Role of nitric oxide-cGMP pathway in adrenomedullin-induced vasodilation in the rat

Hypertension

Volumn 33, Issue 2, 1999, Pages 689-693

  Hayakawa, Hiroshi ^a   Hirata, Yasunobu ^b   Kakoki, Masao ^b   Suzuki, Yasuko ^b   Nishimatsu, Hiroaki ^b   Nagata, Daisuke ^b   Suzuki, Etsu ^b   Kikuchi, Kazuya ^a   Nagano, Tetsuo ^a   Kangawa, Kenji ^c   Matsuo, Hisayuki ^c   Sugimoto, Tsuneaki ^a   Omata, Masao ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Adrenomedullin; Cyclic GMP; Endothelium; Nitric oxide; Phosphodiesterase inhibitors; Rats

Indexed keywords

ACETYLCHOLINE; ADRENOMEDULLIN; CYCLIC GMP; NITRIC OXIDE; PHOSPHODIESTERASE INHIBITOR;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR AUTOREGULATION; CONTROLLED STUDY; ISOLATED KIDNEY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THORACIC AORTA; VASCULAR ENDOTHELIUM;

EID: 0033038382     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.33.2.689     Document Type: Article

References (30)

1. Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, Eto T. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun. 1993;192: 553-560.
2. Eguchi S, Hirata Y, Iwasaki H, Sato K, Watanabe TX, Inui T, Nakajima K, Sakakibara S, Marumo F. Structure-activity relationship of adrenomedullin, a novel vasodilatory peptide, in cultured rat vascular smooth muscle cells. Endocrinology. 1994;135:2454-2458.
3. Ishizaka Y, Ishizaka Y, Tanaka M, Kitamura K, Kangawa K, Minamino N, Matsuo H, Eto T. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. Biochem Biophys Res Commun. 1994; 200:642-646.
4. Kohno M, Yokokawa K, Yasunari K, Kano H, Horio T, Takeda T. Stimulation of cyclic adenosine monophosphate formation by the novel vasorelaxant peptide adrenomedullin in cultured rat mesangial cells. Metabolism. 1995;44:10-12.
5. 2+ mobilization, in bovine aonic endothelial cells. J Biol Chem. 1995;270:4412-4417.
6. Hirata Y, Hayakawa H, Suzuki Y, Suzuki E, Ikenouchi H, Kohmoto O, Kimura K, Kitamura K, Eto T, Kangawa K, Matsuo H, Omata M. Mechanisms of adrenomedullin-induced vasodilation in the rat kidney. Hypertension. 1995;25:790-795.
7. G-nitro L-arginine but not glibenclamide. Br J Pharmacol. 1995;115: 917-924.
8. Majid DS, Kadowitz PJ, Coy DH, Navar LG. Renal responses to intraarterial administration of adrenomedullin in dogs. Am J Physiol. 1996;270: F200-F205.
9. Baskaya MK, Suzuki Y, Anzai M, Seki Y, Saito K, Takayasu M, Shibuya M, Sugita K. Effects of adrenomedullin, calcitonin gene-related peptide, and amylin on cerebral circulation in dogs. J Cereb Blood Flow Metab. 1995;15:827-834.
10. Champion HC, Santiago JA, Murphy WA, Coy DH, Kadowitz PJ. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. Am J Physiol. 1997;272:R234-R242.
11. Thusu KG, Morin FC III, Russell JA, Steinhorn RH. The cGMP phosphodiesterase inhibitor zaprinast enhances the effect of nitric oxide. Am J Respir Crit Care Med. 1995;152:1605-1610.
12. Cohen AH, Hanson K, Morris K, Fouty B, McMurty IF, Clarke W, Rodman DM. Inhibition of cyclic 3′-5′-guanosine monophosphate-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats. J Clin Invest. 1996;97:172-179.
13. Saeki T, Adachi H, Takase Y, Yoshitake S, Souda S, Saito I. A selective type V phosphodiesterase inhibitor, E4021, dilates porcine large coronary artery. J Pharmacol Exp Ther. 1995;272:825-831.
14. Hayakawa H, Coffee K, Raij L. Endothelial dysfunction and cardiorenal injury in experimental salt sensitive hypertension: effects of antihypertensive therapy. Circulation. 1997;96:2407-2413.
15. Hirata Y, Hayakawa H, Suzuki E, Kimura K, Kikuchi K, Nagano T, Hirobe M, Omata M. Direct measurements of endothelium-derived nitric oxide release by stimulation of endothelin receptors in rat kidney and its alteration in salt-induced hypertension. Circulation. 1995;91:1229-1235.
16. 2 chemiluminescence method. J Biol Chem. 1993;268:23106-23110.
17. Osajima A, Mutoh Y, Uezono Y, Kawamura M, Izumi F, Takasugi M, Kuroiwa A. Adrenomedullin increases cyclic AMP more potently than CGRP and amylin in rat renal tubular basolateral membranes. Life Sci. 1995;57:457-462.
18. Kalo J, Kitamura K, Kangawa K, Eto T. Receptors for adrenomedullin in human vascular endothelial cells. Eur J Pharmacol. 1995;289:383-385.
19. 2+ sensitivity in pig coronary arterial smooth muscle. Biochem Biophys Res Commun. 1995;212:572-579.
20. Craven PA, DeRubertis FR. Restoration of the responsiveness of purified guanylate cyclase to nitrosoguanidine, nitric oxide, and related activators by heme and hemeproteins: evidence for involvement of the paramagnetic nitrosyl-heme complex in enzyme activation. J Biol Chem. 1978;253: 8433-8443.
21. Gardiner SM, Kemp PA, March JE, Bennett T. Regional haemodynamic effects of human and rat adrenomedullin in conscious rats. Br J Pharmacol. 1995;114:584-591.
22. Heaton J, Lin B, Chang JK, Steinberg S, Hyman A, Lippton H. Pulmonary vasodilation to adrenomedullin: a novel peptide in humans. Am J Physiol. 1995;268:H2211-H2215.
23. Nishida K, Harrison DG, Navas JP, Fisher AA, Dockery SP, Uematsu M, Nerem RM, Alexander RW, Murphy TJ. Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. J Clin Invest. 1992;90:2092-2096.
24. Lamas S, Marsden PA, Li GK, Tempst P, Michel T. Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. Proc Natl Acad Sci USA. 1992;89: 6348-6352.
25. Kapas S, Catt KJ, Clark AJ. Cloning and expression of cDNA encoding a rat adrenomedullin receptor. J Biol Chem. 1995;270:25344-25347.
26. McLatchie L, Fraser N, Main J, Wise A, Brown J, Thompson N, Solan R, Lee M, Foord S. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature. 1998;393:333-339.
27. Guo J, Iida Klein A, Huang X, Abou Samra AB, Segre GV, Bringhurst FR. Parathyroid hormone (PTH)/PTH-related peptide receptor density modulates activation of phospholipase C and phosphate transport by PTH in LLC-PK1 cells. Endocrinology. 1995;136:3884-3891.
28. Force T, Bonventre JV, Flannery MR, Gorn AH, Yamin M, Goldring SR. A cloned porcine renal calcitonin receptor couples to adenylyl cyclase and phospholipase C. Am J Physiol. 1992;262:F1110-F1115.
29. Bolotina VM, Najibi S, Palacino JJ, Pagano PJ, Cohen RA. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature. 1994;368:850-853.
30. Boulanger C, Luscher TF. Release of endothelin from the porcine aorta: inhibition by endothelium-derived nitric oxide. J Clin Invest. 1990;85: 587-590.