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Volumn 288, Issue 6 57-6, 2005, Pages

Induction of overlapping genes by fasting and a peroxisome proliferator in pigs: Evidence of functional PPARα in nonproliferating species

Author keywords

Clofibric acid; Fatty acid oxidation; Mice; Microarray; Rats

Indexed keywords

CLOFIBRIC ACID; GLYCOGEN; PEROXISOME PROLIFERATOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

EID: 19344364520     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00751.2004     Document Type: Article
Times cited : (71)

References (51)
  • 2
    • 1542335555 scopus 로고    scopus 로고
    • Hepatic de novo synthesis of glucose 6-phosphate is not affected in peroxisome proliferator-activated receptor alpha-deficient mice but is preferentially directed toward hepatic glycogen stores after a short-term fast
    • Bandsma RH, Van Dijk TH, Harmsel At A, Kok T, Reijngoud DJ, Staels B, and Kuipers F. Hepatic de novo synthesis of glucose 6-phosphate is not affected in peroxisome proliferator-activated receptor alpha-deficient mice but is preferentially directed toward hepatic glycogen stores after a short-term fast. J Biol Chem 279: 8930-8937, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 8930-8937
    • Bandsma, R.H.1    Van Dijk, T.H.2    Harmsel At, A.3    Kok, T.4    Reijngoud, D.J.5    Staels, B.6    Kuipers, F.7
  • 4
    • 0029671098 scopus 로고    scopus 로고
    • L-Lactate dehydrogenase A4- and A3B isoforms are bona fide peroxisomal enzymes in rat liver. Evidence for involvement in intraperoxisomal NADH reoxidation
    • Baumgart E, Fahimi HD, Stich A, and Volkl A. L-Lactate dehydrogenase A4- and A3B isoforms are bona fide peroxisomal enzymes in rat liver. Evidence for involvement in intraperoxisomal NADH reoxidation. J Biol Chem 271: 3846-3855, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 3846-3855
    • Baumgart, E.1    Fahimi, H.D.2    Stich, A.3    Volkl, A.4
  • 6
    • 0037245672 scopus 로고    scopus 로고
    • Generation and sequence characterization of a normalized cDNA library from swine ovarian follicles
    • Caetano AR, Johnson RK, and Pomp D. Generation and sequence characterization of a normalized cDNA library from swine ovarian follicles. Mamm Genome 14: 65-70, 2003.
    • (2003) Mamm Genome , vol.14 , pp. 65-70
    • Caetano, A.R.1    Johnson, R.K.2    Pomp, D.3
  • 7
    • 0035184941 scopus 로고    scopus 로고
    • Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis
    • Cherkaoui-Malki M, Meyer K, Cao WQ, Latruffe N, Yeldandi AV, Rao MS, Bradfield CA, and Reddy JK. Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis. Gene Expr 9: 291-304, 2001.
    • (2001) Gene Expr , vol.9 , pp. 291-304
    • Cherkaoui-Malki, M.1    Meyer, K.2    Cao, W.Q.3    Latruffe, N.4    Yeldandi, A.V.5    Rao, M.S.6    Bradfield, C.A.7    Reddy, J.K.8
  • 8
    • 0037025390 scopus 로고    scopus 로고
    • WY14,643, a peroxisome proliferator-activated receptor alpha (PPARalpha) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatrophic A-ZIP/F-1 mice
    • Chou CJ, Haluzik M, Gregory C, Dietz KR, Vinson C, Gavrilova O, and Reitman ML. WY14,643, a peroxisome proliferator-activated receptor alpha (PPARalpha) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatrophic A-ZIP/F-1 mice. J Biol Chem 277: 24484-24489, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 24484-24489
    • Chou, C.J.1    Haluzik, M.2    Gregory, C.3    Dietz, K.R.4    Vinson, C.5    Gavrilova, O.6    Reitman, M.L.7
  • 10
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman BM, Chen J, and Evans RM. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci USA 94: 4312-4317, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 12
    • 0037205918 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor alpha (PPAR alpha): Role in hepatocarcinogenesis
    • Gonzalez FJ. The peroxisome proliferator-activated receptor alpha (PPAR alpha): role in hepatocarcinogenesis. Mol Cell Endocrinol 193: 71-79, 2002.
    • (2002) Mol Cell Endocrinol , vol.193 , pp. 71-79
    • Gonzalez, F.J.1
  • 13
    • 0345829924 scopus 로고    scopus 로고
    • Comparative effect of fenofibrate on hepatic desaturases in wild-type and peroxisome proliferator-activated receptor alpha-deficient mice
    • Guillou H, Martin P, Jan S, D'Andrea S, Roulet A, Catheline D, Rioux V, Pineau T, and Legrand P. Comparative effect of fenofibrate on hepatic desaturases in wild-type and peroxisome proliferator-activated receptor alpha-deficient mice. Lipids 37: 981-989, 2002.
    • (2002) Lipids , vol.37 , pp. 981-989
    • Guillou, H.1    Martin, P.2    Jan, S.3    D'Andrea, S.4    Roulet, A.5    Catheline, D.6    Rioux, V.7    Pineau, T.8    Legrand, P.9
  • 14
    • 0036784130 scopus 로고    scopus 로고
    • Clofibrate improves glucose tolerance in fat-fed rats but decreases hepatic glucose consumption capacity
    • Gustafson LA, Kuipers F, Wiegman C, Sauerwein HP, Romijn JA, and Meijer AJ. Clofibrate improves glucose tolerance in fat-fed rats but decreases hepatic glucose consumption capacity. J Hepatol 37: 425-431, 2002.
    • (2002) J Hepatol , vol.37 , pp. 425-431
    • Gustafson, L.A.1    Kuipers, F.2    Wiegman, C.3    Sauerwein, H.P.4    Romijn, J.A.5    Meijer, A.J.6
  • 15
    • 0034666132 scopus 로고    scopus 로고
    • Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting
    • Hashimoto T, Cook WS, Qi C, Yeldandi AV, Reddy JK, and Rao MS. Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting. J Biol Chem 275: 28918-28928, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 28918-28928
    • Hashimoto, T.1    Cook, W.S.2    Qi, C.3    Yeldandi, A.V.4    Reddy, J.K.5    Rao, M.S.6
  • 16
    • 0036915006 scopus 로고    scopus 로고
    • Delayed induction of delta-6 and delta-5 desaturases by a peroxisome proliferator
    • He WS, Nara TY, and Nakamura MT. Delayed induction of delta-6 and delta-5 desaturases by a peroxisome proliferator. Biochem Biophys Res Commun 299: 832-838, 2002.
    • (2002) Biochem Biophys Res Commun , vol.299 , pp. 832-838
    • He, W.S.1    Nara, T.Y.2    Nakamura, M.T.3
  • 17
    • 0033559336 scopus 로고    scopus 로고
    • Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: A control enzyme in ketogenesis
    • Hegardt FG. Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: a control enzyme in ketogenesis. Biochem J 338: 569-582, 1999.
    • (1999) Biochem J , vol.338 , pp. 569-582
    • Hegardt, F.G.1
  • 18
    • 0032941350 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha: Role in rodent liver cancer and species differences
    • Holden PR and Tugwood JD. Peroxisome proliferator-activated receptor alpha: role in rodent liver cancer and species differences. J Mol Endocrinol 22: 1-8, 1999.
    • (1999) J Mol Endocrinol , vol.22 , pp. 1-8
    • Holden, P.R.1    Tugwood, J.D.2
  • 19
    • 0035958960 scopus 로고    scopus 로고
    • Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor alpha in HepG2 cells
    • Hsu MH, Savas U, Griffin KJ, and Johnson EF. Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor alpha in HepG2 cells. J Biol Chem 276: 27950-27958, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 27950-27958
    • Hsu, M.H.1    Savas, U.2    Griffin, K.J.3    Johnson, E.F.4
  • 20
    • 0033597211 scopus 로고    scopus 로고
    • Characterization of the 70-kDa peroxisomal membrane protein, an ATP binding cassette transporter
    • Imanaka T, Aihara K, Takano T, Yamashita A, Sato R, Suzuki Y, Yokota S, and Osumi T. Characterization of the 70-kDa peroxisomal membrane protein, an ATP binding cassette transporter. J Biol Chem 274: 11968-11976, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 11968-11976
    • Imanaka, T.1    Aihara, K.2    Takano, T.3    Yamashita, A.4    Sato, R.5    Suzuki, Y.6    Yokota, S.7    Osumi, T.8
  • 21
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I and Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347: 645-650, 1990.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 22
    • 0025311298 scopus 로고
    • Peroxisome proliferators enhance linoleic acid metabolism in rat liver: Increased biosynthesis of ω6 polyunsaturated fatty acids
    • Kawashima Y, Musoh K, and Kozuka H. Peroxisome proliferators enhance linoleic acid metabolism in rat liver: increased biosynthesis of ω6 polyunsaturated fatty acids. J Biol Chem 265: 9170-9175, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 9170-9175
    • Kawashima, Y.1    Musoh, K.2    Kozuka, H.3
  • 23
    • 0032699670 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
    • Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, and Wahli W. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 103: 1489-1498, 1999.
    • (1999) J Clin Invest , vol.103 , pp. 1489-1498
    • Kersten, S.1    Seydoux, J.2    Peters, J.M.3    Gonzalez, F.J.4    Desvergne, B.5    Wahli, W.6
  • 25
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferates signaling pathways through heterodimer formation of their receptors
    • Kliewer SA, Umesono K, Noonan DJ, Heyman RA, and Evans RM. Convergence of 9-cis retinoic acid and peroxisome proliferates signaling pathways through heterodimer formation of their receptors. Nature 358: 771-774, 1992.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 27
    • 0035943681 scopus 로고    scopus 로고
    • Differential gene regulation in human vs. rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR)α: PPARα fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expression
    • Lawrence JW, Li Y, Chen S, DeLuca JG, Berger JP, Umbenhauer DR, Moller DE, and Zhou G. Differential gene regulation in human vs. rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR)α: PPARα fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expression. J Biol Chem 276: 31521-31527, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 31521-31527
    • Lawrence, J.W.1    Li, Y.2    Chen, S.3    DeLuca, J.G.4    Berger, J.P.5    Umbenhauer, D.R.6    Moller, D.E.7    Zhou, G.8
  • 28
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee SS, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, and Gonzalez FJ. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 15: 3012-3022, 1995.
    • (1995) Mol Cell Biol , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 29
    • 0033594980 scopus 로고    scopus 로고
    • A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: The PPARalpha-null mouse as a model of fatty acid oxidation disorders
    • Leone TC, Weinheimer CJ, and Kelly DP. A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci USA 96: 7473-7478, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7473-7478
    • Leone, T.C.1    Weinheimer, C.J.2    Kelly, D.P.3
  • 30
    • 12344273935 scopus 로고    scopus 로고
    • Regulation of highly unsaturated fatty acid synthesis: A new physiological role of peroxisome proliferator-activated receptor alpha
    • Li Y, Nara TY, and Nakamura MT. Regulation of highly unsaturated fatty acid synthesis: a new physiological role of peroxisome proliferator-activated receptor alpha (abstract). FASEB J 18: A863, 2004.
    • (2004) FASEB J , vol.18
    • Li, Y.1    Nara, T.Y.2    Nakamura, M.T.3
  • 31
    • 0014738371 scopus 로고
    • Determination of glycogen in small tissue samples
    • Lo S, Russell JC, and Taylor AW. Determination of glycogen in small tissue samples. J Appl Physiol 28: 234-236, 1970.
    • (1970) J Appl Physiol , vol.28 , pp. 234-236
    • Lo, S.1    Russell, J.C.2    Taylor, A.W.3
  • 35
    • 0029823995 scopus 로고    scopus 로고
    • Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression
    • Miller CW and Ntambi JM. Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression. Proc Natl Acad Sci USA 93: 9443-9448, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9443-9448
    • Miller, C.W.1    Ntambi, J.M.2
  • 36
    • 0041831047 scopus 로고    scopus 로고
    • Analysis of the critical structural determinant(s) of species-selective peroxisome proliferator-activated receptor alpha (PPAR alpha)-activation by phenylpropanoic acid-type PPAR alpha agonists
    • Miyachi H and Uchiki H. Analysis of the critical structural determinant(s) of species-selective peroxisome proliferator-activated receptor alpha (PPAR alpha)-activation by phenylpropanoic acid-type PPAR alpha agonists. Bioorg Med Chem Lett 13: 3145-3149, 2003.
    • (2003) Bioorg Med Chem Lett , vol.13 , pp. 3145-3149
    • Miyachi, H.1    Uchiki, H.2
  • 37
    • 3142753961 scopus 로고    scopus 로고
    • Structure, function, and dietary regulation of Δ6, Δ5, and Δ9 desaturases
    • Nakamura MT and Nara TY. Structure, function, and dietary regulation of Δ6, Δ5, and Δ9 desaturases. Annu Rev Nutr 24: 345-376, 2004.
    • (2004) Annu Rev Nutr , vol.24 , pp. 345-376
    • Nakamura, M.T.1    Nara, T.Y.2
  • 38
    • 0036039741 scopus 로고    scopus 로고
    • The E-box like sterol regulatory element mediates the suppression of human delta-6 desaturase gene by highly unsaturated fatty acids
    • Nara TY, He WS, Tang C, Clarke SD, and Nakamura MT. The E-box like sterol regulatory element mediates the suppression of human delta-6 desaturase gene by highly unsaturated fatty acids. Biochem Biophys Res Commun 296: 111-117, 2002.
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 111-117
    • Nara, T.Y.1    He, W.S.2    Tang, C.3    Clarke, S.D.4    Nakamura, M.T.5
  • 39
  • 40
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet
    • Reeves PG, Nielsen FH, and Fahey GC. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet. J Nutr 123: 1939-1951, 1993.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey, G.C.3
  • 41
    • 0027679426 scopus 로고
    • Dietary clofibric acid increases intestinal fatty acid binding protein activity and apparent lipid digestibility in weanling swine
    • Reinhart GA, Mahan DC, Lepine AJ, Simmen FA, and Moore BE. Dietary clofibric acid increases intestinal fatty acid binding protein activity and apparent lipid digestibility in weanling swine. J Anim Sci 71: 2693-2699, 1993.
    • (1993) J Anim Sci , vol.71 , pp. 2693-2699
    • Reinhart, G.A.1    Mahan, D.C.2    Lepine, A.J.3    Simmen, F.A.4    Moore, B.E.5
  • 42
    • 0031041670 scopus 로고    scopus 로고
    • Clofibrate feeding to Sprague-Dawley rats increases endogenous biosynthesis of oxalate and causes hyperoxaluria
    • Sharma V and Schwille PO. Clofibrate feeding to Sprague-Dawley rats increases endogenous biosynthesis of oxalate and causes hyperoxaluria. Metabolism 46: 135-139, 1997.
    • (1997) Metabolism , vol.46 , pp. 135-139
    • Sharma, V.1    Schwille, P.O.2
  • 43
    • 0031049745 scopus 로고    scopus 로고
    • The cytochrome P450 4 (CYP4) family
    • Simpson AE. The cytochrome P450 4 (CYP4) family. Gen Pharmacol 28: 351-359, 1997.
    • (1997) Gen Pharmacol , vol.28 , pp. 351-359
    • Simpson, A.E.1
  • 44
    • 0035948577 scopus 로고    scopus 로고
    • Tissue distribution of porcine peroxisome proliferator-activated receptor alpha: Detection of an alterntively spliced mRNA
    • Sundvold H, Grindflek E, and Lien S. Tissue distribution of porcine peroxisome proliferator-activated receptor alpha: detection of an alterntively spliced mRNA. Gene 273: 105-113, 2001.
    • (2001) Gene , vol.273 , pp. 105-113
    • Sundvold, H.1    Grindflek, E.2    Lien, S.3
  • 45
    • 0040799893 scopus 로고    scopus 로고
    • Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2
    • Tabor DE, Kim JB, Spiegelman BM, and Edwards PA. Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2. J Biol Chem 274: 20603-20610, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 20603-20610
    • Tabor, D.E.1    Kim, J.B.2    Spiegelman, B.M.3    Edwards, P.A.4
  • 46
    • 0142010520 scopus 로고    scopus 로고
    • Regulation of human delta-6 desaturase gene transcription: Identification of a functional direct repeat-1 element
    • Tang C, Cho HP, Nakamura MT, and Clarke SD. Regulation of human delta-6 desaturase gene transcription: identification of a functional direct repeat-1 element. J Lipid Res 44: 686-695, 2003.
    • (2003) J Lipid Res , vol.44 , pp. 686-695
    • Tang, C.1    Cho, H.P.2    Nakamura, M.T.3    Clarke, S.D.4
  • 47
    • 0031915653 scopus 로고    scopus 로고
    • A peroxisome proliferator-activated receptor-alpha (PPARalpha) cDNA cloned from guinea-pig liver encodes a protein with similar properties to the mouse PPARα: Implications for species differences in responses to peroxisome proliferators
    • Tugwood JD, Holden PR, James NH, Prince RA, and Roberts RA. A peroxisome proliferator-activated receptor-alpha (PPARalpha) cDNA cloned from guinea-pig liver encodes a protein with similar properties to the mouse PPARα: implications for species differences in responses to peroxisome proliferators. Arch Toxicol 72: 169-177, 1998.
    • (1998) Arch Toxicol , vol.72 , pp. 169-177
    • Tugwood, J.D.1    Holden, P.R.2    James, N.H.3    Prince, R.A.4    Roberts, R.A.5
  • 48
    • 0000005098 scopus 로고
    • D-3-hydroxybutyrate
    • edited by Bergmeyer H. New York: Academic Press
    • Williamson D, and Mellanby J. D-3-hydroxybutyrate. In: Methods of Enzymatic Analysis (2nd ed.), edited by Bergmeyer H. New York: Academic Press, 1974, p. 1836-1839.
    • (1974) Methods of Enzymatic Analysis (2nd Ed.) , pp. 1836-1839
    • Williamson, D.1    Mellanby, J.2
  • 49
    • 0032995560 scopus 로고    scopus 로고
    • The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: Significance for species differences in response to PPs
    • Woodyatt NJ, Lambe KG, Myers KA, Tugwood JD, and Roberts RA. The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences in response to PPs. Carcinogenesis 20: 369-372, 1999.
    • (1999) Carcinogenesis , vol.20 , pp. 369-372
    • Woodyatt, N.J.1    Lambe, K.G.2    Myers, K.A.3    Tugwood, J.D.4    Roberts, R.A.5
  • 50
    • 0034282947 scopus 로고    scopus 로고
    • Starvation increases the amount of pyruvate dehydrogenase kinase in several mammalian tissues
    • Wu P, Blair PV, Sato J, Jaskiewicz J, Popov KM, and Harris RA. Starvation increases the amount of pyruvate dehydrogenase kinase in several mammalian tissues. Arch Biochem Biophys 381: 1-7, 2000.
    • (2000) Arch Biochem Biophys , vol.381 , pp. 1-7
    • Wu, P.1    Blair, P.V.2    Sato, J.3    Jaskiewicz, J.4    Popov, K.M.5    Harris, R.A.6


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