Parallel synthesis and biological evaluation of different sizes of bicyclo[2,3]-Leu-enkephalin analogues

Biopolymers - Peptide Science Section

Volumn 80, Issue 2-3, 2005, Pages 151-163

  Gu, Xuyuan ^a   Ying, Jinfa ^a   Min, Byoung ^a   Cain, James P ^a   Davis, Peg ^b   Willey, Patrick ^b   Navratilova, Edita ^b   Yamamura, Henry I ^b   Porreca, Frank ^b   Hruby, Victor J ^a  

^a University of Arizona   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

turn mimetics; Bicyclic dipeptide; Leu enkephalin; Solid phase parallel synthesis; Synthetic methodology

Indexed keywords

AMINO ACIDS; BIOASSAY; BIOSYNTHESIS; POLYPEPTIDES; STEREOCHEMISTRY;

BICYCLIC DIPEPTIDES; BINDING AFFINITIES; BIOLOGICALLY ACTIVE LIGANDS; ENANTIOSELECTIVE SYNTHESIS;

PROTEINS;

AMINO ACID DERIVATIVE; BICYCLO COMPOUND; LEUCINE ENKEPHALIN DERIVATIVE; PEPTIDE DERIVATIVE; PEPTIDOMIMETIC DERIVATIVE; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; ENANTIOSELECTIVITY; LIGAND BINDING; METHYLATION; MOLECULAR MODEL; PARALLEL DESIGN; PEPTIDE SYNTHESIS; PROTEIN CONFORMATION; SOLID; SYSTEMATIC SYNTHESIS;

ENKEPHALIN, LEUCINE; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; RECEPTORS, OPIOID;

EID: 20344370233     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/bip.20208     Document Type: Article

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