Effects of KATP channel openers, P-1075, pinacidil, and diazoxide, on energetics and contractile function in isolated rat hearts

Journal of Molecular and Cellular Cardiology

Volumn 34, Issue 4, 2002, Pages 427-440

  Jilkina, Olga ^a   Kuzio, Bozena ^a   Grover, Gary J ^c   Kupriyanov, Valery V ^a,b  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c BRISTOL MYERS SQUIBB   (United States)

Author keywords

2,4 dinitrophenol; 5 hydroxydecanoate; ATP sensitive K+ channels; Diazoxide; Glibenclamide; KATP opener; Oxidative phosphorylation; Oxygen consumption; P 1075; Pinacidil; Rb+ K+ efflux

Indexed keywords

2 CYANO 1 (1,1 DIMETHYLPROPYL) 3 (3 PYRIDYL)GUANIDINE; 2,4 DINITROPHENOL; ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; DECANOIC ACID DERIVATIVE; DIAZOXIDE; GLIBENCLAMIDE; PINACIDIL; POTASSIUM CHANNEL STIMULATING AGENT; RUBIDIUM ION; SODIUM 5 HYDROXYDECANOIC ACID; UNCLASSIFIED DRUG; GUANIDINE DERIVATIVE; N CYANO N' (1,1 DIMETHYLPROPYL) N'' (3 PYRIDINYL)GUANIDINE; N-CYANO-N'-(1,1-DIMETHYLPROPYL)-N''-(3-PYRIDINYL)GUANIDINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PYRIDINE DERIVATIVE; VASODILATOR AGENT;

ANIMAL TISSUE; ARTICLE; BIOENERGY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DRUG EFFECT; ENERGY METABOLISM; HEART ARREST; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MITOCHONDRION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE OXYGEN CONSUMPTION; ISOLATED HEART; MALE; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; SARCOLEMMA; ANIMAL; HEART; HEART CONTRACTION; HEART MUSCLE; IN VITRO STUDY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PERFUSION; SPRAGUE DAWLEY RAT;

2,4-DINITROPHENOL; ADENOSINE TRIPHOSPHATE; ANIMALS; DIAZOXIDE; GUANIDINES; HEART; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MYOCARDIAL CONTRACTION; MYOCARDIUM; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PERFUSION; PHOSPHOCREATINE; PINACIDIL; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; VASODILATOR AGENTS;

EID: 0036549813     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2001.1524     Document Type: Article

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