Granulocyte colony-stimulating factor enhances endotoxin-induced decrease in biliary excretion of the antibiotic cefoperazone in rats

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 9, 1998, Pages 2178-2183

  Nadai, Masayuki ^a   Matsuda, Izumi ^b   Wang, Li ^c,e   Itoh, Akio ^b   Naruhashi, Kazumasa ^d   Nabeshima, Toshitaka ^b   Asai, Masaki ^b   Hasegawa, Takaaki ^c  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

^e SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BACTERIUM LIPOPOLYSACCHARIDE; BETA LACTAM ANTIBIOTIC; CEFOPERAZONE; ENDOTOXIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BILE FLOW; BILIARY EXCRETION; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EXCRETION; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTE COUNT; MALE; MEAN RESIDENCE TIME; NONHUMAN; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; URINARY EXCRETION;

EID: 0031711882     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.9.2178     Document Type: Article

References (40)

1. Ballatori, N., and A. T. Truong. 1992. Glutathione as a primary osmotic driving force in hepatic bile formation. Am. J. Physiol. 263:G617-G624.
2. Bergeron, M. G., and Y. Bergeron. 1986. Influence of endotoxin on the intrarenal distribution of gentamicin, netilmicin, tobramycin and cepharotin. Antimicrob. Agents Chemother. 29:7-12.
3. Bolder, U., H.-T. Ton-Nu, C. D. Schteingart, E. Frink, and A. F. Hofmann. 1997. Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion. Gastroenterology 112:214-225.
4. Clark, S. C., and R. Kamen. 1987. The human hematopoietic colony-stimulating factors. Sciences 236:1229-1237.
5. Eichaker, P. Q., Y. Waisman, C. Natanson, A. Farese, W. D. Hoffman, S. M. Banks and T. J. MacVittie. 1994. Cardiopulmonary effects of granulocyte colony-stimulating factor in a canine model of bacterial sepsis. J. Appl. Physiol. 77:2366-2373.
6. Erlinger, S. 1996. New insights into the mechanism of hepatic transport and bile secretion. J. Gastroenterol. Hepatol. 11:575-579.
7. Ganzinger, U., A. Haslberger, H. Schiel, R. Omilian-Rosso, and E. Schutze. 1986. Influence of endotoxin on the distribution of cephalosporins in rabbits. J. Antimicrob. Chemother. 17:785-793.
8. Gorgen, I., T. Hartung, M. Leist, M. Niehorster, G. Tiegs, S. Uhlig, F. Weitzel, and A. Wendel. 1992. Granulocyte colony-stimulating factor treatment protects rodents against lipopdysaccharide-induced toxicity via suppression of systemic tumor necrosis factor-α. J. Immunol. 149:918-924.
9. Green, R. M., D. Beier, and J. L. Gollan. 1996. Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in redents. Gastroenterology 111:193-198.
10. Haghgoo, S., T. Hasegawa, M. Nadai, L. Wang, T. Nabeshima, N. Kato. 1995. Effect of a bacterial lipopolysaccharide on biliary excretion of a β-lactam antibiotic, cefoperazone, in rats. Antimicrob. Agents Chemother. 39:2258-2261.
11. Hasegawa, T., M. Ohta, I. Nakashima, and N. Kato. 1983. The Klebsiella O3 lipopolysaccharide isolated from culture fluid: structure of the polysaccharide moiety. Microbiol. Immunol. 27:683-694.
12. -). Chem. Pharm. Bull. 33:333-339.
13. Hebert, J. C., M. O'Reilly, and R. L. Gamelli. 1990. Protective effect of recombinant human granulocyte colony-stimulating factor against Pneumococcal infections in splenectomized mice. Arch. Surg. 125:1073-1078.
14. Hewett, J. A., and R. A. Roth. 1993. Hepatic and extrahepatic pathobiology ot bacterial lipopolysaccharides. Pharmacol. Rev. 45:381-411.
15. Hewett, J. A., A. E. Schultze, S. VanCise, and R. A. Roth. 1992 Neutrophil depletion protects against liver injury from bacterial endotoxin. Lab. Invest. 55:347-361.
16. Hirata, K., A. Kaneko, K. Ogawa, H. Hayasaka, and T. Onoe. 1980. Effect of endotoxin on rat liver. Analysis of acid phosphatase isozymes in the liver of normal and endotoxin-treated rats. Lab. Invest. 43:165-171.
17. Lang, C. H., P. E. Molina, and N. N. Abumrad. 1993. Granulocyte colony-stimulating factor prevents ethanol-induced impairment in host defense in septic rats. Alcohol Clin. Exp. Res. 17:1268-1274.
18. Levy, E., F. C. Path, and B. H. Ruebner. 1967. Hepatic changes produced by a single dose of endotoxin in the mouse. Light microscopy and histochemistry. Am. J. Pathol. 51:269-285.
19. Lodefoged, O. 1977. Pharmacokinetics of trimethoprim (TMP) in normal and febrile rabbits. Acta Pharmacol. Toxicol. 41:507-514.
20. Lundblad, R., J. M. Nesland, and K.-E. Giercksky. 1996. Granulocyte colony-stimulating factor improves survival rate and reduces concentrations of bacteria, endotoxin, tumor necrosis factor, and endothelin-1 in fulminant intra-abdominal sepsis in rats. Crit. Care Med. 24:820-826.
21. Moselev, R. H., L. Jones, W. Wang, and H. Takeda. 1995. Further insights into the role of cytokines in sepsis-associated cholestasis. Hepatology 22: A317. (Abstract.)
22. Moseley, R. H., W. Wang, H. Takeda, K. Lown, L. Shick, M. Ananthanarayanan, and F. J. Suchy. 1996. Effect of endotoxin on bile acid transport in rat liver: a potential model for sepsis-associated cholestasis. Am. J. Physiol. 271: G137-G146.
23. Nadai, M., T. Hasegawa, K. Kato, L. Wang, T. Nabeshima, and N. Kato. 1993. The disposition and renal handling of enprofylline in endotoxemic rats by bacterial lipopolysaccharide (LPS). Drug Metab. Dispos. 21:611-616.
24. Nadai, M., T. Hasegawa, K. Kato, L. Wang, T. Nabeshima, and N. Kato. 1993. Alterations in the pharmacokinetics and protein binding behavior of cefazolin in endotoxemic rats. Antimicrob. Agents Chemother. 37:1781-1785.
25. Nadai, M., T. Hasegawa, K. Kato, L. Wang, T. Nabeshima, and N. Kato. 1993. Influence of a bacterial lipopolysaccharide on the pharmacokinetics of tobramycin in rats. J. Pharm. Pharmacol. 45:971-974.
26. Ohta, M., M. Mori, T. Hasegawa, F. Nagase, I. Nakashima, S. Naito, and N. Kato. 1981. Further studies of the polysaccharide of Klebsiella pneumoniae possessing strong adjuvanticity. I. Production of the adjuvant polysaccharide by noncapsulated mutant. Microbiol. Immunol. 25:939-948.
27. Raetz, C. R. H., R. Ulevitch, S. D. Wright, C. H. Sibley, A. Ding, and C. F. Nathan. 1991. Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction. FASEB J. 5:2652-2660.
28. Roelofsen, H., B. Schoemaker, C. Bakker, R. Ottenhoff, P. L. M. Jansen, and R. P. J. Oude Elferink. 1995. Impaired hepatocanalicular organic anion transport in endotoxemic rats. Am. J. Physiol. 269:G427-G434.
29. Sewer, M. B., D. R. Koop, and E. T. Morgan. 1996. Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450. Drug Melab. Dispos. 24:401-407.
30. Shedlofsky, S. I., B. C. Israel, C. J. McClain, D. B. Hill, and R. A. Blouin. 1994. Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism. J. Clin. Invest. 94:2209-2214.
31. Silver, G. M., R. L. Gamelli, and M. O'Reilly. 1989. The beneficial effect of granulocyte colony-stimulating factor (G-CSF) in combination with gentamicin on survival after Pseudomonas burn wound infection. Surgery 106:452-456.
32. Tamai, I., T. Maekawa, and A. Tsuji. 1990. Membrane potential-dependent and carrier-mediated transport of cefpiramide, a cephalosporin antibiotic, in canalicular rat liver plasma membrane vesicles. J. Pharmacol. Exp. Ther. 253: 537-544.
33. Terashima, T., K. Soejima, Y. Waki, H. Nakamura, S. Fujishima, Y. Suzuki, A. Ishizaka, and M. Kanazawa. 1995. Neutrophils activated by granulocyte colony-stimulating factor suppress tumor necrosis factor-α release from monocytes stimulated by endotoxin. Am. J. Respir. Cell. Mol. Biol. 13:69-73.
34. Trauner, M., C. Gartung, S. F. Schlosser, and J. L. Boyer. 1996. Role of nitric oxide in the transcriptional regulaton of the bile acid transporters in endotoxin-induced cholestasis. Gastroenterology 110:A1349. (Abstract.)
35. Utili, R., C. O. Abernathy, and H. J. Zimmerman. 1976. Cholestatic effects of Escherichia coli endotoxin on the isolated perfused rat liver. Gastroenterology 70:248-253.
36. Utili, R., C. O. Abernathy, and H. J. Zimmerman. 1977. Studies on the effects of E. coli endotoxin on canalicular bile formation in the isolated perfused rat liver. J. Lab. Clin. Med. 89:471-482.
37. +-adenosinetriphosphatase by endotoxin: a possible mechanism for endotoxin-induced cholestasis. J. Infect. Dis. 136:583-587.
38. Weiss, S. J. 1989. Tissue destruction by neutrophils. N. Engl. J. Med. 320: 365-376.
39. Whiting, J. F., R. M. Green, A. B. Rosenbluth, and J. Gollan. 1995. Tumor necrosis factor-alpha decreases hepatocyte bile salt uptake and mediates endotoxin-induced cholestasis. Hepatology 22:1273-1278.
40. Yamaoka, K., Y. Tanigawara, T. Nakagawa, and T. Uno. 1981. A pharmacokinetic analysis program (MULTI) for microcomputer. J. Pharmacobio.-Dyn. 4:879-885.