Progressive left ventricular remodeling, myocyte apoptosis, and protein signaling cascades after myocardial infarction in rabbits

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1740, Issue 3, 2005, Pages 499-513

  Qin, Fuzhong ^a   Liang, Michelle C ^a   Liang, Chang Seng ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Infarction; MAP kinase; Mitochondria; Oxygen radical

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CASPASE 3; CASPASE 9; CYTOCHROME C; GLUTATHIONE DISULFIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; CONFERENCE PAPER; CONTROLLED STUDY; CORONARY ARTERY LIGATION; CORRELATION ANALYSIS; CYTOSOL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART INFARCTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MITOCHONDRION; HEART MUSCLE CELL; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RABBIT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CYTOPLASM; ECHOCARDIOGRAPHY; GLUTATHIONE; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; LIGATION; MALE; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RABBITS; SIGNAL TRANSDUCTION; VENTRICULAR REMODELING;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 20444382044     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2004.11.007     Document Type: Conference Paper

References (51)

1. S. Hayashidani, H. Tsutsui, M. Ikeuchi, T. Shiomi, H. Matsusaka, T. Kubota, K. Imanaka-Yoshida, T. Itoh, and A. Takeshita Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction Am. J. Physiol. Heart Circ. Physiol. 285 2003 H1229 H1235
2. W.G. Li, A. Zaheer, L. Coppey, and H.J. Oskarsson Activation of JNK in the remote myocardium after large myocardial infarction in rats Biochem. Biophys. Res. Commun. 246 1998 816 820
3. S. Bialik, D.L. Geenen, I.E. Sasson, R. Cheng, J.W. Horner, S.M. Evans, E.M. Lord, C.J. Koch, and R.N. Kitsis Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53 J. Clin. Invest. 100 1997 1363 1372
4. Q. Li, B. Li, X. Wang, A. Leri, K.P. Jana, Y. Liu, J. Kajstura, R. Baserga, and P. Anversa Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy J. Clin. Invest. 100 1997 1991 1999
5. E. Palojoki, A. Saraste, A. Eriksson, K. Pulkki, M. Kallajoki, L.M. Voipio-Pulkki, and I. Tikkanen Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats Am. J. Physiol. Heart Circ. Physiol. 280 2001 H2726 H2731
6. F. Sam, D.B. Sawyer, D.L. Chang, F.R. Eberli, S. Ngoy, M. Jain, J. Amin, C.S. Apstein, and W.S. Colucci Progressive left ventricular remodeling and apoptosis late after myocardial infarction in mouse heart Am. J. Physiol. Heart Circ. Physiol. 279 2000 H422 H428
7. G. Olivetti, R. Abbi, F. Quaini, J. Kajstura, W. Cheng, J.A. Nitahara, E. Quaini, C. Di Loreto, C.A. Beltrami, S. Krajewski, J.C. Reed, and P. Anversa Apoptosis in the failing human heart N. Engl. J. Med. 336 1997 1131 1141
8. A. Baldi, A. Abbate, R. Bussani, G. Patti, R. Melfi, A. Angelini, A. Dobrina, R. Rossiello, F. Silvestri, F. Baldi, and G. Di Sciascio Apoptosis and post-infarction left ventricular remodeling J. Mol. Cell. Cardiol. 34 2002 165 174
9. W.G. Li, L. Coppey, R.M. Weiss, and H.J. Oskarsson Antioxidant therapy attenuates JNK activation and apoptosis in the remote noninfarcted myocardium after large myocardial infarction Biochem. Biophys. Res. Commun. 280 2000 353 357
10. X.L. Ma, S. Kumar, F. Gao, C.S. Louden, B.L. Lopez, T.A. Christopher, C. Wang, J.C. Lee, G.Z. Feuerstein, and T.L. Yue Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion Circulation 99 1999 1685 1691
11. J. Narula, P. Pandey, E. Arbustini, N. Haider, N. Narula, F.D. Kolodgie, B. Dal Bello, M.J. Semigran, A. Bielsa-Masdeu, G.W. Dec, S. Israels, M. Ballester, R. Virmani, S. Saxena, and S. Kharbanda Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy Proc. Natl. Acad. Sci. U. S. A. 96 1999 8144 8149
12. I. Watanabe, M. Toyoda, J. Okuda, T. Tenjo, K. Tanaka, T. Yamamoto, H. Kawasaki, T. Sugiyama, Y. Kawarada, and N. Tanigawa Detection of apoptotic cells in human colorectal cancer by two different in situ methods: antibody against single-stranded DNA and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labeling (TUNEL) methods Jpn. J. Cancer Res. 90 1999 188 193
13. O.S. Frankfurt, J.A. Robb, E.V. Sugarbaker, and L. Villa Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis Exp. Cell Res. 226 1996 387 397
14. G.D. Pennock, D.D. Yun, P.G. Agarwal, P.H. Spooner, and S. Goldman Echocardiographic changes after myocardial infarction in a model of left ventricular diastolic dysfunction Am. J. Physiol. Heart Circ. Physiol. 273 1997 H2018 H2029
15. P.J. Fletcher, J.M. Pfeffer, M.A. Pfeffer, and E. Braunwald Left ventricular diastolic pressure-volume relations in rats with healed myocardial infarction. Effects on systolic function Circ. Res. 49 1981 618 626
16. O.W. Griffith Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine Anal. Biochem. 106 1980 207 212
17. S. Phaneuf, and C. Leeuwenburgh Cytochrome c release from mitochondria in the aging heart: a possible mechanism for apoptosis with age Am. J. Physiol., Regul. Integr. Comp. Physiol. 282 2002 R423 R430
18. O.S. Frankfurt, J.A. Robb, E.V. Sugarbaker, and L. Villa Apoptosis in breast carcinomas detected with monoclonal antibody to single-stranded DNA: relation to bcl-2 expression, hormone receptors, and lymph node metastases Clin. Cancer Res. 3 1997 465 471
19. B.P. Kang, S. Frencher, V. Reddy, A. Kessler, A. Malhotra, and L.G. Meggs High glucose promotes mesangial cell apoptosis by oxidant-dependent mechanism Am. J. Physiol., Renal. Physiol. 284 2003 F455 F466
20. Y.T. Sia, T.G. Parker, P. Liu, J.N. Tsoporis, A. Adam, and J.L. Rouleau Improved post-myocardial infarction survival with probucol in rats: effects on left ventricular function, morphology, cardiac oxidative stress and cytokine expression J. Am. Coll. Cardiol. 39 2002 148 156
21. H.J. Oskarsson, L. Coppey, R.M. Weiss, and W.G. Li Antioxidants attenuate myocyte apoptosis in the remote non-infarcted myocardium following large myocardial infarction Cardiovasc. Res. 45 2000 679 687
22. W. Cheng, B. Li, J. Kajstura, P. Li, M.S. Wolin, E.H. Sonnenblick, T.H. Hintze, G. Olivetti, and P. Anversa Stretch-induced programmed myocyte cell death J. Clin. Invest. 96 1995 2247 2259
23. T. Ide, H. Tsutsui, S. Hayashidani, D. Kang, N. Suematsu, K. Nakamura, H. Utsumi, N. Hamasaki, and A. Takeshita Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction Circ. Res. 88 2001 529 535
24. J.W. de Jong, R.G. Schoemaker, R. de Jonge, P. Bernocchi, E. Keijzer, R. Harrison, H.S. Sharma, and C. Ceconi Enhanced expression and activity of xanthine oxidoreductase in the failing heart J. Mol. Cell. Cardiol. 32 2000 2083 2099
25. Y.T. Sia, N. Lapointe, T.G. Parker, J.N. Tsoporis, C.F. Deschepper, A. Calderone, A. Pourdjabbar, J.F. Jasmin, J.F. Sarrazin, P. Liu, A. Adam, J. Butany, and J.L. Rouleau Beneficial effects of long-term use of the antioxidant probucol in heart failure in the rat Circulation 105 2002 2549 2555
26. S. Kinugawa, H. Tsutsui, S. Hayashidani, T. Ide, N. Suematsu, S. Satoh, H. Utsumi, and A. Takeshita Treatment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress Circ. Res. 87 2000 392 398
27. D. Kumar, H. Lou, and P.K. Singal Oxidative stress and apoptosis in heart dysfunction Herz 27 2002 662 668
28. R. Aikawa, I. Komuro, T. Yamazaki, Y. Zou, S. Kudoh, M. Tanaka, I. Shiojima, Y. Hiroi, and Y. Yazaki Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats J. Clin. Invest. 100 1997 1813 1821
29. A. Clerk, A. Michael, and P.H. Sugden Stimulation of multiple mitogen-activated protein kinase sub-families by oxidative stress and phosphorylation of the small heat shock protein. HSP25/27, in neonatal ventricular myocytes Biochem. J. 333 1998 581 589
30. A. Clerk, S.J. Fuller, A. Michael, and P.H. Sugden Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts J. Biol. Chem. 273 1998 7228 7234
31. K. Kato, H. Yin, J. Agata, H. Yoshida, L. Chao, and J. Chao Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion Am. J. Physiol. Heart Circ. Physiol. 285 2003 H1506 H1514
32. Z. Xia, M. Dickens, J. Raingeaud, R.J. Davis, and M.E. Greenberg Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis Science 270 1995 1326 1331
33. T.L. Yue, C. Wang, J.L. Gu, X.L. Ma, S. Kumar, J.C. Lee, G.Z. Feuerstein, H. Thomas, B. Maleeff, and E.H. Ohlstein Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart Circ. Res. 86 2000 692 699
34. F. Qin, J. Shite, and C.S. Liang Antioxidants attenuate myocyte apoptosis and improve cardiac function in heart failure: association with changes in the MAPK pathways Am. J. Physiol. Heart Circ. Physiol. 285 2003 H822 H832
35. G.Z. Feuerstein, and P.R. Young Apoptosis in cardiac diseases: stress- and mitogen-activated signaling pathways Cardiovasc. Res. 45 2000 560 569
36. S.A. Cook, P.H. Sugden, and A. Clerk Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease J. Mol. Cell. Cardiol. 31 1999 1429 1434
37. C. Communal, W.S. Colucci, A. Remondino, D.B. Sawyer, J.D. Port, S.E. Wichman, M.R. Bristow, and K. Singh Reciprocal modulation of mitogen-activated protein kinases and mitogen-activated protein kinase phosphatase 1 and 2 in failing human myocardium J. Card. Fail. 8 2002 86 92
38. M. Haneda, T. Sugimoto, and R. Kikkawa Mitogen-activated protein kinase phosphatase: a negative regulator of the mitogen-activated protein kinase cascade Eur. J. Pharmacol. 365 1999 1 7
39. Q. Liu, and P.A. Hofmann Protein phosphatase 2A-mediated cross-talk between p38 MAPK and ERK in apoptosis of cardiac myocytes Am. J. Physiol. Heart Circ. Physiol. 286 2004 H2204 H2212
40. R. von Harsdorf, P.F. Li, and R. Dietz Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis Circulation 99 1999 2934 2941
41. P. Rosini, G. De Chiara, M. Lucibello, E. Garaci, F. Cozzolino, and M. Torcia NGF withdrawal induces apoptosis in CESS B cell line through p38 MAPK activation and Bcl-2 phosphorylation Biochem. Biophys. Res. Commun. 278 2000 753 759
42. Y. Ishikawa, E. Kusaka, Y. Enokido, T. Ikeuchi, and H. Hatanaka Regulation of Bax translocation through phosphorylation at Ser-70 of Bcl-2 by MAP kinase in NO-induced neuronal apoptosis Mol. Cell. Neurosci. 24 2003 451 459
43. R.A. Kaiser, O.F. Bueno, D.J. Lips, P.A. Doevendans, F. Jones, T.F. Kimball, and J.D. Molkentin Targeted inhibition of p38 mitogen-activated protein kinase antagonizes cardiac injury and cell death following ischemia-reperfusion in vivo J. Biol. Chem. 279 2004 15524 15530
44. W.S. Choi, D.S. Eom, B.S. Han, W.K. Kim, B.H. Han, E.J. Choi, T.H. Oh, G.J. Markelonis, J.W. Cho, and Y.J. Oh Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and-9-mediated apoptotic pathways in dopaminergic neurons J. Biol. Chem. 279 2004 20451 20460
45. P. Anversa, G. Olivetti, and J.M. Capasso Cellular basis of ventricular remodeling after myocardial infarction Am. J. Cardiol. 68 1991 7D 16D
46. C.A. Beltrami, N. Fianto, M. Rocco, G.A. Feruglio, C. Puricelli, E. Cigola, F. Quaini, E.H. Sonnenblick, G. Olivetti, and P. Anversa Structural basis of end-stage failure in ischemic cardiomyopathy in humans Circulation 89 1994 151 163
47. Y.Z. Zhu, Y.C. Zhu, Z.J. Wang, Q. Lu, H.S. Lee, and T. Unger Time-dependent apoptotic development and pro-apoptotic genes expression in rat heart after myocardial infarction Jpn. J. Pharmacol. 86 2001 355 358
48. A. Abbate, G.G. Biondi-Zoccai, R. Bussani, A. Dobrina, D. Camilot, F. Feroce, R. Rossiello, F. Baldi, F. Silvestri, L.M. Biasucci, and A. Baldi Increased myocardial apoptosis in patients with unfavorable left ventricular remodeling and early symptomatic post-infarction heart failure J. Am. Coll. Cardiol. 41 2003 753 760
49. O. Akyurek, N. Akyurek, T. Sayin, I. Dincer, B. Berkalp, G. Akyol, M. Ozenci, and D. Oral Association between the severity of heart failure and the susceptibility of myocytes to apoptosis in patients with idiopathic dilated cardiomyopathy Int. J. Cardiol. 80 2001 29 36
50. Y. Chandrashekhar, S. Sen, R. Anway, A. Shuros, and I. Anand Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction J. Am. Coll. Cardiol. 43 2004 295 301
51. S. Frantz, A. Ducharme, D. Sawyer, L.E. Rohde, L. Kobzik, R. Fukazawa, D. Tracey, H. Allen, R.T. Lee, and R.A. Kelly Targeted deletion of caspase-1 reduces early mortality and left ventricular dilatation following myocardial infarction J. Mol. Cell. Cardiol. 35 2003 685 694