Differential modulation of ATP-induced calcium signalling by A1 and A2 adenosine receptors in cultured cortical astrocytes

British Journal of Pharmacology

Volumn 141, Issue 6, 2004, Pages 935-942

  Alloisio, Susanna ^a   Cugnoli, Carlo ^a   Ferroni, Stefano ^b   Nobile, Mario ^a  

^a CNR   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Adenosine receptors; Astroglia; Calcium homeostasis; Microfluorimetry; P2 purinoceptors

Indexed keywords

1 DEOXY 1 [6 [[(3 IODOPHENYL)METHYL]AMINO] 9H PURIN 9 YL] N METHYL BETA DEXTRO RIBOFURANURONAMIDE AGONIST; 1,3 DIETHYL 8 PHENYLXANTHINE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2 CHLOROADENOSINE; 3' O (4 BENZOYLBENZOYL)ADENOSINE TRIPHOSPHATE; ADENINE NUCLEOTIDE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR; ADENOSINE A2 RECEPTOR AGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; ADENOSINE TRIPHOSPHATE; CALCIUM; METABOTROPIC RECEPTOR AGONIST; MRS 1706; N (4 ACETYLPHENYL) 2 [4 (2,3,6,7 TETRAHYDRO 2,6 DIOXO 1,3 DIPROPYL 1H PURIN 8 YL)PHENOXY]ACETAMIDE; PERTUSSIS TOXIN; PHENYLISOPROPYLADENOSINE; PURINE P2 RECEPTOR; PURINE P2Y RECEPTOR; PURINE P2Y1 RECEPTOR; PURINE P2Y2 RECEPTOR; PURINE P2Y4 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN CORTEX; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL DIFFERENTIATION; DRUG POTENTIATION; DRUG SELECTIVITY; MICROFLUOROMETRY; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; RAT;

2-CHLOROADENOSINE; ADENOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; ASTROCYTES; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; CYCLIC AMP; DOWN-REGULATION; RATS; RECEPTORS, PURINERGIC P1;

EID: 1942536549     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705707     Document Type: Article

References (50)

1. ABBRACCHIO, M.P. & BURNSTOCK, G. (1998). Purinergic signalling: pathophysiological roles. Jpn. J. Pharmacol., 78, 113-145.
2. ABBRACCHIO, M.P., CERUTI, S., BARBIERI, D., FRANCESCHI, C., MALORNI, W., BIONDO, L., BURNSTOCK, G. & CATTABENI, F. (1995). A novel action for adenosine: apoptosis of astroglial cells in rat brain primary cultures. Biochem. Biophys. Res. Commun., 213, 908-915.
3. ABBRACCHIO, M.P., SAFFREY, M.J., HOPKER, V. & BURNSTOCK, G. (1994). Modulation of astroglial cell proliferation by analogues of adenosine and ATP in primary cultures of rat striatum. Neuroscience, 59, 67-76.
4. AMADIO, S., D'AMBROSI, N., CAVALIERE, F., MURRA, B., SANCESARIO, G., BERNARDI, G., BURNSTOCK, G. & VOLONTE, C. (2002). P2 receptor modulation and cytotoxic function in cultured CNS neurons. Neuropharmacology, 42, 489-501.
5. BALLARIN, M., FREDHOLM, B.B., AMBROSIO, S. & MAHY, N. (1991). Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism. Acta Physiol. Scand., 142, 97-103.
6. 7) receptors regulate intracellular calcium and purine release. Neuroreport, 7, 2533-2537.
7. BERRIDGE, M.J., LIPP, P. & BOOTMAN, M.D. (2000). The versatility and universality of calcium signalling. Nat. Rev. Mol. Cell. Biol., 1, 11-21.
8. CORMIER, R.J., MENNERICK, S., MELBOSTAD, H. & ZORUMSKI, C.F. (2001). Basal levels of adenosine modulate mGluR5 on rat hippocampal astrocytes. Glia, 33, 24-35.
9. CUNHA, R.A., JOHANSSON, B., VAN DER PLOEG, I., SEBASTIAO, A.M., RIBEIRO, J.A. & FREDHOLM, B.B. (1994). Evidence for functionally important adenosine A2A reeptors in the rat hippocampus. Brain Res., 649, 208-216.
10. 2+ concentration in mouse astrocytes by NK1 tachykinin and adenosine agonists. J. Neurochem., 57, 2026-2035.
11. DI IORIO, P., KLEYWEGT, S., CICCARELLI, R., TRAVERSA, U., ANDREW, C.M., Crocker, C.E., WERSTIUK, E.S. & RATHBONE, M.P. (2002). Mechanisms of apoptosis induced by purine nucleosides in astrocytes. Glia, 38, 179-190.
12. 2+ response amplitude and duration. Nature, 386, 855-858.
13. FERRONI, S., MARCHINI, C., SCHUBERT, P. & RAPISARDA, C. (1995). Two distinct inwardly rectifying conductances are expressed in long term dibutyryl-cyclic-AMP treated rat cultured cortical astrocytes. FEBS Lett., 367, 319-325.
14. FERRONI, S., MARCHINI, C., OGATA, T. & SCHUBERT, P. (2002). Recovery of deficient cholinergic calcium signaling by adenosine in cultured rat cortical astrocytes. J. Neurosci. Res., 68, 615-621.
15. FRANKE, H., GROSCHE, J., SCHADLICH, H., KRUGEL, U., ALLGAIER, C. & ILLES, P. (2001a). P2X receptor expression on astrocytes in the nucleus accumbens of rats. Neuroscience, 108, 421-429.
16. FRANKE, H., KRUGEL, U. & ILLES, P. (1999). P2 receptor-mediated proliferative effects on astrocytes in vivo. Glia, 28, 190-200.
17. FRANKE, H., KRUGEL, U., SCHMIDT, R., GROSCHE, J., REICHENBACH, A. & ILLES, P. (2001b). P2 receptor-types involved in astrogliosis in vivo. Br. J. Pharmacol., 134, 1180-1189.
18. FREDHOLM, B.B. (1997). Adenosine and neuroprotection. Int. Rev. Neurobiol., 40, 259-280.
19. FUMAGALLI, M., BRAMBILLA, R., D'AMBROSI, N., VOLONTE, C., MATTEOLI, M., VERDERIO, C. & ABBRACCHIO, M.P. (2003). Nucleotide-mediated calcium signaling in rat cortical astrocytes: role of P2X and P2Y receptors. Glia, 43, 218-230.
20. GAO, Z., CHEN, T., WEBER, M.J. & LINDEN, J. (1999). A2B adenosine and P2Y2 receptors stimulate mitogen-activated protein kinase in human embryonic kidney-293 cells cross-talk between cyclic AMP and protein kinase c pathways. J. Biol. Chem., 274, 5972-5980.
21. GERWINS, P. & FREDHOLM, B.B. (1992). ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line. J. Biol. Chem., 267, 16081-16087.
22. HUNG, A.C. & SUN, S.H. (2002). The P2X(7) receptor-mediated phospholipase D activation is regulated by both PKC-dependent and PKC-independent pathways in a rat brain-derived type-2 astrocyte cell line, RBA-2. Cell Signal., 14, 83-92.
23. ILLES, P., NORENBERG, W. & GEBICKE-HAERTER, P.J. (1996). Molecular mechanisms of microglial activation. B. Voltage- and purinoceptor-operated channels in microglia. Neurochem. Int., 29, 13-24.
24. 2+ signalling in glial cell pathology in the central nervous system. Eur. J. Pharmacol., 447, 247-260.
25. JIMÉNEZ, A.I., CASTRO, E., COMMUNI, D., BOEYNAEMS, J.M., DELICADO, E.G. & MIRAS-PORTUGAL, M.T. (2000). Coexpression of several types of metabotropic nucleotide receptors in single cerebellar astrocytes. J. Neurochem., 75, 2071-2079.
26. JIMÉNEZ, A.I., CASTRO, E., DELICADO, E.G. & MIRAS-PORTUGAL, M.T. (1998). Potentiation of adenosine 5′-triphosphate calcium responses by diadenosine pentaphosphate in individual rat cerebellar astrocytes. Neurosci. Lett., 246, 109-111.
27. JIMÉNEZ, A.I., CASTRO, E., MIRABET, M., FRANCO, R., DELICADO, E.G. & MIRAS-PORTUGAL, M.T. (1999). Potentiation of ATP calcium responses by A2B receptor stimulation and other signals coupled to Gs proteins in type-1 cerebellar astrocytes. Glia, 26, 119-128.
28. KING, B.F., NEARY, J.T., ZHU, Q., WANG, S., NORENBERG, M.D. & BURNSTOCK, G. (1996). P2 purinoceptors in rat cortical astrocytes: expression, calcium-imaging and signalling studies. Neuroscience, 74, 1187-1196.
29. LEE, K.S., SCHUBERT, P., REDDINGTON, M. & KREUTZBERG, G.W. (1983). Adenosine receptor density and the depression of evoked neuronal activity in the rat hippocampus in vitro. Neurosci. Lett., 37, 81-85.
30. 1 adenosine receptors. FASEB J., 5, 2668-2676.
31. NEARY, J.T., RATHBONE, M.P., CATTABENI, F., ABBRACCHIO, M.P. & BURNSTOCK, G. (1996). Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells. Trends Neurosci., 19, 13-18.
32. NOBILE, M., MONALDI, I., ALLOISIO, S., CUGNOLI, C. & FERRONI, S. (2003). ATP-induced, sustained calcium signalling in cultured rat cortical astrocytes: evidence for a non-capacitative, P2X7-like-mediated calcium entry. FEBS Lett., 538, 71-76.
33. 2+-related A1/A2 adenosine receptor cooperation. Eur. J. Neurosci., 8, 1124-1131.
34. 2+ mobilization in conjunction with metabotropic glutamate receptor activation by t-ACPD in cultured hippocampal astrocytes. Neurosci. Lett., 170, 5-8.
35. PANENKA, W., JIJON, H., HERX, L.M., ARMSTRONG, J.N., FEIGHAN, D., WEI, T., YONG, V.W., RANSOHOFF, R.M. & MACVICAR, B.A. (2001). P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. J. Neurosci., 21, 7135-7142.
36. PAREKH, A.B. & PENNER, R. (1997). Store depletion and calcium influx. Physiol. Rev., 77, 901-930.
37. PARKINSON, F.E., SINCLAIR, C.J., OTHMAN, T., HAUGHEY, N.J. & GEIGER, J.D. (2002). Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditions. Neuropharmacology, 43, 836-846.
38. PARKINSON, F.E., ZHANG, Y.W., SHEPEL, P.N., GREENWAY, S.C., PEELING, J. & GEIGER, J.D. (2000). Effects of nitrobenzylthioinosine on neuronal injury, adenosine levels, and adenosine receptor activity in rat forebrain ischemia. J. Neurochem., 75, 795-802.
39. RALEVIC, V. & BURNSTOCK, G. (1998). Receptors for purines and pyrimidines. Pharmacol. Rev., 50, 413-492.
40. RATHBONE, M.P., MIDDLEMISS, P.J., GYSBERS, J.W., ANDREW, C., HERMAN, M.A., REED, J.K., CICCARELLI, R., DI IORIO, P. & CACIAGLI, F. (1999). Trophic effects of purines in neurons and glial cells. Prog. Neurobiol., 59, 663-690.
41. RIBEIRO, J.A., SEBASTIAO, A.M. & DE MENDONCA, A. (2002). Adenosine receptors in the nervous system: pathophysiological implications. Prog. Neurobiol., 68, 377-392.
42. SCHUBERT, P., OGATA, T., MARCHINI, C., FERRONI, S. & RUDOLPHI, K. (1997). Protective mechanisms of adenosine in neurons and glial cells. Ann. N. Y. Acad. Sci., 825, 1-10.
43. SCHUBERT, P., RUDOLPHI, K.A., FREDHOLM, B.B. & NAKAMURA, Y. (1994). Modulation of nerve and glial function by adenosine: role in the development of ischemic damage. Int. J. Biochem., 26, 1227-1236.
44. 7 receptors. J. Neurochem., 73, 334-343.
45. TOMURA, H., ITOH, H., SHO, K., SATO, K., NAGAO, M., UI, M., KONDO, Y. & OKAJIMA, F. (1997). Betagamma subunits of pertussis toxin-sensitive G proteins mediate A1 adenosine receptor agonist-induced activation of phospholipase C in collaboration with thyrotropin. A novel stimulatory mechanism through the cross-talk of two types of receptors. J. Biol. Chem., 272, 23130-23137.
46. VAN CALKER, D., MULLER, M. & HAMPRECHT, B. (1979). Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells. J. Neurochem., 33, 999-1005.
47. VERKHRATSKY, A., ORKAND, R.K. & KETTENMANN, H. (1998). Glial calcium: homeostasis and signaling function. Physiol. Rev., 78, 99-141.
48. 2+ entry in cultured rat cerebellar astrocytes. J. Neurochem., 73, 1318-1328.
49. 2+ interplay: a matter of oscillation patterns. TRENDS Neurosci., 26, 53-55.
50. ZHOU, Q.Y., LI, C., OLAH, M.E., JOHNSON, R.A., STILES, G.L. & CIVELLI, O. (1992). Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor. Proc. Natl. Acad. Sci. U.S.A. 89, 7432-7436.