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Volumn 173, Issue 5, 2005, Pages 1762-1766

Over expression of hypoxia-inducible factor-1α in renal and bladder cancer cells increases tumorigenic potency

Author keywords

Angiogenesis; Bladder; HIF 1 ; Hypoxia; Kidney; Proliferation

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA;

EID: 20244370054     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000154343.35444.09     Document Type: Article
Times cited : (24)

References (20)
  • 1
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris, A. L.: Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer, 2: 38, 2002
    • (2002) Nat Rev Cancer , vol.2 , pp. 38
    • Harris, A.L.1
  • 2
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, G. L.: Targeting HIF-1 for cancer therapy. Nat Rev Cancer, 3: 721, 2003
    • (2003) Nat Rev Cancer , vol.3 , pp. 721
    • Semenza, G.L.1
  • 3
    • 0034896089 scopus 로고    scopus 로고
    • Relation of vascular endothelial growth factor production to expression and regulation of hypoxia-inducible factor-1 alpha and hypoxia-inducible factor-2 alpha in human bladder tumors and cell lines
    • Jones, A., Fujiyama, C., Blanche, C., Moore, J. W., Fuggle, S., Cranston, D. et al: Relation of vascular endothelial growth factor production to expression and regulation of hypoxia-inducible factor-1 alpha and hypoxia-inducible factor-2 alpha in human bladder tumors and cell lines. Clin Cancer Res, 7: 1263, 2001
    • (2001) Clin Cancer Res , vol.7 , pp. 1263
    • Jones, A.1    Fujiyama, C.2    Blanche, C.3    Moore, J.W.4    Fuggle, S.5    Cranston, D.6
  • 4
    • 0037093238 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factors in human renal cancer: Relationship to angiogenesis and to the von Hippel-Lindau gene mutation
    • Turner, K. J., Moore, J. W., Jones, A., Taylor, C. F., Cuthbert-Heavens, D., Han, C. et al: Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation. Cancer Res, 62: 2957, 2002
    • (2002) Cancer Res , vol.62 , pp. 2957
    • Turner, K.J.1    Moore, J.W.2    Jones, A.3    Taylor, C.F.4    Cuthbert-Heavens, D.5    Han, C.6
  • 5
    • 0032581277 scopus 로고    scopus 로고
    • Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
    • Carmeliet, P., Dor, Y., Herbert, J. M., Fukumura, D., Brusselmans, K., Dewerchin, M. et al: Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature, 394: 485, 1998
    • (1998) Nature , vol.394 , pp. 485
    • Carmeliet, P.1    Dor, Y.2    Herbert, J.M.3    Fukumura, D.4    Brusselmans, K.5    Dewerchin, M.6
  • 6
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1 alpha is required for solid tumor formation and embryonic vascularization
    • Ryan, H. E., Lo, J. and Johnson, R. S.: HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J, 17: 3005, 1998
    • (1998) EMBO J , vol.17 , pp. 3005
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 7
    • 0033870727 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth
    • Ryan, H. E., Poloni, M., McNulty, W., Elson, D., Gassmann, M., Arbeit, J. M. et al: Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth. Cancer Res, 60: 4010, 2000
    • (2000) Cancer Res , vol.60 , pp. 4010
    • Ryan, H.E.1    Poloni, M.2    McNulty, W.3    Elson, D.4    Gassmann, M.5    Arbeit, J.M.6
  • 8
    • 0037093107 scopus 로고    scopus 로고
    • Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor
    • Hopfl, G., Wenger, R. H., Ziegler, I., Stallmach, T., Gardelle, O., Achermann, R. et al: Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor. Cancer Res, 62: 2962, 2002
    • (2002) Cancer Res , vol.62 , pp. 2962
    • Hopfl, G.1    Wenger, R.H.2    Ziegler, I.3    Stallmach, T.4    Gardelle, O.5    Achermann, R.6
  • 9
    • 0035812789 scopus 로고    scopus 로고
    • Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: Suppression of HIF-mediated gene expression by HIF-3alpha
    • Hara, S., Hamada, J., Kobayashi, C., Kondo, Y. and Imura, N.: Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha. Biochem Biophys Res Commun, 287: 808, 2001
    • (2001) Biochem Biophys Res Commun , vol.287 , pp. 808
    • Hara, S.1    Hamada, J.2    Kobayashi, C.3    Kondo, Y.4    Imura, N.5
  • 10
    • 0033152102 scopus 로고    scopus 로고
    • Enhanced expression of glucose transporter GLUT3 in tumorigenic HeLa cell hybrids associated with tumor suppressor dysfunction
    • Suzuki, T., Iwazaki, A., Katagiri, H., Oka, Y., Redpath, J. L., Stanbridge, E. J. et al: Enhanced expression of glucose transporter GLUT3 in tumorigenic HeLa cell hybrids associated with tumor suppressor dysfunction. Eur J Biochem, 262: 534, 1999
    • (1999) Eur J Biochem , vol.262 , pp. 534
    • Suzuki, T.1    Iwazaki, A.2    Katagiri, H.3    Oka, Y.4    Redpath, J.L.5    Stanbridge, E.J.6
  • 11
    • 0026083903 scopus 로고
    • Tumor anigogenesis and metastasis - Correlation in invasive breast carcinoma
    • Weidner, N., Semple, J. P., Welch, W. R. and Folkman, J.: Tumor anigogenesis and metastasis - correlation in invasive breast carcinoma. N Engl J Med, 324: 1, 1991
    • (1991) N Engl J Med , vol.324 , pp. 1
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 12
    • 15444342958 scopus 로고    scopus 로고
    • Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
    • Iyer, N. V., Kotch, L. E., Agani, F., Leung, S. W., Laughner, E., Wenger, R. H. et al: Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev, 12: 149, 1998
    • (1998) Genes Dev , vol.12 , pp. 149
    • Iyer, N.V.1    Kotch, L.E.2    Agani, F.3    Leung, S.W.4    Laughner, E.5    Wenger, R.H.6
  • 13
    • 0034676331 scopus 로고    scopus 로고
    • Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function
    • Krieg, M., Haas, R., Brauch, H., Acker, T., Flamme, I. and Plate, K. H.: Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function. Oncogene, 19: 5435, 2000
    • (2000) Oncogene , vol.19 , pp. 5435
    • Krieg, M.1    Haas, R.2    Brauch, H.3    Acker, T.4    Flamme, I.5    Plate, K.H.6
  • 14
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • Zhong, H., Chiles, K., Feldser, D., Laughner, E., Hanrahan, C., Georgescu, M.-M. et al: Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res, 60: 1041, 2000
    • (2000) Cancer Res , vol.60 , pp. 1041
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.-M.6
  • 16
    • 0035012605 scopus 로고    scopus 로고
    • HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • Laughner, E., Taghavi, P., Chiles, K., Mahon, P. C. and Semenza, G. L.: HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol, 21: 3995, 2001
    • (2001) Mol Cell Biol , vol.21 , pp. 3995
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 17
    • 0038375038 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1
    • Fukuda, R., Kelly, B. and Semenza, G. L.: Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1. Cancer Res, 63: 2330, 2003
    • (2003) Cancer Res , vol.63 , pp. 2330
    • Fukuda, R.1    Kelly, B.2    Semenza, G.L.3
  • 18
    • 0035418621 scopus 로고    scopus 로고
    • Constitutive expression of hypoxia-inducible factor-1alpha rendered pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation
    • Akakura, N., Kobayashi, M., Horuchi, I., Suzuki, A., Wang, J., Chen, J. et al: Constitutive expression of hypoxia-inducible factor-1alpha rendered pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation. Cancer Res, 61: 6548, 2001
    • (2001) Cancer Res , vol.61 , pp. 6548
    • Akakura, N.1    Kobayashi, M.2    Horuchi, I.3    Suzuki, A.4    Wang, J.5    Chen, J.6
  • 19
    • 18544384240 scopus 로고    scopus 로고
    • Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells
    • Niizeki, H., Kobayashi, M., Horuichi, I., Akakura, N., Chen, J., Wang, J., Hamada, J.-I. et al: Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells. Br J Cancer, 86: 1914, 2002
    • (2002) Br J Cancer , vol.86 , pp. 1914
    • Niizeki, H.1    Kobayashi, M.2    Horuichi, I.3    Akakura, N.4    Chen, J.5    Wang, J.6    Hamada, J.-I.7
  • 20
    • 0034529914 scopus 로고    scopus 로고
    • Suppression of tumor growth through disruption of hypoxia-inducible transcription
    • Rung, A. L., Wang, S., Klco, J M., Kaelin, W. G., Jr. and Livingston, D. M.: Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med, 6: 1335, 2000
    • (2000) Nat Med , vol.6 , pp. 1335
    • Rung, A.L.1    Wang, S.2    Klco, J.M.3    Kaelin Jr., W.G.4    Livingston, D.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.