Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target

Journal of Biological Chemistry

Volumn 280, Issue 13, 2005, Pages 12935-12943

  Wu, Qun ^a   Ding, Wei ^a   Mirza, Asra ^a   Van Arsdale, Tish ^a   Wei, Iris ^a   Bishop, W Robert ^a   Basso, Andrea ^a   McClanahan, Terri ^a   Luo, Lin ^a   Kirschmeier, Paul ^a   Gustafson, Eric ^a   Hernandezi, Marco ^a   Liu, Suxing ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GROWTH KINETICS; RNA; TUMORS;

CELL CYCLES; CELL GROWTH; CELL LINES; INTEGRATIVE GENOMICS;

GENES;

COMPLEMENTARY DNA; PROTEIN P53;

ANCHORAGE INDEPENDENT GROWTH; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CELL ULTRASTRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; FUNCTIONAL GENOMICS; GENE; GENE CLUSTER; GENE EXPRESSION; GENE IDENTIFICATION; GENE INTERACTION; GENE REPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MITOSIS INDEX; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REL A ASSOCIATED INHIBITOR 3 GENE; TUMOR GENE; TUMOR SUPPRESSOR GENE; UPREGULATION; WILD TYPE;

AGAR; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; CLUSTER ANALYSIS; DNA, COMPLEMENTARY; DOWN-REGULATION; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; GENOMICS; HELA CELLS; HUMANS; MAMMARY GLANDS, HUMAN; MODELS, GENETIC; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 20144387435     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409901200     Document Type: Article

References (34)

1. Salorafas, G. H., and Tsiotou, A. G. (2000) Br. J. Surg. 87, 149-162
2. Winer, E. P., Morrow, M., Osborne, C. K., and Harris, J. R. (2001) in Cancer: Priciples and Practice of Oncology (DeVita, V. T., Jr., Hellman, S., and Rosenberg, S. A., eds) Vol. 2, pp. 1651-1726, Lippincott Williams & Wilkins, Philadelphia, PA
3. Pisani, P., Parkin, D. M., Bray, F., and Ferlay, J. (1999) Int. J. Cancer 83, 18-29
4. Sorlie, T., Perou, C. M., Tibshirani, R., Aas, T., Geisler, S., Johnsen, H., Hastie, T., Eisen, M. B., van de Rijn, M., Jeffrey, S. S., Thorsen, T., Quist, H., Matese, J. C., Brown, P. O., Botstein, D., Eystein Lonning, P., and Borresen-Dale, A. L. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 10869-10874
5. van't Veer, L. J., Dai, H., van de Vijver, M. J., He, Y. D., Hart, A. A., Mao, M., Peterse, H. L., van der Kooy, K., Marton, M. J., Witteveen, A. T., Schreiber, G. J., Kerkhoven, R. M., Roberts, C., Linsley, P. S., Bernards, R., and Friend, S. H. (2002) Nature 415, 530-536
6. Perou, C. M., Sorlie, T., Eisen, M. B., van de Rijn, M., Jeffrey, S. S., Rees, C. A., Pollack, J. R., Ross, D. T., Johnson, H., Akslen, L. A., Fluge, O., Pergamenschikov, A., Williams, C., Zhu, S. X., Lonning, P. E., Borresen-Dale, A.-L., Brown, P. O., and Botstein, D. (2000) Nature 406, 747-752
7. Gruvberger, S., Ringner, M., Chen, Y., Panavally, S., Saal, L. H., Borg, A., Ferno, M., Peterson, C., and Meltzer, P. S. (2001) Cancer Res. 61, 5979-5984
8. Sorlie, T., Tibshirani, R., Parker, J., Hastie, T., Marron, J. S., Nobel, A., Deng, S., Johnsen, H., Pesich, R., Geisler, S., Demeter, J. Perou, C. M., Lonning, P. E., Brown, P. O., Borresen-Dale, A. L., and Botstein, D. (2003) Proc. Nat. Acad. Sci. U. S. A. 100, 8418-8423
9. van de Vijver, M. J., He, Y. D., van 't Veer, L. J., Dai, H., Hart, A. A. M., Voskuil, D. W., Schreiber, G. J., Peterse, H. L., Roberts, C., Marton, M. J., Parrish, M., Atsma, D., Witteveen, A., Glas, A., Delahaye, L., ven der Velde, T., Bartelink, H., Rodenhuis, S., Rutgers, E. T., Friend, S. H., and Bernards, R. (2002) N. Engl. J. Med. 347, 1999-2009
10. Borresen-Dale, A. L. (2003) Hum. Mutat. 21, 292-300
11. Vogelstein, B., Lane, D., and Levine, A. J. (2000) Nature 408, 307-310
12. Mirza, A., Wu, Q., Wang, L., McClanahan, T., Bishop, W. R., Gheyas, F., Ding, W., Hutchins, B., Hockenberry, T., Kirschmeier, P., Greene, J. R., and Liu, S. (2003) Oncogene. 22, 3645
13. Wang, L., Wu, Q., Qiu, P., Mirza, A., McGuirk, M., Kirschmeier, P., Greene, J. R., Wang, Y., Pickett, C. B., and Liu, S. (2001) J. Biol. Chem. 276, 43604-43610
14. Wu, Q., Kirschmeier, P., Hockenberry, T., Yang, T.-Y., Brassard, D. L., Wang, L., McClanahan, T., Black, S., Rizzi, G., Musco-Hobkinson, M. L., Mirza, A., and Liu, S. (2002) J. Biol. Chem. 277, 36329-36337
15. Eisen, M. B., Spellman, P. T., Brown, P. O., and Botstein, D. (1998) Proc. Nat. Acad. Sci. U. S. A. 95, 14863-14868
16. Liu, S., Mirza, A., and Wang, L. (2004) in Methods in Molecular Biology, Checkpoint Controls and Cancer: Methods and Protocols (Schönthal, A. H., ed) Vol. 2, pp. 33-54, Humana, Totowa, NJ
17. Harwerth, I.-M., Wels, W., Marte, B. M., and Hynes, N. E. (1992) J. Biol. Chem. 267, 15160
18. Shawver, L. K., Mann, E., Elliger, S. S., Dagger, T. C., and Arteaga, C. L. (1994) Cancer Res. 54, 1367
19. Zajchowski, D., Band, V., Paauzie, N., Tager, A., Stampfer, M., and Sager, R. (1988) Cancer Res. 48, 7041-7047
20. Niculescu, A. B., III, Chen. X., Smeets, M., Hengst, L., Prives, C., and Reed, S. I. (1998) Mol. Cell. Biol. 18, 629-643
21. Wang, X. W., Zhan, Q., Coursen, J. D., Khan, M. A., Kontny, H. U., Yu, L., Hollander, M. C., O'Connor, P. M., Fornace, A. J., Jr., and Harris, C. C. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3706-3711
22. Chen, I. T., Smith, M. L., O'Connor, P. M., and Fornace, A. J., Jr. (1995) Oncogene. 11, 1931-1937
23. Taylor, W. R., and Stark, G. R. (2001) Oncogene. 20, 1803-1815
24. Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W., and Vogelstein, B. (1997) Nature 389, 300-305
25. Katayama, H., Sasai, K., Kawai, H., Yuan, Z. M., Bondaruk, J., Suzuki, F., Fujii, S., Arlinghaus, R. B., Czerniak, B. A., and Sen, S. (2004) Nat. Genet. 36, 55-62
26. Gopalkirshman, R. V., Lam, E. W.-F., and Kedinger, C. (1998) J. Biol. Chem. 273, 10972-10978
27. Lu, H., and Levine, A. J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5154-5158
28. Liu, X., Miller, C. W., Koeffler, P. H., and Berk, A. J. (1993) Mol. Cell. Biol. 13, 3291-3300
29. Deleted in proof
30. Deleted in proof
31. Deleted in proof
32. Fei, P., Bernhard, E. J., and El-Deiry, W. S. (2002) Cancer Res. 62, 7316-7327
33. Burns, T. F., Bernhard, E. J., and El-Deiry, W. S. (2001) Oncogene. 20, 4601-4612
34. Cheng, Y., and Lotan, R. (1998) J. Biol. Chem. 273, 35008-35015