RAMP2 and RAMP3 mRNA levels are increased in failing rat cardiomyocytes and associated with increased responsiveness to adrenomedullin

Journal of Molecular and Cellular Cardiology

Volumn 38, Issue 1, 2005, Pages 145-151

  Øie, Erik ^a,b,d   Vinge, Leif Erik ^b   Andersen, Geir Øystein ^a   Yndestad, Arne ^c   Krobert, Kurt A ^a   Sandberg, Cecilie ^a,b   Ahmed, Mohammed Shakil ^b   Haug, Terje ^a   Levy, Finn Olav ^a   Skomedal, Tor ^a   Attramadal, Håvard ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b Rikshosp Univ Hosp N 0027 O   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

^d DIAKONHJEMMET HOSPITAL   (Norway)

Author keywords

Adrenomedullin; Cardiomyocytes; Heart failure; RAMP

Indexed keywords

ADENYLATE CYCLASE; ADRENOMEDULLIN; ADRENOMEDULLIN RECEPTOR; CHAPERONE; MESSENGER RNA; RECEPTOR ACTIVITY MODIFYING PROTEIN; RECEPTOR ACTIVITY MODIFYING PROTEIN 2; RECEPTOR ACTIVITY MODIFYING PROTEIN 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CELL ISOLATION; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; FIBROBLAST; HEART INFARCTION; HEART MUSCLE CELL; IMMUNOREACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; RECEPTOR BINDING;

ADRENOMEDULLIN; ANIMALS; GENE EXPRESSION REGULATION; HEART; HEART FAILURE, CONGESTIVE; HEMODYNAMIC PROCESSES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG; MALE; MEMBRANE PROTEINS; MYOCARDIUM; ORGAN SIZE; PEPTIDES; RATS; RATS, WISTAR; RECEPTORS, PEPTIDE; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 19944405740     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2004.10.009     Document Type: Article

References (28)

1. J.P. Hinson, S. Kapas, and D.M. Smith Adrenomedullin, a multifunctional regulatory peptide Endocr. Rev. 21 2000 138 167
2. K. Kitamura, K. Kangawa, M. Kawamoto, Y. Ichiki, S. Nakamura, and H. Matsuo Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma Biochem. Biophys. Res. Commun. 192 1993 553 560
3. T. Ebara, K. Miura, M. Okumura, T. Matsuura, S. Kim, and T. Yukimura Effect of adrenomedullin on renal hemodynamics and functions in dogs Eur. J. Pharmacol. 263 1994 69 73
4. E. Øie, L.E. Vinge, A. Yndestad, C. Sandberg, H.K. Grøgaard, and H. Attramadal Induction of a myocardial adrenomedullin signaling system during ischemic heart failure in rats Circulation 101 2000 415 422
5. T. Tsuruda, J. Kato, K. Kitamura, K. Kuwasako, T. Imamura, and Y. Koiwaya Adrenomedullin: a possible autocrine or paracrine inhibitor of hypertrophy of cardiomyocytes Hypertension 31 1998 505 510
6. P. Niu, T. Shindo, H. Iwata, A. Ebihara, Y. Suematsu, and Y. Zhang Accelerated cardiac hypertrophy and renal damage induced by angiotensin II in adrenomedullin knockout mice Hypertens. Res. 26 2003 731 736
7. H. Okumura, N. Nagaya, T. Itoh, I. Okano, J. Hino, and K. Mori Adrenomedullin infusion attenuates myocardial ischemia/reperfusion injury through the phosphatidylinositol 3-kinase/Akt-dependent pathway Circulation 109 2004 242 248
8. L.M. McLatchie, N.J. Fraser, M.J. Main, A. Wise, J. Brown, and N. Thompson RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor Nature 393 1998 333 339
9. B.N. Evans, M.I. Rosenblatt, L.O. Mnayer, K.R. Oliver, and I.M. Dickerson CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors J. Biol. Chem. 275 2000 31438 31443
10. E. Øie, L.E. Vinge, T. Tønnessen, H.K. Grøgaard, H. Kjekshus, and G. Christensen Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA during congestive heart failure in rats Am. J. Physiol. 273 1997 H1727 H1736
11. M.B. De Young, B. Giannattasio, and A. Scarpa Isolation of calcium-tolerant atrial and ventricular myocytes from adult rat heart Methods Enzymol. 173 1989 662 676
12. H. Viko, J.B. Osnes, A.E. Sjetnan, and T. Skomedal Improved isolation of cardiomyocytes by trypsination in addition to collagenase treatment Pharmacol. Toxicol. 76 1995 68 71
13. K.A. Krobert, T. Bach, T. Syversveen, A.M. Kvingedal, and F.O. Levy The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution Naunyn Schmiedebergs Arch. Pharmacol. 363 2001 620 632
14. Y. Salomon, C. Londos, and M. Rodbell A highly sensitive adenylate cyclase assay Anal. Biochem. 58 1974 541 548
15. L. Birnbaumer, P.C. Yang, M. Hunzicker-Dunn, J. Bockaert, and J.M. Duran Adenylyl cyclase activities in ovarian tissues. I. Homogenization and conditions of assay in graafian follicles and corpora lutea of rabbits, rats, and pigs: regulation by ATP, and some comparative properties Endocrinology 99 1976 163 184
16. S. Kapas, K.J. Catt, and A.J. Clark Cloning and expression of cDNA encoding a rat adrenomedullin receptor J. Biol. Chem. 270 1995 25344 25347
17. S. Kapas, and A.J. Clark Identification of an orphan receptor gene as a type 1 calcitonin gene-related peptide receptor Biochem. Biophys. Res. Commun. 217 1995 832 838
18. S.P. Kennedy, D. Sun, J.J. Oleynek, C.F. Hoth, J. Kong, and R.J. Hill Expression of the rat adrenomedullin receptor or a putative human adrenomedullin receptor does not correlate with adrenomedullin binding or functional response Biochem. Biophys. Res. Commun. 244 1998 832 837
19. M. Heesen, M.A. Berman, A. Charest, D. Housman, C. Gerard, and M.E. Dorf Cloning and chromosomal mapping of an orphan chemokine receptor: mouse RDC1 Immunogenetics 47 1998 364 370
20. Y. Tomoda, K. Kikumoto, Y. Isumi, T. Katafuchi, A. Tanaka, and K. Kangawa Cardiac fibroblasts are major production and target cells of adrenomedullin in the heart in vitro Cardiovasc. Res. 49 2001 721 730
21. K. Totsune, K. Takahashi, H.S. Mackenzi, O. Murakami, Z. Arihara, and M. Sone Increased gene expression of adrenomedullin and adrenomedullin-receptor complexes, receptor-activity-modifying protein (RAMP)2 and calcitonin-receptor- like receptor (CRLR) in the hearts of rats with congestive heart failure Clin. Sci. 99 2000 541 546
22. I. Szokodi, P. Kinnunen, P. Tavi, M. Weckstrom, M. Toth, and H. Ruskoaho Evidence for cAMP-independent mechanisms mediating the effects of adrenomedullin, a new inotropic peptide Circulation 97 1998 1062 1070
23. H. Hayakawa, Y. Hirata, M. Kakoki, Y. Suzuki, H. Nishimatsu, and D. Nagata Role of nitric oxide-cGMP pathway in adrenomedullin-induced vasodilation in the rat Hypertension 33 1999 689 693
24. T. Tsuruda, J. Kato, K. Kitamura, T. Imamura, Y. Koiwaya, and K. Kangawa Enhanced adrenomedullin production by mechanical stretching in cultured rat cardiomyocytes Hypertension 35 2000 1210 1214
25. S. Cormier-Regard, S.V. Nguyen, and W.C. Claycomb Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes J. Biol. Chem. 273 1998 17787 17792
26. K. Mishima, J. Kato, K. Kuwasako, K. Ito, T. Imamura, and K. Kitamura Effects of endothelin on adrenomedullin secretion and expression of adrenomedullin receptors in rat cardiomyocytes Biochem. Biophys. Res. Commun 287 2001 264 269
27. T. Horio, T. Nishikimi, F. Yoshihara, N. Nagaya, H. Matsuo, and S. Takishita Production and secretion of adrenomedullin in cultured rat cardiac myocytes and nonmyocytes: stimulation by interleukin-1beta and tumor necrosis factor-alpha Endocrinology 139 1998 4576 4580
28. T. Horio, T. Nishikimi, F. Yoshihara, H. Matsuo, S. Takishita, and K. Kangawa Effects of adrenomedullin on cultured rat cardiac myocytes and fibroblasts Eur. J. Pharmacol. 382 1999 1 9