-
1
-
-
1242263295
-
From monoamines to genomic targets: A paradigm shift for drug discovery in depression
-
Wong, M. L. & Licinio, J. From monoamines to genomic targets: a paradigm shift for drug discovery in depression. Nature Rev. Drug Discov. 3, 136-151 (2004).
-
(2004)
Nature Rev. Drug Discov.
, vol.3
, pp. 136-151
-
-
Wong, M.L.1
Licinio, J.2
-
2
-
-
4644271084
-
Magic shotguns versus magic bullets: Selectively non-selective drugs for mood disorders and schizophrenia
-
Roth, B. L., Sheffler, D. J. & Kroeze, W. K. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nature Rev. Drug Discov. 3, 353-359 (2004).
-
(2004)
Nature Rev. Drug Discov.
, vol.3
, pp. 353-359
-
-
Roth, B.L.1
Sheffler, D.J.2
Kroeze, W.K.3
-
3
-
-
0030858270
-
Limbic-cortical dysregulation: A proposed model of depression
-
Mayberg, H. S. Limbic-cortical dysregulation: a proposed model of depression. J. Neuropsychiatry Clin. Neurosci. 9, 471-481 (1997).
-
(1997)
J. Neuropsychiatry Clin. Neurosci.
, vol.9
, pp. 471-481
-
-
Mayberg, H.S.1
-
4
-
-
0347415656
-
Modulation of cortical-limbic pathways in major depression: Treatment-specific effects of cognitive behavior therapy
-
Goldapple, K. et al. Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy. Arch. Gen. Psychiatry 61, 34-41 (2004).
-
(2004)
Arch. Gen. Psychiatry
, vol.61
, pp. 34-41
-
-
Goldapple, K.1
-
5
-
-
0346365559
-
Personality influences limbic-cortical interactions during sad mood induction
-
Keightley, M. L. et al. Personality influences limbic-cortical interactions during sad mood induction. Neuroimage 20, 2031-2039 (2003).
-
(2003)
Neuroimage
, vol.20
, pp. 2031-2039
-
-
Keightley, M.L.1
-
6
-
-
0028264040
-
Paralimbic hypoperfusion in unipolar depression
-
Mayberg, H. S., Lewis, P. J., Regenold, W. & Wagner, H. N. Jr. Paralimbic hypoperfusion in unipolar depression. J. Nucl. Med. 35, 929-934 (1994).
-
(1994)
J. Nucl. Med.
, vol.35
, pp. 929-934
-
-
Mayberg, H.S.1
Lewis, P.J.2
Regenold, W.3
Wagner Jr., H.N.4
-
7
-
-
1942542433
-
Limbic-frontal circuitry in major depression: A path modeling metanalysis
-
Seminowicz, D. A. et al. Limbic-frontal circuitry in major depression: a path modeling metanalysis. Neuroimage 22, 409-418 (2004).
-
(2004)
Neuroimage
, vol.22
, pp. 409-418
-
-
Seminowicz, D.A.1
-
8
-
-
14644402983
-
Deep brain stimulation for treatment-resistant depression
-
Mayberg, H. S. et al. Deep brain stimulation for treatment-resistant depression. Neuron 45, 651-660 (2005).
-
(2005)
Neuron
, vol.45
, pp. 651-660
-
-
Mayberg, H.S.1
-
9
-
-
0038147541
-
Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression
-
Manji, H. K. et al. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biol. Psychiatry 53, 707-742 (2003).
-
(2003)
Biol. Psychiatry
, vol.53
, pp. 707-742
-
-
Manji, H.K.1
-
10
-
-
0042528720
-
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
-
Santarelli, L. et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301, 805-809 (2003).
-
(2003)
Science
, vol.301
, pp. 805-809
-
-
Santarelli, L.1
-
11
-
-
0038713946
-
Separation of anxiety and depressive disorders: Blind alley in psychopharmacology and classification of disease
-
Shorter, E. & Tyrer, P. Separation of anxiety and depressive disorders: blind alley in psychopharmacology and classification of disease. BMJ 327, 158-160 (2003).
-
(2003)
BMJ
, vol.327
, pp. 158-160
-
-
Shorter, E.1
Tyrer, P.2
-
12
-
-
0037624040
-
Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
-
Caspi, A. et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301, 386-389 (2003).
-
(2003)
Science
, vol.301
, pp. 386-389
-
-
Caspi, A.1
-
13
-
-
0032946104
-
Changes in personality traits during treatment with sertraline or citalopram
-
Ekselius, L. & Von Knorring, L. Changes in personality traits during treatment with sertraline or citalopram. Br. J. Psychiatry 174, 444-448 (1999).
-
(1999)
Br. J. Psychiatry
, vol.174
, pp. 444-448
-
-
Ekselius, L.1
Von Knorring, L.2
-
14
-
-
84970865754
-
Suicide and antidepressants
-
Edwards, J. G. Suicide and antidepressants. BMJ 310, 205-206 (1995).
-
(1995)
BMJ
, vol.310
, pp. 205-206
-
-
Edwards, J.G.1
-
15
-
-
0033061974
-
Suicide in the course of the treatment of depression
-
Healy, D., Langmaak, C. & Savage, M. Suicide in the course of the treatment of depression. J. Psychopharmacol. 13, 94-99 (1999).
-
(1999)
J. Psychopharmacol.
, vol.1
, pp. 94-99
-
-
Healy, D.1
Langmaak, C.2
Savage, M.3
-
17
-
-
0036180024
-
Atypical antipsychotic-induced diabetes mellitus: How strong is the evidence?
-
Henderson, D. C. Atypical antipsychotic-induced diabetes mellitus: how strong is the evidence? CNS Drugs 16, 77-89 (2002).
-
(2002)
CNS Drugs
, vol.16
, pp. 77-89
-
-
Henderson, D.C.1
-
18
-
-
20844444633
-
Introduction: Cardiovascular and metabolic risks associated with schizophrenia and antipsychotic drug treatment
-
Meltzer, H. Y. Introduction: cardiovascular and metabolic risks associated with schizophrenia and antipsychotic drug treatment. J. Clin. Psychiatry 63, 3-4 (2002).
-
(2002)
J. Clin. Psychiatry
, vol.63
, pp. 3-4
-
-
Meltzer, H.Y.1
-
19
-
-
0141802426
-
Risk of cardiovascular disease and sudden death in schizophrenia
-
Davidson, M. Risk of cardiovascular disease and sudden death in schizophrenia. J. Clin. Psychiatry 63 (Suppl. 9), 5-11 (2002).
-
(2002)
J. Clin. Psychiatry
, vol.63
, Issue.SUPPL. 9
, pp. 5-11
-
-
Davidson, M.1
-
20
-
-
0038816591
-
Mechanisms and risks of electrocardiographic QT interval prolongation when using antipsychotic drugs
-
Vieweg, W. V. Mechanisms and risks of electrocardiographic QT interval prolongation when using antipsychotic drugs. J. Clin. Psychiatry 63 (Suppl. 9), 18-24 (2002).
-
(2002)
J. Clin. Psychiatry
, vol.63
, Issue.SUPPL. 9
, pp. 18-24
-
-
Vieweg, W.V.1
-
21
-
-
11344282078
-
Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression
-
(in the press)
-
Zhang, X. et al. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron (in the press).
-
Neuron.
-
-
Zhang, X.1
-
22
-
-
8544249878
-
The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology
-
Pezawas, L. et al. The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. J. Neurosci. 24, 10099-10102 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 10099-10102
-
-
Pezawas, L.1
-
23
-
-
0037406832
-
Epigenetic sources of behavioral differences in mice
-
Francis, D. D., Szegda, K., Campbell, G., Martin, W. D. & Insel, T. R. Epigenetic sources of behavioral differences in mice. Nature Neurosci. 6, 445-446 (2003).
-
(2003)
Nature Neurosci.
, vol.6
, pp. 445-446
-
-
Francis, D.D.1
Szegda, K.2
Campbell, G.3
Martin, W.D.4
Insel, T.R.5
-
24
-
-
0033047097
-
Psychosocial adversity and child psychopathology
-
Rutter, M. L. Psychosocial adversity and child psychopathology. Br. J. Psychiatry 174, 480-493 (1999).
-
(1999)
Br. J. Psychiatry
, vol.174
, pp. 480-493
-
-
Rutter, M.L.1
-
25
-
-
0033795496
-
Childhood sexual abuse and adult psychiatric and substance use disorders in women: An epidemiological and cotwin control analysis
-
Kendler, K. S. et al. Childhood sexual abuse and adult psychiatric and substance use disorders in women: an epidemiological and cotwin control analysis. Arch. Gen. Psychiatry 57, 953-959 (2000).
-
(2000)
Arch. Gen. Psychiatry
, vol.57
, pp. 953-959
-
-
Kendler, K.S.1
-
26
-
-
0036893094
-
Mss4 gene is up-regulated in rat brain after chronic treatment with antidepressant and down-regulated when rats are anhedonic
-
Andriamampandry, C. et al. Mss4 gene is up-regulated in rat brain after chronic treatment with antidepressant and down-regulated when rats are anhedonic. Mol. Pharmacol. 62, 1332-1338 (2002).
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 1332-1338
-
-
Andriamampandry, C.1
-
27
-
-
0041421151
-
Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro
-
Gunther, E. C., Stone, D. J., Gerwien, R. W., Bento, P. & Heyes, M. P. Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro. Proc. Natl Acad. Sci. USA 100, 9608-9613 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 9608-9613
-
-
Gunther, E.C.1
Stone, D.J.2
Gerwien, R.W.3
Bento, P.4
Heyes, M.P.5
-
28
-
-
0036907810
-
Anxiety associated with comorbid depression
-
Moller, H. J. Anxiety associated with comorbid depression. J. Clin. Psychiatry 63 (Suppl. 14), 22-26 (2002).
-
(2002)
J. Clin. Psychiatry
, vol.63
, Issue.SUPPL. 14
, pp. 22-26
-
-
Moller, H.J.1
-
29
-
-
0031471239
-
Fear conditioning induces associative long-term potentiation in the amygdala
-
Rogan, M. T., Staubli, U. V. & LeDoux, J. E. Fear conditioning induces associative long-term potentiation in the amygdala. Nature 390, 604-607 (1997).
-
(1997)
Nature
, vol.390
, pp. 604-607
-
-
Rogan, M.T.1
Staubli, U.V.2
LeDoux, J.E.3
-
30
-
-
0031441897
-
Fear conditioning induces a lasting potentiation of synaptic currents in vitro
-
McKernan, M. G. & Shinnick-Gallagher, P. Fear conditioning induces a lasting potentiation of synaptic currents in vitro. Nature 390, 607-611 (1997).
-
(1997)
Nature
, vol.390
, pp. 607-611
-
-
McKernan, M.G.1
Shinnick-Gallagher, P.2
-
31
-
-
0030741609
-
Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease
-
Convit, A. et al. Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease. Neurobiol. Aging 18, 131-138 (1997).
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 131-138
-
-
Convit, A.1
-
32
-
-
0028427915
-
Hippocampal formation size in normal human aging: A correlate of delayed secondary memory performance
-
Golomb, J. et al. Hippocampal formation size in normal human aging: a correlate of delayed secondary memory performance. Learn. Mem. 1, 45-54 (1994).
-
(1994)
Learn. Mem.
, vol.1
, pp. 45-54
-
-
Golomb, J.1
-
33
-
-
0029044351
-
MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder
-
Bremner, J. D. et al. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am. J. Psychiatry 152, 973-981 (1995).
-
(1995)
Am. J. Psychiatry
, vol.152
, pp. 973-981
-
-
Bremner, J.D.1
-
34
-
-
0030560641
-
Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder
-
Gurvits, T. V. et al. Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder. Biol. Psychiatry 40, 1091-1099 (1996).
-
(1996)
Biol. Psychiatry
, vol.40
, pp. 1091-1099
-
-
Gurvits, T.V.1
-
35
-
-
0029862949
-
Hippocampal atrophy in recurrent major depression
-
Sheline, Y. I., Wang, P. W., Gado, M. H., Csernansky, J. G. & Vannier, M. W. Hippocampal atrophy in recurrent major depression. Proc. Natl Acad. Sci. USA 93, 3908-3913 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3908-3913
-
-
Sheline, Y.I.1
Wang, P.W.2
Gado, M.H.3
Csernansky, J.G.4
Vannier, M.W.5
-
36
-
-
0033564043
-
Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression
-
Sheline, Y. I., Sanghavi, M., Mintun, M. A. & Gado, M. H. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. J. Neurosci. 19, 5034-5043 (1999).
-
(1999)
J. Neurosci.
, vol.19
, pp. 5034-5043
-
-
Sheline, Y.I.1
Sanghavi, M.2
Mintun, M.A.3
Gado, M.H.4
-
37
-
-
0033135554
-
Cell atrophy and loss in major depression
-
Duman, R. S. & Charney D. S. Cell atrophy and loss in major depression. Biol. Psychiatry 45, 1083-1084 (1999).
-
(1999)
Biol. Psychiatry
, vol.45
, pp. 1083-1084
-
-
Duman, R.S.1
Charney, D.S.2
-
38
-
-
0036593119
-
The stressed hippocampus, synaptic plasticity and lost memories
-
Kim, J. J. & Diamond, D. M. The stressed hippocampus, synaptic plasticity and lost memories. Nature Rev. Neurosci. 3, 453-462 (2002).
-
(2002)
Nature Rev. Neurosci.
, vol.3
, pp. 453-462
-
-
Kim, J.J.1
Diamond, D.M.2
-
39
-
-
0942279687
-
Acute Stress-induced Changes in Hippocampal/Prefrontal Circuits in Rats: Effects of Antidepressants
-
Rocher, C., Spedding, M., Munoz, C. & Jay, T. M. Acute Stress-induced Changes in Hippocampal/Prefrontal Circuits in Rats: Effects of Antidepressants. Cereb. Cortex 14, 224-229 (2004).
-
(2004)
Cereb. Cortex
, vol.14
, pp. 224-229
-
-
Rocher, C.1
Spedding, M.2
Munoz, C.3
Jay, T.M.4
-
40
-
-
0023877370
-
Effect of neonatal handling on age-related impairments associated with the hippocampus
-
Meaney, M. J., Aitken, D. H., van Berkel, C., Bhatnagar, S. & Sapolsky, R. M. Effect of neonatal handling on age-related impairments associated with the hippocampus. Science 239, 766-768 (1988).
-
(1988)
Science
, vol.239
, pp. 766-768
-
-
Meaney, M.J.1
Aitken, D.H.2
van Berkel, C.3
Bhatnagar, S.4
Sapolsky, R.M.5
-
41
-
-
0036627586
-
The role of prenatal stress in the etiology of developmental behavioural disorders
-
Kofman, O. The role of prenatal stress in the etiology of developmental behavioural disorders. Neurosci. Biobehav. Rev. 26, 457-470 (2002).
-
(2002)
Neurosci. Biobehav. Rev.
, vol.6
, pp. 457-470
-
-
Kofman, O.1
-
42
-
-
0036895697
-
Childhood trauma associated with smaller hippocampal volume in women with major depression
-
Vythilingam, M. et al. Childhood trauma associated with smaller hippocampal volume in women with major depression. Am. J. Psychiatry 159, 2072-2080 (2002).
-
(2002)
Am. J. Psychiatry
, vol.59
, pp. 2072-2080
-
-
Vythilingam, M.1
-
43
-
-
0036896048
-
Relationship between distressing cancer-related recollections and hippocampal volume in cancer survivors
-
Nakano, T. et al. Relationship between distressing cancer-related recollections and hippocampal volume in cancer survivors. Am. J. Psychiatry 159, 2087-2093 (2002).
-
(2002)
Am. J. Psychiatry
, vol.159
, pp. 2087-2093
-
-
Nakano, T.1
-
44
-
-
9244248151
-
Fear learning transiently impairs hippocampal cell proliferation
-
Pham, K., McEwen, B. S., LeDoux, J. E. & Nader, K. Fear learning transiently impairs hippocampal cell proliferation. Neuroscience 130, 17-24 (2005).
-
(2005)
Neuroscience
, vol.130
, pp. 17-24
-
-
Pham, K.1
McEwen, B.S.2
LeDoux, J.E.3
Nader, K.4
-
45
-
-
0027476024
-
A synaptic model of memory: Long-term potentiation in the hippocampus
-
Bliss, T. V. & Collingridge, G. L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39 (1993).
-
(1993)
Nature
, vol.361
, pp. 31-39
-
-
Bliss, T.V.1
Collingridge, G.L.2
-
46
-
-
0034042406
-
Synaptic plasticity and memory: An evaluation of the hypothesis
-
Martin, S. J., Grimwood, P. D. & Morris, R. G. Synaptic plasticity and memory: an evaluation of the hypothesis. Annu. Rev. Neurosci. 23, 649-711 (2000).
-
(2000)
Annu. Rev. Neurosci.
, vol.23
, pp. 649-711
-
-
Martin, S.J.1
Grimwood, P.D.2
Morris, R.G.3
-
47
-
-
9644265305
-
Bidirectional activity-dependent morphological plasticity in hippocampal neurons
-
Nagerl, U. V., Eberhorn, N., Cambridge, S. B. & Bonhoeffer, T. Bidirectional activity-dependent morphological plasticity in hippocampal neurons. Neuron 44, 759-767 (2004).
-
(2004)
Neuron
, vol.44
, pp. 759-767
-
-
Nagerl, U.V.1
Eberhorn, N.2
Cambridge, S.B.3
Bonhoeffer, T.4
-
48
-
-
9644278075
-
Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses
-
Zhou, Q., Homma, K. J. & Poo, M. M. Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses. Neuron 44, 749-757 (2004).
-
(2004)
Neuron
, vol.44
, pp. 749-757
-
-
Zhou, Q.1
Homma, K.J.2
Poo, M.M.3
-
49
-
-
0033761566
-
Learning-induced LTP in neocortex
-
Rioult-Pedotti, M. S., Friedman, D. & Donoghue, J. P. Learning-induced LTP in neocortex. Science 290, 533-536 (2000).
-
(2000)
Science
, vol.290
, pp. 533-536
-
-
Rioult-Pedotti, M.S.1
Friedman, D.2
Donoghue, J.P.3
-
50
-
-
0037061693
-
Formation of dendritic spines with GABAergic synapses induced by whisker stimulation in adult mice
-
Knott, G. W., Quairiaux, C., Genoud, C. & Welker, E. Formation of dendritic spines with GABAergic synapses induced by whisker stimulation in adult mice. Neuron 34, 265-273 (2002).
-
(2002)
Neuron
, vol.34
, pp. 265-273
-
-
Knott, G.W.1
Quairiaux, C.2
Genoud, C.3
Welker, E.4
-
51
-
-
0036122267
-
The role of synaptic morphology in neural plasticity: Structural interactions underlying synaptic power
-
Marrone, D. F. & Petit, T. L. The role of synaptic morphology in neural plasticity: structural interactions underlying synaptic power. Brain Res. Brain Res. Rev. 38, 291-308 (2002).
-
(2002)
Brain Res. Brain Res. Rev.
, vol.38
, pp. 291-308
-
-
Marrone, D.F.1
Petit, T.L.2
-
52
-
-
0036325981
-
Neuroplasticity in old age: Sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment
-
Kempermann, G., Gast, D. & Gage, F. H. Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Ann. Neurol. 52, 135-143 (2002).
-
(2002)
Ann. Neurol.
, vol.52
, pp. 135-143
-
-
Kempermann, G.1
Gast, D.2
Gage, F.H.3
-
53
-
-
84979726329
-
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis
-
Pluchino, S. et al. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature 422, 688-694 (2003).
-
(2003)
Nature
, vol.422
, pp. 688-694
-
-
Pluchino, S.1
-
54
-
-
0037417901
-
Transplanted bone marrow generates new neurons in human brains
-
Mezey, E. et al. Transplanted bone marrow generates new neurons in human brains. Proc. Natl Acad. Sci. USA 100, 1364-1369 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1364-1369
-
-
Mezey, E.1
-
55
-
-
0037304064
-
Brain plasticity and pathology in psychiatric disease: Sites of action for potential therapy
-
Spedding, M., Neau, I. & Horsing, L. Brain plasticity and pathology in psychiatric disease: sites of action for potential therapy. Curr. Opin. Pharmacol. 3, 33-40 (2003).
-
(2003)
Curr. Opin. Pharmacol.
, vol.3
, pp. 33-40
-
-
Spedding, M.1
Neau, I.2
Horsing, L.3
-
57
-
-
0346461651
-
Electrophysiological interactions between striatal glutamatergic and dopaminergic systems
-
West, A. R., Floresco, S. B., Charara, A., Rosenkranz, J. A. &Grace, A. A. Electrophysiological interactions between striatal glutamatergic and dopaminergic systems. Ann. NY Acad. Sci. 1003, 53-74 (2003).
-
(2003)
Ann. NY Acad. Sci.
, vol.1003
, pp. 53-74
-
-
West, A.R.1
Floresco, S.B.2
Charara, A.3
Rosenkranz, J.A.4
Grace, A.A.5
-
58
-
-
0034668879
-
Essential role of D1 but not D2 receptors in the NMDA receptor-dependent long-term potentiation at hippocampal-prefrontal cortex synapses in vivo
-
Gurden, H., Takita, M. & Jay, T. M. Essential role of D1 but not D2 receptors in the NMDA receptor-dependent long-term potentiation at hippocampal-prefrontal cortex synapses in vivo. J. Neurosci. 20, RC106 (2000).
-
(2000)
J. Neurosci.
, vol.20
-
-
Gurden, H.1
Takita, M.2
Jay, T.M.3
-
59
-
-
0034061495
-
Reward processing in primate orbitofrontal cortex and basal ganglia
-
Schultz, W., Tremblay, L. & Hollerman, J. R. Reward processing in primate orbitofrontal cortex and basal ganglia. Cereb. Cortex 10, 272-284 (2000).
-
(2000)
Cereb. Cortex
, vol.10
, pp. 272-284
-
-
Schultz, W.1
Tremblay, L.2
Hollerman, J.R.3
-
60
-
-
0030851206
-
A molecular and cellular theory of depression
-
Duman, R. S., Heninger, G. R. & Nestler, E. J. A molecular and cellular theory of depression. Arch. Gen. Psychiatry 54, 597-606 (1997).
-
(1997)
Arch. Gen. Psychiatry
, vol.54
, pp. 597-606
-
-
Duman, R.S.1
Heninger, G.R.2
Nestler, E.J.3
-
61
-
-
0032983086
-
Antidepressants for the new millennium
-
Skolnick, P. Antidepressants for the new millennium. Eur. J. Pharmacol. 375, 31-40 (1999).
-
(1999)
Eur. J. Pharmacol.
, vol.375
, pp. 31-40
-
-
Skolnick, P.1
-
62
-
-
0031439983
-
Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons
-
Tongiorgi, E., Righi, M. & Cattaneo, A. Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. J. Neurosci. 17, 9492-9505 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 9492-9505
-
-
Tongiorgi, E.1
Righi, M.2
Cattaneo, A.3
-
63
-
-
0033613422
-
Neurotrophin-evoked rapid excitation through TrkB receptors
-
Kafitz, K. W., Rose, C. R., Thoenen, H. & Konnerth, A. Neurotrophin-evoked rapid excitation through TrkB receptors. Nature 401, 918-921 (1999).
-
(1999)
Nature
, vol.401
, pp. 918-921
-
-
Kafitz, K.W.1
Rose, C.R.2
Thoenen, H.3
Konnerth, A.4
-
64
-
-
0036500605
-
Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation
-
Kovalchuk, Y., Hanse, E., Kafitz, K. W. & Konnerth, A. Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation. Science 295, 1729-1734 (2002).
-
(2002)
Science
, vol.295
, pp. 1729-1734
-
-
Kovalchuk, Y.1
Hanse, E.2
Kafitz, K.W.3
Konnerth, A.4
-
65
-
-
0028893653
-
Morphogenetic effect of kainate on adult hippocampal neurons associated with a prolonged expression of brain-derived neurotrophic factor
-
Suzuki, F., Junior, M. P., Guilhem, D., Sorensen, J. C. & Onteniente, B. Morphogenetic effect of kainate on adult hippocampal neurons associated with a prolonged expression of brain-derived neurotrophic factor. Neuroscience 64, 665-674 (1995).
-
(1995)
Neuroscience
, vol.64
, pp. 665-674
-
-
Suzuki, F.1
Junior, M.P.2
Guilhem, D.3
Sorensen, J.C.4
Onteniente, B.5
-
66
-
-
0033571962
-
BDNF modulates, but does not mediate, activity-dependent branching and remodeling of optic axon arbors in vivo
-
Cohen-Cory, S. BDNF modulates, but does not mediate, activity-dependent branching and remodeling of optic axon arbors in vivo. J. Neurosci. 19, 9996-10003 (1999).
-
(1999)
J. Neurosci.
, vol.19
, pp. 9996-10003
-
-
Cohen-Cory, S.1
-
67
-
-
0032957382
-
Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
-
Young, D., Lawlor, P. A., Leone, P., Dragunow, M. & During, M. J. Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nature Med. 5, 448-453 (1999).
-
(1999)
Nature Med.
, vol.5
, pp. 448-453
-
-
Young, D.1
Lawlor, P.A.2
Leone, P.3
Dragunow, M.4
During, M.J.5
-
68
-
-
0035783908
-
Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus
-
Berchtold, N. C., Kesslak, J. P., Pike, C. J., Adlard, P. A. & Cotman, C. W. Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus. Eur J. Neurosci. 14, 1992-2002 (2001).
-
(2001)
Eur J. Neurosci.
, vol.14
, pp. 1992-2002
-
-
Berchtold, N.C.1
Kesslak, J.P.2
Pike, C.J.3
Adlard, P.A.4
Cotman, C.W.5
-
69
-
-
0032863708
-
Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression
-
Russo-Neustadt, A., Beard, R. C. & Cotman, C. W. Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression. Neuropsychopharmacology 21, 679-682 (1999).
-
(1999)
Neuropsychopharmacology
, vol.21
, pp. 679-682
-
-
Russo-Neustadt, A.1
Beard, R.C.2
Cotman, C.W.3
-
70
-
-
0032579757
-
Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus
-
Lauterborn, J. C., Poulsen, F. R., Stinis, C. T., Isackson, P. J. & Gall, C. M. Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus. Brain Res. Mol. Brain Res. 55, 81-91 (1998).
-
(1998)
Brain Res. Mol. Brain Res.
, vol.55
, pp. 81-91
-
-
Lauterborn, J.C.1
Poulsen, F.R.2
Stinis, C.T.3
Isackson, P.J.4
Gall, C.M.5
-
71
-
-
0033994676
-
Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons
-
Lauterborn, J. C., Lynch, G., Vanderklish, P., Arai, A. & Gall, C. M. Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. J. Neurosci. 20, 8-21 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 8-21
-
-
Lauterborn, J.C.1
Lynch, G.2
Vanderklish, P.3
Arai, A.4
Gall, C.M.5
-
72
-
-
0037466396
-
Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain
-
Dicou, E., Rangon, C. M., Guimiot, F., Spedding, M. & Gressens, P. Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain. Brain Res. 970, 221-225 (2003).
-
(2003)
Brain Res.
, vol.970
, pp. 221-225
-
-
Dicou, E.1
Rangon, C.M.2
Guimiot, F.3
Spedding, M.4
Gressens, P.5
-
73
-
-
0037993807
-
New directions for drug discovery in psychiatric disease
-
Spedding, M., Sebban, C. & Perrot, L. New directions for drug discovery in psychiatric disease. Dialogues Clin. Neurosci. 4, 336-341 (2002).
-
(2002)
Dialogues Clin. Neurosci.
, vol.4
, pp. 336-341
-
-
Spedding, M.1
Sebban, C.2
Perrot, L.3
-
74
-
-
0142095005
-
NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: Toward a paradigm shift in medication development
-
Krystal, J. H. et al. NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development. Psychopharmacology (Berl) 169, 215-233 (2003).
-
(2003)
Psychopharmacology (Berl.)
, vol.169
, pp. 215-233
-
-
Krystal, J.H.1
-
75
-
-
0037084503
-
Reduced volume of orbitofrontal cortex in major depression
-
Bremner, J. D. et al. Reduced volume of orbitofrontal cortex in major depression. Biol. Psychiatry 51, 273-279 (2002).
-
(2002)
Biol. Psychiatry
, vol.51
, pp. 273-279
-
-
Bremner, J.D.1
-
76
-
-
1842481232
-
Lower hippocampal volume in patients suffering from depression: A meta-analysis
-
Campbell, S., Marriott, M., Nahmias, C. & MacQueen, G. M. Lower hippocampal volume in patients suffering from depression: a meta-analysis. Am. J. Psychiatry 161, 598-607 (2004).
-
(2004)
Am. J. Psychiatry
, vol.161
, pp. 598-607
-
-
Campbell, S.1
Marriott, M.2
Nahmias, C.3
MacQueen, G.M.4
-
77
-
-
0036581111
-
Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: Rapid actions of serotonergic and antidepressant agents
-
Shakesby A. C., Anwyl, R. & Rowan, M. J. Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: rapid actions of serotonergic and antidepressant agents. J. Neurosci. 22, 3638-3644 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 3638-3644
-
-
Shakesby, A.C.1
Anwyl, R.2
Rowan, M.J.3
-
78
-
-
0035940496
-
Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
-
Czeh, B. et al. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc. Natl Acad. Sci. USA 98, 12796-12801 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12796-12801
-
-
Czeh, B.1
-
79
-
-
0027234374
-
Trial 2 in the elevated plus-maze: A different form of fear?
-
File, S. E., Zangrossi, H., Jr., Viana, M. & Graeff, F. G. Trial 2 in the elevated plus-maze: a different form of fear? Psychopharmacology (Berl) 111, 491-494 (1993).
-
(1993)
Psychopharmacology (Berl.)
, vol.111
, pp. 491-494
-
-
File, S.E.1
Zangrossi Jr., H.2
Viana, M.3
Graeff, F.G.4
-
80
-
-
0033874065
-
Effects of two acute stressors on the anxiolytic efficacy of chlordiazepoxide
-
Haller, J. & Halasz, J. Effects of two acute stressors on the anxiolytic efficacy of chlordiazepoxide. Psychopharmacology (Berl) 151, 1-6 (2000).
-
(2000)
Psychopharmacology (Berl.)
, vol.151
, pp. 1-6
-
-
Haller, J.1
Halasz, J.2
-
81
-
-
0037111981
-
Molecular targets in the treatment of anxiety
-
Kent, J. M., Mathew, S. J. & Gorman, J. M. Molecular targets in the treatment of anxiety. Biol. Psychiatry 52, 1008-1030 (2002).
-
(2002)
Biol. Psychiatry
, vol.52
, pp. 1008-1030
-
-
Kent, J.M.1
Mathew, S.J.2
Gorman, J.M.3
-
82
-
-
0023215296
-
Implications of normal brain development for the pathogenesis of schizophrenia
-
Weinberger, D. R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry 44, 660-669 (1987).
-
(1987)
Arch. Gen. Psychiatry
, vol.44
, pp. 660-669
-
-
Weinberger, D.R.1
-
83
-
-
0032788369
-
Inhibitory cartridge synapses in the anterior cingulate cortex of schizophrenics
-
Kalus, P., Senitz, D., Lauer, M. & Beckmann, H. Inhibitory cartridge synapses in the anterior cingulate cortex of schizophrenics. J. Neural. Transm. 106, 763-771 (1999).
-
(1999)
J. Neural. Transm.
, vol.106
, pp. 763-771
-
-
Kalus, P.1
Senitz, D.2
Lauer, M.3
Beckmann, H.4
-
84
-
-
0343851634
-
Developmental malformations in cerebral structures of schizophrenic patients
-
Beckmann, H. Developmental malformations in cerebral structures of schizophrenic patients. Eur. Arch. Psychiatry Clin. Neurosci. 249 (Suppl. 4), 44-47 (1999).
-
(1999)
Eur. Arch. Psychiatry Clin. Neurosci.
, vol.249
, Issue.SUPPL. 4
, pp. 44-47
-
-
Beckmann, H.1
-
85
-
-
0036719133
-
Sex differences in temporo-limbic and frontal brain volumes of healthy adults
-
Gur, R. C., Gunning-Dixon, F., Bilker, W. B. & Gur, R. E. Sex differences in temporo-limbic and frontal brain volumes of healthy adults. Cereb. Cortex 12, 998-1003 (2002).
-
(2002)
Cereb. Cortex
, vol.12
, pp. 998-1003
-
-
Gur, R.C.1
Gunning-Dixon, F.2
Bilker, W.B.3
Gur, R.E.4
-
86
-
-
0026467216
-
Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Assessment with xenon 133 single-photon emission computed tomography and the Tower of London
-
Andreasen, N. C. et al. Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Assessment with xenon 133 single-photon emission computed tomography and the Tower of London. Arch. Gen. Psychiatry 49, 943-958 (1992).
-
(1992)
Arch. Gen. Psychiatry
, vol.49
, pp. 943-958
-
-
Andreasen, N.C.1
-
87
-
-
0032719083
-
The neuropathological effects of antipsychotic drugs
-
Harrison, P. J. The neuropathological effects of antipsychotic drugs. Schizophr. Res. 40, 87-99 (1999).
-
(1999)
Schizophr. Res.
, vol.40
, pp. 87-99
-
-
Harrison, P.J.1
-
88
-
-
0036337907
-
Brain development in healthy, hyperactive, and psychotic children
-
Gogtay, N., Giedd, J. & Rapoport, J. L. Brain development in healthy, hyperactive, and psychotic children. Arch. Neurol. 59, 1244-1248 (2002).
-
(2002)
Arch. Neurol.
, vol.59
, pp. 1244-1248
-
-
Gogtay, N.1
Giedd, J.2
Rapoport, J.L.3
-
89
-
-
0038669298
-
Studies in schizophrenia: Pathophysiology and treatment
-
Tamminga, C. A. & Medoff, D. R. Studies in schizophrenia: pathophysiology and treatment. Dialogues Clin. Neurosci. 4, 432-437 (2002).
-
(2002)
Dialogues Clin. Neurosci.
, vol.4
, pp. 432-437
-
-
Tamminga, C.A.1
Medoff, D.R.2
-
90
-
-
0037143728
-
Dissociable prefrontal brain systems for attention and emotion
-
Yamasaki, H., LaBar, K. S. & McCarthy, G. Dissociable prefrontal brain systems for attention and emotion. Proc. Natl Acad. Sci. USA 99, 11447-11451 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11447-11451
-
-
Yamasaki, H.1
LaBar, K.S.2
McCarthy, G.3
-
92
-
-
2942590540
-
The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment: A comparison with tianeptine
-
Burghardt, N. S., Sullivan, G. M., McEwen, B. S., Gorman, J. M. & LeDoux, J. E. The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment: a comparison with tianeptine. Biol. Psychiatry 55, 1171-1178 (2004).
-
(2004)
Biol. Psychiatry
, vol.55
, pp. 1171-1178
-
-
Burghardt, N.S.1
Sullivan, G.M.2
McEwen, B.S.3
Gorman, J.M.4
LeDoux, J.E.5
-
93
-
-
0036324455
-
Structural plasticity and tianeptine: Cellular and molecular targets
-
McEwen, B. S., Magarinos, A. M. & Reagan, L. P. Structural plasticity and tianeptine: cellular and molecular targets. Eur. Psychiatry 17 (Suppl. 3), 318-330 (2002).
-
(2002)
Eur. Psychiatry
, vol.17
, Issue.SUPPL. 3
, pp. 318-330
-
-
McEwen, B.S.1
Magarinos, A.M.2
Reagan, L.P.3
-
94
-
-
1642421311
-
Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex
-
Radley, J. J. et al. Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex. Neuroscience 125, 1-6 (2004).
-
(2004)
Neuroscience
, vol.125
, pp. 1-6
-
-
Radley, J.J.1
|