Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors

GLIA

Volumn 43, Issue 3, 2003, Pages 218-230

  Fumagalli, Marta ^a   Brambilla, Roberta ^a   D'Ambrosi, Nadia ^b   Volonté, Cinzia ^b   Matteoli, Michela ^c   Verderio, Claudia ^c   Abbracchio, Maria P ^a,c  

^a UNIVERSITY OF MILAN   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c Dept of Pharmacological Sciences ^*

Author keywords

Adenine and uridine nucleotides; Astrocytes; Calcium signaling; P2X receptors; P2Y receptors; UDP glucose

Indexed keywords

2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; CALCIUM ION; NUCLEOTIDE; PURINE P2X RECEPTOR; PURINE P2X1 RECEPTOR; PURINE P2X2 RECEPTOR; PURINE P2X3 RECEPTOR; PURINE P2X4 RECEPTOR; PURINE P2X5 RECEPTOR; PURINE P2X6 RECEPTOR; PURINE P2X7 RECEPTOR; PURINE P2Y RECEPTOR; PURINE P2Y1 RECEPTOR; PURINE P2Y12 RECEPTOR; PURINE P2Y14 RECEPTOR; PURINE P2Y2 RECEPTOR; PURINE P2Y4 RECEPTOR; PURINE P2Y6 RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SURAMIN; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCOSE; URIDINE DIPHOSPHATE GLUCOSE RECEPTOR; URIDINE TRIPHOSPHATE;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN CORTEX; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL COMMUNICATION; CONTROLLED STUDY; IMAGE ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CALCIUM SIGNALING; CELLS, CULTURED; CEREBRAL CORTEX; HOMEOSTASIS; NUCLEOTIDES; RATS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PURINERGIC P2;

EID: 0041864078     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.10248     Document Type: Article

References (51)

1. Abbracchio MP, Burnstock G. 1994. Purinoceptors: are there families of P2X and P2Y purinoceptors? Pharm Ther 64:445-475.
2. 14 receptor) adds diversity to the P2Y receptor family. Trends Pharm Sci 24:52-55.
3. Akwa Y, Hassett DE, Eloranta ML, Sandberg K, Masliah E, Powell H, Whitton JL, Bloom FE, Campbell IL. 1998. Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration. J Immunol 161:5016-5026.
4. Amadio S, D'Ambrosi N, Cavaliere F, Murra B, Sancesario G, Bernardi G, Burnstock G, Volonté C. 2002. P2 receptor modulation and cytotoxic function in cultured CNS neurons. Neuropharmacology 42:489-501.
5. Araque A, Carmignoto G, Haydon PG. 2001. Dynamic signaling between astrocytes and neurons. Annu Rev Physiol 63:795-813.
6. Arslan G, Filipeanu CM, Irenius E, Kull B, Clementi E, Allgaier C, Erlinge D, Fredholm BB. 2000. P2Y receptors contribute to ATP-induced increases in intracellular calcium in differentiated but not undifferentiated PC12 cells. Neuropharmacology 39:482-496.
7. Barnard EA, Simon J. 2001. An elusive receptor is finally caught: P2Y(12), an important drug target in platelets. Trends Pharmacol Sci 22:388-391.
8. Bezzi P, Volterra A. 2001. A neuron-glia signaling network in the active brain. Curr Op Neurobiol 11:387-394.
9. Brambilla R, Burnstock G, Bonazzi A, Ceruti S, Cattabeni F, Abbracchio MP. 1999. Cyclo-oxygenase 2 mediates P2Y-receptor-induced reactive astrogliosis. Br J Pharmacol 126:563-567.
10. Brambilla R, Ceruti S, Malorni W, Cattabeni F, Abbracchio MP. 2000. A novel gliotic P2 receptor mediating cyclooxigenase-2 induction in rat and human astrocytes. J Auton Nerv Syst 81:3-9.
11. Brambilla R, Neary JT, Cattabeni F, Cottini L, D'ippolito GL, Schiller PE, Abbracchio MP. 2002. Induction of COX-2 and reactive gliosis by P2Y receptors in rat cortical astrocytes is dependent on ERK1/2 but independent of calcium signaling. J Neurochem 83:1285-1296.
12. Cavaliere F, Sancesario G, Bernardi G, Volonté C. 2002. Extracellular ATP and nerve growth factor intensify hypoglycemia-induced cell death in primary neurons: role of P2 and NGFRp75 receptors. J Neurochem 83:1-10.
13. Chambers, JK, Macdonald LE, Sarau HM, Ames RS, Freeman K, Foley JJ, Zhu Y, McLaughlin MM, Murdock P, McMillan L, Trill J, Swift A, Aiyar N, Taylor P, Vawter L, Naheed S, Szekeres P, Hervieu G, Scott C, Watson JM, Murphy AJ, Duzic E, Klein C, Bergsma DJ, Wilson S, Livi GP. 2000. A G protein-coupled receptor for UDP-glucose. J Biol Chem 275:10767-10771.
14. Charlton ME, Williams AS, Fogliano M, Sweetnam PM, Duman RS. 1997. The isolation and characterization of a novel G protein-coupled receptor regulated by immunologic challenge. Brain Res 764:141-148.
15. Coco S, Calegari F, Pravettoni E, Pozzi D, Taverna E, Rosa P, Matteoli M, Verderio C. 2003. Storage and release of ATP from astrocytes in culture. J Biol Chem 278:1354-1362.
16. Communi D, Gonzalez NS, Detheux M, Brezillon S, Lannoy V, Parmentier M, Boeynaems JM. 2001. Identification of a novel human ADP receptor coupled to Gi. J Biol Chem 276:41479-41485.
17. D'Ambrosi N, Cavaliere F, Merlo D, Milazzo L, Mercanti D, Volonté C. 2000. Antagonists of P2 receptor prevent NGF-dependent neuritogenesis in PC12 cells. Neuropharmacology 39:1083-1094.
18. D'Ambrosi N, Murra B, Cavaliere F, Amadio S, Bernardi G, Burnstock G, Volonté C. 2001. Interaction between ATP and nerve growth factor signalling in the survival and neuritic outgrowth from PC12 cells. Neuroscience 108:527-534.
19. Dermaut B, Kumar-Singh S, De Jonghe C, Cruts M, Lofgren A, Lubke U, Cras P, Dom R, De Deyn PP, Martin JJ, Van Broeckhoven C. 2001. Cerebral amyloid angiopathy is a pathogenic lesion in Alzheimer's disease due to a novel presenilin 1 mutation. Brain 124:2383-2392.
20. Falzoni S, Munerati M, Ferrari D, Spisani S, Moretti S, Di Virgilio F. 1995. The purinergic P2Z receptor of human macrophage cells: characterization and possible physiological role. J Clin Invest 95:1207-1216.
21. Fam SR, Gallagher CJ, Salter MW. 2000. P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes. J Neurosci 20:2800-2808.
22. Fields RD, Stevens B. 2000. ATP: an extracellular signaling molecule between neurons and glia. Trends Neurosci 23:625-633.
23. Franke H, Grosche J, Schadlich H, Krugel U, Allgaier C, Illes P. 2001. P2X receptor expression on astrocytes in the nucleus accumbens of rats. Neuroscience 108:421-429.
24. Freeman K, Tsui P, Moore D, Emson PC, Vawter L, Naheed S, Lane P, Bawagan H, Herrity N, Murphy K, Sarau HM, Ames RS, Wilson S, Livi GP, Chambers JK. 2001. Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs. Genomics 78:124-128.
25. Garzillo CL, Mello LE. 2002. Characterization of reactive astrocytes in the chronic phase of the pilocarpine model of epilepsy. Epilepsia 43(Suppl 5):107-109.
26. Guthrie PB, Knappenberg J, Segal M, Bennett MV, Charles AC, Kater SB. 1999. ATP released from astrocytes mediates glial calcium waves. J Neurosci 19:520-528.
27. Hatten ME, Liem RKH, Shelanski ML, Mason CA. 1991. Astroglia in CNS injury. Glia 4:233-243.
28. 7 receptor orthologs. J Pharmacol Exp Ther 296:947-957.
29. Ho L, Pieroni C, Winger D, Purohit DP, Aisen PS, Pasinetti GM. 1999. Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease. J Neurosci Res 57:295-303.
30. Hollopeter G, Jantzen HM, Vincent D, Li G, England L, Ramakrishnan V, Yang RB, Nurden A, Julius D, Conley PB. 2001. Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature 409:202-207.
31. Jimenez AI, E Castro, D Communi, JM Boeynaems, EG Delicado, Miras-Portugal MT. 2000. Coexpression of several types of metabotropic nucleotide receptors in single cerebellar astrocytes. J Neurochem 75:2071-2079.
32. John GR, Scemes E, Suadicani SO, Liu JSH, Charles PC, Lee SC, Spray DC, Brosnan CF. 1999. IL-β differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junctions channels. Proc Natl Acad Sci USA 96:11613-11618.
33. Khakh BS, Bao XR, Labarca C, Lester HA. 1999. Neuronal P2X trasmitter-gated cation channels change their ion selectivity in seconds. Nat Neurosci 2:322-330.
34. Khakh BS, Henderson G. 2000. Modulation of fast synaptic transmission by presynaptic ligand-gated cation channels. J Auton Nerv Syst 81:110-121.
35. Khakh BS, Burnstock G, Kennedy C, King BF, North RA, Seguela P, Voigt M, Humphrey PP. 2001. International union of pharmacology: XXIV, current status of the nomenclature and properties of P2X receptors and their subunits. Pharm Rev 53:107-118.
36. King BF, Burnstock G, Boyer JL, Boeynaems JM, Weisman GA, Kennedy C, Jacobson KA, Humphries RG, Abbracchio MP, Gachet C, Miras-Portugal MT. 2000. The P2Y receptors. In: The IUPHAR compendium of receptor characterization and classification. London: IUPHAR Media. p 307-320.
37. Koizumi S, Saito Y, Nakazawa K, Nakajima K, Sawada JI, Kohsaka S, Illes P, Inoue K. 2002. Spatial and temporal aspects of Ca(2+) signaling by P2Y receptors in cultered rat hippocampal astrocytes. Life Sci 72:431-442.
38. Kukley M, Barden JA, Steinhauser C, Jabs R. 2001. Distribution of P2X receptors on astrocytes in juvenile rat hippocampus. Glia 36:11-21.
39. Martins RN, Taddei K, Kendall C, Evin G, Bates KA, Harvey AR. 2001. Altered expression of apolipoprotein E, amyloid precursor protein and presenilin-1 is associated with chronic reactive gliosis in rat cortical tissue. Neuroscience 106:557-569.
40. 1 purinergic receptor in neurons and glial cells of the central nervous system. Brain Res Mol Brain Res 78:50-58.
41. Neary JT, Rathbone MP, Cattabeni F, Abbracchio MP, Burnstock G. 1996. Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells. Trends Neurosci 19:13-18.
42. Neary JT, Abbracchio MP. 2001. Purinergic and pyrimidinergic signalling I. In: Abbracchio MP, Williams M, editors. Handbook of experimental pharmacology, vol. 151/I. Berlin: Springer-Verlag. p 305-338.
43. Newman EA, Zahs KR. 1998. Modulation of neuronal activity by glial cells in the retina. J Neurosci 18:4022-4028.
44. 7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. J Neurosci 21:7135-7142.
45. Queiroz G, Gebicke-Haerter PJ, Schobert A, Starke K, Von Kugelgen I. 1997. Release of ATP from cultered rat astrocytes elicited by glutamate receptor activation. Neuroscience 78:1203-1208.
46. Saas P, Boucraut J, Quiquerez AL, Schnuriger V, Perrin G, Desplat-Jego S, Bernard D, Walker PR, Dietrich PH. 1999. CD95 (Fas/Apo1) as a receptor governing: astrocytes apoptotic or inflammatory responses: a key role in brain inflammation. J Immunol 162:2326-2333.
47. 2+ stores in sarcoplasmic reticulum isolated from arterial and gastric smooth muscle. Can J Physiol Pharmacol 80:588-603.
48. 7). Science 272:735-738.
49. Verderio C, Matteoli M. 2001. ATP mediates calcium signaling between astrocytes and microglial cells: modulation by IFN-γ. J Immunol 166:6383-6391.
50. Webb TE, Barnard EA. 1999. Molecular biology of P2Y receptors expressed in the nervous system. Progr Brain Res 120:23-31.
51. 2 receptors in freshly isolated astrocytes from rat hippocampus. J Neurochem 77:530-541.