The cellular localization of 5-HT(2A) receptors in the spinal cord and spinal ganglia of the adult rat

Brain Research

Volumn 797, Issue 1, 1998, Pages 118-124

  Maeshima, Toru ^a   Ito, Ryuzo ^a   Hamada, Shun ^b   Senzaki, Kouji ^b   Hamaguchi Hamada, Kayoko ^b   Shutoh, Fumihiro ^b   Okado, Nobuo ^b  

^a TSUKUBA UNIVERSITY OF TECHNOLOGY   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

5 HT(2A); DRG; Immunohistochemistry; Receptor; Serotonin; Spinal cord

Indexed keywords

SEROTONIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; GLIA CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOTONEURON; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SEROTONIN BRAIN LEVEL; SPINAL CORD; SPINAL GANGLION;

AGE FACTORS; ANIMALS; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; MALE; NEURONS; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; SPINAL CORD;

EID: 0032557923     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00360-6     Document Type: Article

References (51)

1. 1A receptor in primate brain neurons and glial cells. Neuropsychopharmacology. 14:1996;35-46.
2. Bowker R.M., Westlund K.N., Coulter J.D. Origins of serotonergic projections to the spinal cord in rat: an immunocytochemical-retrograde transport study. Brain Res. 226:1981;187-199.
3. Cardona A., Rudomin P. Activation of brainstem serotoninergic pathways decreases homosynaptic depression of monosynaptic responses of frog spinal motoneurons. Brain Res. 280:1983;373-378.
4. Chen L., Hamaguchi K., Hamada S., Okado N. Regional differences of serotonin-mediated synaptic plasticity in the chicken spinal cord with development and aging. J. Neural Transplant. Plast. 6:1997;41-48.
5. Coote J.H., Macleod V.H., Fleetwood-Walker S., Gilbey M.P. The response of individual sympathetic preganglionic neurones to microelectrophoretically applied endogenous monoamines. Brain Res. 215:1981;135-145.
6. Crone C., Hultborn H., Kiehn O., Mazieres L., Wigström H. Maintained changes in motoneuronal excitability by short-lasting synaptic inputs in the decerebrate cat. J. Physiol. 405:1988;321-343.
7. De Groat W.C., Ryall R.W. An excitatory action of 5-hydroxytryptamine on sympathetic preganglionic neurones. Exp. Brain Res. 3:1967;299-305.
8. 2 receptors in spinal cord in the control of nociceptive responsiveness. Neuropharmacology. 30:1991;727-731.
9. Elliott P., Wallis D.I. Serotonin and L-norepinephrine as mediators of altered excitability in neonatal rat motoneurons studied in vitro. Neuroscience. 47:1992;533-544.
10. 2 receptors throughout the rat central nervous system using quantitative autoradiography. Brain Res. 421:1987;263-279.
11. 3H]LY278584 Brain Res. 553:1991;149-154.
12. 6 receptor-like material in the rat central nervous system. Brain Res. 746:1997;207-219.
13. 2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken. Mol. Brain Res. 54:1998;199-211.
14. 3 receptor binding sites are on capsaicin-sensitive fibres in the rat spinal cord. Eur. J. Pharmacol. 164:1989;315-322.
15. 2A/2C agonist, on monosynaptic transmission in spinalized rats. Brain Res. 738:1996;158-161.
16. Holziv G.G., Shefner S.A., Anderson E.G. Serotonin depolarizes type A and C primary afferents: an intracellular study in bullfrog dorsal root ganglion. Brain Res. 327:1985;71-79.
17. Hoyer D., Clarke D.E., Fozard J.R., Hartig P.R., Martin G.R., Mylecharane E.J., Saxena P.R., Humphrey P.P.A. International Union of Pharmacology Classification of Receptors for 5-hydroxytryptamine (Serotonin). Pharmacol. Rev. 46:1994;157-203.
18. Jackson D.A., White S.R. Receptor subtypes mediating facilitation by serotonin of excitability of spinal motoneurons. Neuropharmacology. 29:1990;787-797.
19. 3 receptors in the rat spinal cord: immunohistochemistry and in situ hybridization. NeuroReport. 6:1995;257-261.
20. 2 receptors in the rat spinal cord. Brain Res. 550:1991;15-23.
21. 1A receptors in the rat central nervous system. J. Comp. Neurol. 365:1996;289-305.
22. Martin G.R., Humphrey P.P.A. Receptors for 5-hydroxytryptamine: current perspectives on classification and nomenclature. Neuropharmacology. 33:1994;261-273.
23. 2 receptor agonists increase spontaneous sympathetic nerve discharge. Eur. J. Pharmacol. 151:1988;113-116.
24. 2 receptor agonists and antagonists on blood pressure, heart rate and sympathetic nerve activity. J. Pharmacol. Exp. Ther. 242:1987;1152-1159.
25. Molineaux S.M., Jessell T.M., Axel R., Julius D. 5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system. Proc. Natl. Acad. Sci. USA. 86:1989;6793-6797.
26. Molokanova E.A., Tamarova Z.A. The effects of dopamine and serotonin on rat dorsal root ganglion neurons: an intracellular study. Neuroscience. 65:1995;859-867.
27. Morales M., Battenberg E., de Lecea L., Sanna P.P., Bloom F.E. Cellular and subcellular immunolocalization of the type 3 serotonin receptor in the rat central nervous system. Mol. Brain Res. 36:1996;251-260.
28. 2A receptor agonist and antagonist in the spinal cord of chicken embryo. Neurosci. Lett. 195:1995;159-162.
29. Okado N., Chen L., Tanatsugu Y., Hamada S., Hamaguchi K. Synaptic loss following removal of serotoninergic fibers in newly hatched and adult chickens. J. Neurobiol. 24:1993;687-698.
30. Pazos A., Corts R., Palacios J.M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain: II. Serotonin-2 receptors. Brain Res. 346:1985;231-249.
31. Pazos A., Palacios J.M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain: I. Serotonin-1 receptors. Brain Res. 346:1985;205-230.
32. Pazos A., Probst A., Palacios J.M. Serotonin receptors in the human brain: IV. Autoradiographic mapping of serotonin-2 receptors. Neuroscience. 21:1987;123-139.
33. Pierce P.A., Xie G.X., Levine J.D., Peroutka S.J. 5-Hydroxytryptamine receptor subtype messenger RNAs in rat peripheral sensory and sympathetic ganglia: a polymerase chain reaction study. Neuroscience. 70:1996;553-559.
34. 2A receptor. Brain Res. 680:1995;9-15.
35. Pompeiano M., Palacios J.M., Mengod G. Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding. J. Neurosci. 12:1992;440-453.
36. 2C receptors. Mol. Brain Res. 23:1994;163-178.
37. Ridet J.L., Tamir H., Privat A. Direct immunocytochemical localization of 5-hydroxytryptamine receptors in the adult rat spinal cord: a light and electron microscopic study using an anti-idiotypic antiserum. J. Neurosci. Res. 38:1994;109-121.
38. Roberts M.H.T., Davies M., Girdlestone D., Foster G.A. Effects of 5-hydroxytryptamine agonists and antagonists on the responses of rat spinal motoneurones to raphe obscurus stimulation. Br. J. Pharmacol. 95:1988;437-448.
39. Skagerberg G., Björklund A. Topographic principles in the spinal projections of serotonergic and non-serotonergic brainstem neurons in the rat. Neuroscience. 15:1985;445-480.
40. Takahashi T., Berger A.J. Direct excitation of rat spinal motoneurones by serotonin. J. Physiol. 423:1990;63-76.
41. 3 receptor mRNA. Proc. Natl. Acad. Sci. USA. 90:1993;1430-1434.
42. 1C/2 binding sites in the rat spinal cord. Neuroscience. 55:1993;235-252.
43. 3 receptors mediate two distinct depolarizing responses in rat dorsal root ganglion neurons. Brain Res. 511:1990;71-79.
44. 3 receptors in rat dorsal root ganglion cells. J. Pharmacol. Exp. Ther. 254:1990;109-115.
45. 1A receptors. Brain Res. 585:1992;212-218.
46. White S.R. A comparison of the effects of serotonin, substance P and thyrotropin-releasing hormone on excitability of rat spinal motoneurons in vivo. Brain Res. 335:1985;63-70.
47. White S.R., Fung S.J. Serotonin depolarizes cat spinal motoneurons in situ and decreases motoneuron afterhyperpolarizing potentials. Brain Res. 502:1989;205-213.
48. White S.R., Neuman R.S. Facilitation of spinal motoneurone excitability by 5-hydroxytryptamine and noradrenaline. Brain Res. 188:1980;119-127.
49. White S.R., Neuman R.S. Pharmacological antagonism of facilitatory but not inhibitory effects of serotonin and norepinephrine on excitability of spinal motoneurons. Neuropharmacology. 22:1983;489-494.
50. Yamazaki J., Ono H., Nagao T. Stimulatory and inhibitory effects of serotonergic hallucinogens on spinal mono- and polysynaptic reflex pathways in the rat. Neuropharmacology. 31:1992;635-642.
51. Zemlan F.P., Behbehani M.M., Murphy R.M. Serotonin receptor subtypes and the modulation of pain transmission. Prog. Brain Res. 77:1988;349-355.