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Volumn 20, Issue 6, 2004, Pages 429-437

Genetic and perinatal factors as risk for childhood type 1 diabetes

Author keywords

Autoimmunity; Blood incompatibility; Gestational infections; HLA; Islet autoantibodies; Transplacental transfer

Indexed keywords

AUTOANTIBODY; GLUTAMATE DECARBOXYLASE ANTIBODY; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; INSULIN ANTIBODY; PROTEIN TYROSINE PHOSPHATASE;

EID: 19944399061     PISSN: 15207552     EISSN: None     Source Type: Journal    
DOI: 10.1002/dmrr.506     Document Type: Review
Times cited : (58)

References (97)
  • 1
    • 0035197969 scopus 로고    scopus 로고
    • Autoimmune type 1 diabetes: Resolved and unresolved issues
    • Notkins AL, Lernmark AA.. Autoimmune type 1 diabetes: resolved and unresolved issues. J Clin Invest 2001; 108: 1247-1252.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1247-1252
    • Notkins, A.L.1    Lernmark, A.A.2
  • 2
    • 0032710530 scopus 로고    scopus 로고
    • Optimized autoantibody-based risk assessment in family members. Implications for future intervention trials
    • Bingley PJ, Williams AJ, Gale EA.. Optimized autoantibody-based risk assessment in family members. Implications for future intervention trials. Diabetes Care 1999; 22: 1796-1801.
    • (1999) Diabetes Care , vol.22 , pp. 1796-1801
    • Bingley, P.J.1    Williams, A.J.2    Gale, E.A.3
  • 3
    • 0041570654 scopus 로고    scopus 로고
    • Immunological markers in the diagnosis and prediction of autoimmune type 1a diabetes
    • Winter WE, Harris N, Schatz DA.. Immunological markers in the diagnosis and prediction of autoimmune type 1a diabetes. Clinical Diabetes 2002; 20: 183.
    • (2002) Clinical Diabetes , vol.20 , pp. 183
    • Winter, W.E.1    Harris, N.2    Schatz, D.A.3
  • 4
    • 0028584260 scopus 로고
    • Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives
    • Bingley PJ, Christie MR, Bonifacio E, et al. Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives. Diabetes 1994; 43: 1304-1310.
    • (1994) Diabetes , vol.43 , pp. 1304-1310
    • Bingley, P.J.1    Christie, M.R.2    Bonifacio, E.3
  • 5
    • 0036195687 scopus 로고    scopus 로고
    • Prevalence and fate of type 1 diabetes-associated autoantibodies in cord blood samples from newborn infants of non-diabetic mothers
    • Hämälainen AM, Ilonen J, Simell O, et al. Prevalence and fate of type 1 diabetes-associated autoantibodies in cord blood samples from newborn infants of non-diabetic mothers. Diabetes Metab Res Rev 2002; 18: 57-63.
    • (2002) Diabetes Metab. Res. Rev. , vol.18 , pp. 57-63
    • Hämälainen, A.M.1    Ilonen, J.2    Simell, O.3
  • 6
    • 0030695027 scopus 로고    scopus 로고
    • Prediction of IDDM in the general population: Strategies based on combinations of autoantibody markers
    • Bingley PJ, Bonifacio E, Williams AJK, Genovese S, Bottazzo GF, Gale EAM.. Prediction of IDDM in the general population: Strategies based on combinations of autoantibody markers. Diabetes 1997; 46 1701-1710.
    • (1997) Diabetes , vol.46 , pp. 1701-1710
    • Bingley, P.J.1    Bonifacio, E.2    Williams, A.J.K.3    Genovese, S.4    Bottazzo, G.F.5    Gale, E.A.M.6
  • 7
    • 0034047565 scopus 로고    scopus 로고
    • Stability of autoantibodies and their relation to genetic and metabolic markers of Type I diabetes in initially unaffected schoolchildren
    • [In Process Citation]. 498th centile. Subjects at risk for rapid progression to Type I diabetes have two or more AAbs at or greater than the 499. 458th centile, 2000
    • Kulmala P, Rahko J, Savola K, et al. Stability of autoantibodies and their relation to genetic and metabolic markers of Type I diabetes in initially unaffected schoolchildren [In Process Citation]. Diabetologia 2000; 43: 457-464. 498th centile. Subjects at risk for rapid progression to Type I diabetes have two or more AAbs at or greater than the 499. 458th centile, 2000.
    • (2000) Diabetologia , vol.43 , pp. 457-464
    • Kulmala, P.1    Rahko, J.2    Savola, K.3
  • 8
    • 0036514136 scopus 로고    scopus 로고
    • Successful prospective prediction of type 1 diabetes in schoolchildren through multiple defined autoantibodies: An 8-year follow-up of the Washington State Diabetes Prediction Study
    • LaGasse JM, Brantley MS, Leech NJ, et al. Successful prospective prediction of type 1 diabetes in schoolchildren through multiple defined autoantibodies: an 8-year follow-up of the Washington State Diabetes Prediction Study. Diabetes Care 2002; 25: 505-511.
    • (2002) Diabetes Care , vol.25 , pp. 505-511
    • LaGasse, J.M.1    Brantley, M.S.2    Leech, N.J.3
  • 9
    • 0036093287 scopus 로고    scopus 로고
    • The Karlsburg type 1 diabetes risk study of a normal schoolchild population: Association of beta-cell autoantibodies and human leukocyte antigen-DQB1 alleles in antibody-positive individuals
    • Schlosser M, Strebelow M, Wassmuth R, et al. The Karlsburg type 1 diabetes risk study of a normal schoolchild population: association of beta-cell autoantibodies and human leukocyte antigen-DQB1 alleles in antibody-positive individuals. J Clin Endocrinol Metab 2002; 87: 2254-2261.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 2254-2261
    • Schlosser, M.1    Strebelow, M.2    Wassmuth, R.3
  • 10
    • 0028237147 scopus 로고
    • Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease
    • Tuomilehto J, Zimmet P, Mackay IR, et al. Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease. Lancet 1994; 343: 1383-1385.
    • (1994) Lancet , vol.343 , pp. 1383-1385
    • Tuomilehto, J.1    Zimmet, P.2    Mackay, I.R.3
  • 11
    • 6844252928 scopus 로고    scopus 로고
    • Glutamate decarboxylase antibodies in non-diabetic pregnancies precedes insulin-dependent diabetes in the mother but not necessarily in the offspring
    • Ivarsson SA, Ackefors M, Carlsson A, et al. Glutamate decarboxylase antibodies in non-diabetic pregnancies precedes insulin-dependent diabetes in the mother but not necessarily in the offspring. Autoimmunity 1997; 26: 261-269.
    • (1997) Autoimmunity , vol.26 , pp. 261-269
    • Ivarsson, S.A.1    Ackefors, M.2    Carlsson, A.3
  • 12
    • 0024511641 scopus 로고
    • The Swedish Childhood Diabetes Study - Results from a nine year case register and one year case-referent study indicating that type 1 (insulin-dependent) diabetes mellitus is associated with both type 2 (non-insulin-dependent) diabetes mellitus and autoimmune disorders
    • Dahlquist G, Blom L, Tuvemo T, Nyström L, Sandström A, Wall S.. The Swedish Childhood Diabetes Study - results from a nine year case register and one year case-referent study indicating that type 1 (insulin-dependent) diabetes mellitus is associated with both type 2 (non-insulin-dependent) diabetes mellitus and autoimmune disorders. Diabetologia 1989; 32: 2-6.
    • (1989) Diabetologia , vol.32 , pp. 2-6
    • Dahlquist, G.1    Blom, L.2    Tuvemo, T.3    Nyström, L.4    Sandström, A.5    Wall, S.6
  • 15
    • 0015223187 scopus 로고
    • High frequency of diabetes mellitus in young adults with congenital rubella
    • Forrest JM, Menser MA, Burgess JA.. High frequency of diabetes mellitus in young adults with congenital rubella. Lancet 1971; ii: 332-334.
    • (1971) Lancet , vol.2 , pp. 332-334
    • Forrest, J.M.1    Menser, M.A.2    Burgess, J.A.3
  • 16
    • 0022032855 scopus 로고
    • Diabetes mellitus and autoimmunity in patients with congenital rubella syndrome
    • Ginsberg-Fellner F, Witt ME, Fedun B, et al. Diabetes mellitus and autoimmunity in patients with congenital rubella syndrome. Rev Infect Dis 1985; 7: 170-176.
    • (1985) Rev. Infect. Dis. , vol.7 , pp. 170-176
    • Ginsberg-Fellner, F.1    Witt, M.E.2    Fedun, B.3
  • 17
    • 0026623232 scopus 로고
    • A fifty-year follow-up of congenital rubella
    • McIntosh EDG, Menser MA.. A fifty-year follow-up of congenital rubella. Lancet 1992; 340: 414-415.
    • (1992) Lancet , vol.340 , pp. 414-415
    • McIntosh, E.D.G.1    Menser, M.A.2
  • 18
    • 0023892911 scopus 로고
    • Maternal rubella and the congenital rubella syndrome
    • Freij BJ, South MA, Sever JL.. Maternal rubella and the congenital rubella syndrome. Clin Perinatol 1988; 15: 247-257.
    • (1988) Clin. Perinatol. , vol.15 , pp. 247-257
    • Freij, B.J.1    South, M.A.2    Sever, J.L.3
  • 19
    • 0028949805 scopus 로고
    • Maternal enteroviral infection during pregnancy as a risk factor for childhood IDDM
    • Dahlquist G, Ivarsson S, Lindberg B, Forsgren M.. Maternal enteroviral infection during pregnancy as a risk factor for childhood IDDM. Diabetes 1995; 44: 408-413.
    • (1995) Diabetes , vol.44 , pp. 408-413
    • Dahlquist, G.1    Ivarsson, S.2    Lindberg, B.3    Forsgren, M.4
  • 20
    • 0030670808 scopus 로고    scopus 로고
    • Viruses and other perinatal exposures as initiating events for beta-cell destruction
    • Dahlquist GG.. Viruses and other perinatal exposures as initiating events for beta-cell destruction. Ann Med 1997; 29 413-417.
    • (1997) Ann. Med. , vol.29 , pp. 413-417
    • Dahlquist, G.G.1
  • 21
    • 20244384697 scopus 로고
    • A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM. Childhood Diabetes in Finland (DiMe) Study
    • Hyöty H, Hiltunen M, Knip M, et al. A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM. Childhood Diabetes in Finland (DiMe) Study. Diabetes 1995; 44: 652-657.
    • (1995) Diabetes , vol.44 , pp. 652-657
    • Hyöty, H.1    Hiltunen, M.2    Knip, M.3
  • 22
    • 0028791239 scopus 로고
    • Indications that maternal coxsackie B virus infection during pregnancy is a risk factor for childhood-onset IDDM
    • Dahlquist G, Frisk G, Ivarsson SA, Svanberg L, Forsgren M, Diderholm H.. Indications that maternal coxsackie B virus infection during pregnancy is a risk factor for childhood-onset IDDM. Diabetologia 1995; 38: 1371-1373.
    • (1995) Diabetologia , vol.38 , pp. 1371-1373
    • Dahlquist, G.1    Frisk, G.2    Ivarsson, S.A.3    Svanberg, L.4    Forsgren, M.5    Diderholm, H.6
  • 23
    • 0035702136 scopus 로고    scopus 로고
    • No evidence for an association of coxsackie virus infections during pregnancy and early childhood with development of islet autoantibodies in offspring of mothers or fathers with type 1 diabetes
    • Fuchtenbusch M, Irnstetter A, Jager G, Ziegler AG.. No evidence for an association of coxsackie virus infections during pregnancy and early childhood with development of islet autoantibodies in offspring of mothers or fathers with type 1 diabetes. J Autoimmun 2001; 17: 333-340.
    • (2001) J. Autoimmun. , vol.17 , pp. 333-340
    • Fuchtenbusch, M.1    Irnstetter, A.2    Jager, G.3    Ziegler, A.G.4
  • 25
    • 0020041033 scopus 로고
    • The incidence of diabetes mellitus in Swedish children 0-14 years of age
    • Dahlquist G, Gustavsson KH, Holmgren G, et al. The incidence of diabetes mellitus in Swedish children 0-14 years of age. Acta Pædiatr Scand 1982; 71: 7-14
    • (1982) Acta Pædiatr. Scand. , vol.71 , pp. 7-14
    • Dahlquist, G.1    Gustavsson, K.H.2    Holmgren, G.3
  • 26
    • 0022389143 scopus 로고
    • The epidemiology of diabetes in Swedish children 0-14 years old a six-year prospective study
    • Dahlquist G, Blom L, Holmgren G, et al. The epidemiology of diabetes in Swedish children 0-14 years old a six-year prospective study. Diabetologia 1985; 28: 802-808.
    • (1985) Diabetologia , vol.28 , pp. 802-808
    • Dahlquist, G.1    Blom, L.2    Holmgren, G.3
  • 28
    • 0034764673 scopus 로고    scopus 로고
    • Trends in the incidence of childhood-onset diabetes in Europe 1989-1998
    • Green A, Patterson CC. Trends in the incidence of childhood-onset diabetes in Europe 1989-1998. Diabetologia 2001; 44(Suppl 3): B3-B8.
    • (2001) Diabetologia , vol.44 , Issue.SUPPL. 3
    • Green, A.1    Patterson, C.C.2
  • 29
    • 18744397916 scopus 로고    scopus 로고
    • Type I diabetes in the 0-34 years group in Sweden
    • and The Swedish Childhood Diabetes Study G
    • Pundziute-Lycka A, Dahlquist G, Nyström L, et al. and The Swedish Childhood Diabetes Study G. Type I diabetes in the 0-34 years group in Sweden. Diabetologia 2002; 45: 783-791.
    • (2002) Diabetologia , vol.45 , pp. 783-791
    • Pundziute-Lycka, A.1    Dahlquist, G.2    Nyström, L.3
  • 30
    • 0036319041 scopus 로고    scopus 로고
    • Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes
    • Graham J, Hagopian WA, Kockum I, et al. Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes. Diabetes 2002; 51: 1346-1555.
    • (2002) Diabetes , vol.51 , pp. 1346-1555
    • Graham, J.1    Hagopian, W.A.2    Kockum, I.3
  • 31
    • 0034821661 scopus 로고    scopus 로고
    • Seven Regions of the Genome Show Evidence of Linkage to Type 1 Diabetes in a Consensus Analysis of 767 Multiplex Families
    • Cox NJ, Wapelhorst B, Morrison VA, et al. Seven Regions of the Genome Show Evidence of Linkage to Type 1 Diabetes in a Consensus Analysis of 767 Multiplex Families. Am J Hum Genet 2001; 69: 4.
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 4
    • Cox, N.J.1    Wapelhorst, B.2    Morrison, V.A.3
  • 32
    • 0035212224 scopus 로고    scopus 로고
    • A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: Identification of new loci with evidence of interactions
    • Nerup J, Pociot F. A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions. Am J Hum Genet 2001; 69: 1301-1313.
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 1301-1313
    • Nerup, J.1    Pociot, F.2
  • 33
    • 0029025699 scopus 로고
    • Age-dependent HLA genetic heterogeneity of IDDM in Japanese patients
    • Awata T, Hagura R, Urakami T, Kanazawa Y. Age-dependent HLA genetic heterogeneity of IDDM in Japanese patients. Diabetologia 1995; 38: 748-749.
    • (1995) Diabetologia , vol.38 , pp. 748-749
    • Awata, T.1    Hagura, R.2    Urakami, T.3    Kanazawa, Y.4
  • 34
    • 0027054460 scopus 로고
    • Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus
    • Caillat-Zucman A, Garchon H-J, Timsit J, et al. Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus. J Clin Invest 1992; 90: 2242-2250.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2242-2250
    • Caillat-Zucman, A.1    Garchon, H.-J.2    Timsit, J.3
  • 36
    • 0034702031 scopus 로고    scopus 로고
    • Evaluation of fine mapping strategies for a multifactorial disease locus: Systematic linkage and association analysis of IDDM1 in the HLA region on chromosome 6p21
    • Herr M, Dudbridge F, Zavattari P, et al. Evaluation of fine mapping strategies for a multifactorial disease locus: systematic linkage and association analysis of IDDM1 in the HLA region on chromosome 6p21. Hum Mol Genet 2000; 9: 1291-1301.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1291-1301
    • Herr, M.1    Dudbridge, F.2    Zavattari, P.3
  • 37
    • 0029166110 scopus 로고
    • The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci
    • Cucca F, Lampis R, Frau F, et al. The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci. Human Immunology 1995; 43: 301-308.
    • (1995) Human Immunology , vol.43 , pp. 301-308
    • Cucca, F.1    Lampis, R.2    Frau, F.3
  • 38
    • 0031024575 scopus 로고    scopus 로고
    • HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection
    • Undlien DE, Friede T, Rammensee HG, et al. HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection. Diabetes 1997; 46: 143-149.
    • (1997) Diabetes , vol.46 , pp. 143-149
    • Undlien, D.E.1    Friede, T.2    Rammensee, H.G.3
  • 39
    • 0031935660 scopus 로고    scopus 로고
    • Association between autoantibody markers and subtypes of DR4 and DR4-DQ in Swedish children with insulin-dependent diabetes reveals closer association of tyrosine pyrophosphatase autoimmunity with DR4 than DQ8
    • Sanjeevi CB, Hagopian WA, Landin-Olsson M, et al. Association between autoantibody markers and subtypes of DR4 and DR4-DQ in Swedish children with insulin-dependent diabetes reveals closer association of tyrosine pyrophosphatase autoimmunity with DR4 than DQ8. Tissue Antigens 1998; 51: 281-286.
    • (1998) Tissue Antigens , vol.51 , pp. 281-286
    • Sanjeevi, C.B.1    Hagopian, W.A.2    Landin-Olsson, M.3
  • 40
    • 0033358374 scopus 로고    scopus 로고
    • The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene
    • Lie BA, Todd JA, Pociot F, et al. The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am J Hum Genet 1999; 64: 793-800.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 793-800
    • Lie, B.A.1    Todd, J.A.2    Pociot, F.3
  • 41
    • 0025331496 scopus 로고
    • Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus
    • Baisch JM, Weeks T, Giles R, Hoover M, Stastny P, Capra JD. Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus. N Engl J Med 1990; 322: 1836-1882.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1836-1882
    • Baisch, J.M.1    Weeks, T.2    Giles, R.3    Hoover, M.4    Stastny, P.5    Capra, J.D.6
  • 42
    • 0032964464 scopus 로고    scopus 로고
    • Negative association between type 1 diabetes and HLA DQB1*0602- DQA1*0102 is attenuated with age at onset
    • Swedish Childhood Diabetes Study Group
    • Graham J, Kockum I, Sanjeevi CB, et al. Negative association between type 1 diabetes and HLA DQB1*0602- DQA1* 0102 is attenuated with age at onset. Swedish Childhood Diabetes Study Group. Eur J Immunogenet 1999; 26: 117-127.
    • (1999) Eur. J. Immunogenet. , vol.26 , pp. 117-127
    • Graham, J.1    Kockum, I.2    Sanjeevi, C.B.3
  • 43
    • 0031847856 scopus 로고    scopus 로고
    • Screening for genetic IDDM risk and prevention trials in infancy
    • Ilonen J, Simell O, Knip M, Åkerblom HK. Screening for genetic IDDM risk and prevention trials in infancy. Diabetes Metab Rev 1998; 14: 188-189.
    • (1998) Diabetes Metab. Rev. , vol.14 , pp. 188-189
    • Ilonen, J.1    Simell, O.2    Knip, M.3    Åkerblom, H.K.4
  • 44
    • 0036775166 scopus 로고    scopus 로고
    • Natural history of beta-cell autoimmunity in young children with increased genetic susceptibility to type 1 diabetes recruited from the general population
    • Kimpimaki T, Kulmala P, Savola K, et al. Natural history of beta-cell autoimmunity in young children with increased genetic susceptibility to type 1 diabetes recruited from the general population. J Clin Endocrinol Metab 2002; 87: 4572-4579.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 4572-4579
    • Kimpimaki, T.1    Kulmala, P.2    Savola, K.3
  • 45
    • 0036197220 scopus 로고    scopus 로고
    • Identification of Children with Early Onset and High Incidence of Anti-islet Autoantibodies
    • Robles DT, Eisenbarth GS, Wang T, et al. Identification of Children with Early Onset and High Incidence of Anti-islet Autoantibodies. Clin Immunol 2002; 102: 217-224.
    • (2002) Clin. Immunol. , vol.102 , pp. 217-224
    • Robles, D.T.1    Eisenbarth, G.S.2    Wang, T.3
  • 46
    • 17944381519 scopus 로고    scopus 로고
    • The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: The Finnish Type 1 Diabetes Prediction and Prevention Study
    • Kimpimaki T, Kupila A, Hämälainen AM, et al. The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study. J Clin Endocrinol Metab 2001; 86: 4782-4788.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 4782-4788
    • Kimpimaki, T.1    Kupila, A.2    Hämälainen, A.M.3
  • 47
    • 0025995314 scopus 로고
    • The Swedish Childhood Diabetes Study - A multivariate analysis of risk determinants for diabetes in different age groups
    • Dahlquist G, Blom L, Lönnberg G. The Swedish Childhood Diabetes Study - a multivariate analysis of risk determinants for diabetes in different age groups. Diabetologia 1991; 34: 757-762.
    • (1991) Diabetologia , vol.34 , pp. 757-762
    • Dahlquist, G.1    Blom, L.2    Lönnberg, G.3
  • 48
    • 0028297290 scopus 로고
    • Long-term risk of IDDM in first-degree relatives of patients with IDDM
    • Lorenzen T, Pociot E, Hougaard P, Nerup J. Long-term risk of IDDM in first-degree relatives of patients with IDDM. Diabetologia 1994; 37: 321-327.
    • (1994) Diabetologia , vol.37 , pp. 321-327
    • Lorenzen, T.1    Pociot, E.2    Hougaard, P.3    Nerup, J.4
  • 49
    • 0023550313 scopus 로고
    • Age-corrected empirical genetic risk estimates for first-degree relatives of IDDM patients
    • Tillil H, Köbberling J. Age-corrected empirical genetic risk estimates for first-degree relatives of IDDM patients. Diabetes 1987; 36: 93-99.
    • (1987) Diabetes , vol.36 , pp. 93-99
    • Tillil, H.1    Köbberling, J.2
  • 50
  • 52
    • 0027391608 scopus 로고
    • Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD-64) showed 64K autoantibody positivity at onset predicts diabetes type
    • Hagopian WA, Karlsen AE, Gottsäter A, et al. Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD-64) showed 64K autoantibody positivity at onset predicts diabetes type. J Clin Invest 1993; 91: 368-374.
    • (1993) J. Clin. Invest. , vol.91 , pp. 368-374
    • Hagopian, W.A.1    Karlsen, A.E.2    Gottsäter, A.3
  • 53
    • 0033058487 scopus 로고    scopus 로고
    • Molecular Genetics of Maturity-onset Diabetes of the Young
    • Froguel P, Velho G. Molecular Genetics of Maturity-onset Diabetes of the Young. Trends Endocrinol Metabol 1999; 10: 142-146.
    • (1999) Trends Endocrinol. Metabol. , vol.10 , pp. 142-146
    • Froguel, P.1    Velho, G.2
  • 54
    • 0030256832 scopus 로고    scopus 로고
    • Association between HLA and islet cell antibodies in diabetic patients with a mitochondrial DNA mutation at base pair 3243
    • Kobayashi T, Oka Y, Katagiri H, et al. Association between HLA and islet cell antibodies in diabetic patients with a mitochondrial DNA mutation at base pair 3243. Diabetologia 1996; 39: 1196-1200.
    • (1996) Diabetologia , vol.39 , pp. 1196-1200
    • Kobayashi, T.1    Oka, Y.2    Katagiri, H.3
  • 55
    • 0026734966 scopus 로고
    • Maternal-child blood group incompatibiity and other perinatal events increased the risk for early-onset type 1 (insulin-dependent) diabetes melllitus
    • Dahlquist G, Källen B. Maternal-child blood group incompatibiity and other perinatal events increased the risk for early-onset type 1 (insulin-dependent) diabetes melllitus. Diabetologia 1992; 35: 671-675.
    • (1992) Diabetologia , vol.35 , pp. 671-675
    • Dahlquist, G.1    Källen, B.2
  • 56
    • 15444356485 scopus 로고    scopus 로고
    • Predictors of IDDM recurrence risk in offspring of Danish IDDM patients
    • Danish IDDM Epidemiology and Genetics Group
    • Lorenzen T, Pociot F, Stilgren L, et al. Predictors of IDDM recurrence risk in offspring of Danish IDDM patients. Danish IDDM Epidemiology and Genetics Group. Diabetologia 1998; 41: 666-673.
    • (1998) Diabetologia , vol.41 , pp. 666-673
    • Lorenzen, T.1    Pociot, F.2    Stilgren, L.3
  • 57
    • 0035704552 scopus 로고    scopus 로고
    • The thrifty phenotype hypothesis
    • Hales CN, Barker DJ. The thrifty phenotype hypothesis. Br Med Bull 2001; 60: 5-20.
    • (2001) Br. Med. Bull. , vol.60 , pp. 5-20
    • Hales, C.N.1    Barker, D.J.2
  • 58
    • 0029822895 scopus 로고    scopus 로고
    • Intrauterine growth pattern and risk of childhood onset insulin dependent (type I) diabetes: Population based case-control study
    • Dahlquist G, Bennich SS, Kallen B. Intrauterine growth pattern and risk of childhood onset insulin dependent (type I) diabetes: population based case-control study. BMJ 1996; 313: 1174-1177.
    • (1996) BMJ , vol.313 , pp. 1174-1177
    • Dahlquist, G.1    Bennich, S.S.2    Kallen, B.3
  • 59
    • 0035857997 scopus 로고    scopus 로고
    • Birth weight and childhood onset type 1 diabetes: Population based cohort study
    • Stene LC, Magnus P, Lie RT, Sovik O, Joner G. Birth weight and childhood onset type 1 diabetes: population based cohort study. BMJ 2001; 322: 889-892.
    • (2001) BMJ , vol.322 , pp. 889-892
    • Stene, L.C.1    Magnus, P.2    Lie, R.T.3    Sovik, O.4    Joner, G.5
  • 60
    • 0024560219 scopus 로고
    • The Swedish childhood diabetes study-social and perinatal determinants for diabetes in childhood
    • Blom L, Dahlquist G, Nyström L, Sandström A, Wall S. The Swedish childhood diabetes study-social and perinatal determinants for diabetes in childhood. Diabetologia 1989; 32: 7-13.
    • (1989) Diabetologia , vol.32 , pp. 7-13
    • Blom, L.1    Dahlquist, G.2    Nyström, L.3    Sandström, A.4    Wall, S.5
  • 61
    • 0032836936 scopus 로고    scopus 로고
    • Perinatal risk factors for childhood type 1 diabetes in Europe
    • The EURODIAB Substudy 2 Study Group
    • Dahlquist GG, Patterson C, Soltesz G. Perinatal risk factors for childhood type 1 diabetes in Europe. The EURODIAB Substudy 2 Study Group. Diabetes Care 1999; 22: 1698-1702.
    • (1999) Diabetes Care , vol.22 , pp. 1698-1702
    • Dahlquist, G.G.1    Patterson, C.2    Soltesz, G.3
  • 62
    • 0034641540 scopus 로고    scopus 로고
    • Influence of maternal age at delivery and birth order on risk of type 1 diabetes in childhood: Prospective population based family study
    • Bart's-Oxford Family Study Group
    • Bingley PJ, Douek IF, Rogers CA, Gale EA. influence of maternal age at delivery and birth order on risk of type 1 diabetes in childhood: prospective population based family study. Bart's-Oxford Family Study Group. BMJ 2000; 321: 420-424.
    • (2000) BMJ , vol.321 , pp. 420-424
    • Bingley, P.J.1    Douek, I.F.2    Rogers, C.A.3    Gale, E.A.4
  • 63
    • 0031846094 scopus 로고    scopus 로고
    • Pre-natal and early life risk factors for childhood onset diabetes mellitus: A record linkage study
    • Jones M, Swerdlow A, Gill L, Goldacre M. Pre-natal and early life risk factors for childhood onset diabetes mellitus: a record linkage study. Int J Epidemiol 1998; 27: 444-449.
    • (1998) Int. J. Epidemiol. , vol.27 , pp. 444-449
    • Jones, M.1    Swerdlow, A.2    Gill, L.3    Goldacre, M.4
  • 64
  • 65
    • 0043269888 scopus 로고    scopus 로고
    • Environmental risk factors for type 1 diabetes in Rome and province
    • Visalli N, Sebastiani L, Adorisio E, et al. Environmental risk factors for type 1 diabetes in Rome and province. Arch Dis Child 2003; 88: 695-698.
    • (2003) Arch. Dis. Child , vol.88 , pp. 695-698
    • Visalli, N.1    Sebastiani, L.2    Adorisio, E.3
  • 66
    • 0036326325 scopus 로고    scopus 로고
    • Maternal first-trimester enterovirus infection and future risk of type 1 diabetes in the exposed fetus
    • Viskari HR, Roivainen M, Reunanen A, et al. Maternal first-trimester enterovirus infection and future risk of type 1 diabetes in the exposed fetus. Diabetes 2002; 51: 2568-2571.
    • (2002) Diabetes , vol.51 , pp. 2568-2571
    • Viskari, H.R.1    Roivainen, M.2    Reunanen, A.3
  • 67
    • 0141453947 scopus 로고    scopus 로고
    • Group S: No association between preeclampsia or cesarean section and incidence of type 1 diabetes among children: A large, population-based cohort study
    • Stene LC, Magnus P, Lie RT, Sovik O, Joner G, Diabetes NC. Group. S: No association between preeclampsia or cesarean section and incidence of type 1 diabetes among children: a large, population-based cohort study. Pediatr Res 2003; 54: 487-490.
    • (2003) Pediatr. Res. , vol.54 , pp. 487-490
    • Stene, L.C.1    Magnus, P.2    Lie, R.T.3    Sovik, O.4    Joner, G.5    Diabetes, N.C.6
  • 68
    • 0028032269 scopus 로고
    • Inheritance of MHC class II genes in IDDM studied in population-based affected and control families
    • Kockum I, Wassmuth R, Holmberg E, Michelsen B, Lernmark AA. Inheritance of MHC class II genes in IDDM studied in population-based affected and control families. Diabetologia 1994; 37: 1105-1112.
    • (1994) Diabetologia , vol.37 , pp. 1105-1112
    • Kockum, I.1    Wassmuth, R.2    Holmberg, E.3    Michelsen, B.4    Lernmark, A.A.5
  • 69
  • 72
    • 0026033205 scopus 로고
    • The Swedish childhood diabetes study: Vaccinations and infections as risk determinants for diabetes in childhood
    • Blom L, Nyström L, Dahlquist G. The Swedish childhood diabetes study: Vaccinations and infections as risk determinants for diabetes in childhood. Diabetologia 1991; 34: 176-181.
    • (1991) Diabetologia , vol.34 , pp. 176-181
    • Blom, L.1    Nyström, L.2    Dahlquist, G.3
  • 73
    • 0036834465 scopus 로고    scopus 로고
    • The epidemiology of type 1 diabetes in children in Philadelphia 1990-1994: Evidence of an epidemic
    • Lipman TH, Chang Y, Murphy KM. The epidemiology of type 1 diabetes in children in Philadelphia 1990-1994: evidence of an epidemic. Diabetes Care 2002; 25: 1969-1975.
    • (2002) Diabetes Care , vol.25 , pp. 1969-1975
    • Lipman, T.H.1    Chang, Y.2    Murphy, K.M.3
  • 74
    • 18344406353 scopus 로고    scopus 로고
    • No major association of breast-feeding, vaccinations, and childhood viral diseases with early islet autoimmunity in the German BABYDIAB Study
    • Hummel M, Fuchtenbusch M, Schenker M, Ziegler AG. No major association of breast-feeding, vaccinations, and childhood viral diseases with early islet autoimmunity in the German BABYDIAB Study. Diabetes Care 2000; 23: 969-974.
    • (2000) Diabetes Care , vol.23 , pp. 969-974
    • Hummel, M.1    Fuchtenbusch, M.2    Schenker, M.3    Ziegler, A.G.4
  • 75
    • 18344414945 scopus 로고    scopus 로고
    • Childhood vaccinations, vaccination timing, and risk of type 1 diabetes mellitus
    • DeStefano F, Mullooly JP, Okoro CA, et al. Childhood vaccinations, vaccination timing, and risk of type 1 diabetes mellitus. Pediatrics 2001; 108: E112.
    • (2001) Pediatrics , vol.108
    • DeStefano, F.1    Mullooly, J.P.2    Okoro, C.A.3
  • 76
    • 0026447593 scopus 로고
    • Feeding in infancy and the risk of type 1 diabetes mellitus in Finnish children
    • The 'Childhood Diabetes in Finland' Study Group
    • Virtanen SM, Rasanen L, Aro A, et al. Feeding in infancy and the risk of type 1 diabetes mellitus in Finnish children. The 'Childhood Diabetes in Finland' Study Group. Diabet Med 1992; 9 815-819.
    • (1992) Diabet. Med. , vol.9 , pp. 815-819
    • Virtanen, S.M.1    Rasanen, L.2    Aro, A.3
  • 77
    • 0032925805 scopus 로고    scopus 로고
    • Islet autoandbodies in cord blood from children who developed type I (insulin-dependent) diabetes mellitus before 15 years of age
    • [see comments]
    • Lindberg B, Ivarsson SA, Landin-Olsson M, Sundkvist G, Svanberg L, Lernmark A. Islet autoandbodies in cord blood from children who developed type I (insulin-dependent) diabetes mellitus before 15 years of age [see comments]. Diabetologia 1999; 42: 181-187.
    • (1999) Diabetologia , vol.42 , pp. 181-187
    • Lindberg, B.1    Ivarsson, S.A.2    Landin-Olsson, M.3    Sundkvist, G.4    Svanberg, L.5    Lernmark, A.6
  • 78
    • 0842263979 scopus 로고    scopus 로고
    • Postnatal elimination of transplacentally acquired disease-associated antibodies in infants born to families with type 1 diabetes
    • The Finnish TRIGR Study Group. Trial to Reduce IDDM in the Genetically at Risk
    • Hämälainen AM, Ronkainen MS, Akerblom HK, Knip M. Postnatal elimination of transplacentally acquired disease-associated antibodies in infants born to families with type 1 diabetes. The Finnish TRIGR Study Group. Trial to Reduce IDDM in the Genetically at Risk. J Clin Endocrinol Metab 2000; 85: 4249-4253.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 4249-4253
    • Hämälainen, A.M.1    Ronkainen, M.S.2    Akerblom, H.K.3    Knip, M.4
  • 79
    • 0036268505 scopus 로고    scopus 로고
    • Diabetes-related autoantibodies in cord blood from children of healthy mothers have disappeared by the time the child is one year old
    • Ludvigsson J, Wahlberg J. Diabetes-related autoantibodies in cord blood from children of healthy mothers have disappeared by the time the child is one year old. Ann N Y Acad Sci 2002; 958: 289-292.
    • (2002) Ann. N. Y. Acad. Sci. , vol.958 , pp. 289-292
    • Ludvigsson, J.1    Wahlberg, J.2
  • 80
    • 0842311551 scopus 로고    scopus 로고
    • Is presence of islet autoantibodies at birth associated with development of persistent islet autoimmunity? The Diabetes Autoimmunity Study in the Young (DAISY)
    • Stanley HM, Norris JM, Barriga K, et al. Is presence of islet autoantibodies at birth associated with development of persistent islet autoimmunity? The Diabetes Autoimmunity Study in the Young (DAISY). Diabetes Care 2004; 27: 497-502.
    • (2004) Diabetes Care , vol.27 , pp. 497-502
    • Stanley, H.M.1    Norris, J.M.2    Barriga, K.3
  • 82
    • 0036201211 scopus 로고    scopus 로고
    • Islet autoantibodies in cord blood: Maternal, fetal, or neither?
    • Rewers M. Islet autoantibodies in cord blood: maternal, fetal, or neither?. Diabetes Metab Res Rev 2002; 18: 2-4.
    • (2002) Diabetes Metab. Res. Rev. , vol.18 , pp. 2-4
    • Rewers, M.1
  • 83
    • 0036706710 scopus 로고    scopus 로고
    • Autoimmunity and familial risk of type 1 diabetes
    • Hämälainen AM, Knip M. Autoimmunity and familial risk of type 1 diabetes. Curr Diabet Rep 2002; 2: 347-353.
    • (2002) Curr. Diabet. Rep. , vol.2 , pp. 347-353
    • Hämälainen, A.M.1    Knip, M.2
  • 84
    • 0347990607 scopus 로고    scopus 로고
    • Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes
    • Koczwara K, Bonifacio E, Ziegler AG. Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes. Diabetes 2004; 53: 1-4.
    • (2004) Diabetes , vol.53 , pp. 1-4
    • Koczwara, K.1    Bonifacio, E.2    Ziegler, A.G.3
  • 85
    • 0024373402 scopus 로고
    • Islet cell and other organ-specific autoantibodies in all children developing type 1 (insulin-dependent) diabetes mellitus in Sweden during one year and in matched controls
    • Landin-Olsson M, Karlsson A, Dahlquist G, Blom L, Lernmark AA, Sundkvist G. Islet cell and other organ-specific autoantibodies in all children developing type 1 (insulin-dependent) diabetes mellitus in Sweden during one year and in matched controls. Diabetologia 1989; 32: 387-395.
    • (1989) Diabetologia , vol.32 , pp. 387-395
    • Landin-Olsson, M.1    Karlsson, A.2    Dahlquist, G.3    Blom, L.4    Lernmark, A.A.5    Sundkvist, G.6
  • 88
    • 0033080953 scopus 로고    scopus 로고
    • Comparison of tissue transglutaminase-specific antibody assays with established antibody measurements for coeliac disease
    • Bazzigaluppi E, Lampasona V, Barera G, et al. Comparison of tissue transglutaminase-specific antibody assays with established antibody measurements for coeliac disease. J Autoimmun 1999; 12:51-56.
    • (1999) J. Autoimmun. , vol.12 , pp. 51-56
    • Bazzigaluppi, E.1    Lampasona, V.2    Barera, G.3
  • 89
    • 0141816761 scopus 로고    scopus 로고
    • Timing of initial cereal exposure in infancy and risk of islet autoimmunity
    • Norris JM, Barriga K, Klingensmith G, et al. Timing of initial cereal exposure in infancy and risk of islet autoimmunity. JAMA 2003;290:1713-1720.
    • (2003) JAMA , vol.290 , pp. 1713-1720
    • Norris, J.M.1    Barriga, K.2    Klingensmith, G.3
  • 90
    • 0025289265 scopus 로고
    • S.G.I.W: Dietary factors and the risk of developing insulin dependent diabetes in childhood
    • Dahlquist GG, Blom LG, Persson L-AA, Sandström AIM. S.G.I. W: Dietary factors and the risk of developing insulin dependent diabetes in childhood. BMJ 1990; 300: 1302-1306.
    • (1990) BMJ , vol.300 , pp. 1302-1306
    • Dahlquist, G.G.1    Blom, L.G.2    Persson, L.-A.A.3    Sandström, A.I.M.4
  • 92
    • 0033032385 scopus 로고    scopus 로고
    • Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes
    • Vaarala O, Knip M, Paronen J, et al. Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes. Diabetes 1999; 48: 1389-1394.
    • (1999) Diabetes , vol.48 , pp. 1389-1394
    • Vaarala, O.1    Knip, M.2    Paronen, J.3
  • 93
    • 11144312195 scopus 로고
    • Psychological stress and the onset of IDDM in children
    • Thernlund GM, Dahlquist G, Hansson K, et al. Psychological stress and the onset of IDDM in children. 1995; 18.
    • (1995) , pp. 18
    • Thernlund, G.M.1    Dahlquist, G.2    Hansson, K.3
  • 94
    • 0026611349 scopus 로고
    • Growth velocity and development of insulin-dependent diabetes mellitus
    • Blom L, Persson LA, Dahlquist G. Growth velocity and development of insulin-dependent diabetes mellitus Diabetologia 1992; 35: 528-533.
    • (1992) Diabetologia , vol.35 , pp. 528-533
    • Blom, L.1    Persson, L.A.2    Dahlquist, G.3
  • 95
    • 0032939358 scopus 로고    scopus 로고
    • Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabetes mellitus
    • EURODIAB. The EURODIAB Substudy 2 Study Group
    • EURODIAB. Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabetes mellitus. The EURODIAB Substudy 2 Study Group. Diabetologia 1999; 42: 51-54.
    • (1999) Diabetologia , vol.42 , pp. 51-54
  • 96
    • 0037648405 scopus 로고    scopus 로고
    • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
    • Ueda H, Howson JM, Esposito L, et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003; 423: 506-511.
    • (2003) Nature , vol.423 , pp. 506-511
    • Ueda, H.1    Howson, J.M.2    Esposito, L.3
  • 97
    • 0036897063 scopus 로고    scopus 로고
    • The rise of childhood type 1 diabetes in the 20th century
    • Gale EA. The rise of childhood type 1 diabetes in the 20th century. Diabetes 2002; 51: 3353-3361.
    • (2002) Diabetes , vol.51 , pp. 3353-3361
    • Gale, E.A.1


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