Tacrolimus (FK506) has protective actions against murine bleomycin-induced acute lung injuries

European Journal of Pharmacology

Volumn 515, Issue 1-3, 2005, Pages 169-178

  Koshika, Tadatsura ^a   Hirayama, Yoshitaka ^a   Ohkubo, Yoshitaka ^a   Mutoh, Seitaro ^a   Ishizaka, Akitoshi ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Acute lung injury; Cyclosporin A; Dexamethasone; MCP 1 (Monocyte chemoattractant protein 1); Neutrophil; Tacrolimus

Indexed keywords

BLEOMYCIN; CHEMOKINE; CYCLOSPORIN; DEXAMETHASONE; DNA; TACROLIMUS;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; EXPOSURE; FEMALE; IMMUNOHISTOCHEMISTRY; INHIBITION KINETICS; LUNG; LUNG ALVEOLUS; LUNG ALVEOLUS CELL; MORPHOLOGY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTECTION; SURVIVAL RATE; TRACHEA;

ACUTE DISEASE; ANIMALS; APOPTOSIS; BLEOMYCIN; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINES; DEXAMETHASONE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IMMUNOSUPPRESSIVE AGENTS; IN SITU NICK-END LABELING; LUNG; LUNG DISEASES; MICE; MICE, INBRED C57BL; SPECIFIC PATHOGEN-FREE ORGANISMS; SURVIVAL RATE; TACROLIMUS;

EID: 20344377165     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.03.042     Document Type: Article

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