Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae

Yeast

Volumn 22, Issue 3, 2005, Pages 219-239

  Anaul Kabir, M ^a   Kaminska, Joanna ^b   Segel, George B ^a   Bethlendy, Gabor ^a,e   Lin, Paul ^a   Della Seta, Flavio ^c,f   Blegen, Casey ^c   Swiderek, Kristine M ^d   Zoładek, Teresa ^b   Arndt, Kim T ^c,g   Sherman, Fred ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^c Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^d ZYMOGENETICS INC   (United States)

^e Combimatrix Corp ^*  (United States)

^f CNRS   (France)

^g WYETH RESEARCH   (United States)

Author keywords

Cct; Chaperonins; LST8; RSP5; SAP155; SIT4; TOR2

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHAPERONIN; PROTEIN SUBUNIT;

ALLELE; ARTICLE; CELL COMPOSITION; CONTROLLED STUDY; FUNGUS GROWTH; GENE MUTATION; GENE OVEREXPRESSION; GENETIC CONSERVATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; SACCHAROMYCES CEREVISIAE; STOICHIOMETRY;

CHAPERONINS; DNA, FUNGAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION REGULATION, FUNGAL; MASS SPECTROMETRY; MODELS, BIOLOGICAL; PLASMIDS; POLYMERASE CHAIN REACTION; PROTEIN HYBRIDIZATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION;

EID: 20044382419     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/yea.1210     Document Type: Article

References (79)

1. 1 progression in yeast. Mol Biol Cell 7: 25-42.
2. Beck T, Schmidt A, Hall MN. 1999. Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast. J Cell Biol 146: 1227-1238.
3. Berset C, Trachsel H, Altman M. 1998. The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci USA 95: 4264-4269.
4. Chen EJ, Kaiser CA. 2003. LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway. J Cell Biol 161: 333-347.
5. Cohen SN, Chang ACY, Hsu L. 1972. Nonchromosomal antibiotic resistance in bacteria: genetic transformation of Escherichia coli by R-factor DNA. Proc Natl Acad Sci USA 69: 2110-2114.
6. Crespo JL, Helliwell SB, Wiederkehr C, et al. 2004. NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae. J Biol Chem 279: 37 512-37 517.
7. Davis MT, Lee TD. 1998. Rapid protein identification using a microscale electrospray LC/MS system on an ion trap mass spectrometer. J Am Soc Mass Spectrom 9: 194-201.
8. +]. Cell 106: 171-182.
9. Ditzel L, Löwe J, Stock D, et al. 1998. Crystal structure of the thermosome, archaea; chaperonin and homolog of CCT. Cell 93: 125-138.
10. Dunn CD, Jensen RE. 2003. Suppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA. Genetics 165 35-45.
11. Düvel K, Santhanam A, Garrett S, Schneper L, Broach JR. 2003. Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast. Mol Cell 11: 1467-1478.
12. Eng JK, McCormack AL, Yates JR III. 1994. An approach to correlate tandem mass-spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom 5: 976-989.
13. Ewalt KL, Hendrick JP, Houry WA, Hartl F-U. 1997. In vivo observation of polypeptide flux through the bacterial chaperonin system. Cell 90: 491-500.
14. Feldman DE, Thulasiraman V, Ferreyra RG, Frydman J. 1999. Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC. Mol Cell 4: 1051-1061.
15. Gajewska B, Kamińska J, Jesionowska A, et al. 2001. WW domains of Rsp5p define different functions: determination of roles in fluid phase and uracil permease endocytosis in Saccharomyces cerevisiae. Genetics 157: 91-101.
16. Gavin AC, Bosche M, Krause R, et al. 2002. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415: 141-147.
17. Griffioen G, Branduardi P, Ballarini A, et al. 2001. Nucleocytoplasmic distribution of budding yeast protein kinase A regulatory subunit Bcy1 requires Zds1 and is regulated by Yak1-dependent phosphorylation of its targeting domain. Mol Cell Biol 21: 511-523.
18. Gutsche I, Essen L-O, Baumeister W. 1999. Group II chaperonins: New TRiC(k)s and turns of a folding machine. J Mol Biol 293: 295-312.
19. Hall MN. 1996. The TOR signalling pathway and growth control in yeast. Biochem Soc Trans 24: 234-239.
20. Hartl F-U, Hayer-Hartl M. 2002. Protein folding: molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295: 1852-1858.
21. Hein C, Springael J-Y, Volland C, Haguenauer-Tsapis R, André B. 1995. NPI1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase. Mol Microbiol 18: 77-87.
22. Helliwell SB, Wagner P, Kunz J, et al. 1994. TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Mol Biol Cell 5 105-118.
23. Helliwell SB, Schmidt A, Ohya Y, Hall MN. 1998. The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton. Curr Biol 8: 1211-1214.
24. Helliwell SB, Losko S, Kaiser CA. 2001. Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease. J Cell Biol 153 649-662.
25. Hill JE, Myers AM, Koerner TJ, Tzagoloff A. 1986. Yeast/E. coli shuttle vectors with multiple unique restriction sites. Yeast 2: 163-167.
26. Ho Y, Gruhler A, Heilbut A, et al. 2002. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 415: 180-183.
27. Huibregtse JM, Scheffner M, Beaudenon S, Howley PM. 1995. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci USA 92: 2563-2567.
28. Hynes G, Willison KR. 2000. Individual subunits of the eukarotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of β-actin. J Biol Chem 275: 18 985-18 994.
29. +. EMBO J 15: 6629-6640.
30. Ito H, Fukuda Y, Murata K, Kimura A. 1983. Transformation of intact yeast cells treated with alkali cations. J Bacteriol 153 163-168.
31. Jacinto E, Guo B, Arndt KT, Schmelzle T, Hall MN. 2001. TIP41 interacts with TAP42 and negatively regulates the TOR signalling pathway. Mol Cell 8: 1017-1026.
32. Jiang Y, Broach JR. 1999. Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast. EMBO J 18: 2782-2792.
33. Kamińska J, Gajewska B, Hopper AK, Zoładek T. 2003. Rsp5p, a new link between the actin cytoskeleton and endocytosis in the yeast Saccharomyces cerevisiae. Mol Cell Biol 22: 6946-6958.
34. Kunkel TA, Roberts JD, Zakour RA. 1987. Rapid and efficient site-specific mutagenesis without phenotype selection. Methods Enzymol 154: 367-382.
35. 1 progression. Cell 73: 585-596.
36. Lewis VA, Hynes G, Zheng D, Saibil H, Willison KR. 1992. T-complex polypeptide is a subunit of a heteromeric particle in the eukaryotic cytosol. Nature 358: 249-252.
37. Lin P, Sherman F. 1997. The unique hetero-oligomeric nature of the subunits in the catalytic cooperativity of the yeast Cct chaperonin complex. Proc Natl Acad Sci USA 94: 10 780-10 785.
38. Lin P, Cardillo TS, Richard LM, Segel GB, Sherman F. 1997. Analysis of mutationally altered forms of the Cct6 subunit of the chaperonin from Saccharomyces cerevisiae. Genetics 147: 1609-1633.
39. Liou AKF, Willison KR. 1997. Elucidation of the subunit orientation in CCT (chaperonin containing TCP1) from subunit composition of CCT microcomplexes. EMBO J 16: 4311-4316.
40. Liou AKF, McCormack EA, Willison KR. 1998. The chaperonin containing TCP-1 (CCT) displays a single-ring mediated dissembly and reassembly cycle. Biol Chem Hoppe-Seyler 379: 311-319.
41. Llorca O, Smyth MG, Carrascosa JL, et al. 1999. 3D reconstruction of the ATP-bound form of CCT reveals the asymmetric folding conformation of a type II chaperonin. Nature Struct Biol 6: 639-642.
42. Loewith R, Jacinto E, Wullschleger S, et al. 2002. Two TOR complexes, only one of which is rapamycin-sensitive, have distinct roles in cell growth control. Mol Cell 10: 457-468.
43. Luke MM, Della Seta F, Di Como CJ, et al. 1996. The SAP, a new family of proteins, associate and function positively with the SIT4 phosphatase. Mol Cell Biol 16: 2744-2755.
44. Maniatis T, Fritsch EF, Sambrook J. 1982. Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory Press: New York.
45. Marchal C, Haguenauer-Tsapis R, Urban-Grimal D. 2000. Casein kinase I-dependent phosphorylation within a PEST sequence and ubiquitination at nearby lysines signal endocytosis of yeast uracil permease. J Biol Chem 275: 23 608-23 614.
46. Melki R, Batelier G, Soulie S, Williams RC Jr. 1997. Cytoplasmic chaperonin containing TCP-1: structural and functional characterization. Biochemistry 36: 5817-5826.
47. Meyer AS, Gillespie JR, Walther D, et al. 2003. Closing the folding chamber of the eukaryotic chaperonin requires the transition state of ATP hydrolysis. Cell 113: 369-381.
48. O'Farrell PH. 1975. High resolution two-dimensional electrophoresis of proteins. J Biol Chem 250: 4007-4021.
49. Rademacher F, Kehren V, Stoldt VR, Ernst JF. 1998. A Candida albicans chaperonin subunits (CaCct8p) as a specific suppressors of morphogenesis and RAS phenotypes C. albicans and Saccharomyces cerevisiae. Microbiol 144: 2951-2960.
50. Raught B, Gingras AC, Sonenberg N. 2001. The target of rapamycin (TOR) proteins. Proc Natl Acad Sci USA 98: 7037-7044.
51. Rohde J, Heitman J, Cardenas ME. 2001. The TOR kinases link nutrient sensing to cell growth. J Biol Chem 276: 9583-9586.
52. Roberg KJ, Bickel S, Rowley N, Kaiser CA. 1997. Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8. Genetics 147: 1569-1584.
53. Rommelaere H, De Neve M, Melki R, Vandekerckhove J, Ampe C. 1999. The cytosolic class II chaperonin CCT recognizes delineated hydrophobic sequences in its target proteins. Biochemistry 38 3246-3257.
54. Roobol A, Sahyoun ZP, Carden MJ. 1999a. Selected subunits of the cytosolic chaperonin associate with microtubules assembled in vitro. J Biol Chem 274: 2408-2415.
55. + and ATP. J Biol Chem 274: 19 220-19 227.
56. Roobol A, Carden MJ. 1999. Subunits of the eukaryotic cytosolic chaperonin CCT do not always behave as components of a uniform hetero-oligomeric particle. Eur J Cell Biol 78: 21-32.
57. Rotin D, Staub O, Haguenauer-Tsapis R. 2000. Ubiquitination and endocytosis of plasma membrane proteins; role of Nedd4/Rsp5p family of ubiquitin-protein ligases. J Membr Biol 176: 1-17.
58. Saiki RK, Gelfand DE, Stoffel S, et al. 1988. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239: 487-491.
59. Schmelzle T, Hall MN. 2000. TOR, a central controller of cell growth. Cell 103: 253-262.
60. Schmidt A, Hall MN. 1998. Signalling to the actin cytoskeleton. Ann Rev Cell Dev Biol 14: 305-338.
61. Schmidt A, Kunz J, Hall MN. 1996. Tor2 is required for organization of the actin cytoskeleton in yeast. Proc Natl Acad Sci USA 93: 13 780-13 785.
62. Schmidt A, Bickle M, Beck T, Hall MN. 1997. The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell 88: 531-42.
63. Schmidt A, Beck T, Koller A, Kunz J, Hall MN. 1998. The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease. EMBO J 17: 6924-6931.
64. Sherman F. 2002. Getting started with the yeast. In Methods in Enzymology, Vol 350; Guide to Yeast Genetics and Molecular and Cell Biology, Part B, Guthrie C, Fink GR (eds). Academic Press: New York; 3-41.
65. Soetens O, de Craene JO, Andre B. 2001. Ubiquitin is required for sorting to the vacuole of the yeast general amino acid permease, Gap1. J Biol Chem 276: 43 949-43 957.
66. Spiess C, Meyer AS, Frydman J. 2004. Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets. Trends Cell Biol 14: 598-604.
67. Springael JY, Andre B. 1998. Nitrogen-regulated ubiquitination of the Gap1 permease of Saccharomyces cerevisiae. Mol Biol Cell 9: 1253-1263.
68. Stettler S, Chiannilkulchai N, Hermann-Le Denmat S, et al. 1993. A general suppressor of RNA polymerase I, II and II mutations in Saccharomyces cerevisiae. Mol Gen Genet 239: 169-176.
69. Stoldt V, Rademacher F, Kehren V, et al. 1996. The Cct eukaryotic chaperonin subunits of Saccharomyces cerevisiae and other yeasts. Yeast 12: 523-529.
70. 1 for progression into S phase. Mol Cell Biol 11: 2133-2148.
71. Ursic D, Culbertson MR. 1991. The yeast homolog to mouse Tcp-1 affects microtubule-mediated processes. Mol Cell Biol 11 2629-2640.
72. Vandenbol M, Jauniaux JC, Vissers S, Grenson M. 1987. Isolation of the NPR1 gene responsible for the reactivation of ammonia-sensitive amino acid permeases in Saccharomyces cerevisiae. RNA analysis and gene dosage effects. Eur J Biochem 164: 607-612.
73. Wedaman KP, Reinke A, Anderson S, et al. 2003. Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae. Mol Biol Cell 14: 1204-1220.
74. Wiatrowski HA, Carlson M. 2003. Yap1 accumulates in the nucleus in response to carbon stress in Saccharomyces cerevisiae. Eukaryot Cell 2: 19-26.
75. Yamada A, Sekiguchi M, Mimura T, Ozeki Y. 2002. The role of plant CCTα in salt- and osmotic-stress tolerance. Plant Cell Physiol 43: 1043-1048.
76. Yoshida T, Yohda M, Iida T, et al. 1997. Structural and functional characterization of homo-oligomeric complexes of α- and β-chaperonin subunits from the hyperthermophilic archaeum Thermococcus strain KS-1. J Mol Biol 273: 635-645.
77. Zheng XF, Florentino D, Chen J, Crabtree GR, Schreiber SL. 1995. TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin. Cell 82: 121-130.
78. Zoładek T, Vaduva G, Hunter LA, et al. 1995. Mutations altering the mitochondrial-cytoplasmic distribution of Mod5p implicate the actin cytoskeleton and mRNA 3′ ends and/or protein synthesis in mitochondrial delivery. Mol Cell Biol 15: 6884-6894.
79. Zoładek T, Tobiasz A, Vaduva G, et al. 1997. MDP1, a Saccharomyces cerevisiae gene involved in mitochondrial/cytoplasmic protein distribution, is identical to the ubiquitin-protein ligase gene RSP5. Genetics 145: 595-603.