Pharmacological activation of plasma-membrane K ATP channels reduces reoxygenation-induced Ca 2+ overload in cardiac myocytes via modulation of the diastolic membrane potential

British Journal of Pharmacology

Volumn 141, Issue 6, 2004, Pages 1059-1067

  Baczkó, István ^a,c   Giles, Wayne R ^a,b   Light, Peter E ^c  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

ATP sensitive potassium channels; Calcium overload; Heart; Membrane potential; Sodium calcium exchange

Indexed keywords

2 CYANO 1 (1,1 DIMETHYLPROPYL) 3 (3 PYRIDYL)GUANIDINE; ADENOSINE TRIPHOSPHATE; BARBITURIC ACID DERIVATIVE; BIS(1,3 DIBUTYLBARBITURIC ACID)TRIMETHINE OXONOL; CALCIUM ION; CLAMIKALANT; FURA 2; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DIASTOLE; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HYPERPOLARIZATION; HYPOXIA; IMAGING SYSTEM; MEMBRANE STEADY POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; REOXYGENATION;

ANIMALS; BARBITURATES; BENZAMIDES; CALCIUM; CELL HYPOXIA; CELL MEMBRANE; ELECTRIC STIMULATION; FLUORESCENT DYES; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; ISOXAZOLES; MEMBRANE POTENTIALS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PINACIDIL; POLOXAMER; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROBENECID; RATS;

EID: 1942536479     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705702     Document Type: Article

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