Preparation of a fully substituted purine library

Journal of Combinatorial Chemistry

Volumn 7, Issue 3, 2005, Pages 474-482

  Yang, Jianxin ^a   Dang, Qun ^a   Liu, Jinglin ^a   Wei, Zhonglin ^a   Wu, Jinchang ^a   Bai, Xu ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; PURINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; COMBINATORIAL LIBRARY; COOLING; CYCLIZATION; DRUG SYNTHESIS; HYDROLYSIS; METHODOLOGY; PROTON TRANSPORT; PURINE SYNTHESIS; SUBSTITUTION REACTION;

ANIMALS; ANTIVIRAL AGENTS; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIZATION; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; MOLECULAR STRUCTURE; PURINES; PYRIMIDINES;

EID: 20044387615     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc0498433     Document Type: Article

References (28)

1. Reviews: Appleman, J. R.; Erion, M. D. Exp. Opin. Invest. Drugs 1998, 7, 225-243.
2. Jacobson, K. A.; Jarvis, M. F.; Eds. Purinergic Approaches in Experimental Theraeutics; Wiley: New York, 1997.
3. Chu, C. K.; Baker, D. C.; Eds. Nucleosides and Nucleotides as Antitumor and Antiviral Agents; Plenum: New York, 1993.
4. Bonnet, P. A.; Robins, R. K. J. Med. Chem. 1993, 36, 635-653.
5. Huryn, D. M.; Okabe, M. Chem. Rev. 1992, 92, 1745-1768.
6. Jacobson, K. A.; van Galen, P. J. M.; Williams, M. J. Med. Chem. 1992, 55, 407-422.
7. (a) Schultz, C.; Link, A.; Leost, M.; Zaharevitz, D. W.; Gussio, R.; Sausville, E. A.; Meijer, L.; Kunick, C. J. Med. Chem. 1999, 42, 2909-2919.
8. (b) Ducrot, P.; Legraverend, M.; Grierson, D. S. J. Med. Chem. 2000, 43, 4098-4108.
9. (c) Norman, M. H.; Chen, N.; Chen, Z. d.; Fotsch, C.; Hale, C.; Han, N.; Hurt, R.; Jenkins, T.; Kincaid, J.; Liu, L.; Lu, Y.; Moreno, O.; Santora, V. J.; Sonnenberg, J. D.; Karbon, W. J. Med. Chem. 2000, 43, 4288-4312.
10. (d) Imbach, P.; Capraro, H. G.; Furet, P.; Mett, H.; Meyer, T.; Zimmermann, J. Bioorg. Med. Chem. Lett. 1999, 9, 91-96.
11. (e) Legraverend, M.; Ludwig, O.; Bisagni, E.; Leclerc, S.; Meijer, L.; Giocanti, N.; Sadri, R.; Favaudon, V. Bioorg. Med. Chem. 1999, 7, 1281-1293.
12. (f) Kim, C. U.; Luh, B. Y.; Misco, P. F.; Bronson, J. J.; Hitchcock, M. J. M.; Ghazzouli, I.; Martin, J. C. J. Med. Chem. 1990, 33, 1207-1213.
13. (g) Kelley, J. L.; Linn, J. J. A.; Selwayt, J. W. T. J. Med. Chem. 1991, 34, 157-160.
14. (h) Young, R. C.; Jones, M.; Milliner, K. J.; Rana, K. K.; Ward, J. G. J. Med. Chem. 1990, 33, 2073-2080.
15. Press, J. B.; Falotico, R.; Hajos, Z. G.; Sawyers, R. A.; Kanojia, R. M.; Williams, L.; Haertlein, B.; Kauffman, J. A.; Lakas-Weiss, C.; Salata, J. J. J. Med. Chem. 1992, 35, 4509-4515.
16. (j) Dhainaut, A.; Regnier, G.; Tizot, A.; Pierre, A.; Leonce, S.; Guilbaud, N.; Kraus-Berthier, L.; Atassi, G. J. Med. Chem. 1996, 39, 4099-4108.
17. (k) Havlicek, L.; Hanus, J.; Vesely, J.; Leclerc, S.; Meijer, L.; Shaw, G.; Strnad, M. J. Med. Chem. 1997, 40, 408-412.
18. Chang, Y. T.; Wignall, S. M.; Rosania, G. R.; Gray, N. S.; Hanson, S. R.; Su, A. I.; Merlie, J., Jr.; Moon, H.-S.; Sangankar, S. B.; Perez, O.; Heald, R.; Schultz, P. G. J. Med. Chem. 2001, 44, 4497-4500.
19. Bourguignon, J. J.; Desaubry, L.; Raboisson, P.; Wermuth, C.-G.; Lugnier, C. J. Med. Chem. 1997, 40, 1768-1770.
20. (a) Giner-Sorolla, A.; Segarra, J. T.; Brooks, M. H. J. Med. Chem. 1978, 21, 344-348.
21. (b) Chiosis, G.; Lucas, B.; Shtil, A.; Huezo, H.; Rosen, N. Bioorg. Med. Chem. 2002, 10, 3555-3564.
22. (c) Lucas, B.; Rosen, N.; Chiosis, G. J. Comb. Chem. 2001, 3, 518-520.
23. (a) Chorvat, R. J.; Bakthavatchalam, R.; Beck, J. P.; Gilligan, P. J.; Wilde, R. G.; Cocuzza, A. J.; Hobbs, F. W.; Cheeseman, R. S.; Curry, M.; Rescinito, J. P.; Krenitsky, P.; Chidester, D.; Yarem, J. A.; Klaczkiewicz, J. D.; Hodge, C. N.; Aldrich, P. E.; Wasserman, Z. R.; Fernandez, C. H.; Zaczek, R.; Fitzgerald, L. W.; Huang, S.-M.; Shen, H. L.; Wong, Y. N.; Chien, B. M.; Quon, C. Y.; Arvanitis, A. J. Med. Chem. 1999, 42, 833-848.
24. (b) Hammarström, L. G. J.; Meyer, M. E.; Smith, D. B.; Talamás, F. X. Tetrahedron Lett. 2003, 44, 8361-8363.
25. Albert, A.; Brown, D. J.; Wood, H. C. S. J. Chem. Soc. 1954, 5, 3832-3839.
26. Dang, Q.; Brown, B. S.; Erion, M. D. Tetrahedron Lett. 2000, 41, 6559-6562.
27. Tanji, K.; Satoh, R.; Higashino, T. Chem. Pharm. Bull. 1992, 40, 227-229.
28. Lister, J. H.; Ed. The Purines; John Wiley & Sons: New York, 1996; Vol. 54 (Suppl.).