Theory favors a stepwise mechanism of porphyrin degradation by a ferric hydroperoxide model of the active species of heme oxygenase

Journal of the American Chemical Society

Volumn 127, Issue 22, 2005, Pages 8204-8213

  Kumar, Devesh ^a   De Visser, Samuél P ^a   Shaik, Sason ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CHEMICAL BONDS; DATA ACQUISITION; DEGRADATION; ENZYMES; HYDROXYLATION; IRON COMPOUNDS; PROBABILITY DENSITY FUNCTION; WATER;

BIOSYSTEMS; HEME OXYGENASE (HO); HOMOLYSIS; KINETIC ISOTOPES;

PORPHYRINS;

DEUTERIUM; FERRIC HYDROPEROXIDE; HEME; HEME OXYGENASE; HYDROPEROXIDE; IRON; PORPHYRIN; UNCLASSIFIED DRUG; WATER;

ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; COMPLEX FORMATION; DEGRADATION; HOMEOSTASIS; HYDROXYLATION; IRON BALANCE; OXIDATION; PROTON TRANSPORT; THEORY;

EID: 20444399563     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0446956     Document Type: Article

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