SCOPUS 정보 검색 플랫폼

Volumn 6, Issue 6, 2005, Pages 1089-1103

Domain-selective ligand-binding modes and atomic level pharmacophore refinement in angiotensin I converting enzyme (ACE) inhibitors

(2) Tzakos, Andreas G a Gerothanassis, Ioannis P a

a UNIVERSITY OF IOANNINA (Greece)

Author keywords

Angiotensin I converting enzyme; Drug design; Inhibitors; Metalloproteins; Molecular modeling; Molecular recognition

Indexed keywords

ARGININE; ASPARAGINE; ASPARTIC ACID; BENZYL GROUP; CAPTOPRIL; CARBOXY GROUP; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRILAT; FOSINOPRILAT; FUNCTIONAL GROUP; GLUTAMINE; KETO DIPEPTIDYL CARBOXYPEPTIDASE; LISINOPRIL; METALLOPROTEINASE; PERINDOPRILAT; PHENYLALANINE; QUINAPRILAT; RAMIPRILAT; RXP 407; SERINE; THREONINE; TYROSINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BIOLOGICAL ACTIVITY; CALCULATION; CARBOXY TERMINAL SEQUENCE; CARDIOVASCULAR DISEASE; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENERGY; ENZYME INHIBITOR COMPLEX; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENE DUPLICATION; HYDROGEN BOND; HYDROPHOBICITY; KIDNEY DISEASE; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN DOMAIN; SALT BRIDGE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STACKING INTERACTION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACIDS; ANGIOTENSIN I; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BINDING SITES; CARBON; DRUG DESIGN; HYDROPHOBICITY; LIGANDS; MATRIX METALLOPROTEINASES; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; NITROGEN; STRUCTURE-ACTIVITY RELATIONSHIP; ZINC;

EID: 20444466949 PISSN: 14394227 EISSN: None Source Type: Journal
DOI: 10.1002/cbic.200400386 Document Type: Article

Times cited : (32)

References (42)

1
- 0000110931
- F. Soubrier, F. Alhenc-Gelas, C. Hubert, J. Allegrini, M. John, G. Tregear, P. Corvol, Proc. Natl. Acad. Sci. USA 1988, 85, 9386-9390.
- (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 9386-9390
- Soubrier, F.¹ Alhenc-Gelas, F.² Hubert, C.³ Allegrini, J.⁴ John, M.⁵ Tregear, G.⁶ Corvol, P.⁷

2
- 0025739667
- L. Wei, F. Alhenc-Gelas, P. Corvol, E. Clauser, J. Biol. Chem. 1991, 266, 9002-9008.
- (1991) J. Biol. Chem. , vol.266 , pp. 9002-9008
- Wei, L.¹ Alhenc-Gelas, F.² Corvol, P.³ Clauser, E.⁴

3
- 0026643458
- L. Wei, E. Clauser, F. Alhenc-Gelas, P. Corvol, J. Biol. Chem. 1992, 267, 13398-13405.
- (1992) J. Biol. Chem. , vol.267 , pp. 13398-13405
- Wei, L.¹ Clauser, E.² Alhenc-Gelas, F.³ Corvol, P.⁴

4
- 0027175193
- E. Jaspard, L. Wei, F. Alhenc-Gelas, J. Biol. Chem. 1993, 268, 9496-9503.
- (1993) J. Biol. Chem. , vol.268 , pp. 9496-9503
- Jaspard, E.¹ Wei, L.² Alhenc-Gelas, F.³

5
- 0030434802
- P. A. Deddish, L. X. Wang, H. L. Jackman, B. Michel, J. Wang, R. A. Skidgel, E. G. Erdos, J. Pharmacol. Exp. Ther. 1996, 279, 1582-1589.
- (1996) J. Pharmacol. Exp. Ther. , vol.279 , pp. 1582-1589
- Deddish, P.A.¹ Wang, L.X.² Jackman, H.L.³ Michel, B.⁴ Wang, J.⁵ Skidgel, R.A.⁶ Erdos, E.G.⁷

6
- 0030981239
- A. Michaud, T. A. Williams, M. T. Chauvet, P. Corvol, Mol. Pharmacol. 1997, 51, 1070-1076.
- (1997) Mol. Pharmacol. , vol.51 , pp. 1070-1076
- Michaud, A.¹ Williams, T.A.² Chauvet, M.T.³ Corvol, P.⁴

7
- 0031954590
- P. A. Deddish, B. Marcic, H. L. Jackman, H. Z. Wang, R. A. Skidgel, E. G. Erdos, Hypertension 1998, 31, 912-917.
- (1998) Hypertension , vol.31 , pp. 912-917
- Deddish, P.A.¹ Marcic, B.² Jackman, H.L.³ Wang, H.Z.⁴ Skidgel, R.A.⁵ Erdos, E.G.⁶

8
- 0028967315
- A. Rousseau, A. Michaud, M. T. Chauvet, M. Lenfant, P. Corvol, J. Biol. Chem. 1995, 270, 3656-3661.
- (1995) J. Biol. Chem. , vol.270 , pp. 3656-3661
- Rousseau, A.¹ Michaud, A.² Chauvet, M.T.³ Lenfant, M.⁴ Corvol, P.⁵

9
- 13044297058
- V. Dive, J. Cotton, A. Yiotakis, A. Michaud, S. Vassiliou, J. Jiracek, G. Vazeux, M. T. Chauvet, P. Cuniasse, P. Corvol, Proc. Natl. Acad. Sci. USA 1999, 96, 4330-4335.
- (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4330-4335
- Dive, V.¹ Cotton, J.² Yiotakis, A.³ Michaud, A.⁴ Vassiliou, S.⁵ Jiracek, J.⁶ Vazeux, G.⁷ Chauvet, M.T.⁸ Cuniasse, P.⁹ Corvol, P.¹⁰

10
- 0025788169
- M. R. Ehlers, J. F. Riordan, Biochemistry 1991, 30, 7118-7126.
- (1991) Biochemistry , vol.30 , pp. 7118-7126
- Ehlers, M.R.¹ Riordan, J.F.²

11
- 0030027331
- M. Azizi, A. Rousseau, E. Ezan, T. T. Guyene, S. Michelet, J. M. Grognet, M. Lenfant, P. Corvol, J. Menard, J. Clin. Invest. 1996, 97, 839-844.
- (1996) J. Clin. Invest. , vol.97 , pp. 839-844
- Azizi, M.¹ Rousseau, A.² Ezan, E.³ Guyene, T.T.⁴ Michelet, S.⁵ Grognet, J.M.⁶ Lenfant, M.⁷ Corvol, P.⁸ Menard, J.⁹

12
- 0027283916
- F. Soubrier, L. Wei, C. Hubert, E. Clauser, F. Alhenc-Gelas, P. Corvol, J. Hypertens. 1993, 11, 599-604.
- (1993) J. Hypertens. , vol.11 , pp. 599-604
- Soubrier, F.¹ Wei, L.² Hubert, C.³ Clauser, E.⁴ Alhenc-Gelas, F.⁵ Corvol, P.⁶

13
- 0027432429
- K. J. Rieger, N. Saez-Servent, M. P. Papet, J. Wdzieczak-Bakala, J. L. Morgat, J. Thierry, W. Voelter, M. Lenfant, Biochem. J. 1993, 296(2), 373-378.
- (1993) Biochem. J. , vol.296 , Issue.2 , pp. 373-378
- Rieger, K.J.¹ Saez-Servent, N.² Papet, M.P.³ Wdzieczak-Bakala, J.⁴ Morgat, J.L.⁵ Thierry, J.⁶ Voelter, W.⁷ Lenfant, M.⁸

14
- 0035063859
- J. Menard, A. A. Patchett, Adv. Protein Chem. 2001, 56, 13-75.
- (2001) Adv. Protein Chem. , vol.56 , pp. 13-75
- Menard, J.¹ Patchett, A.A.²

15
- 0037047082
- R. Candido, K. A. Jandeleit-Dahm, Z. Cao, S. P. Nesteroff, W. C. Burns, S. M. Twigg, R. J. Dilley, M. E. Cooper, T. J. Allen, Circulation 2002, 106, 246-253.
- (2002) Circulation , vol.106 , pp. 246-253
- Candido, R.¹ Jandeleit-Dahm, K.A.² Cao, Z.³ Nesteroff, S.P.⁴ Burns, W.C.⁵ Twigg, S.M.⁶ Dilley, R.J.⁷ Cooper, M.E.⁸ Allen, T.J.⁹

16
- 0036690114
- M. A. Zaman, S. Oparil, D. A. Calhoun, Nat. Rev. Drug Discovery 2002, 1, 621-636.
- (2002) Nat. Rev. Drug Discovery , vol.1 , pp. 621-636
- Zaman, M.A.¹ Oparil, S.² Calhoun, D.A.³

17
- 0023326161
- D. Mayer, C. B. Naylor, I. Motoc, G. R. Marshall, J. Comput.-Aided Mol. Des. 1987, 1, 3-16.
- (1987) J. Comput.-Aided Mol. Des. , vol.1 , pp. 3-16
- Mayer, D.¹ Naylor, C.B.² Motoc, I.³ Marshall, G.R.⁴

18
- 0027308233
- C. L. Waller, G. R. Marshall, J. Med. Chem. 1993, 36, 2390-2403.
- (1993) J. Med. Chem. , vol.36 , pp. 2390-2403
- Waller, C.L.¹ Marshall, G.R.²

19
- 0346195665
- R. Natesh, S. L. Schwager, E. D. Sturrock, K. R. Acharya, Nature 2003, 421, 551-554.
- (2003) Nature , vol.421 , pp. 551-554
- Natesh, R.¹ Schwager, S.L.² Sturrock, E.D.³ Acharya, K.R.⁴

20
- 3042732126
- R. Natesh, S. L. Schwager, H. R. Evans, E. D. Sturrock, K. R. Acharya, Biochemistry 2004, 43, 8718-8724.
- (2004) Biochemistry , vol.43 , pp. 8718-8724
- Natesh, R.¹ Schwager, S.L.² Evans, H.R.³ Sturrock, E.D.⁴ Acharya, K.R.⁵

21
- 1442286037
- A. G. Tzakos, A. S. Galanis, G. A. Spyroulias, P. Cordopatis, E. Manessi-Zoupa, I. P. Gerothanassis, Protein Eng. 2003, 16, 993-1003.
- (2003) Protein Eng. , vol.16 , pp. 993-1003
- Tzakos, A.G.¹ Galanis, A.S.² Spyroulias, G.A.³ Cordopatis, P.⁴ Manessi-Zoupa, E.⁵ Gerothanassis, I.P.⁶

22
- 0037434846
- H. M. Kim, D. R. Shin, O. J. Yoo, H. Lee, J. O. Lee, FEBS Lett. 2003, 538, 65-70.
- (2003) FEBS Lett. , vol.538 , pp. 65-70
- Kim, H.M.¹ Shin, D.R.² Yoo, O.J.³ Lee, H.⁴ Lee, J.O.⁵

23
- 0035895889
- M. Fernandez, X. Liu, M.A. Wouters, S. Heyberger, A. Husain, J. Biol. Chem. 2001, 276, 4998-5004.
- (2001) J. Biol. Chem. , vol.276 , pp. 4998-5004
- Fernandez, M.¹ Liu, X.² Wouters, M.A.³ Heyberger, S.⁴ Husain, A.⁵

24
- 0029790768
- T. A. Williams, A. Michaud, X. Houard, M. T. Chauvet, F. Soubrier, P. Corvol, Biochem. J. 1996, 318, 125-131.
- (1996) Biochem. J. , vol.318 , pp. 125-131
- Williams, T.A.¹ Michaud, A.² Houard, X.³ Chauvet, M.T.⁴ Soubrier, F.⁵ Corvol, P.⁶

25
- 0014960193
- S. H. Ferreira, L. H. Greene, V. A. Alabaster, Y. S. Bakhle, J. R. Vane, Nature 1970, 225, 379-380.
- (1970) Nature , vol.225 , pp. 379-380
- Ferreira, S.H.¹ Greene, L.H.² Alabaster, V.A.³ Bakhle, Y.S.⁴ Vane, J.R.⁵

26
- 0019274218
- R. G. Almquist, W. R. Chao, M. E. Ellis, H. L. Johnson, J. Med. Chem. 1980, 23, 1392-1398.
- (1980) J. Med. Chem. , vol.23 , pp. 1392-1398
- Almquist, R.G.¹ Chao, W.R.² Ellis, M.E.³ Johnson, H.L.⁴

27
- 0019861062
- J. A. Weare, T. A. Stewart, J. T. Gafford, E. G. Erdos, Hypertension 1981, 3, 150-53.
- (1981) Hypertension , vol.3 , pp. 150-153
- Weare, J.A.¹ Stewart, T.A.² Gafford, J.T.³ Erdos, E.G.⁴

28
- 0028180926
- R. B. Perich, B. Jackson, C. I. Johnston, Eur. J. Pharmacol. 1994, 266, 201-211.
- (1994) Eur. J. Pharmacol. , vol.266 , pp. 201-211
- Perich, R.B.¹ Jackson, B.² Johnston, C.I.³

29
- 0242690223
- K. R. Acharya, E. D. Sturrock, J. F. Riordan, M. R. Ehlers, Nat. Rev. Drug Discovery 2003, 2, 891-902.
- (2003) Nat. Rev. Drug Discovery , vol.2 , pp. 891-902
- Acharya, K.R.¹ Sturrock, E.D.² Riordan, J.F.³ Ehlers, M.R.⁴

30
- 0029762150
- F. Grams, V. Dive, A. Yiotakis, I. Yiallouros, S. Vassiliou, R. Zwilling, W. Bode, W. Stocker, Nat. Struct. Biol. 1996, 3, 671-67S.
- (1996) Nat. Struct. Biol. , vol.3
- Grams, F.¹ Dive, V.² Yiotakis, A.³ Yiallouros, I.⁴ Vassiliou, S.⁵ Zwilling, R.⁶ Bode, W.⁷ Stocker, W.⁸

31
- 0017578611
- M. A. Ondetti, B. Rubin, D. W. Cushman, Science 1977, 196, 441-444.
- (1977) Science , vol.196 , pp. 441-444
- Ondetti, M.A.¹ Rubin, B.² Cushman, D.W.³

32
- 0142102525
- P. V. Binevski, E. A. Sizova, V. F. Pozdnev, O. A. Kost, FEBS Lett. 2003, 550, 84-88.
- (2003) FEBS Lett. , vol.550 , pp. 84-88
- Binevski, P.V.¹ Sizova, E.A.² Pozdnev, V.F.³ Kost, O.A.⁴

33
- 0141958105
- L. Marinelli, A. Lavecchia, K. E. Gottschalk, E. Novellino, H. Kessler, J. Med. Chem. 2003, 46, 4393-4404.
- (2003) J. Med. Chem. , vol.46 , pp. 4393-4404
- Marinelli, L.¹ Lavecchia, A.² Gottschalk, K.E.³ Novellino, E.⁴ Kessler, H.⁵

34
- 0034713884
- M. C. Araujo, R. L. Melo, M. H. Cesari, M. A. Juliano, L. Juliano, A. K. Carmona, Biochemistry 2000, 39, 8519-8525.
- (2000) Biochemistry , vol.39 , pp. 8519-8525
- Araujo, M.C.¹ Melo, R.L.² Cesari, M.H.³ Juliano, M.A.⁴ Juliano, L.⁵ Carmona, A.K.⁶

35
- 0028871814
- A. Sali, L. Potterton, F. Yuan, H. van Vlijmen, M. Karplus, Proteins 1995, 23, 318-326.
- (1995) Proteins , vol.23 , pp. 318-326
- Sali, A.¹ Potterton, L.² Yuan, F.³ Van Vlijmen, H.⁴ Karplus, M.⁵

36
- 0027490731
- M. J. Sippl, Proteins 1993, 17, 355-362.
- (1993) Proteins , vol.17 , pp. 355-362
- Sippl, M.J.¹

37
- 0031766271
- R. A. Laskowski, M. W. MacArthur, J. M. Thornton, Curr. Opin. Struct. Biol. 1998, 8, 631-639.
- (1998) Curr. Opin. Struct. Biol. , vol.8 , pp. 631-639
- Laskowski, R.A.¹ MacArthur, M.W.² Thornton, J.M.³

38
- 0026610767
- R. Luthy, J. U. Bowie, D. Eisenberg, Nature 1992, 356, 83-85.
- (1992) Nature , vol.356 , pp. 83-85
- Luthy, R.¹ Bowie, J.U.² Eisenberg, D.³

39
- 0027180507
- C. Colovos, T. O. Yeates, Protein Sci. 1993, 2, 1511-1519.
- (1993) Protein Sci. , vol.2 , pp. 1511-1519
- Colovos, C.¹ Yeates, T.O.²

40
- 2342418543
- P. Towler, B. Staker, S. G. Prasad, S. Menon, J. Tang, T. Parsons, D. Ryan, M. Fisher, D. Williams, N. A. Dales, M. A. Patane, M. W. Pantoliano, J. Biol. Chem. 2004, 279, 17996-18007.
- (2004) J. Biol. Chem. , vol.279 , pp. 17996-18007
- Towler, P.¹ Staker, B.² Prasad, S.G.³ Menon, S.⁴ Tang, J.⁵ Parsons, T.⁶ Ryan, D.⁷ Fisher, M.⁸ Williams, D.⁹ Dales, N.A.¹⁰ Patane, M.A.¹¹ Pantoliano, M.W.¹²

41
- 0029705324
- D. S. Goodsell, G. M. Morris, A. J. Olson, J. Mol. Recognit. 1996, 9, 1-5.
- (1996) J. Mol. Recognit. , vol.9 , pp. 1-5
- Goodsell, D.S.¹ Morris, G.M.² Olson, A.J.³

42
- 0030158429
- D. M. van Aalten, R. Bywater, J. B. Findlay, M. Hendlich, R. W. Hooft, G. Vriend, J. Comput.-Aided Mol. Des. 1996, 10, 255-262.
- (1996) J. Comput.-Aided Mol. Des. , vol.10 , pp. 255-262
- Van Aalten, D.M.¹ Bywater, R.² Findlay, J.B.³ Hendlich, M.⁴ Hooft, R.W.⁵ Vriend, G.⁶

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.