Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck: Evolution of a model beyond TNM staging

Current Opinion in Oncology

Volumn 12, Issue 3, 2000, Pages 229-239

  Salesiotis, Anastasios N ^a   Cullen, Kevin J ^a  

^a GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; CHORIONIC GONADOTROPIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN D; GLUTATHIONE; GLYCOPROTEIN; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; INTEGRIN; INTERLEUKIN 10; LAMININ; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P27; PROTEIN P53; THYMIDYLATE SYNTHASE; TUMOR MARKER; VASCULOTROPIN;

ANGIOGENESIS; APOPTOSIS; BIOPSY; CANCER INVASION; CELL CYCLE; DISEASE MARKER; DISEASE SEVERITY; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; HEAD AND NECK CARCINOMA; HUMAN; IMMUNOHISTOCHEMISTRY; ONCOGENE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

CARCINOMA, SQUAMOUS CELL; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; NEOPLASM STAGING; PROGNOSIS; TIME FACTORS; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 0034519444     PISSN: 10408746     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001622-200005000-00008     Document Type: Review

References (75)

1. Cancer statistics
2. Amplication of nt-2 and bcl-1 genes in squamous cell carcinoma of the larynx
3. Mechanisms of immune suppression in patients with head and neck cancer: Influence on the immune infiltrate of the cancer
4. IL-10 expression is associated with the epression of platelet-derived endothelial cell growth factor and prognosis in oral and oropharyngeal carcinoma
5. Expression of c-erb B-2 oncoprotein in cancer of the larynx in relation to invasion of the cartilaginous framework and prognosis
6. Studies of the HER-2/eu protooncogene in human breast and ovarian cancer
7. Intratumor microvessel density as a prognostic factor in cancer
8. Angiogenic factors in laryngeal carcinomas: Do they have prognostic relevance?
9. Angiogenesis: Prognostic significance in laryngeal cancer
10. Tumor angiogenesis in patients with laryngeal cancer
11. Angiogenesis vs response after combined chemoradiotherapy of squamous cell head and neck cancer
12. Predictive value of malignancy grading systems DNA content p53 and angiogenesis for stage tongue carcinomas
13. Vascular endothelial growth factor
14. Expression of the angiogenic factors vascular endothelial growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived growth factor, placenta growth factor, and plotrophin human primary breast cancer and its relation to angiogenesis
15. Expression of vascular endothelial growth factor in human oral squamous cell carcinoma: Its association with tumour progression and p5 gene status
16. Wild-type p53 and v-src opposing influence in human vascular endothelial growth factor gene expression
17. The tumor suppressor p53
18. Lessons from hereditary colorectal cancer
19. p53 serum antibodies as prognostic indicator in head and neck cancer
20. Overexpression of the p53 gene in primary and metastatic head and neck carcimoma
21. p53 expression and cell proliferation as prognostic factors in laryngeal squamous cell carcinoma
22. A new prognostic indicator for head and neck cancer: p53 serum antibodies?
23. Expression of p53 protein correlates with decreased survival in patients with areca quid chewing and smoking-associated oral squamous cell carcinomas in Taiwan
24. Apoptosis in situ, p53, bcl-2 and AgNOR counts as prognostic factors in laryngeal carcinoma
25. Radresistance and p53 status of T2 laryngeal carcinoma, analysis by immunohistochem-istry and denaturing gradient gel electrophoresis
26. Mutation of p53 in squamous cell cancer of the head and neck: Relationship to tumor cell proliferation
27. Prognostic significance of clinical parameters and biological markers in patients with squamous carcinoma of the head and neck treated with concurrent chemoradiotherapy
28. Prognostic value of p53, glutathione S-transferase p and thymidylate synthase for neoadjuvant cisplatin-based chemotherapy in head and neck cancer
29. Prognostic significance of p53 gene mutations in laryngeal cancer
30. p53 mutations and survival in colorectal cancer patients
31. Patterns of p53 gene mutations in head and neck cancer full length gene sequencing and results of primary radiotherapy
32. p53 in tumour pathology: Can we trust immunohisto-chemistry? revisited
33. Variable genetic alterations and survival in head and neck cancer
34. The prognostic significance of allelic imbalance at key chromosomal loci in oral cancer
35. Apoptosis in normal premalignant and malignant lesions of the oropharynx and oral cavity: A preliminary study
36. Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates cell death
37. Spontaneous apoptosis and the expression of p53 and bcl-2 family proteins in locally advanced head and neck cancer
38. Enhanced apoptosis correlates with poor survival in patients with laryngeal cancer but not with cell proliferation, bcl-2 or p53 expression
39. The prognostic value of spontaneous apoptosis, bax. bcl-2, and p53 in oral squamous cell carcinoma of the tongue
40. Decreased expression of bax is correlated with poor prognosis in oral and oropharyngeal carcinoma
41. Cell cycle and cancer
42. p27kip1 chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors
43. Clinical relevance of expression of the CIP/KIP cell cycle inhibitors p21 and p27 in laryngeal cancer
44. Expression of protein p27 is associated with progression and prognosis in laryngeal cancer
45. Prognostic significance of p27 expression in carcinoma of the oral cavity and oropharynx
46. Low p27 expression correlates with poor prognosis for patients with oral tongue squamous cell carcinoma
47. Expression of cyclin D1 is correlated with poor prognosis in patients with areca quid chewing-related oral squamous cell carcinomas in Taiwan
48. Prognostic significance of Poto-like Kinase (PLK) expression in squamous cell carcinomas of the head and neck
49. Analysis of surgical margins with the molecular marker etF4E: A prognostic factor in patients with head and neck cancer
50. Squamous cell carcinoma of the oropharynx: Why we fail
51. A carbohydrate domain common to both sialyl Lea and sialyl Lex is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1
52. The invasive front of carcinomas: The most important area for tumour prognosis?
53. Prognostic aspects of the loss of epithelial basement membrane components in preinvasive and invasive laryngeal carcinomas
54. E-cadherin and alpha-catenin expression in human esophageal cancer
55. Cytoplasmic accumulation of a-catenin is associated with aggressive features in laryngeal squamous cell carcinoma
56. The extension of cancer of head and neck through peripheral nerves
57. Nerve cell adhesion molecule expression in squamous cell carcinoma of the head and neck: A predictor propensity towards perineural spread
58. Role of integrins and other cell adhesion molecules in tumor progression and metastasis
59. Expression of integrins in squamous cell carcinoma of the oral cavity
60. Induction of cell migration by matrix metallopease-2 cleavage of lanin 5
61. Clinicopathologic significance of laminin-5 γ2 chain expression in squamous cell carcinoma of the tongue
62. Syndecan-1: A new prognostic marker in laryngeal cancer
63. Syndecan-1 expression has prognostic significance in head and neck carcinoma
64. Significance of 2-3 and 2-6 sialylation of Lewis A antigen in pancreas cancer
65. Immunohistochemical expression of carbohydrate antigen 19-9 in colorectal carcinoma
66. Immunohistochemical study of sialyl Lea and sa Lex antigen in oral squamous carcinoma: The association of sialyl Lea expression with the metastatic potential
67. Circulating markers in squamous cell carcinoma of the head and neck: A review
68. Immunohistochemical study of the expression of human chorionic gonadotrophin-beta in oral SCC
69. Concentration of free hCGb subunit in serum as a prognostic marker for squamous-cell carcinoma of the oral cav and oropharynx
70. Relationship of glutahione and glutahione-S-transferase to cisplatin sensitivity in human head and neck squamous carcinoma cell lines
71. Glutathione content but not glutamyl cysteine synthetase mRNA expression predicts cisplatin resistance in head and neck cancer cell lines
72. Expression of glutathione-S-transferase-p and sensitivity of human gas cells to cisplatin
73. Immunohistochemical expression of glutathione-S-transferase-P can predct chemotherapy response in patients with non-small cell lung carcinoma
74. Anticancer drugs
75. Biological markers as indicators of pathological response primary chemotherapy oral-cavity cancers