-
1
-
-
0036591874
-
Structural biology in drug design: Selective protein kinase inhibitors
-
Scapin G: Structural biology in drug design: selective protein kinase inhibitors. Drug Discov Today 2002;7:601-611.
-
(2002)
Drug Discov Today
, vol.7
, pp. 601-611
-
-
Scapin, G.1
-
3
-
-
0035413612
-
Histidine phosphorylation and two-component signaling in eukaryotic cells
-
Saito H: Histidine phosphorylation and two-component signaling in eukaryotic cells. Chem Rev 2001;101:2497-2510.
-
(2001)
Chem Rev
, vol.101
, pp. 2497-2510
-
-
Saito, H.1
-
4
-
-
0026793456
-
Growth factor signaling by receptor tyrosine kinases
-
Schlessinger J, Ullrich A: Growth factor signaling by receptor tyrosine kinases. Neuron 1992;9:383-391.
-
(1992)
Neuron
, vol.9
, pp. 383-391
-
-
Schlessinger, J.1
Ullrich, A.2
-
5
-
-
0030953448
-
Protein tyrosine phosphatases in signal transduction
-
Neel BG, Tonks NK: Protein tyrosine phosphatases in signal transduction. Curr Opin Cell Biol 1997;9:193-204.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 193-204
-
-
Neel, B.G.1
Tonks, N.K.2
-
6
-
-
0035413605
-
Protein phosphatases - A phylogenetic perspective
-
Kennelly PJ: Protein phosphatases - a phylogenetic perspective. Chem Rev 2001;101:2291-2312.
-
(2001)
Chem Rev
, vol.101
, pp. 2291-2312
-
-
Kennelly, P.J.1
-
7
-
-
0035413604
-
Molecular reactions of protein phosphatases - Insights from structure and chemistry
-
Jackson MD, Denu JM: Molecular reactions of protein phosphatases - insights from structure and chemistry. Chem Rev 2001;101:2313-2340.
-
(2001)
Chem Rev
, vol.101
, pp. 2313-2340
-
-
Jackson, M.D.1
Denu, J.M.2
-
8
-
-
0034256094
-
Inhibition of tumor angiogenesis by synthetic receptor tyrosine kinase inhibitors
-
Sun L, McMahon G: Inhibition of tumor angiogenesis by synthetic receptor tyrosine kinase inhibitors. Drug Discov Today 2000;5:344-353.
-
(2000)
Drug Discov Today
, vol.5
, pp. 344-353
-
-
Sun, L.1
McMahon, G.2
-
9
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G, Goeddel DV: TNF-R1 signaling: a beautiful pathway. Science 2002;296:1634-1635.
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
10
-
-
0036677887
-
Therapeutic modulation of inflammatory gene transcription by kinase inhibitors
-
Alton G, Schwamborn K, Satoh Y, Westwick JK: Therapeutic modulation of inflammatory gene transcription by kinase inhibitors. Expert Opin Biol Ther 2002;2:621-632.
-
(2002)
Expert Opin Biol Ther
, vol.2
, pp. 621-632
-
-
Alton, G.1
Schwamborn, K.2
Satoh, Y.3
Westwick, J.K.4
-
11
-
-
0036358166
-
TGF-beta: Receptors, signaling pathways and autoimmunity
-
Chen W, Wahl SM: TGF-beta: receptors, signaling pathways and autoimmunity. Curr Dir Autoimmun 2002;5:62-91.
-
(2002)
Curr Dir Autoimmun
, vol.5
, pp. 62-91
-
-
Chen, W.1
Wahl, S.M.2
-
12
-
-
0034468138
-
Janus kinases and signal transducers and activators of transcription: Their roles in cytokine signaling, development and immunoregulation
-
Ortmann RA, Cheng T, Visconti R, Frucht DM, O' Shea JJ: Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation. Arthritis Res 2000;2:16-32.
-
(2000)
Arthritis Res
, vol.2
, pp. 16-32
-
-
Ortmann, R.A.1
Cheng, T.2
Visconti, R.3
Frucht, D.M.4
O'Shea, J.J.5
-
13
-
-
0037106332
-
A non-radioactive method for the assay of many serine/threonine-s kinases
-
Ross H, Armstrong CG, Cohen P: A non-radioactive method for the assay of many serine/threonine-s kinases. Biochem J 2002;366:977-981.
-
(2002)
Biochem J
, vol.366
, pp. 977-981
-
-
Ross, H.1
Armstrong, C.G.2
Cohen, P.3
-
14
-
-
0032518347
-
A fluorescence polarization competition immunoassay for tyrosine kinases
-
Seethala R, Menzel R: A fluorescence polarization competition immunoassay for tyrosine kinases. Anal Biochem 1998;255:257-262.
-
(1998)
Anal Biochem
, vol.255
, pp. 257-262
-
-
Seethala, R.1
Menzel, R.2
-
15
-
-
0008190079
-
Development of high throughput screening assays using fluorescence polarization: Nuclear receptor-ligand-binding and kinase/phosphatase assays
-
Parker GJ, Law TL, Lenoch FJ, Bolger RE: Development of high throughput screening assays using fluorescence polarization: nuclear receptor-ligand- binding and kinase/phosphatase assays. J Biomol Screen 2000;5:77-88.
-
(2000)
J Biomol Screen
, vol.5
, pp. 77-88
-
-
Parker, G.J.1
Law, T.L.2
Lenoch, F.J.3
Bolger, R.E.4
-
16
-
-
0035991330
-
Comparison of assay technologies for a tyrosine kinase assay generates different results in high throughput screening
-
Sills MA, Weiss D, Pham Q, Schweitzer R, Wu X, Wu JJ: Comparison of assay technologies for a tyrosine kinase assay generates different results in high throughput screening. J Biomol Screen 2002;7:191-214.
-
(2002)
J Biomol Screen
, vol.7
, pp. 191-214
-
-
Sills, M.A.1
Weiss, D.2
Pham, Q.3
Schweitzer, R.4
Wu, X.5
Wu, J.J.6
-
17
-
-
0034872407
-
A cGMP-dependent protein kinase assay for high throughput screening based on time-resolved fluorescence resonance energy transfer
-
Bader B, Butt E, Palmetshofer A, Walter U, Jarchau T, Drueckes P: A cGMP-dependent protein kinase assay for high throughput screening based on time-resolved fluorescence resonance energy transfer. J Biomol Screen 2001;6:255-264.
-
(2001)
J Biomol Screen
, vol.6
, pp. 255-264
-
-
Bader, B.1
Butt, E.2
Palmetshofer, A.3
Walter, U.4
Jarchau, T.5
Drueckes, P.6
-
18
-
-
0033541662
-
Homogeneous proximity tyrosine kinase assays: Scintillation proximity assay versus homogeneous time-resolved fluorescence
-
Park YW, Cummings RT, Wu L, Zheng S, Cameron PM, Woods A, et al: Homogeneous proximity tyrosine kinase assays: scintillation proximity assay versus homogeneous time-resolved fluorescence. Anal Biochem 1999;269:94-104.
-
(1999)
Anal Biochem
, vol.269
, pp. 94-104
-
-
Park, Y.W.1
Cummings, R.T.2
Wu, L.3
Zheng, S.4
Cameron, P.M.5
Woods, A.6
-
19
-
-
0030201076
-
Measurement of the protein tyrosine kinase activity of c-src using time-resolved fluorometry of europium chelates
-
Braunwalder AF, Yarwood DR, Sills MA, Lipson KE: Measurement of the protein tyrosine kinase activity of c-src using time-resolved fluorometry of europium chelates. Anal Biochem 1996;238:159-164.
-
(1996)
Anal Biochem
, vol.238
, pp. 159-164
-
-
Braunwalder, A.F.1
Yarwood, D.R.2
Sills, M.A.3
Lipson, K.E.4
-
21
-
-
0033822413
-
Detection of p56(lck) kinase activity using scintillation proximity assay in 384-well format and imaging proximity assay in 384- and 1536-well format
-
Beveridge M, Park YW, Hermes J, Marenghi A, Brophy G, Santos A: Detection of p56(lck) kinase activity using scintillation proximity assay in 384-well format and imaging proximity assay in 384- and 1536-well format. J Biomol Screen 2000;5:205-212.
-
(2000)
J Biomol Screen
, vol.5
, pp. 205-212
-
-
Beveridge, M.1
Park, Y.W.2
Hermes, J.3
Marenghi, A.4
Brophy, G.5
Santos, A.6
-
22
-
-
0344177511
-
A scintillation proximity assay for the Raf/MEK/ERK kinase cascade: High-throughput screening and identification of selective enzyme inhibitors
-
McDonald OB, Chen WJ, Ellis B, Hoffman C, Overton L, Rink M, et al: A scintillation proximity assay for the Raf/MEK/ERK kinase cascade: high-throughput screening and identification of selective enzyme inhibitors. Anal Biochem 1999;268:318-329.
-
(1999)
Anal Biochem
, vol.268
, pp. 318-329
-
-
McDonald, O.B.1
Chen, W.J.2
Ellis, B.3
Hoffman, C.4
Overton, L.5
Rink, M.6
-
23
-
-
0037016352
-
A scintillation proximity assay for studying inhibitors of human tau protein kinase II/cdk5 using a 96-well format
-
Evans DB, Rank KB, Sharma SK: A scintillation proximity assay for studying inhibitors of human tau protein kinase II/cdk5 using a 96-well format. J Biochem Biophys Methods 2002;50:151-161.
-
(2002)
J Biochem Biophys Methods
, vol.50
, pp. 151-161
-
-
Evans, D.B.1
Rank, K.B.2
Sharma, S.K.3
-
24
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
Zhang JH, Chung TD, Oldenburg KR: A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 1999;4:67-73.
-
(1999)
J Biomol Screen
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
25
-
-
0024353865
-
Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein
-
Glass DB, Cheng HC, Mende-Mueller L, Reed J, Walsh DA: Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein. J Biol Chem 1989;264:8802-8810.
-
(1989)
J Biol Chem
, vol.264
, pp. 8802-8810
-
-
Glass, D.B.1
Cheng, H.C.2
Mende-Mueller, L.3
Reed, J.4
Walsh, D.A.5
-
26
-
-
0024401290
-
Protein kinase inhibitor-(6-22)-amide peptide analogs with standard and nonstandard amino acid substitutions for phenylalanine 10: Inhibition of cAMP-dependent protein kinase
-
Glass DB, Lundquist LJ, Katz BM, Walsh DA: Protein kinase inhibitor-(6-22)-amide peptide analogs with standard and nonstandard amino acid substitutions for phenylalanine 10: inhibition of cAMP-dependent protein kinase. J Biol Chem 1989;264:14579-14584.
-
(1989)
J Biol Chem
, vol.264
, pp. 14579-14584
-
-
Glass, D.B.1
Lundquist, L.J.2
Katz, B.M.3
Walsh, D.A.4
|