Optimized autoantibody-based risk assessment in family members: Implications for future intervention trials

Diabetes Care

Volumn 22, Issue 11, 1999, Pages 1796-1801

  Bingley, Polly J ^a   Williams, Alistair J K ^b   Gale, Edwin A M ^b  

^a SOUTHMEAD HOSPITAL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; PANCREAS ISLET CELL ANTIBODY;

ADULT; ARTICLE; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; DISEASE MARKER; FEMALE; HUMAN; IMMUNOASSAY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; RISK ASSESSMENT; SCREENING TEST;

ADOLESCENT; ADULT; AUTOANTIBODIES; CLINICAL TRIALS; DIABETES MELLITUS, TYPE 1; FAMILY HEALTH; FEMALE; FORECASTING; GLUTAMATE DECARBOXYLASE; HUMANS; INSULIN; ISLETS OF LANGERHANS; LIFE TABLES; MALE; POPULATION SURVEILLANCE; RISK ASSESSMENT;

EID: 0032710530     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.22.11.1796     Document Type: Article

References (18)

1. Gale EAM: Theory and practice of nicotin-amide trials in pre-type 1 diabetes. J Pediatr Endocrinol Metab 9:375-379, 1996
2. Skyler JS, Marks JB: Immune intervention in type 1 diabetes mellitus. Diabetes Rev 1: 15-42, 1993
3. Bonifacio E, Genovese S, Braghi S, Bazzigaluppi E, Lampasona V, Bingley PJ, Rogge L, Pastore MR, Bognetti E, Bottazzo GF, Gale EAM: Islet autoantibody markers in IDDM: risk assessment strategies yielding high sensitivity. Diabetologa 38:816-822, 1995
4. Seissler J, Morgenthaler NG, Achenbach P, Lampeter EF, Glawe D, Payton MA, Christie MR, Scherbaum WA, for the DENIS Study Group: Combined screening for autoantibodies to IA-2 and antibodies to glutamic acid decarboxylase in first degree relatives of patients with IDDM. Diabetologia 39: 1351-1356, 1996
5. Dittler J, Seidel D, Schenker M, Ziegler AG: GADIA2-combi determination as first-line screening for improved prediction of type 1 diabetes in relatives. Diabetes 47:592-597, 1998
6. Myers MA, Rabin DU, Rowley MJ: Pancreatic islet cell cytoplasmic antibody in diabetes is represented by antibodies to islet cell antigen 512 and glutamic acid decarboxylase. Diabetes 44:1290-1295, 1995
7. Petersen JS, Hejnaes KR, Moody A, Karlsen AE, Marshall MO, Hoier-Madsen M, Boel E, Michelsen BK, Dyrberg T: Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radio-ligand assay. Diabetes 43:459-467, 1994
8. Bonifacio E, Lampasona V, Genovese S, Ferrari M, Bosi E: Identification of protein tyrosine phosphatase-like 1A2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies. J Immunol 155:5419-5426, 1995
9. Hawkes CJ, Wasmeier C, Christie MR, Hutton JC: Identification of the 37-kDa antigen in IDDM as a tyrosine phosphatase-like protein (Phogrin) related to 1A-2. Diabetes 45:1187-1192, 1996
10. Williams AJK, Bingley PJ, Bonifacio E, Palmer JP, Gale EAM: A novel micro-assay for insulin autoantibodies. J Autoimmun 10:473-478, 1997
11. Vardi P, Ziegler AG, Mathews JH, Dib S, Keller RJ, Ricker AT, Wolfsdorf JI, Herskowitz RD, Rabizadeh A, Eisenbarth GS, Soeldner JS: Concentration of insulin autoantibodies at onset of type 1 diabetes: inverse log-linear correlation with age. Diabetes Care 11:736-739, 1988
12. Bingley PJ, Bonifacio E, Williams AJK, Genovese S, Bottazzo GF, Gale EAM: Prediction of IDDM in the general population: strategies based on combinations of autoantibody markers. Diabetes 46:1701-1710, 1997
13. Vandewalle CL, Coeckelberghs MI, De Leeuw IH, Du Caju MV, Schuit FC, Pipeleers DG, Gorus FK, for the Belgian Diabetes Registry: Epidemiology, clinical aspects, and biology of IDDM patients under age 40 years. Diabetes Care 20:1556-1561, 1997
14. Bingley PJ, Gale EAM: The incidence of insulin-dependent diabetes in England: a study in the Oxford region 1985-6. Br Med J 298:558-560, 1989
15. Bingley PJ, Bonifacio E, Shattock M, Gillmor HA, Sawtell PA, Dunger DB, Scott RDM, Bottazzo GF, Gale EAM: Can islet cell antibodies predict IDDM in the general population? Diabetes Care 16:45-50, 1993
16. Verge CF, Stenger D, Bonifacio E, Colman PG, Pilcher C, Bingley PJ, Eisenbarth GS, participating laboratories: Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop. Diabetes 47:1857-1866, 1998
17. Bland JM: An Introduction to Medical Statistics. Oxford, U.K., Oxford University Press, 1995
18. World Health Organization: Diabetes Mellitus: Report of a WHO Study Group. Geneva, World Health Org., 1985 (Tech. Rep. Ser., no. 727)