The Caenorhabditis elegans Skp1-related gene family: Diverse functions in cell proliferation, morphogenesis, and meiosis

Current Biology

Volumn 12, Issue 4, 2002, Pages 277-287

  Nayak, Sudhir ^a   Santiago, Fernando E ^b   Jin, Hui ^b   Lin, Debbie ^a   Schedl, Tim ^a   Kipreos, Edward T ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS;

CAENORHABDITIS ELEGANS PROTEIN; CELL CYCLE PROTEIN; CULLIN; CULLIN 1; RNA; S PHASE KINASE ASSOCIATED PROTEIN;

ANIMAL; ARTICLE; CAENORHABDITIS ELEGANS; CELL DIVISION; CHEMISTRY; CYTOLOGY; FEMALE; GENE ORDER; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; INFERTILITY; MEIOSIS; METABOLISM; MOLECULAR GENETICS; MORPHOGENESIS; MULTIGENE FAMILY; MUTATION; NUCLEOTIDE SEQUENCE; PHENOTYPE; PHYLOGENY; PRENATAL DEVELOPMENT; PROTEIN BINDING; SEQUENCE HOMOLOGY; TWO HYBRID SYSTEM;

ANIMALS; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL CYCLE PROTEINS; CELL DIVISION; CULLIN PROTEINS; FEMALE; GENE ORDER; HUMANS; INFERTILITY; MEIOSIS; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; MULTIGENE FAMILY; MUTATION; PHENOTYPE; PHYLOGENY; PROTEIN BINDING; RNA; S-PHASE KINASE-ASSOCIATED PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 0037133036     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00682-6     Document Type: Article

References (50)

1. skp2 are essential elements of the cyclin A-CDK2 S phase kinase
2. SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
3. F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
4. A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
5. Proteolysis and the cell cycle: With this RING I do thee destroy
6. SCF and cullin/ring H2-based ubiquitin ligases
7. Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex
8. The ubiquitin system
9. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line
10. Fbw7 ubiquitin ligase
11. Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1 p-mediated phosphorylation
12. The unstable F-box protein p58-Ctf13 forms the structural core of the CBF3 kinetochore complex
13. Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast
14. Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly
15. Gapped BLAST and PSIBLAST: A new generation of protein database search programs
16. Human inner ear OCP2 cDNA maps to 5q22-5q35.2 with related sequences on chromosomes 4p16.2-4p14, 5p13-522, 7pter-q22, 10 and 12p13-12qter
17. Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1 A and SKP1 B) and p45 (SKP2)
18. The neighbor-joining method: A new method for reconstructing phylogenetic trees
19. Evolutionary trees from DNA sequences: A maximum likelihood approach
20. Escaping from the Felsenstein zone by detecting long branches in phylogenetic data
21. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
22. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
23. Functional anatomy of a dsRNA trigger. Differential requirement for the two trigger strands in RNA interference
24. The embryonic cell lineage of the nematode Caenorhabditis elegans
25. Cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family
26. A global profile of germline gene expression in C. elegans
27. RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans
28. Genomic analysis of gene expression in C. elegans
29. RNA-mediated interference of a cdc25 homolog in Caenorhabditis elegans results in defects in the embryonic cortical membrane, meiosis, and mitosis
30. CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans
31. The rde-1 gene, RNA interference, and transposon silencing in C. elegans
32. GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development
33. Synapsis and chiasma formation in Caenorhabditis elegans require HIM-3, a meiotic chromosome core component that functions in chromosome segregation
34. Monoclonal antibodies that recognize a polypeptide antigenic determinant shared by multiple Caenorhabditis elegans sperm-specific proteins
35. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
36. The F-box protein family
37. Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A
38. Three genes of the MAP kinase cascade, mek-2, mpk-1/sur-1 and let-60 ras, are required for meiotic cell cycle progression in Caenorhabditis elegans
39. Gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans
40. Analysis of the multiple roles of gld-1 in germline development: Interactions with the sex determination cascade and the glp-1 signaling pathway
41. Caenorhabditis elegans homologue of the human azoospermia factor DAZ is required for oogenesis but not for spermatogenesis
42. Germline and developmental roles of the nuclear transport factor importin alpha3 in C. elegans
43. Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2
44. Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis
45. RNAi - Prospects for a general technique for determining gene function
46. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
47. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
48. Developmental genetics of the germ line
49. Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte