Characterization of lipophilicity and antiproliferative activity of E-2-arylmethylene-1-tetralones and their heteroanalogues

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 819, Issue 2, 2005, Pages 283-291

  Hallgas, B ^a   Dobos, Zs ^a   Osz, E ^b   Hollosy F ^a   Schwab, R E ^a   Szabo E Z ^a   Eros, D ^a   Idei, M ^a   Keri Gy ^a   Lorand T ^b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Antiproliferative activity; Lipophilicity; Molecular library; Retention factor and CLOGP calculation; Tetralones

Indexed keywords

BIOASSAY; CHARACTERIZATION; DYES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERS; LIPIDS; MOLECULAR STRUCTURE;

ANTIPROLIFERATIVE ACTIVITIES; LIPOPHILICITY; METHYLENE BLUE; STRUCTURAL ISOMERS;

KETONES;

1 TETRALONE DERIVATIVE; 4 CHROMANONE DERIVATIVE; METHYLENE BLUE; TETRALIN DERIVATIVE;

AB INITIO CALCULATION; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG ACTIVITY; DRUG DETERMINATION; DRUG ISOLATION; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; ISOMER; LIPOPHILICITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 20244390177     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.02.014     Document Type: Article

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