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Volumn 27, Issue 2 SUPPL. 1, 2004, Pages 119-126

P-glycoprotein expression affects the intracellular concentration and antiviral activity of the protease inhibitor saquinavir in a T cell line

Author keywords

HIV; P glycoprotein; Protease inhibitors

Indexed keywords

ANTIVIRUS AGENT; GLYCOPROTEIN P; NELFINAVIR; PROTEINASE INHIBITOR; SAQUINAVIR; VALSPODAR; VINBLASTINE;

EID: 19944426763     PISSN: 11217138     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (13)

References (39)
  • 1
    • 0026039087 scopus 로고
    • Prostaglandin A inhibits replication of human immunodeficiency virus during acute infection
    • ANKEL, H., TURRIZIANI, O. AND ANTONELLI, G. (1991). Prostaglandin A inhibits replication of human immunodeficiency virus during acute infection. Journal of General Virology, 72, 2797-2800.
    • (1991) Journal of General Virology , vol.72 , pp. 2797-2800
    • Ankel, H.1    Turriziani, O.2    Antonelli, G.3
  • 3
  • 5
    • 0018770071 scopus 로고
    • Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemia lymphoblast
    • BECK, W.T., MUELLER, T.J. AND TANZER, L.R. (1979). Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemia lymphoblast. Cancer Research, 39, 2070-2076.
    • (1979) Cancer Research , vol.39 , pp. 2070-2076
    • Beck, W.T.1    Mueller, T.J.2    Tanzer, L.R.3
  • 6
    • 0028608081 scopus 로고
    • Heterogeneity in P-glycoprotein (multidrug resistance) activity among murine peripheral T cells: Correlation with surface phenotype and effector function
    • BOMMHARDT, U., CEROTTINI, J.C, AND MACDONALD, H.R. (1994). Heterogeneity in P-glycoprotein (multidrug resistance) activity among murine peripheral T cells: correlation with surface phenotype and effector function. European Journal of Immunology, 24, 2974-2981.
    • (1994) European Journal of Immunology , vol.24 , pp. 2974-2981
    • Bommhardt, U.1    Cerottini, J.C.2    MacDonald, H.R.3
  • 7
    • 0030577119 scopus 로고    scopus 로고
    • P-glycoprotein multidrug resistance and cancer
    • BOSCH, I. AND CROOP, J. (1996). P-glycoprotein multidrug resistance and cancer. Biochimica et Biophysica Acta, 1288 (2), F37-F54.
    • (1996) Biochimica et Biophysica Acta , vol.1288 , Issue.2
    • Bosch, I.1    Croop, J.2
  • 10
    • 0028177656 scopus 로고
    • Identification of a linear human-specific epitope in the fourth loop of the P-glycoprotein extracellular domain by MM4.17 murine monoclonal antibody to human multi-drug-resistant cells
    • CIANFRIGLIA, M., WILLINGHAM, M.C., TOMBESI, M., SCAGLIOTTI, G.V., FRASCA, G. AND CHERSI, A. (1994). Identification of a linear human-specific epitope in the fourth loop of the P-glycoprotein extracellular domain by MM4.17 murine monoclonal antibody to human multi-drug-resistant cells. International Journal of Cancer, 56, 153-160.
    • (1994) International Journal of Cancer , vol.56 , pp. 153-160
    • Cianfriglia, M.1    Willingham, M.C.2    Tombesi, M.3    Scagliotti, G.V.4    Frasca, G.5    Chersi, A.6
  • 13
    • 0033000454 scopus 로고    scopus 로고
    • Absolute quantitation of MDR1 transcripts using heterologous DNA standards-validation of the competitive RT-PCR (CRT-PCR) approach
    • EL-OSTA, A., KANTHARIDIS, P. AND ZALCBERG, J. (1999). Absolute quantitation of MDR1 transcripts using heterologous DNA standards-validation of the competitive RT-PCR (CRT-PCR) approach. Bio Techniques, 26, 1114-1124.
    • (1999) Bio Techniques , vol.26 , pp. 1114-1124
    • El-Osta, A.1    Kantharidis, P.2    Zalcberg, J.3
  • 15
    • 0025145490 scopus 로고
    • Human immunodeficiency virus 1-induced expression of P-glycoprotein
    • GOLLAPUDI, S. AND GUPTA, S. (1990). Human immunodeficiency virus 1-induced expression of P-glycoprotein. Biochemical Biophysical Research Communications, 171, 1002-1007.
    • (1990) Biochemical Biophysical Research Communications , vol.171 , pp. 1002-1007
    • Gollapudi, S.1    Gupta, S.2
  • 16
    • 0345139075 scopus 로고
    • Functional role for the 170 to 180-Kda glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies
    • HAMADA, H. AND TSURUO, T. (1986). Functional role for the 170 to 180-Kda glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. Proceedings of the National Academy of Sciences of the USA, 83, 7785-7789.
    • (1986) Proceedings of the National Academy of Sciences of the USA , vol.83 , pp. 7785-7789
    • Hamada, H.1    Tsuruo, T.2
  • 17
    • 0024346229 scopus 로고
    • Evaluation of new antiviral agents: In vitro perspectives
    • Hu, J.M. AND HSIUNG, G.D. (1989). Evaluation of new antiviral agents: in vitro perspectives. Antiviral Research, 11, 217-232.
    • (1989) Antiviral Research , vol.11 , pp. 217-232
    • Hu, J.M.1    Hsiung, G.D.2
  • 18
    • 0035853376 scopus 로고    scopus 로고
    • Differences in the intracellular uptake of HIV protease inhibitors in vitro and the effect of active transport
    • JONES, K., HOGGARD, P.G., SALES, S.D., KHOO, S., DAVEY, R. AND BACK, D.J. (2001a). Differences in the intracellular uptake of HIV protease inhibitors in vitro and the effect of active transport. AIDS, 15, 675-681.
    • (2001) AIDS , vol.15 , pp. 675-681
    • Jones, K.1    Hoggard, P.G.2    Sales, S.D.3    Khoo, S.4    Davey, R.5    Back, D.J.6
  • 19
    • 0035958776 scopus 로고    scopus 로고
    • P-glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: Potential for accelerated viral drug resistance?
    • JONES, K., BRAY, P.G., KHOO, S.H., DAVEY, R.A., MEADEN, E.R., WARD, S.A. AND BACK, D.J. (2001b). P-glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance? AIDS, 15, 1353-1358.
    • (2001) AIDS , vol.15 , pp. 1353-1358
    • Jones, K.1    Bray, P.G.2    Khoo, S.H.3    Davey, R.A.4    Meaden, E.R.5    Ward, S.A.6    Back, D.J.7
  • 20
    • 0020578356 scopus 로고
    • Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines
    • KARTNER, N., RIORDAN, J.R. AND LING, V. (1983). Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science, 221, 1285-1288.
    • (1983) Science , vol.221 , pp. 1285-1288
    • Kartner, N.1    Riordan, J.R.2    Ling, V.3
  • 21
    • 0028283511 scopus 로고
    • Identification of a P-glycoprotein-related protein (mini-P-glycoprotein) which is overexpressed in multidrug resistant cells
    • KAWAI, K., KUSANO, I., IDO, M., SAKURAI, M., SHIRAISHI, T. AND VATANI, R. (1994). Identification of a P-glycoprotein-related protein (mini-P- glycoprotein) which is overexpressed in multidrug resistant cells. Biochemical and Biophysical Research Communications, 198, 804-810.
    • (1994) Biochemical and Biophysical Research Communications , vol.198 , pp. 804-810
    • Kawai, K.1    Kusano, I.2    Ido, M.3    Sakurai, M.4    Shiraishi, T.5    Vatani, R.6
  • 23
    • 0032518290 scopus 로고    scopus 로고
    • The drug transporter P glycoprotein limits oral absorption and brain entry of HIV-1 proteinase inhibitors
    • KIM, R.B., FROMM, M.F., WANDEL, C., LEAKE, B., WOOD, A.J.J. AND RODEN, D.M. (1998). The drug transporter P glycoprotein limits oral absorption and brain entry of HIV-1 proteinase inhibitors. Journal of Clinical Investigations, 101, 289-294.
    • (1998) Journal of Clinical Investigations , vol.101 , pp. 289-294
    • Kim, R.B.1    Fromm, M.F.2    Wandel, C.3    Leake, B.4    Wood, A.J.J.5    Roden, D.M.6
  • 24
    • 0034057157 scopus 로고    scopus 로고
    • Effect of ABC transporters on HIV-1 infection: Inhibition of virus production by the MDR1 transporter
    • LEE, C.G.L, RAMACHANDRA, M., JEANG, K-T., MARTIN, M.A., PASTAN, I. AND GOTTESMAN, M.M., (2000). Effect of ABC transporters on HIV-1 infection: inhibition of virus production by the MDR1 transporter. FASEB Journal, 14, 516-522.
    • (2000) FASEB Journal , vol.14 , pp. 516-522
    • Lee, C.G.L.1    Ramachandra, M.2    Jeang, K.-T.3    Martin, M.A.4    Pastan, I.5    Gottesman, M.M.6
  • 25
    • 0028978727 scopus 로고
    • Transmembrane P-glycoprotein (P-gp/P-170) in HIV infection: Analysis of lymphocyte surface expression and drug-unrelated function
    • LUCIA, M.B., CAUDA, R., LANDAY, A.L., MALORNI, W., DONELLI, G. AND ORTONA, L. (1995). Transmembrane P-glycoprotein (P-gp/P-170) in HIV infection: analysis of lymphocyte surface expression and drug-unrelated function. AIDS Research and Human Retroviruses 11, 893-901.
    • (1995) AIDS Research and Human Retroviruses , vol.11 , pp. 893-901
    • Lucia, M.B.1    Cauda, R.2    Landay, A.L.3    Malorni, W.4    Donelli, G.5    Ortona, L.6
  • 26
    • 0031802858 scopus 로고    scopus 로고
    • Differential activity of P-glycoprotein in normal blood lymphocytes subsets
    • LUDESCHER, C., PALL, G., IRSCHICK, E.U., AND GASTL, G. (1998). Differential activity of P-glycoprotein in normal blood lymphocytes subsets. British Journal of Haematology, 101, 722-727.
    • (1998) British Journal of Haematology , vol.101 , pp. 722-727
    • Ludescher, C.1    Pall, G.2    Irschick, E.U.3    Gastl, G.4
  • 27
    • 0032963635 scopus 로고    scopus 로고
    • In vitro translation of a 2.3-kb splicing variant of the hamster pgp1 gene whose presence in transfectants is associated with decreased drug resistance
    • MA, J.E., GRANT, G., STAELENS, B., HOWARD, D.L. AND MELERA, P.W. (1999). In vitro translation of a 2.3-kb splicing variant of the hamster pgp1 gene whose presence in transfectants is associated with decreased drug resistance. Cancer Chemotherapy and Pharmacology, 43, 19-28.
    • (1999) Cancer Chemotherapy and Pharmacology , vol.43 , pp. 19-28
    • Ma, J.E.1    Grant, G.2    Staelens, B.3    Howard, D.L.4    Melera, P.W.5
  • 28
    • 0034764807 scopus 로고    scopus 로고
    • Expression of p-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected individuals
    • MEADEN, E.R., HOGGARD, P.G., MAHER, B., KHOO, S.H. AND BACK, D.J. (2001). Expression of p-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected individuals. AIDS Research and Human Retroviruses, 17, 1329-1332.
    • (2001) AIDS Research and Human Retroviruses , vol.17 , pp. 1329-1332
    • Meaden, E.R.1    Hoggard, P.G.2    Maher, B.3    Khoo, S.H.4    Back, D.J.5
  • 29
    • 0033946706 scopus 로고    scopus 로고
    • Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture
    • PERLOFF, M.D., VON MOLTKE L.L., FAHEY, J.M., DAILY, J.P. AND GREEBLATT, D.J. (2000). Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture. AIDS, 14, 1287-1289.
    • (2000) AIDS , vol.14 , pp. 1287-1289
    • Perloff, M.D.1    Von Moltke, L.L.2    Fahey, J.M.3    Daily, J.P.4    Greeblatt, D.J.5
  • 30
    • 0032834195 scopus 로고    scopus 로고
    • Interferon-γ upregulates P-glycoprotein expression in human peripheral blood monocyte-derived macrophages
    • PUDDU, P., GHERARDI, G., FAIS, S., LUCANI, F., ROMAGNOLI, G., CIANFRUGLIA, M. AND GESSANI, S. (1999). Interferon-γ upregulates P-glycoprotein expression in human peripheral blood monocyte-derived macrophages. Laboratory Investigation, 79, 1299-1309.
    • (1999) Laboratory Investigation , vol.79 , pp. 1299-1309
    • Puddu, P.1    Gherardi, G.2    Fais, S.3    Lucani, F.4    Romagnoli, G.5    Cianfruglia, M.6    Gessani, S.7
  • 32
    • 0031788927 scopus 로고    scopus 로고
    • Human immunodeficiency virus protease-inhibitors serve as substrate for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters
    • SRINIVAS, R.V., MIDDLEMAS, D., FLYNN, P. AND FRIDLAND, A. (1998). Human immunodeficiency virus protease-inhibitors serve as substrate for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters. Antimicrobial Agents & Chemotherapy, 42, 3157-3162.
    • (1998) Antimicrobial Agents & Chemotherapy , vol.42 , pp. 3157-3162
    • Srinivas, R.V.1    Middlemas, D.2    Flynn, P.3    Fridland, A.4
  • 33
    • 0030044189 scopus 로고    scopus 로고
    • Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by an approximately 80-kDa MDR1a gene product
    • THÉVENOD, F., HILDEBRANDT, J.P., STRIESSING, J., DE JONGE, H.R. AND SCHULZ, I. (1996). Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by an approximately 80-kDa MDR1a gene product. Journal of Biological Chemistry, 271, 3300-3305.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 3300-3305
    • Thévenod, F.1    Hildebrandt, J.P.2    Striessing, J.3    De Jonge, H.R.4    Schulz, I.5
  • 34
    • 0034939981 scopus 로고    scopus 로고
    • Evidence that natural killer cells express mini P-glycoproteins but not classic 170 kDa P-glycoprotein
    • TRAMBAS, C., WANG, Z., CIANFRIGLIA, M. & WOODS, G. (2001). Evidence that natural killer cells express mini P-glycoproteins but not classic 170 kDa P-glycoprotein. British Journal of Haematology, 114, 177-184.
    • (2001) British Journal of Haematology , vol.114 , pp. 177-184
    • Trambas, C.1    Wang, Z.2    Cianfriglia, M.3    Woods, G.4
  • 35
    • 0033966185 scopus 로고    scopus 로고
    • May the drug transporter P glycoprotein affect the antiviral activity of human immunodeficiency virus type 1 proteinase inhibitors?
    • TURRIZIANI, O., DI MARCO P., ANTONELLI G. AND DIANZANI F. (2000) May the drug transporter P glycoprotein affect the antiviral activity of human immunodeficiency virus type 1 proteinase inhibitors? Antimicrobial Agents & Chemotherapy, 44, 473-747.
    • (2000) Antimicrobial Agents & Chemotherapy , vol.44 , pp. 473-747
    • Turriziani, O.1    Di Marco, P.2    Antonelli, G.3    Dianzani, F.4
  • 38
    • 0032710406 scopus 로고    scopus 로고
    • The steady-state plasma pharmacokinetics of indinavir alone and in combination with a low dose of ritonavir in twice daily dosing regimens in HIV-1 infected individuals
    • VAN HEESWIJK, RP, VELDKAMP, AI, HOETELMANS, RM, MULDER, JW, SCHREIJ, G, HSU, A, LANGE, JM, BEIJNEN, JH, AND MEENHORST, PL. (1999) The steady-state plasma pharmacokinetics of indinavir alone and in combination with a low dose of ritonavir in twice daily dosing regimens in HIV-1 infected individuals. AIDS, 13 (14):F95-99.
    • (1999) AIDS , vol.13 , Issue.14
    • Van Heeswijk, R.P.1    Veldkamp, A.I.2    Hoetelmans, R.M.3    Mulder, J.W.4    Schreij, G.5    Hsu, A.6    Lange, J.M.7    Beijnen, J.H.8    Meenhorst, P.L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.