Xaliproden (SR57746A) induces 5-HT1A receptors-mediated MAP kinase activation in PC12 cells

International Journal of Immunopathology and Pharmacology

Volumn 18, Issue 2, 2005, Pages 233-244

  Appert Collin, A ^a   Duong, F H T ^a   Passilly Degrace, P ^a   Bennasroune, A ^b   Poindron, P ^a   Warter, J M ^a   Gies, Jean Pierre ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b CENTRE DE NEUROCHIMIE   (France)

Author keywords

5 HT1A receptor; Akt; MAP kinases; PC12 cells; PKC; Xaliproden

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CHELERYTHRINE; CYCLIN DEPENDENT KINASE INHIBITOR 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RAS PROTEIN; SEROTONIN 1A RECEPTOR; TYROSINE KINASE RECEPTOR; XALIPRODEN;

ANIMAL CELL; ARTICLE; CELL STRAIN; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; MOTOR NEURON DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 20444486958     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463200501800206     Document Type: Article

References (35)

1. Becker E., R.M. Soler, V.J. Yuste, E. Gine, C. Sanz-Rodriguez, J. Egea, D. Martin-Zanca and J.X. Comella. 1998. Development of survival responsiveness to brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5, but not to nerve growth factor, in cultured motoneurons from chick embryo spinal cord. J. Neurosci. 18:7903.
2. Saragovi H.U., W. Zheng, S. Maliartchouk, G.M. DiGugliemo, Y.R. Mawal, A. Kamen, S.B. Woo, A.C. Cuello, T. Debeir and K.E. Neet. 1998. A TrkA-selective, fast internalizing nerve growth factor-antibody complex induces trophic but not neuritogenic signals. J. Biol. Chem. 273:34933.
3. Sendtner M., G. Pei, M. Beck, U. Schweizer and S. Wiese. 2000. Developmental motoneuron cell death and neurotrophic factors. Cell Tissue Res. 301:71.
4. Yuan Q., W. Wu, K.F. So, A.L. Cheung, D.M. Prevette and R.W. Oppenheim. 2000. Effects of neurotrophic factors on motoneuron survival following axonal injury in newborn rats. Neuroreport 11:2237.
5. Beck M., C. Karch, S. Wiese and M. Sendtner. 2001. Motoneuron cell death and neurotrophic factors: basic models for development of new therapeutic strategies in ALS. Amyotroph. Lateral. Scler. Other. Motor. Neuron. Disord. 2:S55.
6. Morooka T. and E. Nishida. 1998. Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells. J. Biol. Chem. 273:24285.
7. Novikov L.N., L.N. Novikova, P. Holmberg and J. Kellerth. 2000. Exogenous brain-derived neurotrophic factor regulates the synaptic composition of axonally lesioned and normal adult rat motoneurons. Neuroscience 100:171.
8. Van der Geer P., S. Wiley, G.D. Gish, V.K. Lai, R. Stephens, M.F. White, D. Kaplan and T. Pawson. 1996. Identification of residues that control specific binding of the She phosphotyrosine-binding domain to phosphotyrosine sites. Proc. Natl. Acad. Sci. USA 93:963.
9. Tanabe K., S. Kiryu-Seo, T. Nakamura, N. Mori, H. Tsujino, T. Ochi and H. Kiyama. 1998. Alternative expression of She family members in nerve-injured motoneurons. Brain Res. Mol. Brain Res. 53:291.
10. Ohmichi M., K. Matuoka, T. Takenawa and A.R. Saltiel. 1994. Growth factors differentially stimulate the phosphorylation of She proteins and their association with Grb2 in PC-12 pheochromocytoma cells. J. Biol. Chem. 269:1143.
11. Gill J.S., D.C. Connolly, M.J. McManus, N.J. Maihle and A.J. Windebank. 1996. Suramin induces phosphorylation of the high-affinity nerve growth factor receptor in PC12 cells and dorsal root ganglion neurons. J. Neurochem. 66:963.
12. Aronson D., J.F. Wojtaszewski, A. Thorell, J. Nygren, D. Zangen, E.A. Richter, O. Ljungqvist, R.A. Fielding and L.J. Goodyear. 1998. Extracellular-regulated protein kinase cascades are activated in response to injury in human skeletal muscle. Am. J. Physiol. 275:C555.
13. Della Rocca G.H., T. van Biesen, Y. Daaka, L.M. Lutrell and R.J. Lefkowitz. 1997. Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. J. Biol. Chem. 272:19125.
14. Pierce K.L., L.M. Luttrell and R.J. Lefkowitz. 2001. New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades. Oncogene 20:1532.
15. Schwartz M.A. and V. Baron. 1999. Interactions between mitogenic stimuli, or a thousand and one connections. Curr. Opin. Cell. Biol. 11:197.
16. Lee F.S., R. Rajagopal and M.V. Chao. 2002. Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors. Cytokine Growth Factor Rev. 13:11.
17. Fournier J., R. Steinberg, T. Gauthier, P.E. Keane, U. Guzzy, P. Soubrie and G. Le Fur. 1993. Protective effects of SR57746A in central and peripheral models of neurodegenerative disorders in rodent and primates. Neuroscience 55:629.
18. Labie C., C. Lafon, C. Marmouget, P. Saubusse, J. Fournier, P.E. Keane, G. Le Fur and P. Soubrie. 1999. Effect of the neuroprotective compound SR57746A on nerve growth factor synthesis in cultured astrocytes from neonatal rat cortex. Br. J. Pharmacol. 127:139.
19. Iwasaki Y., T. Shiojima, M. Kinoshita and K. Ikeda. 1998. SR57746A: a survival factor for motor neurons in vivo. J. Neurol. Sci. 160:892.
20. Duong F., J. Fournier, P.E. Keane, J.L. Guenet, P. Soubrie, J.M. Warter, J. Borg and P. Poindron. 1998. The effect of the nonpeptide neurotrophic compound SR57746A on the progression of the disease state of the pmn mouse. Br. J. Pharmacol. 124:811.
21. Pradines A., M. Magazin, P. Schiltz, G. Le Fur, D. Caput and P. Ferrara. 1995. Evidence for nerve growth factor-potentiating activities of the nonpeptidic compound SR57746A in PC12 cells. J. Neurochem. 64:1954.
22. Duong F.H., J.M. Warter, P. Poindron and P. Passilly. 1999. Effect of the nonpeptide neurotrophic compound SR57746A on the phenotypic survival of purified mouse motoneurons. Br. J. Pharmacol. 128:1385.
23. Marshall C. J. 1995 Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179.
24. Hill C.S. and R. Treisman. 1995. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80:199.
25. Fournier J., G. Boutot, P.E. Keane, J.P. Maffrand, G. Le Fur and P. Soubrie. 1998. The non-peptide neuroprotective agents SR57746A interacts with neurotrophin 3 to induce differentiation in the PC12 cell-line. J. Pharm. Pharmacol. 50:323.
26. Lim C.P. and X. Cao. 2001. Regulation of Stat3 activation by MEK kinase 1. J. Biol. Chem. 276:21004.
27. De Koning J.P., A.A. Soede-Bobok, A.C. Ward, A.M. Schelen, C. Antonissen, D. van Leeuwen, B. Lowenberg and I.P. Touw. 2000. STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: role for the cyclin-dependent kinase inhibitor p27(Kip1). Oncogene 19:3290.
28. Hirano T., K. Ishihara and M. Hibi. 2000. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 19:2548.
29. Della Rocca G.J., Y.V. Mukhin, M.N. Garnovskaya, Y. Daaka, G. J. Clark, L.M. Luttrell, R.J. Lefkowitz and J.R. Raymond. 1999. Serotonin 5-HT1A receptor-mediated Erk activation requires calcium/calmodulin-dependent receptor endocytosis. J. Biol. Chem. 274:4749.
30. Mukhin Y.V., M.N. Garnovskaya, G. Collinsworth, J.S. Grewal, D. Pendergrass, T. Nagai, S. Pinkney, E.L. Greene and J.R. Raymond. 2000. 5-Hydroxytryptamine1A receptor/Gibetagamma stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of src in chinese hamster ovary fibroblasts. Biochem. J. 347:61.
31. Adayev T., Y. El-SheriF, M. Barua, N.J. Penington and P. Banerjee. 1999. Agonist stimulation of the serotonin1A receptor causes suppression of anoxia-induced apoptosis via mitogen-activated protein kinase in neuronal HN2-5 cells. J. Neurochem. 72:1489.
32. Xia Z., M. Dickens, J. Raingeau, R.J. Davis and M.E. Greenberg. 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326.
33. Raymond J.R., Y.V. Mukhin, T.W. Gettys and M.N. Garnovskaya. 1999. The recombinant 5-HT1A receptor: G protein coupling and signaling pathways. Br. J. Pharmacol. 127:1751.
34. Marinissen M.J. and J.S. Gutkind. 2001. G-protein-coupled receptors and signaling networks: emerging paradigms. Trends Pharmacol. Sci. 22:368.
35. Datta S.R., A. Brunet and M.E. Greenberg. 1999. Cellular survival: a play in three Akts. Genes Dev. 13:2905.