The sequelae of cranial irradiation on human cognition

Neuroscience Letters

Volumn 382, Issue 1-2, 2005, Pages 118-123

  Sarkissian, Vahé ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cognition; Female; Methotrexate; Neurogenesis; Pediatric; Radiation

Indexed keywords

ANTINEOPLASTIC AGENT; METHOTREXATE;

AGE; ARTICLE; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; COGNITION; COGNITIVE DEFECT; COGNITIVE DEVELOPMENT; GENDER; GROWTH HORMONE DEFICIENCY; HIPPOCAMPUS; HUMAN; HYPOPITUITARISM; NERVOUS SYSTEM DEVELOPMENT; NEUROTOXICITY; PRIORITY JOURNAL; RADIATION INJURY; RISK FACTOR; SKULL IRRADIATION;

AGING; BRAIN; COGNITION; COGNITION DISORDERS; FEMALE; HUMANS; MALE; RADIOTHERAPY; RISK FACTORS; SEX CHARACTERISTICS;

EID: 19444371357     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.02.068     Document Type: Article

References (122)

1. O.K. Abayomi Pathogenesis of irradiation-induced cognitive dysfunction Acta Oncol. 35 1996 659 663
2. S. Abrahams, A. Pickering, C.E. Polkey, and R.G. Morris Spatial memory deficits in patients with unilateral damage to the right hippocampal formation Neuropsychologia 35 1997 11 24
3. J. Alfonso, F. Aguero, D.O. Sanchez, G. Flugge, E. Fuchs, A.C. Frasch, and G.D. Pollevick Gene expression analysis in the hippocampal formation of tree shrews chronically treated with cortisol J. Neurosci. Res. 78 2004 702 710
4. J. Alfonso, G.D. Pollevick, M.G. Van Der Hart, G. Flugge, E. Fuchs, and A.C. Frasch Identification of genes regulated by chronic psychosocial stress and antidepressant treatment in the hippocampus Eur. J. Neurosci. 19 2004 659 666
5. V.A. Anderson, T. Godber, E. Smibert, S. Weiskop, and H. Ekert Cognitive and academic outcome following cranial irradiation and chemotherapy in children: a longitudinal study Br. J. Cancer 82 2000 255 262
6. V. Anderson, E. Smibert, H. Ekert, and T. Godber Intellectual educational, and behavioural sequelae after cranial irradiation and chemotherapy Arch. Dis. Child 70 1994 476 483
7. M.A. Andrykowski, F.A. Schmitt, M.E. Gregg, M.J. Brady, D.G. Lamb, and P.J. Henslee-Downey Neuropsychologic impairment in adult bone marrow transplant candidates Cancer 70 1992 2288 2297
8. C.L. Armstrong, K. Gyato, A.W. Awadalla, R. Lustig, and Z.A. Tochner A critical review of the clinical effects of therapeutic irradiation damage to the brain: the roots of controversy Neuropsychol. Rev. 14 2004 65 86
9. R.D. Barr, T. Simpson, A. Whitton, B. Rush, W. Furlong, and D.H. Feeny Health-related quality of life in survivors of tumours of the central nervous system in childhood - a preference-based approach to measurement in a cross-sectional study Eur. J. Cancer 35 1999 248 255
10. M. Bendersky, M. Lewis, D.E. Mandelbaum, and C. Stanger Serial neuropsychological follow-up of a child following craniospinal irradiation Dev. Med. Child Neurol. 30 1988 816 820
11. R.A. Berg, L.T. Ch'ien, W. Lancaster, S. Williams, and J. Cummins Neuropsychological sequelae of postradiation somnolence syndrome J. Dev. Behav. Pediatr. 4 1983 103 107
12. M.C. Bohn Granule cell genesis in the hippocampus of rats treated neonatally with hydrocortisone Neuroscience 5 1980 2003 2012
13. M.C. Bohn, and J.M. Lauder Cerebellar granule cell genesis in the hydrocortisone-treated rats Dev. Neurosci. 3 1980 81 89
14. J. Bradbury New targets identified for preventing cognitive decline after cranial irradiation Lancet Oncol. 3 2002 521
15. R.W. Butler, J.M. Hill, P.G. Steinherz, P.A. Meyers, and J.L. Finlay Neuropsychologic effects of cranial irradiation, intrathecal methotrexate, and systemic methotrexate in childhood cancer J. Clin. Oncol. 12 1994 2621 2629
16. R.D. Chadderton, C.G. West, S. Schuller, D.C. Quirke, R. Gattamaneni, R. Taylor, and S. Schulz Radiotherapy in the treatment of low-grade astrocytomas. II. The physical and cognitive sequelae Childs Nerv. Syst. 11 1995 443 448
17. M. Cheung, A.S. Chan, S.C. Law, J.H. Chan, and V.K. Tse Cognitive function of patients with nasopharyngeal carcinoma with and without temporal lobe radionecrosis Arch. Neurol. 57 2000 1347 1352
18. D. Christie, A.D. Leiper, J.M. Chessells, and F. Vargha-Khadem Intellectual performance after presymptomatic cranial radiotherapy for leukaemia: effects of age and sex Arch. Dis. Child 73 1995 136 140
19. C.L. Coe, M. Kramer, B. Czeh, E. Gould, A.J. Reeves, C. Kirschbaum, and E. Fuchs Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile rhesus monkeys Biol. Psychiatry 54 2003 1025 1034
20. D.R. Copeland, C. deMoor, B.D. Moore 3rd, and J.L. Ater Neurocognitive development of children after a cerebellar tumor in infancy: a longitudinal study J. Clin. Oncol. 17 1999 3476 3486
21. D.R. Copeland, J.M. Fletcher, B. Pfefferbaum-Levine, N. Jaffe, H. Ried, and M. Maor Neuropsychological sequelae of childhood cancer in long-term survivors Pediatrics 75 1985 745 753
22. P. Cousens, J.A. Ungerer, J.A. Crawford, and M.M. Stevens Cognitive effects of childhood leukemia therapy: a case for four specific deficits J. Pediatr. Psychol. 16 1991 475 488
23. P. Cousens, B. Waters, J. Said, and M. Stevens Cognitive effects of cranial irradiation in leukaemia: a survey and meta-analysis J. Child Psychol. Psychiatry 29 1988 839 852
24. J.R. Crossen, D. Garwood, E. Glatstein, and E.A. Neuwelt Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy J. Clin. Oncol. 12 1994 627 642
25. D. d'Avella, R. Cicciarello, F.F. Angileri, S. Lucerna, D. La Torre, and F. Tomasello Radiation-induced blood-brain barrier changes: pathophysiological mechanisms and clinical implications Acta Neurochir. Suppl. 71 1998 282 284
26. R.E. Dowell Jr., D.R. Copeland, D.J. Francis, J.M. Fletcher, and M. Stovall Absence of synergistic effects of CNS treatments on neuropsychologic test performance among children J. Clin. Oncol. 9 1991 1029 1036
27. C.M. Filley Toxic leukoencephalopathy Clin. Neuropharmacol. 22 1999 249 260
28. A. Garcia-Perez, J. Narbona-Garcia, L. Sierrasesumaga, M. Aguirre-Ventallo, and F. Calvo-Manuel Neuropsychological outcome of children after radiotherapy for intracranial tumours Dev. Med. Child Neurol. 35 1993 139 148
29. A. Garcia-Perez, L. Sierrasesumaga, J. Narbona-Garcia, F. Calvo-Manuel, and M. Aguirre-Ventallo Neuropsychological evaluation of children with intracranial tumors: impact of treatment modalities Med. Pediatr. Oncol. 23 1994 116 123
30. J. Giralt, J.J. Ortega, T. Olive, R. Verges, I. Forio, and L. Salvador Long-term neuropsychologic sequelae of childhood leukemia: comparison of two CNS prophylactic regimens Int. J. Radiat. Oncol. Biol. Phys. 24 1992 49 53
31. T. Godber, V. Anderson, and R. Bell The measurement and diagnostic utility of intrasubtest scatter in pediatric neuropsychology J. Clin. Psychol. 56 2000 101 112
32. J.W. Goldwein, J. Radcliffe, J. Johnson, T. Moshang, R.J. Packer, L.N. Sutton, L.B. Rorke, and G.J. D'Angio Updated results of a pilot study of low dose craniospinal irradiation plus chemotherapy for children under five with cerebellar primitive neuroectodermal tumors (medulloblastoma) Int. J. Radiat. Oncol. Biol. Phys. 34 1996 899 904
33. A. Gregor, A. Cull, E. Traynor, M. Stewart, F. Lander, and S. Love Neuropsychometric evaluation of long-term survivors of adult brain tumours: relationship with tumour and treatment parameters Radiother. Oncol. 41 1996 55 59
34. J. Grill, V. Kieffer, and C. Kalifa Measuring the neuro-cognitive side-effects of irradiation in children with brain tumors Pediatr. Blood Cancer 42 2004 452 456
35. J. Grill, V.K. Renaux, C. Bulteau, D. Viguier, C. Levy-Piebois, C. Sainte-Rose, G. Dellatolas, M.A. Raquin, I. Jambaque, and C. Kalifa Long-term intellectual outcome in children with posterior fossa tumors according to radiation doses and volumes Int. J. Radiat. Oncol. Biol. Phys. 45 1999 137 145
36. N. Guha-Thakurta, D. Damek, C. Pollack, and F.H. Hochberg Intravenous methotrexate as initial treatment for primary central nervous system lymphoma: response to therapy and quality of life of patients J. Neurooncol. 43 1999 259 268
37. J.L. Habrand, and R. De Crevoisier Radiation therapy in the management of childhood brain tumors Childs Nerv. Syst. 17 2001 121 133
38. F.E. Halberg, J.H. Kramer, I.M. Moore, W.M. Wara, K.K. Matthay, and A.R. Ablin Prophylactic cranial irradiation dose effects on late cognitive function in children treated for acute lymphoblastic leukemia Int. J. Radiat. Oncol. Biol. Phys. 22 1992 13 16
39. P. Hall, H.O. Adami, D. Trichopoulos, N.L. Pedersen, P. Lagiou, A. Ekbom, M. Ingvar, M. Lundell, and F. Granath Effect of low doses of ionising radiation in infancy on cognitive function in adulthood: Swedish population based cohort study Br. Med. J. 328 2004 19
40. J.M. Hill, A.B. Kornblith, D. Jones, A. Freeman, J.F. Holland, A.S. Glicksman, J.M. Boyett, B. Lenherr, M.L. Brecher, R. Dubowy, F. Kung, H. Maurer, and J.C. Holland A comparative study of the long term psychosocial functioning of childhood acute lymphoblastic leukemia survivors treated by intrathecal methotrexate with or without cranial radiation Cancer 82 1998 208 218
41. E. Huang, B.S. Teh, D.R. Strother, Q.G. Davis, J.K. Chiu, H.H. Lu, L.S. Carpenter, W.Y. Mai, M.M. Chintagumpala, M. South, W.H. Grant 3rd, E.B. Butler, and S.Y. Woo Intensity-modulated radiation therapy for pediatric medulloblastoma: early report on the reduction of ototoxicity Int. J. Radiat. Oncol. Biol. Phys. 52 2002 599 605
42. M.C. Hulshof, N.M. Stark, A. van der Kleij, P. Sminia, H.M. Smeding, and D. Gonzalez Gonzalez Hyperbaric oxygen therapy for cognitive disorders after irradiation of the brain Strahlenther. Onkol. 178 2002 192 198
43. K. Itoi, Y.Q. Jiang, Y. Iwasaki, and S.J. Watson Regulatory mechanisms of corticotropin-releasing hormone and vasopressin gene expression in the hypothalamus J. Neuroendocrinol. 16 2004 348 355
44. L. Iuvone, P. Mariotti, C. Colosimo, F. Guzzetta, A. Ruggiero, and R. Riccardi Long-term cognitive outcome, brain computed tomography scan, and magnetic resonance imaging in children cured for acute lymphoblastic leukemia Cancer 95 2002 2562 2570
45. Y. Jain, V.P. Choudhry, L.S. Arya, and M. Mehta Neuropsychological abnormalities following CNS prophylaxis in children with acute lymphatic leukemia Indian J. Pediatr. 60 1993 675 681
46. T. Kadar, M. Silbermann, R. Brandeis, and A. Levy Age-related structural changes in the rat hippocampus: correlation with working memory deficiency Brain Res. 512 1990 113 120
47. T.A. Kaleita, G.H. Reaman, W.E. MacLean, H.N. Sather, and J.K. Whitt Neurodevelopmental outcome of infants with acute lymphoblastic leukemia: a Children's Cancer Group report Cancer 85 1999 1859 1865
48. G. Kempermann, L. Wiskott, and F.H. Gage Functional significance of adult neurogenesis Curr. Opin. Neurobiol. 14 2004 186 191
49. A. Kingma, R.I. van Dommelen, E.L. Mooyaart, J.T. Wilmink, B.G. Deelman, and W.A. Kamps Slight cognitive impairment and magnetic resonance imaging abnormalities but normal school levels in children treated for acute lymphoblastic leukemia with chemotherapy only J. Pediatr. 139 2001 413 420
50. M. Klein, J.J. Heimans, N.K. Aaronson, H.M. van der Ploeg, J. Grit, M. Muller, T.J. Postma, J.J. Mooij, R.H. Boerman, G.N. Beute, G.J. Ossenkoppele, G.W. van Imhoff, A.W. Dekker, J. Jolles, B.J. Slotman, H. Struikmans, and M.J. Taphoorn Effect of radiotherapy and other treatment-related factors on mid-term to long-term cognitive sequelae in low-grade gliomas: a comparative study Lancet 360 2002 1361 1368
51. T. Langer, P. Martus, H. Ottensmeier, H. Hertzberg, J.D. Beck, and W. Meier CNS late-effects after ALL therapy in childhood. Part III: neuropsychological performance in long-term survivors of childhood ALL: impairments of concentration, attention, and memory Med. Pediatr. Oncol. 38 2002 320 328
52. N. Le Marec, M. Dahhaoui, T. Stelz, A. Bakalian, N. Delhaye-Bouchaud, J. Caston, and J. Mariani Effect of cerebellar granule cell depletion on spatial learning and memory and in an avoidance conditioning task: studies in postnatally X-irradiated rats Brain Res. Dev. Brain Res. 99 1997 20 28
53. P.W. Lee, B.K. Hung, E.K. Woo, P.T. Tai, and D.T. Choi Effects of radiation therapy on neuropsychological functioning in patients with nasopharyngeal carcinoma J. Neurol. Neurosurg. Psychiatry 52 1989 488 492
54. Y.Q. Li, J.R. Ballinger, R.A. Nordal, Z.F. Su, and C.S. Wong Hypoxia in radiation-induced blood-spinal cord barrier breakdown Cancer Res. 61 2001 3348 3354
55. Z. Li, C.H. Kim, J. Ichikawa, and H.Y. Meltzer Effect of repeated administration of phencyclidine on spatial performance in an eight-arm radial maze with delay in rats and mice Pharmacol. Biochem. Behav. 75 2003 335 340
56. A.M. Lilja, R.I. Portin, P.I. Hamalainen, and E.K. Salminen Short-term effects of radiotherapy on attention and memory performances in patients with brain tumors Cancer 91 2001 2361 2368
57. C.L. Limoli, E. Giedzinski, R. Rola, S. Otsuka, T.D. Palmer, and J.R. Fike Radiation response of neural precursor cells: linking cellular sensitivity to cell cycle checkpoints, apoptosis and oxidative stress Radiat. Res. 161 2004 17 27
58. H. Liu, J. Kaur, K. Dashtipour, R. Kinyamu, C.E. Ribak, and L.K. Friedman Suppression of hippocampal neurogenesis is associated with developmental stage, number of perinatal seizure episodes, and glucocorticosteroid level Exp. Neurol. 184 2003 196 213
59. L.D. Lunsford, and D. Kondziolka Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients Neurology 57 2001 2150 2151
60. M. Macedoni-Luksic, B. Jereb, and L. Todorovski Long-term sequelae in children treated for brain tumors: impairments, disability, and handicap Pediatr. Hematol. Oncol. 20 2003 89 101
61. W.E. MacLean Jr., R.B. Noll, J.A. Stehbens, T.A. Kaleita, E. Schwartz, J.K. Whitt, N.L. Cantor, M. Waskerwitz, F. Ruymann, and L.J. Novak Neuropsychological effects of cranial irradiation in young children with acute lymphoblastic leukemia 9 months after diagnosis. The Children's Cancer Group Arch. Neurol. 52 1995 156 160
62. P.D. Maguire, R. Clough, A.H. Friedman, and E.C. Halperin Fractionated external-beam radiation therapy for meningiomas of the cavernous sinus Int. J. Radiat. Oncol. Biol. Phys. 44 1999 75 79
63. M. Marx, T. Langer, J.D. Beck, and H.G. Dorr Disorders of endocrine function after brain tumor therapy in childhood Strahlenther. Onkol. 175 1999 305 308
64. A.T. Meadows, J. Gordon, D.J. Massari, P. Littman, J. Fergusson, and K. Moss Declines in IQ scores and cognitive dysfunctions in children with acute lymphocytic leukaemia treated with cranial irradiation Lancet 2 1981 1015 1018
65. J.I. Mechanick, F.H. Hochberg, and A. LaRocque Hypothalamic dysfunction following whole-brain irradiation J. Neurosurg. 65 1986 490 494
66. M.P. Mehta, W.R. Shapiro, M.J. Glantz, R.A. Patchell, M.A. Weitzner, C.A. Meyers, C.J. Schultz, W.H. Roa, M. Leibenhaut, J. Ford, W. Curran, S. Phan, J.A. Smith, R.A. Miller, and M.F. Renschler Lead-in phase to randomized trial of motexafin gadolinium and whole-brain radiation for patients with brain metastases: centralized assessment of magnetic resonance imaging, neurocognitive, and neurologic end points J. Clin. Oncol. 20 2002 3445 3453
67. T.E. Merchant, L. Happersett, J.L. Finlay, and S.A. Leibel Preliminary results of conformal radiation therapy for medulloblastoma Neuro-oncolology 1 1999 177 187
68. C.A. Meyers, F. Geara, P.F. Wong, and W.H. Morrison Neurocognitive effects of therapeutic irradiation for base of skull tumors Int. J. Radiat. Oncol. Biol. Phys. 46 2000 51 55
69. M. Moleski Neuropsychological, neuroanatomical, and neurophysiological consequences of CNS chemotherapy for acute lymphoblastic leukemia Arch. Clin. Neuropsychol. 15 2000 603 630
70. M.L. Monje, S. Mizumatsu, J.R. Fike, and T.D. Palmer Irradiation induces neural precursor-cell dysfunction Nat. Med. 8 2002 955 962
71. M.L. Monje, and T. Palmer Radiation injury and neurogenesis Curr. Opin. Neurol. 16 2003 129 134
72. M.L. Monje, H. Toda, and T.D. Palmer Inflammatory blockade restores adult hippocampal neurogenesis Science 302 2003 1760 1765
73. B.D. Moore 3rd, J.L. Ater, and D.R. Copeland Improved neuropsychological outcome in children with brain tumors diagnosed during infancy and treated without cranial irradiation J. Child Neurol. 7 1992 281 290
74. I.M. Moore, J.H. Kramer, W. Wara, F. Halberg, and A.R. Ablin Cognitive function in children with leukemia. Effect of radiation dose and time since irradiation Cancer 68 1991 1913 1917
75. R.K. Mulhern Correlation of the Health Utilities Index Mark 2 cognition scale and neuropsychological functioning among survivors of childhood medulloblastoma Int. J. Cancer Suppl. 12 1999 91 94
76. R.K. Mulhern, and R.W. Butler Neurocognitive sequelae of childhood cancers and their treatment Pediatr. Rehabil. 7 2004 1 14 (discussion 15-16)
77. R.K. Mulhern, J.L. Kepner, P.R. Thomas, F.D. Armstrong, H.S. Friedman, and L.E. Kun Neuropsychologic functioning of survivors of childhood medulloblastoma randomized to receive conventional or reduced-dose craniospinal irradiation: a Pediatric Oncology Group study J. Clin. Oncol. 16 1998 1723 1728
78. R.K. Mulhern, E.H. Kovnar, L.E. Kun, J.J. Crisco, and J.M. Williams Psychologic and neurologic function following treatment for childhood temporal lobe astrocytoma J. Child Neurol. 3 1988 47 52
79. R.K. Mulhern, and L.E. Kun Neuropsychologic function in children with brain tumors: III. Interval changes in the six months following treatment Med. Pediatr. Oncol. 13 1985 318 324
80. R.K. Mulhern, T.E. Merchant, A. Gajjar, W.E. Reddick, and L.E. Kun Late neurocognitive sequelae in survivors of brain tumours in childhood Lancet Oncol. 5 2004 399 408
81. R.K. Mulhern, S.L. Palmer, W.E. Reddick, J.O. Glass, L.E. Kun, J. Taylor, J. Langston, and A. Gajjar Risks of young age for selected neurocognitive deficits in medulloblastoma are associated with white matter loss J. Clin. Oncol. 19 2001 472 479
82. M.P. Nahum, M. Gdal-On, A. Kuten, G. Herzl, Y. Horovitz, and M. Weyl Ben Arush Long-term follow-up of children with retinoblastoma Pediatr. Hematol. Oncol. 18 2001 173 179
83. R.A. Nordal, A. Nagy, M. Pintilie, and C.S. Wong Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor Clin. Cancer Res 10 2004 3342 3353
84. R.A. Nordal, and C.S. Wong Intercellular adhesion molecule-1 and blood-spinal cord barrier disruption in central nervous system radiation injury J. Neuropathol. Exp. Neurol. 63 2004 474 483
85. B.K. Ormerod, T.T. Lee, and L.A. Galea Estradiol initially enhances but subsequently suppresses (via adrenal steroids) granule cell proliferation in the dentate gyrus of adult female rats J. Neurobiol. 55 2003 247 260
86. S.L. Palmer, O. Goloubeva, W.E. Reddick, J.O. Glass, A. Gajjar, L. Kun, T.E. Merchant, and R.K. Mulhern Patterns of intellectual development among survivors of pediatric medulloblastoma: a longitudinal analysis J. Clin. Oncol. 19 2001 2302 2308
87. P. Parth, W.P. Dunlap, R.S. Kennedy, J.M. Ordy, and N.E. Lane Motor and cognitive testing of bone marrow transplant patients after chemoradiotherapy Percept. Mot. Skills. 68 1989 1227 1241
88. A.C. Paulino, J.H. Simon, W. Zhen, and B.C. Wen Long-term effects in children treated with radiotherapy for head and neck rhabdomyosarcoma Int. J. Radiat. Oncol. Biol. Phys. 48 2000 1489 1495
89. M. Peper, S. Steinvorth, P. Schraube, S. Fruehauf, R. Haas, B.N. Kimmig, F. Lohr, F. Wenz, and M. Wannenmacher Neurobehavioral toxicity of total body irradiation: a follow-up in long-term survivors Int. J. Radiat. Oncol. Biol. Phys. 46 2000 303 311
90. B. Pfefferbaum-Levine, D.R. Copeland, J.M. Fletcher, H.L. Ried, N. Jaffe, and W.R. McKinnon Jr. Neuropsychologic assessment of long-term survivors of childhood leukemia Am. J. Pediatr. Hematol. Oncol. 6 1984 123 128
91. E.K. Polston, G. Gu, and R.B. Simerly Neurons in the principal nucleus of the bed nuclei of the stria terminalis provide a sexually dimorphic GABAergic input to the anteroventral periventricular nucleus of the hypothalamus Neuroscience 123 2004 793 803
92. S. Precourt, P. Robaey, I. Lamothe, M. Lassonde, H.C. Sauerwein, and A. Moghrabi Verbal cognitive functioning and learning in girls treated for acute lymphoblastic leukemia by chemotherapy with or without cranial irradiation Dev. Neuropsychol. 21 2002 173 195
93. J. Raber, R. Rola, A. LeFevour, D. Morhardt, J. Curley, S. Mizumatsu, S.R. VandenBerg, and J.R. Fike Radiation-induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesis Radiat. Res. 162 2004 39 47
94. J. Radcliffe, G.R. Bunin, L.N. Sutton, J.W. Goldwein, and P.C. Phillips Cognitive deficits in long-term survivors of childhood medulloblastoma and other noncortical tumors: age-dependent effects of whole brain radiation Int. J. Dev. Neurosci. 12 1994 327 334
95. W.F. Regine, C. Scott, K. Murray, and W. Curran Neurocognitive outcome in brain metastases patients treated with accelerated-fractionation vs. accelerated-hyperfractionated radiotherapy: an analysis from Radiation Therapy Oncology Group Study 91-04 Int. J. Radiat. Oncol. Biol. Phys. 51 2001 711 717
96. T.S. Reimers, S. Ehrenfels, E.L. Mortensen, M. Schmiegelow, S. Sonderkaer, H. Carstensen, K. Schmiegelow, and J. Muller Cognitive deficits in long-term survivors of childhood brain tumors: identification of predictive factors Med. Pediatr. Oncol. 40 2003 26 34
97. D. Riva, and C. Giorgi The neurodevelopmental price of survival in children with malignant brain tumours Childs Nerv. Syst. 16 2000 751 754
98. D.D. Roman, and P.W. Sperduto Neuropsychological effects of cranial radiation: current knowledge and future directions Int. J. Radiat. Oncol. Biol. Phys. 31 1995 983 998
99. R.C. Rostomily, J. Halligan, R. Geyer, K. Stelzer, K. Lindsley, and M.S. Berger Permanent low-activity (125)I seed placement for the treatment of pediatric brain tumors: preliminary experience Pediatr. Neurosurg. 34 2001 198 205
100. J.H. Rowland, O.J. Glidewell, R.F. Sibley, J.C. Holland, R. Tull, A. Berman, M.L. Brecher, M. Harris, A.S. Glicksman, and E. Forman Effects of different forms of central nervous system prophylaxis on neuropsychologic function in childhood leukemia J. Clin. Oncol. 2 1984 1327 1335
101. A. Schaffer, and J.J. Jeffries Delayed cognitive decline following cranial irradiation Can. J. Psychiatry 44 1999 605
102. A.E. Schlieper, D.W. Esseltine, and E. Tarshis Cognitive function in long survivors of childhood acute lymphoblastic leukemia Pediatr. Hematol. Oncol. 6 1989 1 9
103. E. Seaver, R. Geyer, S. Sulzbacher, M. Warner, L. Batzel, J. Milstein, and M. Berger Psychosocial adjustment in long-term survivors of childhood medulloblastoma and ependymoma treated with craniospinal irradiation Pediatr. Neurosurg. 20 1994 248 253
104. N. Senzer Rationale for a phase III study of erythropoietin as a neurocognitive protectant in patients with lung cancer receiving prophylactic cranial irradiation Semin. Oncol. 29 2002 47 52
105. E. Smibert, V. Anderson, T. Godber, and H. Ekert Risk factors for intellectual and educational sequelae of cranial irradiation in childhood acute lymphoblastic leukaemia Br. J. Cancer 73 1996 825 830
106. B.J. Spiegler, E. Bouffet, M.L. Greenberg, J.T. Rutka, and D.J. Mabbott Change in neurocognitive functioning after treatment with cranial radiation in childhood J. Clin. Oncol. 22 2004 706 713
107. E. Suc, C. Kalifa, R. Brauner, J.L. Habrand, M.J. Terrier-Lacombe, G. Vassal, and J. Lemerle Brain tumours under the age of three. The price of survival. A retrospective study of 20 long-term survivors Acta Neurochir. (Wien) 106 1990 93 98
108. O. Surma-aho, M. Niemela, J. Vilkki, M. Kouri, A. Brander, O. Salonen, A. Paetau, M. Kallio, J. Pyykkonen, and J. Jaaskelainen Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients Neurology 56 2001 1285 1290
109. I. Syndikus, D. Tait, S. Ashley, and L. Jannoun Long-term follow-up of young children with brain tumors after irradiation Int. J. Radiat. Oncol. Biol. Phys. 30 1994 781 787
110. E. Tada, J.M. Parent, D.H. Lowenstein, and J.R. Fike X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats Neuroscience 99 2000 33 41
111. M.H. Teicher, S.L. Andersen, A. Polcari, C.M. Anderson, and C.P. Navalta Developmental neurobiology of childhood stress and trauma Psychiatr. Clin. North Am. 25 2002 397 426 vii-viii
112. H.G. Terheggen, and M. Rado Non-leukemic disease of the central nervous system in children with acute lymphoblastic leukemia. I. Somnolence syndrome (author's transl) Monatsschr. Kinderheilkd. 126 1978 693 695
113. A.A. Toogood Endocrine consequences of brain irradiation Growth Horm IGF Res. 14 Suppl. A 2004 118 124
114. M.N. Tsao, Y.Q. Li, G. Lu, Y. Xu, and C.S. Wong Upregulation of vascular endothelial growth factor is associated with radiation-induced blood-spinal cord barrier breakdown J. Neuropathol. Exp. Neurol. 58 1999 1051 1060
115. 1H nuclear magnetic resonance spectroscopy in vivo Int. J. Radiat. Oncol. Biol. Phys. 33 1995 719 724
116. A.G. van Oosterhout, P.J. Boon, P.J. Houx, G.P. ten Velde, and A. Twijnstra Follow-up of cognitive functioning in patients with small cell lung cancer Int. J. Radiat. Oncol. Biol. Phys. 31 1995 911 914
117. A. Virta, N. Patronas, R. Raman, A. Dwyer, A. Barnett, S. Bonavita, G. Tedeschi, and N. Lundbom Spectroscopic imaging of radiation-induced effects in the white matter of glioma patients Magn. Reson. Imaging 18 2000 851 857
118. D.P. Waber, B.L. Shapiro, S.C. Carpentieri, R.D. Gelber, G. Zou, A. Dufresne, I. Romero, N.J. Tarbell, L.B. Silverman, and S.E. Sallan Excellent therapeutic efficacy and minimal late neurotoxicity in children treated with 18 grays of cranial radiation therapy for high-risk acute lymphoblastic leukemia: a 7-year follow-up study of the Dana-Farber Cancer Institute Consortium Protocol 87-01 Cancer 92 2001 15 22
119. D.P. Waber, N.J. Tarbell, C.M. Kahn, R.D. Gelber, and S.E. Sallan The relationship of sex and treatment modality to neuropsychologic outcome in childhood acute lymphoblastic leukemia J. Clin. Oncol. 10 1992 810 817
120. D.P. Waber, D.K. Urion, N.J. Tarbell, C. Niemeyer, R. Gelber, and S.E. Sallan Late effects of central nervous system treatment of acute lymphoblastic leukemia in childhood are sex-dependent Dev. Med. Child Neurol. 32 1990 238 248
121. M.W. Wassenberg, J.E. Bromberg, T.D. Witkamp, C.H. Terhaard, and M.J. Taphoorn White matter lesions and encephalopathy in patients treated for primary central nervous system lymphoma J. Neurooncol. 52 2001 73 80
122. M. Yamada, H. Sasaki, F. Kasagi, M. Akahoshi, Y. Mimori, K. Kodama, and S. Fujiwara Study of cognitive function among the Adult Health Study (AHS) population in Hiroshima and Nagasaki Radiat. Res. 158 2002 236 240