Role of the reverse mode of the Na+/Ca2+ exchanger in reoxygenation-induced cardiomyocyte injury

Cardiovascular Research

Volumn 51, Issue 2, 2001, Pages 241-250

  Schafer C ^a   Ladilov, Y ^a   Inserte, J ^b   Schafer M ^a   Haffner, S ^a   Garcia Dorado, D ^b   Piper, H M ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b HOSPITAL GENERAL DE CATALUNYA   (Spain)

Author keywords

Calcium (cellular); Ischemia; Myocytes; Na Ca exchanger; Reperfusion

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; CALCIUM ION; SODIUM ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL ISOLATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME RELEASE; EXTRACELLULAR CALCIUM; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART VENTRICLE HYPERTROPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REOXYGENATION; REPERFUSION INJURY; SODIUM CALCIUM EXCHANGE;

ANALYSIS OF VARIANCE; ANIMALS; CALCIUM; CELL SIZE; CELLS, CULTURED; CYTOSOL; HYDROGEN-ION CONCENTRATION; MALE; MODELS, ANIMAL; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SODIUM; SODIUM-CALCIUM EXCHANGER; THIOUREA; TIME FACTORS;

EID: 0034934941     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(01)00282-6     Document Type: Article

References (28)

1. Direct observation of the 'oxygen paradox' in single rat ventricular myocytes
2. Contracture of isolated rat heart cells on anaerobic to aerobic transition
3. Sarcolemmal integrity and metabolic competence of cardiomyocytes under anoxia-reoxygenation
4. Myocardial segment shrinkage during coronary reperfusion in situ
5. Contraction band necrosis and irreversible myocardial injury
6. Halothane protects cardiomyocytes against reoxygenation-induced hypercontracture
7. + exchange
8. 2+-exchanger via protein kinase C
9. 2+-exchange current in guinea-pig cardiac ventricular cells
10. 2+ exchanger
11. 2+ exchange, KB-R 7943, on reoxygenation-induced injuries in guinea pig papillary muscles
12. Culturing of calcium stable adult cardiac myocytes
13. Cytosolic free calcium in single rat heart cells during anoxia and reoxygenation
14. Protection of energy status of hypoxic cardiomyocytes by mild acidosis
15. Quantitation of intracellular free calcium in single adult cardiomyocytes by fura-2 fluorescence microscopy: Calibration of fura-2 ratios
16. 2+ indicators with greatly improved fluorescence properties
17. Simulated ischemia increases the susceptibility of rat cardiomyocytes to hypercontracture
18. Importance of sodium for recovery of calcium control in reoxygenated cardiomyocytes
19. Protection of rat cardiomyocytes against simulated ischemia and reoxygenation by treatment with protein kinase C activator
20. Sodium channel blockade reduces sodium loading and sodium-dependent calcium loading
21. Amiloride delays the ischemia-induced rise in cytosolic free calcium
22. 2+ overload and impairs function in anoxic rat hearts
23. 2+ exchange and not by its antioxidant effects
24. Inhibition of sodium and calcium overload pathology in the myocardium: A new cytoprotective principle
25. 2+-overload
26. Regional contractile blockade at the onset of reperfusion reduces infarct size in the dog heart
27. Prevention of the oxygen paradox in hypoxic-reoxygenated hearts
28. Effect of halothane on myocardial reoxygenation injury in isolated rat heart