Quantitative determination and structure elucidation of type A- and B- trichothecenes by HPLC/ion trap multiple mass spectrometry

Journal of Agricultural and Food Chemistry

Volumn 47, Issue 10, 1999, Pages 4240-4245

  Berger, Urs ^a   Oehme, Michael ^a   Kuhn, Fabian ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Fusarium cultures; HPLC multiple MS; Quantification; Structure elucidation; Type A and B trichothecenes

Indexed keywords

MYCOTOXIN; PLANT EXTRACT; TRICHOTHECENE; TRICHOTHECENE DERIVATIVE;

ANIMAL; ANIMAL FOOD; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; EXTRACTION; FOOD CONTROL; FUNGUS CULTURE; FUSARIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERMETHOD COMPARISON; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METHODOLOGY; MICROBIOLOGY; NONHUMAN; STANDARD; STRUCTURE ANALYSIS; WHEAT;

ANIMAL FEED; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOOD MICROBIOLOGY; FUSARIUM; HUMANS; MASS SPECTROMETRY; PLANT EXTRACTS; TRICHOTHECENES; TRITICUM;

ANIMALIA; FUNGI; FUSARIUM; TRITICUM AESTIVUM;

EID: 0033213614     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf9904012     Document Type: Article

References (25)

1. Croteau, S. M.; Prelusky, D. B.; Trenholm, H. L. Analysis of Trichothecene Mycotoxins by Gas Chromatography with Electron Capture Detection. J. Agric. Food Chem. 1994, 42, 928-933.
2. De Nijs, M.; Rombouts, F.; Notermans, S. Fusarium Molds and their Mycotoxins. J. Food Saf. 1996, 16, 15-58.
3. Gilbert, J. Recent Advances in Analytical Methods for Mycotoxins. Food Addit. Contam. 1993, 10, 37-48.
4. Grove, J. F. Macrocyclic Trichothecenes. Nat. Prod. Rep. 1993, 10, 429-448.
5. Jimenez, M.; Mateo, R. Determination of Mycotoxins Produced by Fusarium Isolates from Banana Fruits by Capillary Gas Chromatography and High-Performance Liquid Chromatography. J. Chromatogr. A 1997, 778, 363-372.
6. Kostiainen, R. The Characterization and Analysis of Trichothecenes by Chemical Ionization and Tandem Mass Spectrometry. Thesis, University of Helsinki, 1989.
7. Kostiainen, R. Identification of Trichothecenes by Thermospray, Plasmaspray and Dynamic Fast-Atom Bombardment Liquid Chromatography - Mass Spectrometry. J. Chromatogr. 1991, 562, 555-562.
8. Langseth, W.; Rundberget, T. Instrumental Methods for Determination of Nonmacrocyclic Trichothecenes in Cereals, Foodstuffs and Cultures. J. Chromatogr. A 1998, 815, 103-121.
9. Langseth, W.; Bernhoft, A.; Rundberget, T.; Kosiak, B.; Gareis, M. Mycotoxin Production and Cytotoxicity of Fusarium Strains Isolated from Norwegian Cereals. Mycopathologia 1999, 144, 103-113.
10. Lauren, D. R.; Greenhalgh, R. Simultaneous Analysis of Nivalenol and Deoxynivalenol in Cereals by Liquid Chromatography. J. Assoc. Off. Anal. Chem. 1987, 70, 479-483.
11. Lin, L.; Zhang, J.; Wang, P.; Wang, Y.; Chen, J. Thin-Layer Chromatography of Mycotoxins and Comparison with other Chromatographic Methods. J. Chromatogr. A 1998, 815, 3-20.
12. Müller, H.-M.; Reimann, J.; Schumacher, U.; Schwadorf, K. Fusarium Toxins in Wheat Harvested During Six Years in an Area of Southwest Germany. Nat. Toxins 1997, 5, 24-30.
13. Park, J. J.; Chu, F. S. Assessment of Immunochemical Methods for the Analysis of Trichothecene Mycotoxins in Naturally Occurring Moldy Corn. J. Assoc. Off. Anal. Chem. Int. 1996, 79, 465-471.
14. Patel, S.; Hazel, C. M.; Winterton, A. G. M.; Mortby, E. Survey of Ethnic Foods for Mycotoxins. Food Addit. Contam. 1996, 13, 833-841.
15. Pettersson, H. Intercomparison of Trichothecene Analysis and Feasibility to Produce Certified Calibrants and Reference Material. Directorate-General, Science, Research and Development: Brussels, 1998; EUR 18214 EN; ISBN 92-828-3224-4.
16. Prelusky, D. B.; Rotter, B. A.; Rotter, R. G. Toxicology of Mycotoxins. In Mycotoxins in Grain, Compounds other than Aflatoxins; Miller, J. D., Trenholm, H. L., Eds.; Eagan Press: St. Paul, MN, 1994; pp 359-403.
17. Rajakylä, E.; Laasasenaho, K.; Sakkers, P. J. D. Determination of Mycotoxins in Grain by High-Performance Liquid Chromatography and Thermospray Liquid Chromatography -Mass Spectrometry. J. Chromatogr. 1987, 384, 391-402.
18. Schollenberger, M.; Lauber, U.; Terry Jara, H.; Suchy, S.; Drochner, W.; Müller, H.-M. Determination of Eight Trichothecenes by Gas Chromatography - Mass Spectrometry after Sample Cleanup by a Two-Stage Solid-Phase Extraction. J. Chromatogr. A 1998, 815, 123-132.
19. Schwadorf, K.; Müller, H.-M. Determination of Trichothecenes in Cereals by Gas Chromatography with Ion Trap Detection. Chromatographia 1991, 32, 137-142.
20. Scott, P. M. Mycotoxin Methodology. Food Addit. Contam. 1996, 12, 395-403.
21. Stratton, G. W.; Robinson, A. R.; Smith, H. C.; Kittilsen, L.; Barbour, M. Levels of Five Mycotoxins in Grains Harvested in Atlantic Canada as Measured by High Performance Liquid Chromatography. Arch. Environ. Contam. Toxicol. 1993, 24, 399-409.
22. Weingaertner, J.; Krska, R.; Praznik, W.; Grasserbauer, M.; Lew, H. Use of MysoSep Multifunctional Clean-up Columns for the Determination of Trichothecenes in Wheat by Electron-Capture Gas Chromatography. Fresenius J. Anal. Chem. 1997, 357, 1206-1210.
23. Yoshizawa, T.; Jin, Y.-Z. Natural Occurrence of Acetylated Derivatives of Deoxynivalenol and Nivalenol in Wheat and Barley in Japan. Food Addit. Contam. 1995, 12, 689-694.
24. Young, J. C.; Games, D. E. Supercritical Fluid Chromatography of Fusarium Mycotoxins. J. Chromatogr. 1992, 627, 247-254.
25. Young, J. C.; Games, D. E. Analysis of Fusarium Mycotoxins by Supercritical Fluid Chromatography with Ultraviolet or Mass Spectrometric Detection. J. Chromatogr. A 1993, 653, 374-379.