Neonatal lupus: Basic research and clinical perspectives

Rheumatic Disease Clinics of North America

Volumn 31, Issue 2, 2005, Pages 299-313

  Buyon, Jill P ^a,b   Clancy, Robert M ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NYU HOSPITAL FOR JOINT DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; DEXAMETHASONE; LA ANTIBODY; MATERNAL ANTIBODY; RO ANTIBODY; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

AUTOIMMUNE DISEASE; BREAST FEEDING; CONGENITAL HEART BLOCK; DISEASE CLASSIFICATION; DISEASE COURSE; ELECTROCARDIOGRAM; ERYTHEMA; FIBROSIS; GENETIC ANALYSIS; HUMAN; IMMUNOHISTOLOGY; IN VITRO STUDY; MEDICAL RESEARCH; NEWBORN DISEASE; NEWBORN LUPUS ERYTHEMATOSUS; OPSONIZATION; PREGNANCY; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SJOEGREN SYNDROME; SKIN LUPUS ERYTHEMATOSUS; SYSTEMIC LUPUS ERYTHEMATOSUS;

FEMALE; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; LUPUS ERYTHEMATOSUS, SYSTEMIC; PREGNANCY; PREGNANCY COMPLICATIONS; RISK FACTORS;

EID: 19544363226     PISSN: 0889857X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rdc.2005.01.010     Document Type: Review

References (49)

1. J.P. Buyon Neonatal lupus syndrome R.G. Lahita Systemic lupus erythematosus 4th edition 2004 Elsevier Academic Press San Diego (CA) 449 450
2. L.A. Lee Neonatal lupus erythematosus J Invest Dermatol 100 1993 9s 13s
3. 1RNP-positive antibodies in fraternal twins - is this a subset of neonatal lupus erythematosus or a new distinct syndrome? J Am Acad Dermatol 32 1995 858 862
4. R.M. Laxer, E.A. Roberts, and K.R. Gross Liver disease in neonatal lupus erythematosus J Pediatr 116 1990 238 242
5. R. Watson, J.E. Kang, and M. May Thrombocytopenia in the neonatal lupus syndrome Arch Dermatol 124 1988 560 563
6. L.A. Lee, R.J. Sokol, and J.P. Buyon Hepatobiliary disease in neonatal lupus erythematosus: prevalence and clinical characteristics in cases enrolled in a national registry Pediatrics 109 2002 e11
7. S. Kanagasegar, R. Cimaz, and B.T. Kurien Neonatal lupus manifests as isolated neutropenia and mildly abnormal liver functions J Rheumatol 29 2002 187 191
8. C.M. Story, J.E. Mikulska, and N.E. Simister A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to the fetus J Exp Med 180 1994 2377 2381
9. J.P. Buyon, R. Hiebert, and J. Copel Autoimmune-associated congenital heart block: Mortality, morbidity, and recurrence rates obtained from a national neonatal lupus registry J Am Coll Cardiol 31 1998 1658 1666
10. A. Brucato, M. Frassi, and F. Franceschini Risk of congenital heart block in newborns of mothers with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis Arthritis Rheum 44 2001 1832 1835
11. D.G. Solomon, A. Rupel, and J.P. Buyon Birth order and recurrence rate in autoantibody-associated congenital heart block: implications for pathogenesis and family counseling Lupus 12 2003 646 647
12. G. Gladman, E.D. Silverman, and Yuk-Law Fetal echocardiographic screening of pregnancies of mothers with anti-Ro and/or anti-La antibodies Am J Perinatol 19 2002 73 80
13. H.B. Tran, M. Ohlsson, and D. Beroukas Subcellular redistribution of La(SS-B) autoantigen during physiologic apoptosis in the fetal mouse heart and conduction system: a clue to the pathogenesis of congenital heart block Arthritis Rheum 46 2002 202 208
14. H.B. Tran, P.J. Macardle, and J. Hiscock Anti-La (SS-B) antibodies transported across the placenta bind apoptotic cells in fetal organs targeted in neonatal lupus Arthritis Rheum 46 2002 1572 1579
15. R.M. Clancy, A.D. Askanase, and R.P. Kapur Transdifferentiation of cardiac fibroblasts, a fetal factor in anti-SSA/Ro-SSB/La antibody-mediated congenital heart block J Immunol 169 2002 2156 2163
16. M.E. Miranda, C.E. Tseng, and W. Rashbaum Accessibility of SSA/Ro and SSB/La antigens to maternal autoantibodies in apoptotic human fetal cardiac myocytes J Immunol 161 1998 5061 5069
17. M.E. Miranda-Carus, A.D. Askanase, and R.M. Clancy Anti-SSA/Ro and -SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of tumor necrosis factor alpha by macrophages J Immunol 165 2000 5345 5351
18. R.M. Clancy, and J.P. Buyon Clearance of apoptotic cells: TGF-beta in the balance between inflammation and fibrosis J Leukoc Biol 74 2003 959 960
19. V.A. Fadok, D.A. Bratton, and A. Konowal Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2 and PAF J Clin Invest 101 1998 890 898
20. J.R. Brown, D. Goldblatt, and J. Buddle Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD) J Leukoc Biol 73 2003 591 599
21. A.A. Manfredi, P. Rovere, and G. Galati Apoptotic cell clearance in systemic lupus erythematosus. I. Opsonization by antiphospholipid antibodies Arthritis Rheum 41 1998 205 214
22. R.M. Clancy, R.P. Kapur, and Y. Molad Immunohistologic evidence supports apoptosis, IgG deposition and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block Arthritis Rheum 50 2004 173 182
23. M.R. Awad, A. El-Gamel, and P. Hasleton Genotypic variation in the transforming growth factor-beta1 gene: association with transforming growth factor-beta1 production, fibrotic lung disease, and graft fibrosis after lung transplantation Transplantation 66 1998 1014 1020
24. A.J. Franko, J. Sharplin, and A. Ghahary Immunohistochemical localization of transforming growth factor beta and tumor necrosis factor alpha in the lungs of fibrosis-prone and nonfibrosing mice during the latent period and early phase after irradiation Radiat Res 147 1997 245 256
25. S.H. Phan, and S.L. Kunkel Lung cytokine production in bleomycin-induced pulmonary fibrosis Exp Lung Res 18 1992 29 43
26. Y. Nakamura, L. Tate, and R.F. Ertl Bronchial epithelial cells regulate fibroblast proliferation Am J Physiol 269 1995 L377 L387
27. A. El-Gamel, M.R. Awad, and P.S. Hasleton Transforming growth factor-beta (TGF-beta1) genotype and lung allograft fibrosis J Heart Lung Transplant 18 1999 517 523
28. P.D. Arkwright, S. Laurie, and M. Super TGF-beta(1) genotype and accelerated decline in lung function of patients with cystic fibrosis Thorax 55 2000 459 462
29. R.M. Clancy, C.B. Backer, and X. Yin Cytokine polymorphisms and histologic expression in autopsy studies: Contribution of TNFα and TGFβ1 to the pathogenesis of autoimmune-associated congenital heart block J Immunol 171 2003 3253 3261
30. V.P. Werth, W. Zhang, and K. Dortzbach Association of a promoter polymorphism of tumor necrosis factor-alpha with subacute cutaneous lupus erythematosus and distinct photoregulation of transcription J Invest Dermatol 115 2000 726 730
31. V.P. Werth, J.P. Callen, and G. Ang Associations of tumor necrosis factor alpha and HLA polymorphisms with adult dermatomyositis: implications for a unique pathogenesis J Invest Dermatol 119 2002 617 620
32. W. McGuire, A.V. Hill, and C.E. Allsopp Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria Nature 371 1994 508 510
33. K.E. Sullivan, C. Wooten, and B.J. Schmeckpeper A promoter polymorphism of tumor necrosis factor alpha associated with systemic lupus erythematosus in African-Americans Arthritis Rheum 40 1997 2207 2211
34. A.G. Wilson, N. de Vries, and F. Pociot An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles J Exp Med 177 1993 557 560
35. R.M. Clancy, C.B. Backer, and X. Yin Genetic association of cutaneous neonatal lupus with HLA class II and TNF-α: Implications for pathogenesis Arthritis Rheum 50 2004 2598 2603
36. A.D. Askanase, D.M. Friedman, and J. Copel Spectrum and progression of conduction abnormalities in infants born to mothers with anti-Ro/La antibodies Lupus 11 2002 145 151
37. E.T. Jaeggi, R.M. Hamilton, and E.D. Silverman Outcome of children with fetal, neonatal, or childhood diagnosis of isolated congenital atrioventricular block J Am Coll Cardiol 39 2002 130 137
38. L.E. Nield, E.D. Silverman, and G.P. Taylor Maternal anti-Ro and anti-La antibody-associated endocardial fibroelastosis Circulation 105 2002 843 848
39. L.E. Nield, E.D. Silverman, and J.F. Smallhorn Endocardial fibroelastosis associated with maternal anti-Ro and anti-La antibodies in the absence of atrioventricular block J Am Coll Cardiol 40 2002 796 802
40. J.S. Glickstein, J.P. Buyon, and D. Friedman The fetal PR interval: pulsed Doppler echocardiographic assessment Am J Cardiol 86 2000 236 239
41. J. Glickstein, J. Buyon, M. Kim, D. Friedman and the PRIDE investigators The fetal Doppler mechanical PR interval: a validation study Fetal Diagn Ther 19 2004 31 34
42. J. Waltuck, and J.P. Buyon Autoantibody-associated congenital heart block: outcome in mothers and children Ann Intern Med 120 1994 544 551
43. A.T. Blanford, and B.E. Pearson Murphy In vitro metabolism of prednisolone, dexamethasone, betamethasone, and cortisol by the human placenta Am J Obstet Gynecol 127 1997 264 267
44. R. Kaaja, and H. Julkunen Prevention of recurrence of congenital heart block with intravenous immunoglobulin and corticosteroid therapy: comment on the editorial by Buyon et al Arthritis Rheum 48 2003 280 281
45. A. Samuelsson, T.L. Towers, and J.V. Ravetch Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor Science 291 2001 445 446
46. S. Saleeb, J. Copel, and D. Friedman Comparison of treatment with fluorinated glucocorticoids to the natural history of autoantibody-associated congenital heart block: Retrospective review of the Research Registry for Neonatal Lupus Arthritis Rheum 42 1999 2335 2345
47. H. Matsushita, M. Higashino, and N. Sekizuka Successful prenatal treatment of congenital heart block with ritodrine administered transplacentally Arch Gynecol Obstet 267 2002 51 53
48. A.R. Neiman, L.A. Lee, and W.L. Weston Cutaneous manifestations of neonatal lupus without heart block: characteristics of mothers and children enrolled in a national registry J Pediatr 37 2002 674 680
49. A.D. Askanase, M.E. Miranda-Carus, and X. Tang The presence of IgG antibodies reactive with components of the SSA/Ro-SSB/La complex in human breast milk: implications in neonatal lupus Arthritis Rheum 46 2002 269 271