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Volumn 472, Issue 4, 2004, Pages 496-511

The 5-HT2A Receptor Is Widely Distributed in the Rat Spinal Cord and Mainly Localized at the Plasma Membrane of Postsynaptic Neurons

Author keywords

Dorsal horn; Locomotion; Nociception; Serotonin; Ultrastructure

Indexed keywords

CHOLINE ACETYLTRANSFERASE; SEROTONIN 2A RECEPTOR;

EID: 1942484879     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/cne.20082     Document Type: Article
Times cited : (91)

References (74)
  • 1
    • 0025973165 scopus 로고
    • Antinociceptive effect of ketanserin in mice: Involvement of supraspinal 5-HT2 receptors in nociceptive transmission
    • Alhaider AA. 1991. Antinociceptive effect of ketanserin in mice: involvement of supraspinal 5-HT2 receptors in nociceptive transmission. Brain Res 543:335-340.
    • (1991) Brain Res , vol.543 , pp. 335-340
    • Alhaider, A.A.1
  • 2
    • 0027413319 scopus 로고
    • Ultrastructural morphology, synaptic relationships, and CGRP immunoreactivity of physiologically identified C-fiber terminals in the monkey spinal cord
    • Alvarez FJ, Kavookjian AM, Light AR. 1993. Ultrastructural morphology, synaptic relationships, and CGRP immunoreactivity of physiologically identified C-fiber terminals in the monkey spinal cord. J Comp Neurol 329:472-490.
    • (1993) J Comp Neurol , vol.329 , pp. 472-490
    • Alvarez, F.J.1    Kavookjian, A.M.2    Light, A.R.3
  • 3
    • 0032579782 scopus 로고    scopus 로고
    • Distribution of 5-hydroxytryptamine-immunoreactive boutons on alpha-motoneurons in the lumbar spinal cord of adult cats
    • Alvarez FJ, Pearson JC, Harrington D, Dewey D, Torbeck L, Fyffe RE. 1998. Distribution of 5-hydroxytryptamine-immunoreactive boutons on alpha-motoneurons in the lumbar spinal cord of adult cats. J Comp Neurol 393:69-83.
    • (1998) J Comp Neurol , vol.393 , pp. 69-83
    • Alvarez, F.J.1    Pearson, J.C.2    Harrington, D.3    Dewey, D.4    Torbeck, L.5    Fyffe, R.E.6
  • 4
    • 0036460098 scopus 로고    scopus 로고
    • Locomotor recovery in the chronic spinal rat: Effects of long-term treatment with a 5-HT2 agonist
    • Antri M, Orsal D, Barthe JY. 2002. Locomotor recovery in the chronic spinal rat: effects of long-term treatment with a 5-HT2 agonist. Eur J Neurosci 16:467-476.
    • (2002) Eur J Neurosci , vol.16 , pp. 467-476
    • Antri, M.1    Orsal, D.2    Barthe, J.Y.3
  • 6
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-HT receptors and their function
    • Barnes NM, Sharp T. 1999. A review of central 5-HT receptors and their function. Neuropharmacology 38:1083-1152.
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 7
    • 0034988115 scopus 로고    scopus 로고
    • Distribution of serotonin 2A and 2C receptor mRNA expression in the cervical ventral horn and phrenic motoneurons following spinal cord hemisection
    • Basura GJ, Zhou SY, Walker PD, Goshgarian HG. 2001. Distribution of serotonin 2A and 2C receptor mRNA expression in the cervical ventral horn and phrenic motoneurons following spinal cord hemisection. Exp Neurol 169:255-263.
    • (2001) Exp Neurol , vol.169 , pp. 255-263
    • Basura, G.J.1    Zhou, S.Y.2    Walker, P.D.3    Goshgarian, H.G.4
  • 8
    • 0019837585 scopus 로고
    • Origins of serotonergic projections to the spinal cord in rat: An immunocytochemical-retrograde transport study
    • Bowker RM, Westlund KN, Coulter JD. 1981. Origins of serotonergic projections to the spinal cord in rat: an immunocytochemical-retrograde transport study. Brain Res 226:187-199.
    • (1981) Brain Res , vol.226 , pp. 187-199
    • Bowker, R.M.1    Westlund, K.N.2    Coulter, J.D.3
  • 9
    • 0032441876 scopus 로고    scopus 로고
    • Functional chemical neuroanatomy of serotonergic neurons and their targets: Antibody production and immunohistochemistry (IHC) for 5-HT, its precursor (5-HTP) and metabolite (5-HIAA), biosynthetic enzyme (TPH), transporter (SERT) and three receptors (5-HT2A, 5-HT5A, 5-HT7)
    • Brownfield MS, Yracheta J, Chu F, Lorenz D, Diaz A. 1998. Functional chemical neuroanatomy of serotonergic neurons and their targets: antibody production and immunohistochemistry (IHC) for 5-HT, its precursor (5-HTP) and metabolite (5-HIAA), biosynthetic enzyme (TPH), transporter (SERT) and three receptors (5-HT2A, 5-HT5A, 5-HT7). Ann NY Acad Sci 861:232-233.
    • (1998) Ann NY Acad Sci , vol.861 , pp. 232-233
    • Brownfield, M.S.1    Yracheta, J.2    Chu, F.3    Lorenz, D.4    Diaz, A.5
  • 10
    • 0030790011 scopus 로고    scopus 로고
    • Immunohistochemical localization of 5-HT2A receptors in peripheral sensory axons in rat glabrous skin
    • Carlton SM, Coggeshall RE. 1997. Immunohistochemical localization of 5-HT2A receptors in peripheral sensory axons in rat glabrous skin. Brain Res 763:271-275.
    • (1997) Brain Res , vol.763 , pp. 271-275
    • Carlton, S.M.1    Coggeshall, R.E.2
  • 11
    • 0033608780 scopus 로고    scopus 로고
    • Distribution of 5-hydroxytryptamine-immunoreactive boutons on immunohistochemically-identified Renshaw cells in cat and rat lumbar spinal cord
    • Carr PA, Pearson JC, Fyffe RE. 1999. Distribution of 5-hydroxytryptamine-immunoreactive boutons on immunohistochemically-identified Renshaw cells in cat and rat lumbar spinal cord. Brain Res 823:198-201.
    • (1999) Brain Res , vol.823 , pp. 198-201
    • Carr, P.A.1    Pearson, J.C.2    Fyffe, R.E.3
  • 13
    • 0029027070 scopus 로고
    • Ultrastructural immunolabeling shows prominent presynaptic vesicular localization of delta-opioid receptor within both enkephalin- and nonenkephalin-containing axon terminals in the superficial layers of the rat cervical spinal cord
    • Cheng PY, Svingos AL, Wang H, Clarke CL, Jenab S, Beczkowska IW, Inturrisi CE, Pickel VM. 1995. Ultrastructural immunolabeling shows prominent presynaptic vesicular localization of delta-opioid receptor within both enkephalin- and nonenkephalin-containing axon terminals in the superficial layers of the rat cervical spinal cord. J Neurosci 15:5976-5988.
    • (1995) J Neurosci , vol.15 , pp. 5976-5988
    • Cheng, P.Y.1    Svingos, A.L.2    Wang, H.3    Clarke, C.L.4    Jenab, S.5    Beczkowska, I.W.6    Inturrisi, C.E.7    Pickel, V.M.8
  • 14
    • 0033612553 scopus 로고    scopus 로고
    • Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat
    • Cornea-Hebert V, Riad M, Wu C, Singh SK, Descarries L. 1999. Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat. J Comp Neurol 409:187-209.
    • (1999) J Comp Neurol , vol.409 , pp. 187-209
    • Cornea-Hebert, V.1    Riad, M.2    Wu, C.3    Singh, S.K.4    Descarries, L.5
  • 15
    • 0037008452 scopus 로고    scopus 로고
    • Similar ultrastructural distribution of the 5-HT(2A) serotonin receptor and microtubule-associated protein MAP1A in cortical dendrites of adult rat
    • Cornea-Hebert V, Watkins KC, Roth BL, Kroeze WK, Gaudreau P, Leclerc N, Descarries L. 2002. Similar ultrastructural distribution of the 5-HT(2A) serotonin receptor and microtubule-associated protein MAP1A in cortical dendrites of adult rat. Neuroscience 113:23-35.
    • (2002) Neuroscience , vol.113 , pp. 23-35
    • Cornea-Hebert, V.1    Watkins, K.C.2    Roth, B.L.3    Kroeze, W.K.4    Gaudreau, P.5    Leclerc, N.6    Descarries, L.7
  • 16
    • 0023616923 scopus 로고
    • Monoclonal antibodies to substance P: Production, characterization of their fine specificities, and use in immunocytochemistry
    • Couraud JY, Frobert Y, Conrath M, Renzi D, Grassi J, Drapeau G, Regoli D, Pradelles P. 1987. Monoclonal antibodies to substance P: production, characterization of their fine specificities, and use in immunocytochemistry. J Neurochem 49:1708-1719.
    • (1987) J Neurochem , vol.49 , pp. 1708-1719
    • Couraud, J.Y.1    Frobert, Y.2    Conrath, M.3    Renzi, D.4    Grassi, J.5    Drapeau, G.6    Regoli, D.7    Pradelles, P.8
  • 17
    • 0032211322 scopus 로고    scopus 로고
    • NK1, NMDA, 5HT1a, and 5HT2 receptor binding sites in the rat lumbar spinal cord: Modulation following sciatic nerve crush
    • Croul S, Radzievsky A, Sverstiuk A, Murray M. 1998. NK1, NMDA, 5HT1a, and 5HT2 receptor binding sites in the rat lumbar spinal cord: modulation following sciatic nerve crush. Exp Neurol 154:66-79.
    • (1998) Exp Neurol , vol.154 , pp. 66-79
    • Croul, S.1    Radzievsky, A.2    Sverstiuk, A.3    Murray, M.4
  • 18
    • 0026062468 scopus 로고
    • Fine structure and synaptic architecture of HRP-labelled primary afferent termination in lamina IIi of the rat dorsal horn
    • Cruz F, Lima D, Zieglgansberger W, Coimbra A. 1991. Fine structure and synaptic architecture of HRP-labelled primary afferent termination in lamina IIi of the rat dorsal horn. J Comp Neurol 305:3-16.
    • (1991) J Comp Neurol , vol.305 , pp. 3-16
    • Cruz, F.1    Lima, D.2    Zieglgansberger, W.3    Coimbra, A.4
  • 19
    • 0001989283 scopus 로고
    • Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brainstem neurons
    • Dahlstrom A, Fuxe K. 1964. Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brainstem neurons. Acta Physiol Scand Suppl 232:1-55.
    • (1964) Acta Physiol Scand Suppl , vol.232 , pp. 1-55
    • Dahlstrom, A.1    Fuxe, K.2
  • 20
    • 0026560795 scopus 로고
    • Serotonin and L-norepinephrine as mediators of altered excitability in neonatal rat motoneurons studied in vitro
    • Elliott P, Wallis DI. 1992. Serotonin and L-norepinephrine as mediators of altered excitability in neonatal rat motoneurons studied in vitro. Neuroscience 47:533-544.
    • (1992) Neuroscience , vol.47 , pp. 533-544
    • Elliott, P.1    Wallis, D.I.2
  • 22
    • 0023630323 scopus 로고
    • Effects of 5,7-dihydroxytryptamine on serotoninl and serotonin2 receptors throughout the rat central nervous system using quantitative autoradiography
    • Fischette CT, Nock B, Renner K. 1987. Effects of 5,7-dihydroxytryptamine on serotoninl and serotonin2 receptors throughout the rat central nervous system using quantitative autoradiography. Brain Res 421:263-279.
    • (1987) Brain Res , vol.421 , pp. 263-279
    • Fischette, C.T.1    Nock, B.2    Renner, K.3
  • 23
    • 0035906257 scopus 로고    scopus 로고
    • Distribution of serotonin 2A, 2C and 3 receptor mRNA in spinal cord and medulla oblongata
    • Fonseca MI, Ni YG, Dunning DD, Miledi R. 2001. Distribution of serotonin 2A, 2C and 3 receptor mRNA in spinal cord and medulla oblongata. Brain Res Mol Brain Res 89:11-19.
    • (2001) Brain Res Mol Brain Res , vol.89 , pp. 11-19
    • Fonseca, M.I.1    Ni, Y.G.2    Dunning, D.D.3    Miledi, R.4
  • 24
    • 0025908176 scopus 로고    scopus 로고
    • Analgesic profile of centrally administered 2-methyl-serotonin against acute pain in rats
    • Giordanno J. 2001. Analgesic profile of centrally administered 2-methyl-serotonin against acute pain in rats. Eur J Pharmacol 199:233-236.
    • (2001) Eur J Pharmacol , vol.199 , pp. 233-236
    • Giordanno, J.1
  • 25
    • 0034283252 scopus 로고    scopus 로고
    • Coupling between serotoninergic and noradrenergic neurones and gamma-motoneurones in the cat
    • Gladden MH, Maxwell DJ, Sahal A, Jankowska E. 2000. Coupling between serotoninergic and noradrenergic neurones and gamma-motoneurones in the cat. J Physiol 527:213-223.
    • (2000) J Physiol , vol.527 , pp. 213-223
    • Gladden, M.H.1    Maxwell, D.J.2    Sahal, A.3    Jankowska, E.4
  • 26
    • 0024253655 scopus 로고
    • A study of 5-HT-receptors associated with afferent nerves located in normal and inflamed rat ankle joints
    • Grubb BD, McQueen DS, Iggo A, Birrell GJ, Dutia MB. 1988. A study of 5-HT-receptors associated with afferent nerves located in normal and inflamed rat ankle joints. Agents Actions 25:216-218.
    • (1988) Agents Actions , vol.25 , pp. 216-218
    • Grubb, B.D.1    McQueen, D.S.2    Iggo, A.3    Birrell, G.J.4    Dutia, M.B.5
  • 27
    • 0003002165 scopus 로고    scopus 로고
    • Serotonin and its receptors in pain control
    • Sawynok J and Cowan A, editors. New York: Wiley
    • Hamon M, Bourgoin S. 1999. Serotonin and its receptors in pain control. In: Sawynok J and Cowan A, editors: Novel aspects of pain management: opioids and beyond. New York: Wiley. p 203-228.
    • (1999) Novel Aspects of Pain Management: Opioids and Beyond , pp. 203-228
    • Hamon, M.1    Bourgoin, S.2
  • 28
    • 0026357503 scopus 로고
    • 5-Hydroxytryptamine1C/2 agonists in the thoracic spinal cord: Cardiovascular effects and binding sites in the intermediolateral cell column
    • Helke CJ, Thor KB, Phillips ET. 1991. 5-Hydroxytryptamine1C/2 agonists in the thoracic spinal cord: cardiovascular effects and binding sites in the intermediolateral cell column. J Pharmacol Exp Ther 259:1335-1343.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 1335-1343
    • Helke, C.J.1    Thor, K.B.2    Phillips, E.T.3
  • 29
    • 0028670366 scopus 로고
    • 5-Hydroxytryptamine2A, 5-hydroxytryptamine2B, and 5-hydroxytryptamine2C receptor mRNA expression in the spinal cord of rat, cat, monkey and human
    • Helton LA, Thor KB, Baez M. 1994. 5-hydroxytryptamine2A, 5-hydroxytryptamine2B, and 5-hydroxytryptamine2C receptor mRNA expression in the spinal cord of rat, cat, monkey and human. Neuroreport 20:2617-2620.
    • (1994) Neuroreport , vol.20 , pp. 2617-2620
    • Helton, L.A.1    Thor, K.B.2    Baez, M.3
  • 30
    • 0020570688 scopus 로고
    • Immunocytochemical identification of serotonin axonal contacts on characterized neurons in laminae I and II of the cat dorsal horn
    • Hoffert MJ, Miletic V, Ruda MA, Dubner R. 1983. Immunocytochemical identification of serotonin axonal contacts on characterized neurons in laminae I and II of the cat dorsal horn. Brain Res 267:361-364.
    • (1983) Brain Res , vol.267 , pp. 361-364
    • Hoffert, M.J.1    Miletic, V.2    Ruda, M.A.3    Dubner, R.4
  • 31
    • 0023243498 scopus 로고
    • Spinal location of the motoneurons innervating the abdominal cutaneous maximus latissimus dorsi and longissimus dorsi muscles in the cat
    • Holstege G, Van Neerven J, Evertse F, 1987. Spinal location of the motoneurons innervating the abdominal cutaneous maximus latissimus dorsi and longissimus dorsi muscles in the cat. Exp Brain Res 67:179-194.
    • (1987) Exp Brain Res , vol.67 , pp. 179-194
    • Holstege, G.1    Van Neerven, J.2    Evertse, F.3
  • 32
    • 0028331679 scopus 로고
    • Role of serotonin and catecholamines in sympathetic responses evoked by stimulation of rostral medulla
    • Huangfu D, Hwang LJ, Riley TA, Guyenet PG. 1994. Role of serotonin and catecholamines in sympathetic responses evoked by stimulation of rostral medulla. Am J Physiol 266:338-352.
    • (1994) Am J Physiol , vol.266 , pp. 338-352
    • Huangfu, D.1    Hwang, L.J.2    Riley, T.A.3    Guyenet, P.G.4
  • 33
    • 0022527005 scopus 로고
    • Serotonin innervation of physiologically identified lamina I projection neurons
    • Hylden JL, Hayashi H, Ruda MA, Dubner R. 1986. Serotonin innervation of physiologically identified lamina I projection neurons. Brain Res 370:401-404.
    • (1986) Brain Res , vol.370 , pp. 401-404
    • Hylden, J.L.1    Hayashi, H.2    Ruda, M.A.3    Dubner, R.4
  • 34
    • 0031594813 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites
    • Jakab RL, Goldman-Rakic PS. 1998. 5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites. Proc Natl Acad Sci USA 95:735-740.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 735-740
    • Jakab, R.L.1    Goldman-Rakic, P.S.2
  • 35
    • 0030931826 scopus 로고    scopus 로고
    • A confocal and electron microscopic study of contacts between 5-HT fibers and feline dorsal horn interneurons in pathways from muscle afferents
    • Jankowska E, Maxwell DJ, Dolk S, Dahlstrom A. 1997. A confocal and electron microscopic study of contacts between 5-HT fibers and feline dorsal horn interneurons in pathways from muscle afferents. J Comp Neurol 387:430-438.
    • (1997) J Comp Neurol , vol.387 , pp. 430-438
    • Jankowska, E.1    Maxwell, D.J.2    Dolk, S.3    Dahlstrom, A.4
  • 36
    • 0037201146 scopus 로고    scopus 로고
    • Serotonin potentiation of glycine-activated whole-cell currents in the superficial laminae neurons of the rat spinal dorsal horn is mediated by protein kinase C
    • Li H, Kang JF, Li YQ. 2002. Serotonin potentiation of glycine-activated whole-cell currents in the superficial laminae neurons of the rat spinal dorsal horn is mediated by protein kinase C. Brain Res Bull 58:593-600.
    • (2002) Brain Res Bull , vol.58 , pp. 593-600
    • Li, H.1    Kang, J.F.2    Li, Y.Q.3
  • 37
    • 0031008960 scopus 로고    scopus 로고
    • Association of serotonin-like immunoreactive axons with nociceptive projection neurons in the caudal spinal trigeminal nucleus of the rat
    • Li JL, Kaneko T, Nomura S, Li YQ, Mizuno N. 1997. Association of serotonin-like immunoreactive axons with nociceptive projection neurons in the caudal spinal trigeminal nucleus of the rat. J Comp Neurol 384:127-141.
    • (1997) J Comp Neurol , vol.384 , pp. 127-141
    • Li, J.L.1    Kaneko, T.2    Nomura, S.3    Li, Y.Q.4    Mizuno, N.5
  • 38
    • 0032557923 scopus 로고    scopus 로고
    • The cellular localization of 5-HT2A receptors in the spinal cord and spinal ganglia of the adult rat
    • Maeshima T, Ito R, Hamada S, Senzaki K, Hamaguchi-Hamada K, Shutoh F, Okado N. 1998. The cellular localization of 5-HT2A receptors in the spinal cord and spinal ganglia of the adult rat. Brain Res 797:118-124.
    • (1998) Brain Res , vol.797 , pp. 118-124
    • Maeshima, T.1    Ito, R.2    Hamada, S.3    Senzaki, K.4    Hamaguchi-Hamada, K.5    Shutoh, F.6    Okado, N.7
  • 39
    • 0026101260 scopus 로고
    • Serotonergic innervation of the dorsal horn of rat spinal cord: Light and electron microscopic immunocytochemical study
    • Marlier L, Sandillon F, Poulat P, Rajaofetra N, Geffard M, Privat A. 1991a. Serotonergic innervation of the dorsal horn of rat spinal cord: light and electron microscopic immunocytochemical study. J Neurocytol 20:310-322.
    • (1991) J Neurocytol , vol.20 , pp. 310-322
    • Marlier, L.1    Sandillon, F.2    Poulat, P.3    Rajaofetra, N.4    Geffard, M.5    Privat, A.6
  • 40
    • 0025782221 scopus 로고
    • Autoradiographic mapping of 5-HT1, 5-HT1A, 5-HT1B and 5-HT2 receptors in the rat spinal cord
    • Marlier L, Teilhac JR, Cerruti C, Privat A. 1991b. Autoradiographic mapping of 5-HT1, 5-HT1A, 5-HT1B and 5-HT2 receptors in the rat spinal cord. Brain Res 550:15-23.
    • (1991) Brain Res , vol.550 , pp. 15-23
    • Marlier, L.1    Teilhac, J.R.2    Cerruti, C.3    Privat, A.4
  • 41
    • 0035910346 scopus 로고    scopus 로고
    • Serotonin 2A receptor-like immunoreactivity is detected in astrocytes but not in oligodendrocytes of rat spinal cord
    • Maxishima M, Shiga T, Shutoh F, Hamada S, Maeshima T, Okado N. 2001. Serotonin 2A receptor-like immunoreactivity is detected in astrocytes but not in oligodendrocytes of rat spinal cord. Brain Res 19:270-273.
    • (2001) Brain Res , vol.19 , pp. 270-273
    • Maxishima, M.1    Shiga, T.2    Shutoh, F.3    Hamada, S.4    Maeshima, T.5    Okado, N.6
  • 42
    • 0020570302 scopus 로고
    • Fine structure of serotonin-containing axons in the marginal zone of the rat spinal cord
    • Maxwell DJ, Leranth C, Verhofstad AA. 1983. Fine structure of serotonin-containing axons in the marginal zone of the rat spinal cord. Brain Res 266:253-259.
    • (1983) Brain Res , vol.266 , pp. 253-259
    • Maxwell, D.J.1    Leranth, C.2    Verhofstad, A.A.3
  • 43
    • 0034090696 scopus 로고    scopus 로고
    • Serotoninergic and noradrenergic axonal contacts associated with premotor interneurons in spinal pathways from group II muscle afferents
    • Maxwell DJ, Riddell JS, Jankowska E. 2000. Serotoninergic and noradrenergic axonal contacts associated with premotor interneurons in spinal pathways from group II muscle afferents. Eur J Neurosci 12:1271-1280.
    • (2000) Eur J Neurosci , vol.12 , pp. 1271-1280
    • Maxwell, D.J.1    Riddell, J.S.2    Jankowska, E.3
  • 44
    • 0021176449 scopus 로고
    • Serotoninergic axonal contacts on identified cat spinal dorsal horn neurons and their correlation with nucleus raphe magnus stimulation
    • Miletic V, Hoffert MJ, Ruda MA, Dubner R, Shigenaga Y. 1984. Serotoninergic axonal contacts on identified cat spinal dorsal horn neurons and their correlation with nucleus raphe magnus stimulation. J Comp Neurol 228:129-141.
    • (1984) J Comp Neurol , vol.228 , pp. 129-141
    • Miletic, V.1    Hoffert, M.J.2    Ruda, M.A.3    Dubner, R.4    Shigenaga, Y.5
  • 45
    • 0036277865 scopus 로고    scopus 로고
    • Descending control of pain
    • Millan MJ. 2002. Descending control of pain. Prog Neurobiol 66:355-474.
    • (2002) Prog Neurobiol , vol.66 , pp. 355-474
    • Millan, M.J.1
  • 46
    • 0029963263 scopus 로고    scopus 로고
    • Restoration of extensor excitability in the acute spinal cat by the 5-HT2 agonist DOI
    • Miller JF, Paul KD, Lee RH, Rymer WZ, Heckman CJ. 1996. Restoration of extensor excitability in the acute spinal cat by the 5-HT2 agonist DOI. J Neurophysiol 75:620-628.
    • (1996) J Neurophysiol , vol.75 , pp. 620-628
    • Miller, J.F.1    Paul, K.D.2    Lee, R.H.3    Rymer, W.Z.4    Heckman, C.J.5
  • 47
    • 0031901283 scopus 로고    scopus 로고
    • Apposition of enkephalin- and neurotensin-immunoreactive neurons by serotonin-immunoreactive varicosities in the rat spinal cord
    • Miller KE, Salvatierra AT. 1998. Apposition of enkephalin- and neurotensin-immunoreactive neurons by serotonin-immunoreactive varicosities in the rat spinal cord. Neuroscience 85:837-846.
    • (1998) Neuroscience , vol.85 , pp. 837-846
    • Miller, K.E.1    Salvatierra, A.T.2
  • 48
    • 0037439245 scopus 로고    scopus 로고
    • Ultrastructural localization of serotonin2A receptors in the middle layers of the rat prelimbic prefrontal cortex
    • Miner LA, Backstrom JR, Sanders-Bush E, Sesack SR. 2003. Ultrastructural localization of serotonin2A receptors in the middle layers of the rat prelimbic prefrontal cortex. Neuroscience 116:107-117.
    • (2003) Neuroscience , vol.116 , pp. 107-117
    • Miner, L.A.1    Backstrom, J.R.2    Sanders-Bush, E.3    Sesack, S.R.4
  • 49
    • 0028791387 scopus 로고
    • Presence or absence of TrkA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections
    • Molliver DC, Radeke MJ, Feinstein SC, Snider WD. 1995. Presence or absence of TrkA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections. J Comp Neurol 361:404-416.
    • (1995) J Comp Neurol , vol.361 , pp. 404-416
    • Molliver, D.C.1    Radeke, M.J.2    Feinstein, S.C.3    Snider, W.D.4
  • 50
    • 0036710228 scopus 로고    scopus 로고
    • 5-HT2A receptor subtype in the peripheral branch of sensory fibers is involved in the potentiation of inflammatory pain in rats
    • Okamoto K, Imbe H, Morikawa Y, Itoh M, Sekimoto M, Nemoto K, Senba E. 2002. 5-HT2A receptor subtype in the peripheral branch of sensory fibers is involved in the potentiation of inflammatory pain in rats. Pain 99:133-143.
    • (2002) Pain , vol.99 , pp. 133-143
    • Okamoto, K.1    Imbe, H.2    Morikawa, Y.3    Itoh, M.4    Sekimoto, M.5    Nemoto, K.6    Senba, E.7
  • 51
    • 0022401097 scopus 로고
    • Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors
    • Pazos A, Cortes R, Palacios JM. 1985. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors. Brain Res 346:231-249.
    • (1985) Brain Res , vol.346 , pp. 231-249
    • Pazos, A.1    Cortes, R.2    Palacios, J.M.3
  • 52
    • 0037289839 scopus 로고    scopus 로고
    • 5-HT2 receptors promote plateau potentials in turtle spinal motoneurons by facilitating an L-type calcium current
    • Perrier JF, Hounsgaard J. 2003. 5-HT2 receptors promote plateau potentials in turtle spinal motoneurons by facilitating an L-type calcium current. J Neurophysiol 89:954-959.
    • (2003) J Neurophysiol , vol.89 , pp. 954-959
    • Perrier, J.F.1    Hounsgaard, J.2
  • 53
    • 0029656268 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine receptor subtype messenger RNAs in rat peripheral sensory and sympathetic ganglia: A polymerase chain reaction study
    • Pierce PA, Xie GX, Levine JD, Peroutka SJ. 1996. 5-Hydroxytryptamine receptor subtype messenger RNAs in rat peripheral sensory and sympathetic ganglia: a polymerase chain reaction study. Neuroscience 70:553-559.
    • (1996) Neuroscience , vol.70 , pp. 553-559
    • Pierce, P.A.1    Xie, G.X.2    Levine, J.D.3    Peroutka, S.J.4
  • 55
    • 0028176806 scopus 로고
    • Distribution of the serotonin 5-HT2 receptor family mRNAs: Comparison between 5-HT2A and 5-HT2C receptors
    • Pompeiano M, Palacios JM, Mengod G. 1994. Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors. Brain Res Mol Brain Res 23:163-178.
    • (1994) Brain Res Mol Brain Res , vol.23 , pp. 163-178
    • Pompeiano, M.1    Palacios, J.M.2    Mengod, G.3
  • 57
    • 0019960661 scopus 로고
    • Two types of synaptic glomeruli and their distribution in laminae I-III of the rat spinal cord
    • Ribeiro-da-Silva A, Coimbra A. 1982. Two types of synaptic glomeruli and their distribution in laminae I-III of the rat spinal cord. J Comp Neurol 209:176-186.
    • (1982) J Comp Neurol , vol.209 , pp. 176-186
    • Ribeiro-Da-Silva, A.1    Coimbra, A.2
  • 58
    • 0027389652 scopus 로고
    • Evidence for nonsynaptic serotonergic and noradrenergic innervation of the rat dorsal horn and possible involvement of neuron-glia interactions
    • Ridet JL, Rajaofetra N, Teilhac JR, Geffard M, Privat A. 1993. Evidence for nonsynaptic serotonergic and noradrenergic innervation of the rat dorsal horn and possible involvement of neuron-glia interactions. Neuroscience 52:143-157.
    • (1993) Neuroscience , vol.52 , pp. 143-157
    • Ridet, J.L.1    Rajaofetra, N.2    Teilhac, J.R.3    Geffard, M.4    Privat, A.5
  • 59
    • 0028267960 scopus 로고
    • Direct immunocytochemical localization of 5-hydroxytryptamine receptors in the adult rat spinal cord: A light and electron microscopic study using an anti-idiotypic antiserum
    • Ridet JL, Tamir H, Privat A. 1994. Direct immunocytochemical localization of 5-hydroxytryptamine receptors in the adult rat spinal cord: a light and electron microscopic study using an anti-idiotypic antiserum. J Neurosci Res 38:109-121.
    • (1994) J Neurosci Res , vol.38 , pp. 109-121
    • Ridet, J.L.1    Tamir, H.2    Privat, A.3
  • 60
    • 0344564203 scopus 로고    scopus 로고
    • Subcellular distribution of 5-hydroxytryptamine2A and N-methyl-D-aspartate receptors within single neurons in rat motor and limbic striatum
    • Rodriguez JJ, Garcia DR, Pickel VM. 1999. Subcellular distribution of 5-hydroxytryptamine2A and N-methyl-D-aspartate receptors within single neurons in rat motor and limbic striatum. J Comp Neurol 413:219-231.
    • (1999) J Comp Neurol , vol.413 , pp. 219-231
    • Rodriguez, J.J.1    Garcia, D.R.2    Pickel, V.M.3
  • 61
    • 0027465696 scopus 로고
    • Pharmacological characterization of the effects of 5-hydroxytryptamine and different prostaglandins on peripheral sensory neurons in vitro
    • Rueff A, Dray A. 1993. Pharmacological characterization of the effects of 5-hydroxytryptamine and different prostaglandins on peripheral sensory neurons in vitro. Agents Actions 38:C13-C15.
    • (1993) Agents Actions , vol.38
    • Rueff, A.1    Dray, A.2
  • 63
    • 0034668699 scopus 로고    scopus 로고
    • The role of serotonin in reflex modulation and locomotor rhythm production in the mammalian spinal cord
    • Schmidt BJ, Jordan LM. 2000. The role of serotonin in reflex modulation and locomotor rhythm production in the mammalian spinal cord. Brain Res Bull 53:689-710.
    • (2000) Brain Res Bull , vol.53 , pp. 689-710
    • Schmidt, B.J.1    Jordan, L.M.2
  • 64
    • 0021862734 scopus 로고
    • Topographic principles in the spinal projections of serotonergic and non-serotonergic brainstem neurons in the rat
    • Skagerberg G, Bjorklund A. 1985. Topographic principles in the spinal projections of serotonergic and non-serotonergic brainstem neurons in the rat. Neuroscience 15:445-480.
    • (1985) Neuroscience , vol.15 , pp. 445-480
    • Skagerberg, G.1    Bjorklund, A.2
  • 65
    • 0000972512 scopus 로고    scopus 로고
    • A population of lamina II/IV neurokinin-1-immunoreactive cells are targeted by serotonin-immunoreactive axons in the rat dorsal horn
    • Stewart AO, Maxwell DJ. 1999. A population of lamina II/IV neurokinin-1-immunoreactive cells are targeted by serotonin-immunoreactive axons in the rat dorsal horn. J Physiol 518:166.
    • (1999) J Physiol , vol.518 , pp. 166
    • Stewart, A.O.1    Maxwell, D.J.2
  • 66
    • 0034509625 scopus 로고    scopus 로고
    • Morphological evidence for selective modulation by serotonin of a subpopulation of dorsal horn cells which possess the neurokinin-1 receptor
    • Stewart W, Maxwell DJ. 2000. Morphological evidence for selective modulation by serotonin of a subpopulation of dorsal horn cells which possess the neurokinin-1 receptor. Eur J Neurosci 12:4583-4588.
    • (2000) Eur J Neurosci , vol.12 , pp. 4583-4588
    • Stewart, W.1    Maxwell, D.J.2
  • 67
    • 0026534030 scopus 로고
    • Receptor mediation of 5-HT-induced inflammation and nociception in rats
    • Sufka KJ, Schomburg FM, Giordano J. 1992. Receptor mediation of 5-HT-induced inflammation and nociception in rats. Pharmacol Biochem Behav 41:53-56.
    • (1992) Pharmacol Biochem Behav , vol.41 , pp. 53-56
    • Sufka, K.J.1    Schomburg, F.M.2    Giordano, J.3
  • 68
    • 0027322299 scopus 로고
    • Autoradiographic localization of 5-hydroxytryptaminelA, 5-hydroxytryptaminelB and 5-hydroxytryptamine1C/2 binding sites in the rat spinal cord
    • Thor KB, Nickolaus S, Helke CJ. 1993. Autoradiographic localization of 5-hydroxytryptaminelA, 5-hydroxytryptaminelB and 5-hydroxytryptamine1C/2 binding sites in the rat spinal cord. Neuroscience 55:235-252.
    • (1993) Neuroscience , vol.55 , pp. 235-252
    • Thor, K.B.1    Nickolaus, S.2    Helke, C.J.3
  • 69
    • 0031594975 scopus 로고    scopus 로고
    • 5-HT2A receptor subtype is involved in the thermal hyperalgesic mechanism of serotonin in the periphery
    • Tokunaga A, Saika M, Senba E. 1998. 5-HT2A receptor subtype is involved in the thermal hyperalgesic mechanism of serotonin in the periphery. Pain 76:349-355.
    • (1998) Pain , vol.76 , pp. 349-355
    • Tokunaga, A.1    Saika, M.2    Senba, E.3
  • 70
    • 0025214714 scopus 로고
    • Serotonin immunoreactive boutons form close appositions with respiratory neurons of the dorsal respiratory group in the cat
    • Voss MD, de Castro D, Lipski J, Pilowsky PM, Jiang C. 1990. Serotonin immunoreactive boutons form close appositions with respiratory neurons of the dorsal respiratory group in the cat. J Comp Neurol 295:208-218.
    • (1990) J Comp Neurol , vol.295 , pp. 208-218
    • Voss, M.D.1    De Castro, D.2    Lipski, J.3    Pilowsky, P.M.4    Jiang, C.5
  • 71
    • 0025059607 scopus 로고
    • 5-Hydroxytryptamine responses in neonate rat motoneurones in vitro
    • Wang MY, Dun NJ. 1990. 5-Hydroxytryptamine responses in neonate rat motoneurones in vitro. J Physiol 430:87-103.
    • (1990) J Physiol , vol.430 , pp. 87-103
    • Wang, M.Y.1    Dun, N.J.2
  • 72
    • 0035919857 scopus 로고    scopus 로고
    • Changes of the expression of 5-HT receptor subtype mRNAs in rat dorsal root ganglion by complete Freund's adjuvant-induced inflammation
    • Wu S, Zhu M, Wang W, Wang Y, Li Y, Yew DT. 2001. Changes of the expression of 5-HT receptor subtype mRNAs in rat dorsal root ganglion by complete Freund's adjuvant-induced inflammation. Neurosci Lett 307:183-186.
    • (2001) Neurosci Lett , vol.307 , pp. 183-186
    • Wu, S.1    Zhu, M.2    Wang, W.3    Wang, Y.4    Li, Y.5    Yew, D.T.6
  • 73
    • 0343144796 scopus 로고    scopus 로고
    • Localization and regulation of the delta-opioid receptor in dorsal root ganglia and spinal cord of the rat and monkey: Evidence for association with the membrane of large dense-core vesicles
    • Zhang X, Bao L, Arvidsson U, Elde R, Hökfelt T. 1998. Localization and regulation of the delta-opioid receptor in dorsal root ganglia and spinal cord of the rat and monkey: evidence for association with the membrane of large dense-core vesicles. Neuroscience 82:1225-1242.
    • (1998) Neuroscience , vol.82 , pp. 1225-1242
    • Zhang, X.1    Bao, L.2    Arvidsson, U.3    Elde, R.4    Hökfelt, T.5
  • 74
    • 0035804911 scopus 로고    scopus 로고
    • Expression of 5-HT2A receptor mRNA in rat spinal dorsal horn and some nuclei of brainstem after peripheral inflammation
    • Zhang YQ, Gao X, Ji GC, Wu GC. 2001. Expression of 5-HT2A receptor mRNA in rat spinal dorsal horn and some nuclei of brainstem after peripheral inflammation. Brain Res 900:146-151.
    • (2001) Brain Res , vol.900 , pp. 146-151
    • Zhang, Y.Q.1    Gao, X.2    Ji, G.C.3    Wu, G.C.4


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