SCOPUS 정보 검색 플랫폼

Volumn 45, Issue 3, 2002, Pages 740-743

Structure-activity relationships for pyrido-, imidazo-, pyrazolo-, pyrazino-, and pyrrolophenazinecarboxamides as topoisomerase-targeted anticancer agents

(10) Gamage, Swarna A a Spicer, Julie A a Rewcastle, Gordon W a Milton, John b Sohal, Sukhjit b Dangerfield, Wendy b Mistry, Prakash b Vicker, Nigel b Charlton, Peter A b Denny, William A a

a UNIVERSITY OF AUCKLAND (New Zealand)

b Cantab Pharmaceuticals Ltd (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHOXYPYRIDO[4,3 A]PHENAZINE DERIVATIVE; AMIDE; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; GLYCOPROTEIN P; GYRASE INHIBITOR; HETEROCYCLIC COMPOUND; IMIDAZOPHENAZINECARBOXAMIDE DERIVATIVE; NITROBENZOIC ACID DERIVATIVE; PHENAZINE DERIVATIVE; PYRAZINOPHENAZINECARBOXAMIDE DERIVATIVE; PYRAZOLOPHENAZINECARBOXAMIDE DERIVATIVE; PYRIDO[4,3 A]PHENAZINE DERIVATIVE; PYRIDOPHENAZINECARBOXAMIDE DERIVATIVE; PYRROLOPHENAZINECARBOXAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

AMIDATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CYCLIZATION; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; POLYMERIZATION; REDUCTION; STRUCTURE ACTIVITY RELATION;

AMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; DNA TOPOISOMERASES, TYPE II; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; INTERCALATING AGENTS; MICE; NEOPLASM TRANSPLANTATION; P-GLYCOPROTEIN; PHENAZINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0037204011 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm010330+ Document Type: Article

Times cited : (142)

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