Thrombin modulates the expression of a set of genes including thrombospondin-1 in human microvascular endothelial cells

Journal of Biological Chemistry

Volumn 280, Issue 23, 2005, Pages 22172-22180

  McLaughlin, Joseph N ^a   Mazzoni, Maria R ^a,c   Cleator, John H ^a,b   Earls, Laurie ^a   Perdigoto, Ana Luisa ^a   Brooks, Joshua D ^a   Muldowney III, James A S ^b   Vaughan, Douglas E ^b   Hamm, Heidi E ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CELLS; CONCENTRATION (PROCESS); DISEASES; ENZYME INHIBITION; GENES; GENETIC ENGINEERING; TOXIC MATERIALS; TUMORS;

ANGIOGENESIS; PLATELETS; VASCULATURE SYSTEMS; WOUND HEALING;

ENZYME KINETICS;

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CONNECTIVE TISSUE GROWTH FACTOR; EARLY GROWTH RESPONSE FACTOR 1; G PROTEIN COUPLED RECEPTOR; MYC PROTEIN; PEPTIDE; PERTUSSIS TOXIN; PLASMINOGEN ACTIVATOR; PROTEIN KINASE C; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; RHO KINASE; THREONYLPHENYLALANYLLEUCYLLEUCYLARGINYLASPARAGYLLYSYLPROLYLASPARTYLLYSINE; THROMBIN; THROMBOSPONDIN 1; UNCLASSIFIED DRUG;

ARTICLE; BLOOD VESSEL INJURY; CELL LEVEL; CELL STIMULATION; CONTROLLED STUDY; DNA MICROARRAY; ENDOTHELIUM CELL; ENZYME INHIBITION; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; UPREGULATION;

ADENOSINE DIPHOSPHATE; ALGORITHMS; AMIDES; APOPTOSIS; CELLS, CULTURED; CLUSTER ANALYSIS; CULTURE MEDIA; DNA PRIMERS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC IMPEDANCE; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; INDOLES; MALEIMIDES; MICROCIRCULATION; MODELS, BIOLOGICAL; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDES; PERTUSSIS TOXIN; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PYRIDINES; RECEPTOR, PAR-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIGNAL TRANSDUCTION; THROMBIN; THROMBOSPONDIN 1; TIME FACTORS; UMBILICAL VEINS; UP-REGULATION;

EID: 20444493195     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500721200     Document Type: Article

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