Advances in the analysis of mycotoxins and its quality assurance

Food Additives and Contaminants

Volumn 22, Issue 4, 2005, Pages 345-353

  Krska, Rudolf ^a   Welzig, Elvira ^a   Berthiller, F ^a   Molinelli, A ^b   Mizaikoff, B ^b  

^a INSTITUTE FOR MICROELECTRONICS   (Austria)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Analysis; Clean up; Detection; Mycotoxins; Quality assurance

Indexed keywords

AFLATOXIN; MYCOTOXIN; OCHRATOXIN; POLYMER; TRICHOTHECENE; VOMITOXIN; ZEARALENONE;

ARTICLE; BIOSENSOR; COLUMN CHROMATOGRAPHY; CONCENTRATION RESPONSE; FOOD CONTAMINATION; FOOD QUALITY; FUNGAL CONTAMINATION; IMMUNOAFFINITY CHROMATOGRAPHY; INFRARED SPECTROSCOPY; LABORATORY TEST; LIQUID CHROMATOGRAPHY; MACROMOLECULE; MAIZE; MASS SPECTROMETRY; MOLECULAR IMPRINTING; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUALITY CONTROL; SCREENING; TOXICITY TESTING; WHEAT;

FOOD ANALYSIS; FOOD CONTAMINATION; MYCOTOXINS; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

TRITICUM AESTIVUM; ZEA MAYS;

EID: 19544364109     PISSN: 0265203X     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652030500070192     Document Type: Article

References (62)

1. Åberg L, Andren H, Persson J-Å, Pettersson H. 2002. Rapid analysis of mycotoxins in grain with NIT. ICC Conference Budapest. May 2002.
2. AOAC 2002. In: Horwitz W, editor. Official methods of analysis of the association of official analytical chemists 17th ed. Current through revision Arlington, USA: Method Nr. 986;18.
3. Balzer I, Bogdanic C, Pepejnjak S. 1978. Rapid thin layer chromatographic method for determining aflatoxin B1, ochratoxin A, and zearalenone in corn. Journal of the Association of Official Analytical Chemists 61:584-585.
4. Barna-Vetró I, Gyöngyösi À, Solti, L. 1997. Immunodiagnostics for mycotoxin determination. Hungarian Agricultural Research 2:16-19.
5. Berger U, Oehme M, Kuhn F. 1999. Quantitative determination and structural elucidation of type A- and B-trichothecenes by HPLC/ion trap multiple mass spectrometry. Journal of Agricultural and Food Chemistry 47:4240-4245.
6. Buttinger G, Knapp H, Fuchs E, Binder EM, Krska R. 2003. New rapid clean-up device for Ochratoxin A. Proceedings of the International Symposium of Mycotoxins (Kagawa, Japan, 3-5 November 2003).
7. Coker R. 2000. Aflatoxins and mycotoxins: Chromatography. In: Wilson ID, Adlard TR, Cooke M, CF, editors. Encyclopedia of separation science. Poole Academic Press. pp 1873-1888.
8. Cole R, Cox R. 1981. Handbook of Toxic Fungal Metabolites, New York, Academic Press.
9. Driffield M, Hird SJ, MacDonald J. 2003. The occurrence of a range of mycotoxins in animal offal food products by HPLC-MS/MS. Aspects of Applied Biology 68:205-210.
10. EN 12955, 1999. Foodstuffs. Determination of aflatoxin B1, and the sum of aflatoxins B1, B2, G1 and G2 in cereals, shell-fruits and derived products; High performance liquid chromatographic method with post column derivatization and immunoaffinity column clean-up.
11. EN 13585, 2001. Foodstuffs. Determination of fumonisins B1 and B2 in maize; HPLC method with solid phase extraction clean-up.
12. EN 14123, 2003. Foodstuffs. Determination of aflatoxin B1 and the sum of aflatoxin B1, B2, G1 and G2 in peanuts, pistachios, figs, and paprika powder; High performance liquid chromatographic method with postcolumn derivatization and immunoaffinity column clean-up.
13. EN 14132, 2003. Foodstuffs. Determination of ochratoxin A in barley and roasted coffee; HPLC method with immunoaffinity column clean-up.
14. EN 14177, 2003. Foodstuffs. Determination of patulin in clear and cloudy apple juice and puree; HPLC method with liquid/liquid partition clean-up.
15. EN 14352, 2004. Foodstuffs. Determination of fumonisin B1 and B2 in maize based foods; HPLC method with immunoaffinity column clean-up.
16. European Commission. 1998. Commission Directive 98/53/EC of 16 July 1998 laying down the sampling methods and the methods of analysis for the official control of the levels of certain contaminants in foodstuffs. Official Journal of the European Communities L201:93-101.
17. Freudenschuss M. 2003. www.biopure.at
18. Frisvad JC, Thrane U. 1987. Standardized high-performance liquid chromatography of 182 mycotoxins and other fungal metabolites based on alkylphenone retention indices and UV-VIS spectra (diodearray detection). Journal of Chromatography 404:195-214.
19. Fuchs E, Binder EM, Heidler D, Krska R. 2002. Structural characterisation of metabolites after the microbial degradation of A-trichothecenes by the bacterial strain BBSH 797. Food Additives and Contaminants 19:379-386.
20. Gilbert J, Anklam E. 2002. Validation of analytical methods for determining mycotoxins in foodstuffs. Trends in Analytical Chemistry 21:468-486.
21. JECFA 2001. Joint FAO/WHO Expert Commitee on Food Additives, 56th Meeting, Geneva, 6-15 February 2001.
22. Jodlbauer J, Maier N, Lindner W. 2002. Towards ochratoxin. A selective molecularly imprinted polymers for solid-phase extraction. Journal of Chromatography A 945:45-63.
23. Johann H, Dose K. 1983. Multianalytical method for the routine determination of the aflatoxins B1, B2, G1 and G2, and of citrinin, ochratoxin A, patulin, penicillic acid and sterigmatocystin in molded foods. Fresenius Zeitschrift der Analytischen Chemie 314:139-142.
24. Josephs RD, Krska R, MacDonald S, Wilson P, Pettersson H. 2003. Preparation of a calibrant to be used as a certified reference material for the determination of the Fusarium mycotoxin zearalenone. Journal of AOAC International 86:50-60.
25. Josephs RD, Schuhmacher R, Krska R. 2001. International interlaboratory study for the determination of the Fusarium mycotoxins zearalenone and deoxynivalenol in agricultural commodities. Food Additives and Contaminants 18: 417-430.
26. Kandler W, Nadubinská M, Parich A, Krska R. 2002. Determination of moniliformin in maize by ion chromatography. Analytical and Bioanalytical Chemistry 374:1086-1090.
27. Kos G, Lohninger H, Krska R. 2003. Development of a method for the determination of Fusarium fungi on corn using mid-Infrared spectroscopy with attenuated total reflection and chemometrics. Analytical Chemistry 75:1211-1217.
28. Krska R, Baumgartner S, Josephs R. 2001. The state-of-the-art in the analysis of type-A and -B trichothecende mycotoxins in cereals. Fresenius' Journal of Analytical Chemistry 371: 285-299.
29. Krska R, Welzig E, Josephs RD, Kandler W, Pettersson H, MacDonald S, Charlton A, Brereton P, Hametner C, Berner D, Zöllner P. 2003. Purity assessment of crystalline zearalenone, Journal of AOAC International 86:722-728.
30. Lew H, Chelkowski J, Wakulinski W, Edinger W. 1993. Moniliformin in wheat and triticale grain. Mycotoxin Research 9:66-71.
31. Luo Y, Liu F, Zheng J, Yang J. 1992. Systematic extraction, separation, and detection of Fusarium mycotoxins in cereals. Junshi Yixue Kexueyuan Yuankan 16:20-25.
32. Maragos CM. 2002. Novel assays and sensor platforms for the detection of aflatoxins. Advances in Experimental Medicine and Biology 504:85-93.
33. Märtlbauer E, Dietrich R, Terplan G. 1991. Erfahrungen bei der Anwendung von Immunoassays zum Nachweis von Mykotoxinen in Lebensmitteln. Archiv für Lebensmittelhygiene 42:3-6.
34. Molinelli A, Weiss R, Mizaikoff B. 2002. Advanced solid phase extraction using molecularly imprinted polymers for the determination of flavonoids in red wine. Journal of Agricultural and Food Chemistry 50:1804-1808.
35. Nadubinská M, Parich A, Krska R, Kandler W, Sraboarová A, Eged S. 2002. Contents of zearalenone, deoxynivalenol, moniliformin and fusaric acid in maize ears from Slovakia naturally contaminated with Fusarium spp. Journal of Applied Genetics 43A:133-140.
36. Parich A, Schuch Boeira L, Perez Castro S, Krska R. 2004. Determination of moniliformin using SAX column clean-up and HPLC/DAD-detection. Mycotoxin Research (accepted).
37. Pettersson H, Aberg L. 2002. Rapid estimation of deoxynivalenol and Fusarium by near infared spectrocopy. Journal of Applied Genetics 43A:141-144.
38. Pettersson H, Langseth W. 2002a. Intercomparison of trichothecene analysis and feasibility to produce certified calibrants and reference material. Final report I, Method Studies. BCR Information, Project Report EUR 20285/1 EN 1-82.
39. Pettersson H, Langseth W. 2002b. Intercomparison of trichothecene analysis and feasibility to produce certified calibrants and reference material. Final report I, Homogeneity and Stability Studies, Final Intercomparison. BCRInformation, EU Project Report EUR 20285/2 EN 1-145.
40. Razzazi-Fazeli E, Böhm J, Luf W. 1999. Determination of nivalenol and deoxynivalenol in wheat using liquid chromatography-mass spectrometry with negative ion atmospheric pressure chemical ionisation. Journal of Chromatography A 854:45-55.
41. Rottinghaus GE, Olesen B, Osweiler GD. 1982. Rapid screening method for aflatoxin B1, zearalenone, ochratoxin A, T-2 toxin, diacetoxyscirpenol and vomitoxin. Proceedings of the annual meeting - American Association of Veterinarian Laboratory Diagnostics. Coume Date 1982, 25th, 477-482.
42. Rundberget T, Wilkins AL. 2002. Determination of penicillium mycotoxins in foods and feeds using liquid chromatography-mass spectrometry. Journal of Chromatography A 964: 189-197.
43. Schneider E, Usleber E, Märtlbauer E, Terplan G. 1995. Multimycotoxin dipstick enzyme immunoassay applied to wheat. Food Additives and Contaminants 12:387-393.
44. Schnerr H, Vogel RF, Niessen L. 2002. A biosensor-based immunoassay for rapid screening of deoxynivalenol contamination in wheat. Food and Agricultural Immunology 14:313-321.
45. Schuhmacher R, Krska R, Grasserbauer M. 1997. Interlaboratory comparison test for the determination of the Fusarium mycotoxins deoxynivalenol in wheat and zearalenone in maize. Fresenius' Journal of Analytical Chemistry 359:510-515.
46. Schuller PL, Horwitz W, Stoloff L. 1976. A review of sampling plans and collaboratively studied methods of analysis for aflatoxins. Journal of the Association of Official Analytical Chemists 59:1315-1343.
47. Scott PM, Kanhere SR, Tarter EJ. 1986. Determination of nivalenol and deoxynivalenol in cereals by electron-capture gas chromatography. Journal of the Association of Official Analytical Chemists 69:889-893.
48. Scott PM, Lawrence BA. 1987, Liquid chromatographic determination and stability of the Fusarium mycotoxin monilifomin in cereal grains. Journal of AOAC 70:850-853.
49. Sharman M, Gilbert J, Chelkowski J. 1991. A survey of the co-occurrence of the mycotoxin moniliformin in cereal samples from sources worldwide. Food Additives and Contaminants 8:459-466.
50. Shephard G. 1998. Chromatographic determination of the fumonisin mycotoxins, Journal of Chromatography A 815: 31-39.
51. Tanaka T, Yoneda A, Inoue S, Sugiura Y, Ueno Y. 2000. Simultaneous determination of trichothecene mycotoxins and zearalenone in cereals by gas chromatography-mass spectrometry. Journal of Chromatography A 882:23-28.
52. Thiel PG, Meyer CJ, Marasas WFO. 1982. Natural Occurrence of Moniliformin together with deoxynivalenol and zearalenone in transkeian Corn. Journal of Agricultural and Food Chemistry 30:308-312.
53. Thiel PG. 1990. Determination of moniliformin by high-performance liquid chromatography. Journal of Environmental Pathology, Toxicology and Oncology 10:162-165.
54. Trucksess M, Page S, Wood G, Cho T. 1998. Determination of dexoynivalenol in white flour, whole wheat flour, and bran by solid phase extraction/liquid chromatography: Interlaboratory study. Journal of AOAC International 81:880-886.
55. Tudos AJ, Lucas-van den Bos ER, Stigter EC. 2003. Rapid surface plasmon resonance-based inhibition assay of deoxynivalenol. Journal of Agricultural and Food Chemistry 51:5843-5848.
56. Uhlig S, Torp M, Gutleb A, Krska R. 2003. The ability of Fusarium avenaceum to accumulate moniliformin in Norwegian grain. The World Mycotoxin Forum, Noordwijk aan Zee, The Netherlands, 17-18 February.
57. Visconti A, Boenke A, Doko MB, Solfrizzo M, Pascale M. 1995. Occurrence of fumonisins in Europe and the BCR-measurement and testing projects. Natural Toxins 3:269-274, discussion 280.
58. Visconti A, Boenke A, Solfrizzo M, Pascale M, Doko MB. 1996. European intercomparison study for the determination of the fumonisin content in two maize materials. Food Additives and Contaminants 13:909-927.
59. Visconti A, Solfrizzo M, De Girolamo A, Boenke A. 2001. Determination of fumonisins at levels of interest for future EU legislation: Development of an analytical method and inter-laboratory validation for maize flour and cornflakes. European Commission, BCR information, Report EUR 10451.
60. Weingärtner J, Krska R, Praznik W, Grasserbauer M. 1997. Use of Mycosep multifunctional clean-up columns for the determination of trichothecenes in wheat by electrone capture gas-chromatography. Fresenius' Journal of Analytical Chemistry 357:1206-1210.
61. Weiss R, Molinelli A, Jakusch M, Mizaikoff B. 2002. Imprinting of Flavonoid compounds and application for solid phase extraction (SPE). Bioseparations 10:379-387.
62. Weiss R, Freudenschuss M, Krska R, Mizaikoff B. 2003. Improving the analysis of mycotoxins in beverages. Molecularly imprinted polymers for deoxynivalenol and zearalenone. Food Additives and Contaminants 20: 386-395.