Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme

Biochemistry

Volumn 43, Issue 23, 2004, Pages 7356-7364

  Conway, Myra E ^a   Poole, Leslie B ^a   Hutson, Susan M ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL MODIFICATION; ENZYMES; HYDROGEN PEROXIDE; MASS SPECTROMETRY; MUTAGENESIS; OXIDATION; PERTURBATION TECHNIQUES; REACTION KINETICS; REDOX REACTIONS; SUBSTITUTION REACTIONS; ULTRAVIOLET SPECTROSCOPY;

MITOCHONDRIA; MUTANTS; MUTATIONS; REDOX REGULATION;

BIOCHEMISTRY;

5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; ALANINE; AMINOTRANSFERASE; CYSTEINE; DITHIOL DERIVATIVE; DITHIOTHREITOL; HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE; HYDROGEN PEROXIDE; ISOENZYME; MUTANT PROTEIN; PROTEIN CXXC; SERINE PROTEINASE; SULFENIC ACID DERIVATIVE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMOSENSITIVITY; CIRCULAR DICHROISM; DISULFIDE BOND; HUMAN; KINETICS; MASS SPECTROMETRY; MUTATION; OXIDATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; SENSOR; SITE DIRECTED MUTAGENESIS; STEADY STATE; SUBSTITUTION REACTION; ULTRAVIOLET SPECTROSCOPY;

AMINO ACID MOTIFS; CATALYSIS; CYSTEINE; DITHIONITROBENZOIC ACID; HUMANS; HYDROGEN PEROXIDE; KINETICS; MITOCHONDRIA; MODELS, MOLECULAR; MUTATION; OXIDATION-REDUCTION; PROTEIN CONFORMATION; SPECTROPHOTOMETRY; TITRIMETRY; TRANSAMINASES;

FELIS CATUS;

EID: 2942616628     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0498050     Document Type: Article

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