Amlodipine inhibition of serum-, thrombin-, or fibroblast growth factor- induced vascular smooth-muscle cell proliferation

Journal of Cardiovascular Pharmacology

Volumn 31, Issue 5, 1998, Pages 786-793

  Stepien, Olivier ^a   Gogusev, Jean ^b   Zhu, Ding Liang ^c   Iouzalen, Lahcen ^a   Herembert, Thierry ^a   Drucke, Tilman B ^b   Marche, Pierre ^a,b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

Atherosclerosis; bFGF; c fos; c jun; c myc; Cell cycle; Dihydropyridine; DNA synthesis; Nifedipine; Protooncogene; Thrombin

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; AMLODIPINE; ANTIMITOTIC AGENT; BASIC FIBROBLAST GROWTH FACTOR; BROXURIDINE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL STIMULATING AGENT; DNA; HYDROXYUREA; MYC PROTEIN; NIFEDIPINE; ONCOPROTEIN; PROTEIN C FOS; THROMBIN;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DRUG ANTAGONISM; DRUG EFFECT; FETAL CALF SERUM; GENE EXPRESSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

AMLODIPINE; ANIMALS; ANTIHYPERTENSIVE AGENTS; CALCIUM CHANNELS; CELL DIVISION; DNA; FIBROBLAST GROWTH FACTORS; MALE; MUSCLE, SMOOTH, VASCULAR; ONCOGENES; RATS; RATS, INBRED WKY; THROMBIN;

EID: 0031980276     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199805000-00019     Document Type: Article

References (49)

1. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801-9.
2. Mogami H, Kojima I. Stimulation of calcium entry is a prerequisite for DNA synthesis induced by platelet-derived growth factor in vascular smooth muscle cells. Biochem Biophys Res Commun 1993;196:650-8.
3. 2+ pool content is linked to control of cell growth. Proc Natl Acad Sci U S A 1993;90:4986-90.
4. Jackson CL, Schwartz SM. Pharmacology of smooth muscle cell replication. Hypertension 1992;20:713-36.
5. Nayler WG. Amlodipine. Berlin: Springer-Verlag, 1993.
6. 2+-channel blockers modulate expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and low density lipoprotein receptor genes stimulated by platelet-derived growth factor. Proc Natl Acad Sci U S A 1991;88:9041-5.
7. Matlib MA, French JF, Grupp IL, Van Corp C, Grupp G, Schwartz A. Vasodilatory action of amlodipine on rat aorta, pig coronary artery, human coronary artery, and on isolated Langendorft rat heart preparations. J Cardiovasc Pharmacol 1988;12(suppl 7):S50-4.
8. Fleckenstein A, Frey M, Zorn J, Fleckenstein-Grun G. Amlodipine, a new 1,4-dihydropyridine calcium antagonist with a particularly strong antihypertensive profile. Am J Cardiol 1989;64:21-341.
9. Shultz PJ, Raij L. Effect of amlodipine on mesangial cell proliferation and protein synthesis. Am J Hypertens 1992;5:912-4.
10. Campbell JH, Black MJ, Campbell GR. Replication of smooth muscle cells in atherosclerosis and hypertension. In: Meyer P, Marche P, eds. Blood cells and arteries in hypertension and atherosclerosis. New York: Raven Press, 1989:15-33.
11. Lindner V, Lappi DA, Baird A, Majack RA, Reidy MA. Role of basic fibroblast growth factor in vascular lesion formation. Circ Res 1991;68:106-13.
12. Fager G. Thrombin and proliferation of vascular smooth muscle cells. Circ Res 1995;77:645-50.
13. McNamara CA, Sarembock IJ, Bachhuber BG, et al. Thrombin and vascular smooth muscle cell proliferation: implications for atherosclerosis and restenosis. Semin Thromb Hemost 1996;22:139-44.
14. Ross R. The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers. J Cell Biol 1971;50:172-6.
15. Ashihara T, Baserea R. Cell synchronization. Methods Enzymol 1979;58:248-62.
16. Uehara Y, Kawabata Y, Hirawa N, et al. OPC-13340, a new dihydropyridine calcium channel blocker attenuates rapid vascular smooth muscle cell growth in spontaneously hypertensive rats. J Cardiovasc Pharmacol 1992;20:408-15.
17. Kueng W, Silber F, Eppenberger U. Quantification of cells cultured on 96-well plates. Anal Biochem 1989;182:16-9.
18. Zhu DL, Hérembert T, Marche P. Increased proliferation of adventitial fibroblasts from spontaneously hypertensive rat aorta. J Hypertens 1991;9:1161-8.
19. Chomczynski O, Sacchi N. Single step method of RNA isolation by acid guanidium thiocyanate phenol chloroform extraction. Anal Biochem 1987;162:156-9.
20. Saiki RK, Gelfand DH, Stoffel S, et al. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 1988;239:487-91.
21. Curran T, Gordon MB, Rubino KL, Sambucetti LC. Isolation and characterization of the c-fos (rat) cDNA and analysis of post-translational modification in vitro. Oncogene 1987;2:79-84.
22. Sakai M, Okuda A, Hatayama I, Sato K, Nishi S, Muramatsu M. Structure and expression of the rat c-jun messenger RNA: tissue distribution and increase during chemical hepatocarcinogenesis. Cancer Res 1989;49:5633-7.
23. Hayashi K, Makino R, Kawamura H, Arisawa A, Yoneda K. Characterization of rat c-myc and adjacent regions. Nucleic Acids Res 1987;15:6419-36.
24. Nudel U, Zakut R, Shani M, Neuman S, Levy Z, Yaffa D. The nucleotide sequence of the rat cytoplasmic β-actin gene. Nucleic Acids Res 1983;11:1759-65.
25. Leite-de-Morares MC, Herbelin A, Machavoine F, et al. MHC class I-selected CD4-CD8-TCR-αβ+ T cells are a potential source of IL-4 during primary immune response. J Immunol 1995;155:4544-50.
26. Hadrava V, Tremblay J, Sekaly RP, Hamet P. Accelerated entry of aortic smooth muscle cells from spontaneously hypertensive rats into the S phase of the cell cycle. Biochem Cell Biol 1992;70: 599-604.
27. Herschman HR. Primary response genes induced by growth factors and tumor promoters. Annu Rev Biochem 1991;60:281-319.
28. Zhu DL, Hérembert T, Caruelle D, Caruelle JP, Marche P. Involvement of calcium channels in fibroblast growth factor-induced activation of arterial cells in spontaneously hypertensive rats. J Cardiovasc Pharmacol 1994;23:395-400.
29. Hérembert T, Zhu DL, Marche P. Mechanism of action of the inhibitory effect of nifedipine on the growth of cultured aortic cells from spontaneously hypertensive and normotensive rats. Br J Pharmacol 1995;114:1703-9.
30. Jackson CL, Bush RC, Bowyer DE. Mechanism of antiatherogenic action of calcium antagonists. Atherosclerosis 1989;80:17-26.
31. Lichtlen PT, Hugenholtz PG, Rafflenbleu W, Hecker H, Jost S, Deckers JW. Retardation of angiographic progression of coronary artery disease by nifedipine: results of the International Nifedipine Trial on Antiatherosclerotic Therapy (INTACT). Lancet 1990;335:1109-13.
32. Waters D, Lespérance J, Francetich M, et al. A controlled clinical trial to assess the effect of calcium channel blocker on the progression of coronary atherosclerosis. Circulation 1990;82: 1940-53.
33. Heldin CH. Protein tyrosine kinase receptors. Cancer Surv 1996;27:7-24.
34. Zhu DL, Hérembert T, Caruelle D, Caruelle JP, Marche P. Signaling mechanisms of basic fibroblast growth factor in artenal cells from genetically hypertensive rat. Am J Hypertens 1994;7:351-6.
35. Nilsson J, Sjölund M, Pamberg L, Von Euler AM, Jonzon B, Thyberg J. The calcium antagonist nifedipine inhibits arterial smooth muscle cell proliferation. Atherosclerosis 1985;68:109-22.
36. 2+-channel blockers inhibit the action of recombinant platelet-derived growth factor in vascular smooth muscle cells. Proc Natl Acad Sci U S A 1989;86:2388-92.
37. 2+ signaling but potentiates endothelin's effect on c-fos and c-jun induction in vascular smooth muscle and glomerular mesangial cells. Am Heart J 1993;125:589-97.
38. Ko Y, Totzke G, Graack GH, et al. Action of dihydropyridine calcium antagonists on early growth response gene expression and cell growth in vascular smooth muscle cells. J Hypertens 1993;11:1171-8.
39. 2+ mobilization in smooth muscle cell. Biochem Biophys Res Commun 1989;160:758-64.
40. Pouysségur J, Seuwen K. Transmembrane receptors and intracellular pathways that control cell proliferation. Annu Rev Physiol 1992;54:195-210.
41. 2+ channel antagonists inhibit the salvage pathway for DNA synthesis in human vascular smooth muscle cells. Eur J Pharmacol 1993;244:269-75.
42. DelRio M, Ruiz E, Tejerina T. Action of elgodipine on atherosclerosis development, cell growth and oncogene expression in vascular smooth muscle cells. Gen Pharmacol 1997;28:463-8.
43. 3H]Amlodipine binding to rat cardiac membranes. J Cardiovasc Pharmacol 1991;17:587-92.
44. 2+ channels. Kidney Int 1996;49:868-79.
45. Corsini A, Bonfatti M, Quarato P, et al. Effect of the new calcium antagonist lercanidipine and its enantiomers on the migration and proliferation of arterial myocytes. J Cardiovasc Pharmacol 1996;28:687-94.
46. 2+ channel interaction. Trends Pharmacol Sci 1990;11:38-44.
47. McMurray HF, Chahwala SB. Amlodipine exerts a potent antimigrational effect on aortic smooth muscle cells in culture. J Cardiovasc Pharmacol 1992;20(suppl A):S54-6.
48. Tulenko TN, Stepp DW, Chen M, Moisey D, Laury-Kleintop L, Mason RP. Actions of the charged dihydropyridine, amlodipine, in a cell culture model of dietary atherosclerosis. J Cardiovasc Pharmacol 1995;26(suppl A):S11-7.
49. Mak IT. Boehme P. Weglicki WB. Protective effects of calcium channel blockers against free radical-impaired endothelial cell proliferation. Biochem Pharmacol 1995;50:1531-4.