Cytotoxic activity of 3-nitropyrazolo[5,1-c][1,2,4]benzotriazine derivatives: A new series of anti-proliferative agents

Anti-Cancer Drugs

Volumn 16, Issue 6, 2005, Pages 645-651

  Coronnello, Marcella ^a,b   Ciciani, Giovanna ^a   Mini, Enrico ^a   Guerrini, Gabriella ^a   Caciagli, Barbara ^a   Selleri, Silvia ^a   Costanzo, Annarella ^a   Mazzei, Teresita ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Department of Preclinical and Clinical Pharmacology ^*  (Italy)

Author keywords

Apoptosis; Cell cycle; Cell growth inhibition; Established human carcinoma cell lines; Pyrazolo 5,1 c 1,2,4 benzotriazine system

Indexed keywords

3 CYANO 8 CHLOROPYRAZOLO[5,1 C] 1,2,4 BENZOTRIAZINE 5 OXIDE; 3 NITROPYRAZOLO[5,1 C] 1,2,4BENZOTRIAZINE DERIVATIVE; DOXORUBICIN; MITOMYCIN C; NSC 683334; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN A549; CELL STRAIN HCT 8; CELL STRAIN HT29; CELL STRAIN MCF 7; COLON CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS INHIBITION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; LUNG CARCINOMA; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; HT29 CELLS; HUMANS; LUNG NEOPLASMS; PYRAZOLES; TRIAZINES;

EID: 20844441761     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-200507000-00009     Document Type: Article

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