Structure-activity comparison of YZ-069, a novel σ ligand, and four analogs in receptor binding and behavioral studies

Pharmacology Biochemistry and Behavior

Volumn 77, Issue 4, 2004, Pages 775-781

  Matsumoto, Rae R ^a   Potelleret, Florence Hourcade ^a   MacK, Aisha ^a   Pouw, Buddy ^a   Zhang, Ying ^b   Bowen, Wayne D ^b  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Receptor; Cocaine; Convulsions

Indexed keywords

COCAINE; LIGAND; MONOAMINE; N PHENYLPROPYL N' (3,4 DICHLOROPHENETHYL)PIPERAZINE; PHENYL GROUP; PIPERAZINE DERIVATIVE; PROTEIN SUBUNIT; RECEPTOR; UNCLASSIFIED DRUG; YZ 069;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; CONTROLLED STUDY; CONVULSION; DRUG STRUCTURE; EVALUATION; LIPOPHILICITY; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

ANIMALS; COCAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; LIGANDS; MALE; MICE; PIPERAZINES; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SIGMA; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1942487797     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2004.01.014     Document Type: Article

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