptor-related protein gene is weakly associated with Alzheimer's disease Neurosci. Lett. 259 1999 29 32
3. U. Beisiegel, W. Weber, G. Ihrke, J. Herz, and K. Stanley The LDL-receptor-related protein LRP, is an apolipoprotein E-binding protein Nature 341 1989 162 164
4. L. Bertram, D. Blacker, A. Crystal, K. Mullin, D. Keeney, J. Jones, S. Basu, S. Yhu, S. Guenette, M. Mclnnis, R. Go, and R. Tanzi Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family based methodologies Exp. Gerontol. 35 2000 1353 1361
5. S. Bi, Y. Zhang, J. Wu, D. Wang, and Q. Zhao Association between low-density lipoprotein receptor-related protein gene, butyrylcholinesterase gene and Alzheimer' s disease in Chinese Chin. Med. Sci. J. 16 2001 71 75
6. M. Bullido, P. Guallar-Castillion, M. Artiga, M. Ramos, I. Sastre, J. Aldudo, A. Frank, F. Coria, F. Rodriguez-Artalejo, and F. Valdivieso Alzheimer's risk associated with human apolipoprotein E, alpha-2 macroglobulin and lipoprotein receptor related protein polymorphisms: absence of genetic interactions and moduclation by gender Neurosci. Lett. 289 2000 213 216
7. M. Egger, G.D. Smith, and A. Phillips Meta-analysis: principles and procedures Br. Med. J. 315 1997 1533 1537
8. L.A. Farrer, L.A. Cupples, J.L. Haines, B. Hyman, W.A. Kukull, R. Mayeux, R.H. Myers, M.A. Pericak-Vance, N. Risch, and C.M. van Duijn Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium J. Am. Med. Assoc. 278 1997 1349 1356
9. E.K. Green, J.M. Harris, H. Lemmon, J.C. Lambert, M.C. Chartier-Harlin, D. St Clair, D.M. Mann, T. Iwatsubo, and C.L. Lendon Are interleukin-1 gene polymorphisms risk factors or disease modifiers in AD Neurology 58 2002 1566 1568
10. Y. Hatanaka, K. Kamino, K. Fukuo, N. Mitsuda, Y. Nishiwaki-Ueda, N. Sato, T. Satoh, H. Yamamoto, H. Yoneda, M. Imagawa, T. Miki, S. Ohta, and T. Ogihara Low density lipoprotein receptor-related protein gene polymorphisms and risk for late-onset Alzheimer's disease in a Japanese population Clin. Genet. 58 2000 319 323
11. A. Hayes, U. Thaker, T. Iwatsubo, S. Pickering-Brown, and D.M. Mann Pathological relationships between microglial cell activity and tau and amyloid beta protein in patients with Alzheimer's disease Neurosci. Lett. 331 2002 171 174
12. L.V. Hedges, and I. Olkin Statistical Methods in Meta-Analysis 1985 Academic Press New York
13. J. Herz, and D. Strickland LRP: a multifunctional scavenger and signaling receptor J. Clin. Investig. 108 2001 779 784
14. E. Hollenbach, S. Ackermann, B.T. Hyman, and G.W. Rebeck Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease Neurology 50 1998 1905 1907
15. C.J. Hu, S.M. Sung, H.C. Liu, W.C. Hsu, L.S. Lee, C.C. Lee, C.H. Tsai, and J.G. Chang Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan J. Neurol. Sci. 181 2000 127 131
16. T. Iwatsubo, A. Odaka, N. Suzuki, H. Mizusawa, N. Nukina, and Y. Ihara Visualisation of A beta 42(43) and A beta 40 in senile plaques with end specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43) Neurone 13 1994 45 53
17. I. Kamboh, R. Ferrell, and S. DeKosky Genetic association studies between Alzheimer's disease and two polymorphisms in the low density lipoprotein gene Neurosci. Lett. 224 1998 65 68
18. M.I. Kamboh Molecular genetics of late-onset Alzheimer's disease Ann. Hum. Genet. 68 2004 381 404
19. D. Kang, T. Saitoh, X. Chen, Y. Xia, E. Masliah, L. Hansen, R. Thomas, L. Thal, and R. Katzman Genetic association of the low density lipoprotein receptor related protein gene (LRP), an apolipoprotein E receptor, with late onset Alzheimer's disease Neurology 49 1997 56 61
20. D.E. Kang, T. Saitoh, X. Chen, Y. Xia, E. Masliah, L.A. Hansen, R.G. Thomas, L.J. Thal, and R. Katzman Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease Neurology 49 1997 56 61
21. H. Kolsch, U. Ptok, I. Mohamed, S. Schmitz, M.L. Rao, W. Maier, and R. Heun Association of the C766T polymorphism of the low-density lipoprotein receptor-related protein gene with Alzheimer's disease Am. J. Med. Genet. 121B 2003 128 130
22. M. Kounnas, R. Moir, W. Rebeck, A. Bush, W. Argraves, R. Tanzi, B. Hyman, and D. Strickland LDL receptor-related protein, a multifunctional APOE receptor, binds secreted β-amyloid precursor protein and mediates its degradation Cell 82 1995 331 340
23. J.C. Lambert, F. Wavrant De-Vrieze, P. Amouyel, and M.C. Chartier-Harlin Association at LRP gene locus with sporadic late-onset Alzheimer's disease Lancet 351 1998 1787 1788
24. C.L. Lendon, C.J. Talbot, N.J. Craddock, S.W. Han, M. Wragg, J.C. Morris, and A.M. Goate Genetic association studies between dementia of the Alzheimer's type and three receptors for apolipoprotein E in a Caucasian population Neurosci. Lett. 222 1997 187 190
25. E. Luedecking-Zimmer, S. DeKosky, R. Nebes, and I. Kamboh Association of the 3′UTR transcription factor LBP-1c/CP2/LSF polymorphism with late-onset Alzheimer's disease Am. J. Med. Genet. (Neuropsychiatr. Genet.) 117B 2003 114 117
26. S.P. Mcllroy, K.B. Dynan, D.J. Vahidassr, J.T. Lawson, C.C. Patterson, and P. Passmore Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland Am. J. Med. Genet. 105 2001 502 506
27. F. Panza, A. D'Introno, A. Colacicco, C. Capurso, A. Basile, S. Capurso, A. Capurso, and V. Solfrizzi Regional European differences in allele and genotype frequencies of low density lipoprotein receptor related protein 1 polymorphism in Alzheimer's disease Am. J. Med. Genet. (Neuropsychiatr. Genet.) 126B 2004 69 73
28. J. Prince, L. Feuk, S. Sawyer, J. Gottfries, A. Ricksten, K. Nagga, N. Bogdanovic, K. Blennow, and A. Brookes Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease Eur. J. Hum. Genet. 9 2001 437 444
29. M. Sanchez-Guerra, O. Combarros, J. Infante, J. Llorca, J. Berciano, A. Fontalba, J. Fernandez-Luna, N. Pena, and C. Fernandez-Viadero Case-control and meta analysis of low density lipoprotein receptor related protein gene exon 3 polymorphism in Alzheimer's disease Neurosci. Lett. 316 2001 17 20
30. M. Shibata, S. Yamada, S. Kumar, M. Calero, J. Bading, B. Frangione, D. Holtzman, C. Miller, D. Strickland, J. Ghiso, and B. Zlokovic Clearance of Alzheimer's amyloid ss(1-40) peptide from the brain by LDL receptor-related protein-1 at the blood brain barrier J. Clin. Investig. 106 2000 1489 1499
31. I. Tooyama, T. Kawamata, H. Akiyama, H. Kimura, S. Moestrup, J. Gliemann, A. Matsuo, and P. McGeer Subcellular localisation of the low density lipoprotein receptor-related protein (alpha-2-macroglobulin receptor) in human brain Brain Res. 691 1995 235 238
32. F. Van Leuven, E. Thiry, L. Stas, and B. Nelissen Analysis of the human LRP API gene coding for the lipoprotein receptor associated protein: identification of 22 polymorphisms and one mutation Genomics 52 1998 145 151
33. E. Van Uden, G. Carlson, P. St George-Hyslop, D. Westaway, R.M.M. Orlando, E. Rockenstein, and E. Masliah Aberrant presenillin-1 expression downregulates LDL receptor related protein (LRP): is LRP central to Alzheimer's disease pathogenesis Mol. Cell. Neurosci. 14 1999 129 140
34. P. Verpillat, S. Bouley, D. Campion, D. Hannequin, B. Dubois, S. Belliard, M. Puel, C. Thomas-Anterion, Y. Agid, A. Brice, and F. Clerget-Darpoux Use of haplotype information to test involvement of the LRP gene in Alzheimer's disease in the French population Eur. J. Hum. Genet. 9 2001 464 468
35. F. Wavrant De-Vrieze, J.C. Lambert, L. Stas, R. Crook, D. Cottel, F. Pasquier, B. Frigard, M. Lambrechts, E. Thiry, P. Amouyel, J. Tur, M.C. Chartier-Harlin, J. Hardy, and F. Van Leuven Association between coding variability in the LRP gene and the risk of Alzheimer's disease Hum. Genet. 104 1999 432 434
36. B. Wolf, M. Lopes, S. VandenBerg, and S. Gonias Characterisation and immunohistochemical localisation of alpha 2-macroglobulin receptor (low density lipoprotein receptor-related protein) in human brain Am. J. Pathol. 141 1992 37 42
37. R. Woodward, A.B. Singleton, A.M. Gibson, J.A. Edwardson, and C.M. Morris LRP gene and late-onset Alzheimer's disease Lancet 352 1998 239 240 Alzforum website: http://www, alzforum. org/res/com/gen/alzgene/chromo.asp?c=12