Recent developments in the optimization of thermostable DNA polymerases for efficient applications

Trends in Biotechnology

Volumn 22, Issue 5, 2004, Pages 253-260

  Pavlov, Andrey R ^a   Pavlova, Nadejda V ^a   Kozyavkin, Sergei A ^a   Slesarev, Alexei I ^a  

^a Fidelity Systems Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENZYMES; GENETIC ENGINEERING; OPTIMIZATION;

CHAIN REACTIONS; NATURAL COUNTERPARTS;

BIOTECHNOLOGY;

DNA; DNA POLYMERASE;

DNA; POLYMER;

ACCURACY; BIOTECHNOLOGY; CATALYSIS; CHIMERA; DNA SEQUENCE; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME STRUCTURE; GENE AMPLIFICATION; GENE MUTATION; GENETIC SCREENING; GENOME ANALYSIS; HUMAN; HUMAN GENOME; MOLECULAR CLONING; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROCESSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STANDARD; STRUCTURE ANALYSIS; TEMPERATURE; THERMOSTABILITY;

ARCHAEA; ARCHAEAL PROTEINS; BACTERIA; BACTERIAL PROTEINS; DEOXYRIBONUCLEOTIDES; DNA POLYMERASE I; DNA PRIMERS; DNA-DIRECTED RNA POLYMERASES; ENZYME STABILITY; HEAT; KINETICS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; VIRAL PROTEINS;

EID: 1942534174     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibtech.2004.02.011     Document Type: Review

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