Genetic analysis of the antibody response to AAV2 and factor IX

Molecular Therapy

Volumn 11, Issue 6, 2005, Pages 866-874

  Zhang, Huang Ge ^a,b   High, Katherine A ^c   Wu, Qi ^a   Yang, PingAr ^a   Schlachterman, Alex ^c   Yu, Shaohua ^a   Yi, Nengjun ^d   Hsu, Hui Chen ^a   Mountz, John D ^a,b  

^a University of Alabama at Birmingham   (United States)

^b BIRMINGHAM VA MEDICAL CENTER   (United States)

^c HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

AAV; Antibody; BXD recombinant inbred mice; Factor IX; Genetic linkage analysis; Genetic susceptibility; Hemophilia B; Immune modulation

Indexed keywords

ALPHA 1 ANTITRYPSIN; APOLIPOPROTEIN E; BETA GLOBIN; BLOOD CLOTTING FACTOR 9; COMPLEMENTARY DNA; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2B; PARVOVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; FEMALE; GENE INTERACTION; GENE LOCUS; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC REGULATION; INBRED STRAIN; LINKAGE ANALYSIS; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; STATISTICAL SIGNIFICANCE; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID;

ALLELES; ANIMALS; ANTIBODIES, VIRAL; CAPSID; DEPENDOVIRUS; DOGS; EPISTASIS, GENETIC; FACTOR IX; FEMALE; GENETIC VECTORS; IMMUNOGLOBULIN G; INJECTIONS, INTRAVENOUS; MICE; MICE, INBRED STRAINS; QUANTITATIVE TRAIT LOCI;

MIRIDAE;

EID: 19444364872     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.02.014     Document Type: Article

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