The proteasome and the delicate balance between destruction and rescue

PLoS Biology

Volumn 2, Issue 1, 2004, Pages

  Glickman, Michael H ^a   Adir, Noam ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN DERIVATIVE; UBIQUITIN; BACTERIAL PROTEIN; METALLOPROTEINASE; PROTEASOME; UBIQUITIN PROTEIN LIGASE;

AMINO ACID SEQUENCE; HYDROLYSIS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN TARGETING; REVIEW; UBIQUITINATION; ANIMAL; BIOLOGICAL MODEL; METABOLISM;

ANIMALS; BACTERIAL PROTEINS; METALLOPROTEASES; MODELS, BIOLOGICAL; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 19344362846     PISSN: 15449173     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pbio.0020013     Document Type: Review

References (24)

1. Ambroggio XI, Rees DC, Deshaies RJ (2003) JAMM: A metalloprotease-like zinc site in the proteasome and signalosome. PLoS Biol 2: e210.1371/journal. pbio.0020002. Find this article online
2. Bech-Otschir D, Seeger M, Dubiel W (2002) The COP9 signalosome: At the interface between signal transduction and ubiquitin-dependent proteolysis. J Cell Sci 115: (Pt 3) 467-473. Find this article online
3. Borodovsky A, Kessler BM, Casagrande R, Overkleeft HS, Wilkinson KD (2001) A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14. EMBO J 20: 5187-5196. Find this article online
4. Cope GA, Deshaies RJ (2003) COP9 signalosome: A multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 114: 663-671. Find this article online
5. Eytan E, Armon T, Heller H, Beck S, Hershko A (1993) Ubiquitin C-terminal hydrolase activity associated with the 26S protease complex. J Biol Chem 268: 4668-4674. Find this article online
6. Forster A, Hill CP (2003) Proteasome degradation: Enter the substrate. Trends Cell Biol 13: 550-553. Find this article online
7. Glickman MH, Ciechanover A (2002) The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction. Physiol Rev 82: 373-428. Find this article online
8. Glickman MH, Rubin DM, Coux O, Wefes I, Pfeifer G (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9/signalosome and eIF3. Cell 94: 615-623. Find this article online
9. Guterman A, Glickman MH (2003) Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome. J Biol Chem In press. [2003 Oct 27 Epub ahead of print].
10. Hartmann-Petersen R, Seeger M, Gordon C (2003) Transferring substrates to the 26S proteasome. Trends Biochem Sci 28: 26-31. Find this article online
11. Hoelzl H, Kapelari B, Kellermann J, Seemuller E, Sumegi M (2000) The regulatory complex of Drosophila melanogaster 26S proteasomes: Subunit composition and localization of a deubiquitylating enzyme. J Cell Biol 150: 119-130. Find this article online
12. Kim JH, Park KC, Chung SS, Bang O, Chung CH (2003) Deubiquitinating enzymes as cellular regulators. J Biochem (Tokyo) 134: 9-18. Find this article online
13. Lam YA, Xu W, DeMartino GN, Cohen RE (1997) Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome. Nature 385: 737-740. Find this article online
14. Lam YA, Lawson TG, Velayutham M, Zweier JL, Pickart CM (2002) A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal. Nature 416: 763-767. Find this article online
15. Legget DS, Hanna J, Borodovsky A, Crossas B, Schmidt M (2002) Multiple associated proteins regulate proteasome structure and function. Mol Cell 10: 495-507. Find this article online
16. Li L, Deng XW (2003) The COP9 signalosome: An alternative lid for the 26S proteasome? Trends Cell Biol 13: 507-509. Find this article online
17. +, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function. BMC Biochem 3: 28. Find this article online
18. Papa FR, Amerik AY, Hochstrasser M (1999) Interaction of the Doa4 deubiquitinating enzyme with the yeast 26S proteasome. Mol Biol Cell 10: 741-756. Find this article online
19. Pickart CM (2001) Mechanisms underlying ubiquitination. Annu Rev Biochem 70: 503-533. Find this article online
20. Thrower JS, Hoffman L, Rechsteiner M, Pickart C (2000) Recognition of the polyubiquitin proteolytic signal. EMBO J 19: 94-102. Find this article online
21. Tran HJ, Allen MD, Lowe J, Bycroft M (2003) Structure of the Jab1/MPN domain and its implications for proteasome function. Biochemistry 42: 11460-11465. Find this article online
22. Verma R, Aravind L, Oania R, McDonald WH, Yates JR (2002) Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome. Science 298: 611-615. Find this article online
23. Wing S (2003) Deubiquitinating enzymes: The importance of driving in reverse along the ubiquitin-proteasome pathway. Int J Biochem Cell Biol 35: 590-605. Find this article online
24. Yao T, Cohen RE (2002) A cryptic protease couples deubiquitination and degradation by the proteasome. Nature 419: 403-407. Find this article online